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GUCY2C (NM_004963) Human Untagged Clone
CAT＃: SC117052
GUCY2C (untagged)-Human guanylate cyclase 2C (heat stable enterotoxin receptor) (GUCY2C)
CNY 11,216.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DIAR6; GC-C; GUC2C; MECIL; MUCIL; STAR |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004963 edited
GCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCAGA ATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGCTGGATTCCCTGC CTCCCTAGGAGCCCAACAGAGCAAAGCAAGTGGGCACAAGGAGTATGGTTCTAACGTGAT TGGGGTCATGAAGACGTTGCTGTTGGACTTGGCTTTGTGGTCACTGCTCTTCCAGCCCGG GTGGCTGTCCTTTAGTTCCCAGGTGAGTCAGAACTGCCACAATGGCAGCTATGAAATCAG CGTCCTGATGATGGGCAACTCAGCCTTTGCAGAGCCCCTGAAAAACTTGGAAGATGCGGT GAATGAGGGGCTGGAAATAGTGAGAGGACGTCTGCAAAATGCTGGCCTAAATGTGACTGT GAACGCTACTTTCATGTATTCGGATGGTCTGATTCATAACTCAGGCGACTGCCGGAGTAG CACCTGTGAAGGCCTCGACCTACTCAGGAAAATTTCAAATGCACAACGGATGGGCTGTGT CCTCATAGGGCCCTCATGTACATACTCCACCTTCCAGATGTACCTTGACACAGAATTGAG CTACCCCATGATCTCAGCTGGAAGTTTTGGATTGTCATGTGACTATAAAGAAACCTTAAC CAGGCTGATGTCTCCAGCTAGAAAGTTGATGTACTTCTTGGTTAACTTTTGGAAAACCAA CGATCTGCCCTTCAAAACTTATTCCTGGAGCACTTCGTATGTTTACAAGAATGGTACAGA AACTGAGGACTGTTTCTGGTACCTTAATGCTCTGGAGGCTAGCGTTTCCTATTTCTCCCA CGAACTCGGCTTTAAGGTGGTGTTAAGACAAGATAAGGAGTTTCAGGATATCTTAATGGA CCACAACAGGAAAAGCAATGTGATTATTATGTGTGGTGGTCCAGAGTTCCTCTACAAGCT GAAGGGTGACCGAGCAGTGGCTGAAGACATTGTCATTATTCTAGTGGATCTTTTCAATGA CCAGTACTTGGAGGACAATGTCACAGCCCCTGACTATATGAAAAATGTCCTTGTTCTGAC GCTGTCTCCTGGGAATTCCCTTCTAAATAGCTCTTTCTCCAGGAATCTATCACCAACAAA ACGAGACTTTGCTCTTGCCTATTTGAATGGAATCCTGCTCTTTGGACATATGCTGAAGAT ATTTCTTGAAAATGGAGAAAATATTACCACCCCCAAATTTGCTCATGCTTTCAGGAATCT CACTTTTGAAGGGTATGACGGTCCAGTGACCTTGGATGACTGGGGGGATGTTGACAGTAC CATGGTGCTTCTGTATACCTCTGTGGACACCAAGAAATACAAGGTTCTTTTGACCTATGA TACCCACGTAAATAAGACCTATCCTGTGGATATGAGCCCCACATTCACTTGGAAGAACTC TAAACTTCCTAATGATATTACAGGCCGGGGCCCTCAGATCCTGATGATTGCAGTCTTCAC CCTCACTGGAGCTGTGGTGCTGCTCCTGCTCGTCGCTCTCCTGATGCTCAGAAAATATAG AAAAGATTATGAACTTCGTCAGAAAAAATGGTCCCACATTCCTCCTGAAAATATCTTTCC TCTGGAGACCAATGAGACCAATCATGTTAGCCTCAAGATCGATGATGACAAAAGACGAGA TACAATCCAGAGACTACGACAGTGCAAATACGACAAAAAGCGAGTGATTCTCAAAGATCT CAAGCACAATGATGGTAATTTCACTGAAAAACAGAAGATAGAATTGAACAAGTTGCTTCA GATTGACTATTACAACCTGACCAAGTTCTACGGCACAGTGAAACTTGATACCATGATCTT CGGGGTGATAGAATACTGTGAGAGAGGATCCCTCCGGGAAGTTTTAAATGACACAATTTC CTACCCTGATGGCACATTCATGGATTGGGAGTTTAAGATCTCTGTCTTGTATGACATTGC TAAGGGAATGTCATATCTGCACTCCAGTAAGACAGAAGTCCATGGTCGTCTGAAATCTAC CAACTGCGTAGTGGACAGTAGAATGGTGGTGAAGATCACTGATTTTGGCTGCAATTCCAT TTTACCTCCAAAAAAGGACCTGTGGACAGCTCCAGAGCACCTCCGCCAAGCCAACATCTC TCAGAAAGGAGATGTGTACAGCTATGGGATCATCGCACAGGAGATCATTCTGCGGAAAGA AACCTTCTACACTTTGAGCTGTCGGGACCGGAATGAGAAGATTTTCAGAGTGGAAAATTC CAATGGAATGAAACCCTTCCGCCCAGATTTATTCTTGGAAACAGCAGAGGAAAAAGAGCT AGAAGTGTACCTACTTGTAAAAAACTGTTGGGAGGAAGATCCAGAAAAGAGACCAGATTT CAAAAAAATTGAGACTACACTTGCCAAGATATTTGGACTTTTTCATGACCAAAAAAATGA AAGCTATATGGATACCTTGATCCGACGTCTACAGCTATATTCTCGAAACCTGGAACATCT GGTAGAGGAAAGGACACAGCTGTACAAGGCAGAGAGGGACAGGGCTGACAGACTTAACTT TATGTTGCTTCCAAGGCTAGTGGTAAAGTCTCTGAAGGAGAAAGGCTTTGTGGAGCCGGA ACTATATGAGGAAGTTACAATCTACTTCAGTGACATTGTAGGTTTCACTACTATCTGCAA ATACAGCACCCCCATGGAAGTGGTGGACATGCTTAATGACATCTATAAGAGTTTTGACCA CATTGTTGATCATCATGATGTCTACAAGGTGGAAACCATCGGTGATGCGTACATGGTGGC TAGTGGTTTGCCTAAGAGAAATGGCAATCGGCATGCAATAGACATTGCCAAGATGGCCTT GGAAATCCTCAGCTTCATGGGGACCTTTGAGCTGGAGCATCTTCCTGGCCTCCCAATATG GATTCGCATTGGAGTTCACTCTGGTCCCTGTGCTGCTGGAGTTGTGGGAATCAAGATGCC TCGTTATTGTCTATTTGGAGATACGGTCAACACAGCCTCTAGGATGGAATCCACTGGCCT CCCTTTGAGAATTCACGTGAGTGGCTCCACCATAGCCATCCTGAAGAGAACTGAGTGCCA GTTCCTTTATGAAGTGAGAGGAGAAACATACTTAAAGGGAAGAGGAAATGAGACTACCTA CTGGCTGACTGGGATGAAGGACCAGAAATTCAACCTGCCAACCCCTCCTACTGTGGAGAA TCAACAGCGTTTGCAAGCAGAATTTTCAGACATGATTGCCAACTCTTTACAGAAAAGACA GGCAGCAGGGATAAGAAGCCAAAAACCCAGACGGGTAGCCAGCTATAAAAAAGGCACTCT GGAATACTTGCAGCTGAATACCACAGACAAGGAGAGCACCTATTTTTAAACCTAAATGAG GTATAAGGACTCACACAAATTAAAATACAGCTGCACTGAGGCAGCGACCTCAAGTGTCCT GAAAGCTTACATTTTCCTGAGACCTCAATGAAGCAGAAATGTACTTAGGCTTGGCTGCCC TGTCTGGAACATGGACTTTCTTGCATGAATCAGATGTGTGTTCTCAGTGAAATAACTACC TTCCACTCTGGAACCTTATTCCAGCAGTTGTTCCAGGGAGCTTCTACCTGGAAAAGAAAA GAAATGAATAGACTATCTAGAACTTGAGAAGATTTTATTCTTATTTCATTTATTTTTTGT TTGTTTATTTTTATCGTTTTTGTTTACTGGCTTTCCTTCTGTATTCATAAGATTTTTTAA ATTGTCATAATTATATTTTAAATACCCATCTTCATTAAAGTATATTTAACTCATAATTTT TGCAGAAAATATGCTATATATTAGGCAAGAATAAAAGCTAAAGGTTTCCCAAAAAAAAAA AAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCG GGTGGCATCCCTGTGACCCCTCCCCAGTGCCT >OriGene 5' read for NM_004963 unedited
AATGTTCTNAAGTGNATGGGGTCAGNAANACTTGCTGTTGGNCTTGGCTTTGTGGTCACT GCTCTTCCAGCCCGGGTGGCTGTCCTTTATTCCCAGTGAGTCAGAACTGCCACAATGGCA GCTATGAAATCAGCGTCCTGATGATGGGCAACTCAGCCTTTGCAGAGCCCCTGAAAAACT TGGAAGATGCGGTGAATGAGGGGCTGGAAATAGTGAGAGGACGTCTGCAAAATGCTGGCC TAAATGTGACTGTGAACGCTACTTTCATGTATTCGGATGGTCTGATTCATAACTCAGGCG ACTGCCGGAGTAGCACCTGTGAAGGCCTCGACCTACTCAGGAAAATTTCAAATGCACAAC GGATGGGCTGTGTCCTCATAGGGCCCTCATGTACATACTCCACCTTCCAGATGTACCTTG ACACAGAATTGAGCTACCCCATGATCTCAGCTGGAAGTTTTGGATTGTCATGTGACTATA AAGAAACCTTAACCAGGCTGATGTCTCCAGCTAGAAAGTTGATGTACTTCTTGGTTAACT TTTGGAAAACCAACGATCTGCCCTTCAAAACTTATTCCTGGAGCACTTCGTATGTTTACA AGAATGGTACAGAAACTGAGGACTGTTTCTGGTACCTTAATGCTCTGGAGGCTAGCGTTT CCTATTTCTCCCACGAACTCGGCTTTAAGGTGGTGTTAAGACAAGATAAGGAGTTTCAGG ATATCTTAATGGACCACAACAGGAAAAGNCATGTGATTATTATGTNGTGGTGGGTCCCAG AGTTCCTNNCTACAGCTGAAGGTGACCGAGCAGTGGCTTGAGACATTGTCATTATTCTAG TGGATCTTTTCATGACCAGTACTTGGAGGACATGTCACAGCCCCTGACTATATGAAAAAT GTCCCTTGTTCTGACGCTGTCTCCTTGGAAATTCCTTCTAATAGCTCTTT >OriGene 3' read for NM_004963 unedited
NNAATTCTTGTACGCGCCGCTTTCTANATCGAGTTTTTTTTTTTTTTTTTTTGGGAAACC TTTAGCTTTTATTCTTGCCTAATATATAGCATATTTTCTGCAAAAATTATGAGTTAAATA TACTTTAATGAAGATGGGTATTTAAAATATAATTATGACAATTTAAAAAATCTTATGAAT ACAGAAGGAAAGCCAGTAAACAAAAACGATAAATATAAACAAACAAAAAATAAATGAAAT AAGAATAAAATCTTCTCAAGTTCTAGATAGTCTATTCATTTCTTTTCTTTTCCAGGTAGA AGCTCCCTGGAACAACTGCTGGAATAAGGTTCCAGAGTGGAAGGTAGTTATTTCACTGAG AACACACATCTGATTCATGCAAGAAAGTCCATGTTCCAGACAGGGCAGCCAAGCCTAAGT ACATTTCTGCTTCATTGAGGTCTCAGGAAAATGTAAGCTTTCAGGACACTTGAGGTCGCT GCCTCAGTGCAGCTGTATTTTAATTTGTGTGAGTCCTTATACCTCATTTAGGTTTAAAAA TAGGTGCTCTCCTTGTCTGTGGTATTCAGCTGCAAGTATTCCAGAGTGCCTTTTTTATAG CTGGCTACCCGTCTGGGTTTTTGGCTTCTTATCCCTGCTGCCTGTCTTTTCTGTAAAGAG TTGGCAATCATGTCTGAAAATTCTGCTTGCCAACGCTGTTGATTCTCCACAGTAGGAGGG GTTGGCAGGTTGAAATTCTGGTGCTTTCATCCCATCACCCCGTAGGTGATGCCAGTCCCC TTCCCTTAAATATGTTCCTCCACTCAATTCGTAAAGGACCGGCACTCAGTTCTCTCAGGA GGGTATGGCGGAACCCCTACACTGAATTTCAAAGGGAGGCCAATGGATTCCATCCAAAGG CGAGATAACATGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004963 |
| Insert Size | 3900 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004963.1, NP_004954.1 |
| RefSeq Size | 3745 bp |
| RefSeq ORF | 3222 bp |
| Locus ID | 2984 |
| UniProt ID | P25092 |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Purine metabolism |
| Gene Summary | This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213901 | GUCY2C (Myc-DDK-tagged)-Human guanylate cyclase 2C (heat stable enterotoxin receptor) (GUCY2C) |
CNY 11,208.00 |
|
| RC213901L1 | Lenti ORF clone of Human guanylate cyclase 2C (heat stable enterotoxin receptor) (GUCY2C), Myc-DDK-tagged |
CNY 13,608.00 |
|
| RC213901L2 | Lenti ORF clone of Human guanylate cyclase 2C (heat stable enterotoxin receptor) (GUCY2C), mGFP tagged |
CNY 13,608.00 |
|
| RC213901L3 | Lenti ORF clone of Human guanylate cyclase 2C (heat stable enterotoxin receptor) (GUCY2C), Myc-DDK-tagged |
CNY 13,608.00 |
|
| RC213901L4 | Lenti ORF clone of Human guanylate cyclase 2C (heat stable enterotoxin receptor) (GUCY2C), mGFP tagged |
CNY 13,608.00 |
|
| RG213901 | GUCY2C (tGFP-tagged) - Human guanylate cyclase 2C (heat stable enterotoxin receptor) (GUCY2C) |
CNY 12,808.00 |
