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ROCK2 (NM_004850) Human Untagged Clone
CAT＃: SC117098
ROCK2 (untagged)-Human Rho-associated, coiled-coil containing protein kinase 2 (ROCK2)
CNY 9,504.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ROCK-II |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_004850 edited
TGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCATTTAGGTGACACTA TAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGGGACCAGC GGACCGGCGGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCG GCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCGGGCCCCTGGGAGCAGCCCCCAG GCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGG AGTCCCGGCCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGA GCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCATGAGCCGGCCCCCGCCGACGGG GAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAG GAAGCTGGAGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGGA TGGCTTAAATTCCTTGGTCCTTGATTTAGATTTTCCTGCTTTGAGGAAAAACAAGAACAT AGATAATTTCTTAAATAGATATGAGAAAATTGTGAAAAAAATCAGAGGTCTACAGATGAA GGCAGAAGACTATGATGTTGTAAAAGTTATTGGAAGAGGTGCTTTTGGTGAAGTGCAGTT GGTTCGTCACAAGGCATCGCAGAAGGTTTATGCTATGAAGCTTCTTAGTAAGTTTGAAAT GATAAAAAGATCAGATTCTGCCTTTTTTTGGGAAGAAAGAGATATTATGGCCTTTGCCAA TAGCCCCTGGGTGGTTCAGCTTTTTTATGCCTTTCAAGATGATAGGTATCTGTACATGGT AATGGAGTACATGCCTGGTGGAGACCTTGTAAACCTTATGAGTAATTATGATGTGCCTGA AAAATGGGCCAAATTTTACACTGCTGAAGTTGTTCTTGCTCTGGATGCAATACACTCCAT GGGTTTAATACACAGAGATGTGAAGCCTGACAACATGCTCTTGGATAAACATGGACATCT AAAATTAGCAGATTTTGGCACGTGTATGAAGATGGATGAAACAGGCATGGTACATTGTGA TACAGCAGTTGGAACACCGGATTATATATCACCTGAGGTTCTGAAATCACAAGGGGGTGA TGGTTTCTATGGGCGAGAATGTGATTGGTGGTCTGTAGGTGTTTTCCTTTATGAGATGCT AGTGGGGGATACTCCATTTTATGCGGATTCACTTGTAGGAACATATAGCAAAATTATGGA TCATAAGAATTCACTGTGTTTCCCTGAAGATGCAGAAATTTCCAAACATGCAAAGAATCT CATCTGTGCTTTCTTAACAGATAGGGAGGTACGACTTGGGAGAAATGGGGTGGAAGAAAT CAGACAGCATCCTTTCTTTAAGAATGATCAGTGGCATTGGGATAACATAAGAGAAACGGC AGCTCCTGTAGTACCTGAACTCAGCAGTGACATAGACAGCAGCAATTTCGATGACATTGA AGATGACAAAGGAGATGTAGAAACCTTCCCAATTCCTAAAGCTTTTGTTGGAAATCAGCT GCCTTTCATCGGATTTACCTACTATAGAGAAAATTTATTATTAAGTGACTCTCCATCTTG TAGAGAAACTGATTCCATACAATCAAGGAAAAATGAAGAAAGTCAAGAGATTCAGAAAAA ACTGTATACATTAGAAGAACATCTTAGCAATGAGATGCAAGCCAAAGAGGAACTGGAACA GAAGTGCAAATCTGTTAATACTCGCCTAGAAAAAACAGCAAAGGAGCTAGAAGAGGAGAT TACCTTACGGAAAAGTGTGGAATCAGCATTAAGACAGTTAGAAAGAGAAAAGGCGCTTCT TCAGCACAAAAATGCAGAATATCAGAGGAAAGCTGATCATGAAGCAGACAAAAAACGAAA TTTGGAAAATGATGTTAACAGCTTAAAAGATCAACTTGAAGATTTGAAAAAAAGAAATCA AAACTCTCAAATATCCACTGAGAAAGTGAATCAACTCCAGAGACAACTGGATGAAACCAA TGCTTTACTGCGAACAGAGTCTGATACTGCAGCCCGGTTAAGGAAAACCCAGGCAGAAAG TTCAAAACAGATTCAGCAGCTGGAATCTAACAATAGAGATCTACAAGATAAAAACTGCCT GCTGGAGACTGCCAAGTTAAAACTTGAAAAGGAATTTATCAATCTTCAGTCAGCTCTAGA ATCTGAAAGGAGGGATCGAACCCATGGATCAGAGATAATTAATGATTTACAAGGTAGAAT ATGTGGCCTAGAAGAAGATTTAAAGAACGGCAAAATCTTACTAGCGAAAGTAGAACTGGA GAAGAGACAACTTCAGGAGAGATTTACTGATTTGGAAAAGGAAAAAAGCAACATGGAAAT AGATATGACATACCAACTAAAAGTTATACAGCAGAGCCTAGAACAAGAAGAAGCTGAACA TAAGGCCACAAAGGCACGACTAGCAGATAAAAATAAGATCTATGAGTCCATCGAAGAAGC CAAATCAGAAGCCATGAAAGAAATGGAGAAGAAGCTCTTGGAGGAAAGAACTTTAAAACA GAAAGTGGAGAACCTATTGCTAGAAGCTGAGAAAAGATGTTCTCTATTAGACTGTGACCT CAAACAGTCACAGCAGAAAATAAATGAGCTCCTTAAACAGAAAGATGTGCTAAATGAGGA TGTTAGAAACCTGACATTAAAAATAGAGCAAGAAACTCAGAAGCGCTGCCTTACACAAAA TGACCTGAAGATGCAAACACAACAGGTTAACACACTAAAAATGTCAGAAAAGCAGTTAAA GCAAGAAAATAACCATCTCATGGAAATGAAAATGAACTTGGAAAAACAAAATGCTGAACT TCGAAAAGAACGTCAGGATGCAGATGGGCAAATGAAAGAGCTCCAGGATCAGCTCGAAGC AGAACAGTATTTCTCAACCCTTTATAAAACACAAGTTAGGGAGCTTAAAGAAGAATGTGA AGAAAAGACCAAACTTGGTAAAGAATTGCAGCAGAAGAAACAGGAATTACAGGATGAACG GGACTCTTTGGCTGCCCAACTGGAGATCACCTTGACCAAAGCAGATTCTGAGCAACTGGC TCGTTCAATTGCTGAAGAACAATATTCTGATTTGGAAAAAGAGAAGATCATGAAAGAGCT GGAGATCAAAGAGATGATGGCTAGACACAAACAGGAACTTACGGAAAAAGATGCTACAAT TGCTTCTCTTGAGGAAACTAATAGGACACTAACTAGTGATGTTGCCAATCTTGCAAATGA GAAAGAAGAATTAAATAACAAATTGAAAGATGTTCAAGAGCAACTGTCAAGATTGAAAGA TGAAGAAATAAGCGCAGCAGCTATTAAAGCACAGTTTGAGAAGCAGCTATTAACAGAAAG AACACTCAAAACTCAAGCTGTGAATAAGTTGGCTGAGATCATGAATCGAAAAGAACCTGT CAAGCGTGGTAATGACACAGATGTGCGGAGAAAAGAGAAGGAGAATAGAAAGCTACATAT GGAGCTTAAATCTGAACGTGAGAAATTGACCCAGCAGATGATCAAGTATCAGAAAGAACT GAATGAAATGCAGGCACAAATAGCTGAAGAGAGCCAGATTCGAATTGAACTGCAGATGAC ATTGGACAGTAAAGACAGTGACATTGAGCAGCTGCGGTCACAACTCCAAGCCTTGCATAT TGGTCTGGATAGTTCCAGTATAGGCAGTGGACCAGGGGATGCTGAGGCAGATGATGGGTT TCCAGAATCAAGATTAGAAGGATGGCTTTCATTGCCTGTACGAAACAACACTAAGAAATT TGGATGGGTTAAAAAGTATGTGATTGTAAGCAGTAAGAAGATTCTTTTCTATGACAGTGA ACAAGATAAAGAACAATCCAATCCTTACATGGTTTTAGATATAGACAAGTTATTTCATGT CCGACCAGTTACACAGACAGATGTGTATAGAGCAGATGCTAAAGAAATTCCAAGGATATT CCAGATTCTGTATGCCAATGAAGGAGAAAGTAAGAAGGAACAAGAATTTCCAGTGGAGCC AGTTGGAGAAAAATCTAATTATATTTGCCACAAGGGACATGAGTTTATTCCTACTCTTTA TCATTTCCCAACCAACTGTGAGGCTTGTATGAAGCCCCTGTGGCACATGTTTAAGCCTCC TCCTGCTTTGGAGTGCCGCCGTTGCCATATTAAGTGTCATAAAGATCATATGGACAAAAA GGAGGAGATTATAGCACCTTGCAAAGTATATTATGATATTTCAACGGCAAAGAATCTGTT ATTACTAGCAAATTCTACAGAAGAGCAGCAGAAGTGGGTTAGTCGGTTGGTGAAAAAGAT ACCTAAAAAGCCCCCAGCTCCAGACCCTTTTGCCCGATCATCTCCTAGAACTTCAATGAA GATACAGCAAAACCAGTCTATTAGACGGCCAAGTCGACAGCTTGCCCCAAACAAACCTAG CTAACTGCCTTCTATGAAAGCAGTCATTATTCAAGGTGATCGTATTCTTCCAGTGAAAAC AAGACTGAAATATGATGGCCCAAAATTTATTAAAAAGCTATATTTTCCTGAGAGACTGAT ACATACACTCATACATATATGTGTTCCCCTTTTCCCTGTAATATAAATTACAAATCTGGG CTCCTTTGAAGCAACAGGTTGAACCAACAATGATTGGTTGATAGACTAAG >OriGene 5' read for NM_004850 unedited
CCTCATTACCCCGCCCGTTGACGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATAT AAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGC CGCGAATTCGGCACGAGGGGACCAGCGGACCGGCGGCGCGAATCTGACTGAGGGGCGGGG ACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCG GGCGGGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGC TAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGGCCGGAGCTGGTGGTTCGGGGGCGGTG CTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGC GGCATGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGG GACGGTGCAGGCGCGAGCCGCCAGAGGAAGCTGGAGGCGCTGATCCGAGACCCTCGCTCC CCCATCAACGTGGAGAGCTTGCTGGATGGCTTAAATTCCTTGGTCCTTGATTTAGATTTT CCTGCTTTGAGGAAAAACAAGAACATAGATAATTTCTTACATAGATATGAGAAAATTGTG AAAAAAATCAGAGGTCTACAGATGAAGGCAGACGACTATGATGTTGTAAAAGTTATTGGC AGAGGTGCTTTTGGTGAAGTGCAGTTGGTTCGTCACAGGCATCGCAGAGGGTTATGCTAT GAAGCTTCTTAGTAGTTTGAATGATAAAAAGACAGATTCTGCCTTTNTTTGGGAGCAAGA GATATATGGCCTTTGCCATAGCCCCTGGGTGGTTCAGCTTNTTTTAGTCTTTCAGACGAT GGTATCTGTACATGTCATG >OriGene 3' read for NM_004850 unedited
TTACTTGNCCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTTTGAGACGGA TCTTGTTCAGCTGGCCAGGCTGAGAGTGCACCAGCTCGATCTTCGCTCACTGCAACACAC CGACTCCTGGGTTCAAGCGATTCTCCTGTCTCAGCTTCCAAACTCCCTGGGATTACCGGC CAGCCTCATTGCGCCCGGCTAATTTTTGCATATTGTTATAGACGGATCTACCCCCTTTTC GGGCATGGCTCGGACTCGAAACTCCATCACCACATGCGATCCTGCCCTCTTGGCTCCTCG AATTGCTACGATTACATGCGAAGGCCTCCATACCTGGCCAGATGATGTTTTTAAATATGA CACCCAACTCTGTGCCTTGATATAAAGAGAGCTGTTCTCTACTTCTGGTGTGTCACTTAA CAATAACTTTTCTCAATCTTTACGCATACCAATGATGCGCATTGTGTGCTTGCCAACAAA CACTCTCTTATCTGGGAACGTGACAACACCGCCAGAATGACCTGCAATGACTGCAACTTT GACAGCGTCTATGACACTAGCAGTCTACTTGAGCGACTTTGAACTCCCGTCTCTCTCATT GCCACCTTTCGCAACCGCTCACTCTTATACAGCGCAACCTGGCTGCATTGTTGCAGCCCA TTTTTAAAAGTTTAACATGCCTTTCCGTTCGCAAAAACCTTTTATATTACTTGGAAAAAT TTAAAATCTTAGATCTTAAAAGGAACACCCAAAGTTCTTACAACCATAATAACCCCTCTG GGGCCACCAGCGAATTCCAAACAAAAAAAATTTCTCCCCCCCCCACCCATACGGGAAACC CGCAACAAACTCCCTTAATTTTTGCCCCACTAAAGCAAATTCCCTTGGAATCCAAAACCT CGGGGACAAAAAAACCAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004850 |
| Insert Size | 6900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004850.3, NP_004841.2 |
| RefSeq Size | 6401 bp |
| RefSeq ORF | 4167 bp |
| Locus ID | 9475 |
| UniProt ID | O75116 |
| Domains | pkinase, HR1, PH, M |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Axon guidance, Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, TGF-beta signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway |
| Gene Summary | The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217764 | ROCK2 (Myc-DDK-tagged)-Human Rho-associated, coiled-coil containing protein kinase 2 (ROCK2) |
CNY 14,248.00 |
|
| RC217764L1 | Lenti ORF clone of Human Rho-associated, coiled-coil containing protein kinase 2 (ROCK2), Myc-DDK-tagged |
CNY 16,648.00 |
|
| RC217764L2 | Lenti ORF clone of Human Rho-associated, coiled-coil containing protein kinase 2 (ROCK2), mGFP tagged |
CNY 15,770.00 |
|
| RC217764L3 | Lenti ORF clone of Human Rho-associated, coiled-coil containing protein kinase 2 (ROCK2), Myc-DDK-tagged |
CNY 16,648.00 |
|
| RC217764L4 | Lenti ORF clone of Human Rho-associated, coiled-coil containing protein kinase 2 (ROCK2), mGFP tagged |
CNY 16,648.00 |
|
| RG217764 | ROCK2 (tGFP-tagged) - Human Rho-associated, coiled-coil containing protein kinase 2 (ROCK2) |
CNY 15,848.00 |
|
| SC323671 | ROCK2 (untagged)-Kinase deficient mutant (K121M) of Human Rho-associated, coiled-coil containing protein kinase 2 (ROCK2) |
CNY 9,504.00 |
