United States
Germany
Japan
United Kingdom
China
CNOT8 (NM_004779) Human Untagged Clone
CAT＃: SC117172
CNOT8 (untagged)-Human CCR4-NOT transcription complex, subunit 8 (CNOT8)
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAF1; Caf1b; CALIF; hCAF1; POP2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_004779, the custom clone sequence may differ by one or more nucleotides
ATGCCTGCAGCACTTGTGGAGAATAGCCAGGTTATCTGTGAAGTGTGGGCCAGTAATCTAGAAGAAGAGA TGAGGAAGATCCGAGAAATCGTGCTCAGTTACAGTTATATTGCCATGGACACAGAATTTCCAGGTGTTGT GGTGCGACCAATTGGTGAATTTCGTAGTTCCATAGATTACCAATATCAGCTTCTGCGGTGCAATGTTGAC CTTTTAAAAATTATCCAGCTGGGCCTTACATTCACAAATGAGAAGGGAGAGTATCCTTCTGGAATCAATA CTTGGCAGTTCAATTTCAAATTTAACCTTACAGAGGACATGTACTCCCAGGATTCCATAGATCTCCTTGC TAACTCAGGACTACAGTTTCAGAAGCATGAAGAGGAAGGGATTGACACACTGCACTTTGCAGAGCTGCTT ATGACATCAGGAGTGGTTCTCTGTGACAATGTCAAATGGCTTTCATTTCATAGTGGCTATGATTTTGGCT ATATGGTAAAGTTGCTTACAGATTCTCGTTTGCCAGAAGAGGAACATGAATTCTTTCATATTCTGAACCT TTTCTTCCCATCCATTTATGATGTGAAATACCTGATGAAGAGCTGCAAAAATCTTAAGGGAGGTCTTCAG GAAGTTGCTGATCAGTTGGATTTGCAGAGGATTGGAAGGCAGCACCAGGCAGGCTCAGACTCACTGCTGA CAGGAATGGCTTTCTTTAGGATGAAAGAGTTGTTTTTTGAGGACAGCATTGATGATGCCAAGTACTGTGG GCGGCTCTATGGCTTAGGCACAGGAGTGGCCCAGAAGCAGAATGAGGATGTGGACTCTGCCCAGGAGAAG ATGAGCATCCTGGCGATTATCAACAACATGCAGCAGTGA >OriGene 5' read for NM_004779 unedited
NGTTAGAATTTGTATACGACTCACTATAGGCGGCCGCGCAATTCGCACGAGGGCCGTCGC CGCCGTCGGGGAGTCAGCCCGCCAGCCCGCCAGCTCGTCAGCCCGCCAGCCAGCGCTTCG CGGGCCCTGTCGGTCCCGATCAGACCAAACATTGTCTGGCTTGCACTGTAAAACTAGTTA GCTGAAGACGACTTCTCAGGTTTCTTCAGGATGCCTGCAGCACTTGTGGAGAATAGCCAG GTTATCTGTGAAGTGTGGGCCAGTAATCTAGAAGAAGAGATGAGGAAGATCCGAGAAATC GTGCTCAGTTACAGTTATATTGCCATGGACACAGAATTTCCAGGTGTTGTGGTGCGACCA ATTGGTGAATTTCGTAGTTCCATAGATTACCAATATCAGCTTCTGCGGTGCAATGTTGAC CTTTTAAAAATTATCCAGCTGGGCCTTACATTCACAAATGAGAAGGGAGAGTATCCTTCT GGAATCAATACTTGGCAGTTCAATTTCAAATTTAACCTTACTGGCTATGATTTTGGCTAT ATGGTAAAGTTGCTTACAGATTCTCGTTTGCCAGAAGAGGAACATGAATTCTTTCATATT CTGAACCTTTTCTTCCCATCCATTTATGATGTGAAATACCCTGATGAAGAGCTGCAAAAA TCTTAAGGGAGGTCTTCAGGAAGTTGCTGATCAGTTGGATTTGCAGAGGATTTGGAGGCA GCACCCAGCAGGCTCAGACTCACTGCTGACAGGAATGGCTTTCTTTACGATGAAAGAAGT GTTTTTTGAGGACAGCATTGATGATGCCAAGTACTGTGGGCCGCTCTATGGCTTTAGCCC AGGAGTGGCCCAAAGCAGATGAAGATGGGGCTCTGCCCAGNAAAGATGAGCTCCCTGCGA TATCAACAC >OriGene 3' read for NM_004779 unedited
GACCGCGGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTGGGGAAAAAAAAAATTTTTTTTTTCCAAATTTAA AACCTTAATTGTTTTTTCAAGCCTTTTAAAAACCCCCTTATAAAACTTGGCATTTTTTAA ACATTTCAAAATGGGGTTCCCCTAAGCTTTTAAAAAGGAAAACCCTTTTTTTCCTTGGGG GGGGTACCCATTTTTTCTTTCCCCCATCCAAAGGGGGGTTTGGGTTTTGAAAATGGCCCT TCTGGGGGCCTTTAAAAAAAAACAAAATGCTTTTGAAAAGACTAACTTTAAAAAAAAAAG GCCTGGGCTTTCTACCCCCGGTGGGGGGTTTTTCTCCCAAACAACTCAAAAACCCCAATT TTTTTTCTGGCCGGTTAAAAGGAACCCCCCTTACTTTTTAAAAAAACATTTCTGGTACCC ACATTAAACCCTTTCCCCCACGGTTCAAGGTTGGTGGGAGGGAAAATTAAAAAATAATGG GGTTTAAAAAGGGGGGAAACCCAAAGACCCTTTGGAATCCCCTTTCTGGAAATACAACAG ACCTGGCCCCAAAAACTGGGCTTTCCAGGTTCCTTCTGGGACAAAACCCGGGTATTTTTT TGGGCCAAAATTTCAAAAGGATTTCAAAGATGCCTTTGGGACAGCAAACCTGAATGCGCA ATGGGACACAGACTTTAAAAAGGCTTCAGGGGGCACACTTATTCTGGAGTTTCATGAATG AAGGGGGACGAATTCGAAAATGGGTGGTTTTAGGTCATTTTTTGGCTCTAAATTCAGCCC GAGCAATTCTTTCCTTATGTATTTGGAAAGAAGACTCCAAGGGGGGGGAAAGCCAGGTCC CGAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004779 |
| Insert Size | 2300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004779.4, NP_004770.4 |
| RefSeq Size | 2550 bp |
| RefSeq ORF | 879 bp |
| Locus ID | 9337 |
| UniProt ID | Q9UFF9 |
| Domains | CAF1 |
| Protein Families | Transcription Factors |
| Protein Pathways | RNA degradation |
| Gene Summary | Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1 and 2 encode the same isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200225 | CNOT8 (Myc-DDK-tagged)-Human CCR4-NOT transcription complex, subunit 8 (CNOT8) |
CNY 2,400.00 |
|
| RC200225L3 | Lenti ORF clone of Human CCR4-NOT transcription complex, subunit 8 (CNOT8), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200225L4 | Lenti ORF clone of Human CCR4-NOT transcription complex, subunit 8 (CNOT8), mGFP tagged |
CNY 5,890.00 |
|
| RG200225 | CNOT8 (tGFP-tagged) - Human CCR4-NOT transcription complex, subunit 8 (CNOT8) |
CNY 4,000.00 |
