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CTNS (NM_004937) Human Untagged Clone
CAT＃: SC117040
CTNS (untagged)-Human cystinosis, nephropathic (CTNS), transcript variant 2
CNY 3,656.00
CNY 5,990.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CTNS-LSB; PQLC4; SLC66A4 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117040 sequence for NM_004937 edited (data generated by NextGen Sequencing)
ATGATAAGGAATTGGCTGACTATTTTTATCCTTTTTCCCCTGAAGCTCGTAGAGAAATGT GAGTCAAGCGTCAGCCTCACTGTTCCTCCTGTCGTAAAGCTGGAGAACGGCAGCTCGACC AACGTCAGCCTCACCCTGCGGCCACCATTAAATGCAACCCTGGTGATCACTTTTGAAATC ACATTTCGTTCCAAAAATATTACTATCCTTGAGCTCCCCGATGAAGTTGTGGTGCCTCCT GGAGTGACAAACTCCTCTTTTCAAGTGACATCTCAAAATGTTGGACAACTTACTGTTTAT CTACATGGAAATCACTCCAATCAGACCGGCCCGAGGATACGCTTTCTTGTGATCCGCAGC AGCGCCATTAGCATCATAAACCAGGTGATTGGCTGGATCTACTTTGTGGCCTGGTCCATC TCCTTCTACCCTCAGGTGATCATGAATTGGAGGCGGAAAAGTGTCATTGGTCTGAGCTTC GACTTCGTGGCTCTGAACCTGACGGGCTTCGTGGCCTACAGTGTATTCAACATCGGCCTC CTCTGGGTGCCCTACATCAAGGAGCAGTTTCTCCTCAAATACCCCAACGGAGTGAACCCC GTGAACAGCAACGACGTCTTCTTCAGCCTGCACGCGGTTGTCCTCACGCTGATCATCATC GTGCAGTGCTGCCTGTATGAGCGCGGTGGCCAGCGCGTGTCCTGGCCTGCCATCGGCTTC CTGGTGCTCGCGTGGCTCTTCGCATTTGTCACCATGATCGTGGCTGCAGTGGGAGTGATC ACGTGGCTGCAGTTTCTCTTCTGCTTCTCCTACATCAAGCTCGCAGTCACGCTGGTCAAG TATTTTCCACAGGCCTACATGAACTTTTACTACAAAAGCACTGAGGGCTGGAGCATTGGC AACGTGCTCCTGGACTTCACCGGGGGCAGCTTCAGCCTCCTGCAGATGTTCCTCCAGTCC TACAACAACGACCAGTGGACGCTGATCTTCGGAGACCCAACCAAGTTTGGACTCGGGGTC TTCTCCATCGTCTTCGACGTCGTCTTCTTCATCCAGCACTTCTGTTTGTACAGAAAGAGA CCGGGGTATGACCAGCTGAACTAG Clone variation with respect to NM_004937.2 779 c=>t >OriGene 5' read for NM_004937 unedited
TGGAGCACCAGGGAGGCGGTGCATTCCTGACCGGCACCTGGCGAGGCTCATGCGTCCCGT GAGGGCGGTTCCTCGAGCCTGGGGGCGCTCAGATTGCTTTGGAGACGCTGAGAGAACCTT TGCGAGAGCGCCGGTTGACGTGCGGAGTGCGGGGCTCCGGGGGACTGAGCAGCACGAGAC CCCATCCTCCCCTCCGGGTTTTCACACTGGGCGAAGGGAGGACTCCTGAGCTCTGCCTCT TCCAGTAACATTGAGGATTACTGTGTTTTGTGAGAGCTCGCTAGGCGCCCTAAGCAACAG AGTTCTGAGAAATCGAGAAACATGATAAGGAATTGGCTGACTATTTTTATCCTTTTTCCC CTGAAGCTCGTAGAGAAATGTGAGTCAAGCGTCAGCCTCACTGTTCCTCCTGTCGTAAAG CTGGAGAACGGCAGCTCGACCAACGTCAGCCTCACCCTGCGGCCACCATTAAATGCAACC CTGGTGATCACTTTTGAAATCACATTTCGTTCCAAAAATATTACTATCCTTGAGCTCCCC GATGAAGTTGTGGTGCCTCCTGGAGTGACAAACTCCTCTTTTCAAGTGACATCTCAAAAT GTTGGACAACTTACTGTTTATCTACATGGAAATCACTCCAATCAGACCGGCCCGAGGATA CGCTTTCTTGTGATCCGCAGCAGCGCCATTAGCATCATANACCAGGTGATTGGCTGGATC TACTTTGTGGCCTGGTCCATCTNCTTCTACCCTCAGGTGATCATGAATTTGGAGCNGAAA GTGTCATTGGTCTGAGCTTCGACTTCGTGGCTCTGAACCTGACCGGCTTCGTGGCCTACA GTGTATTNCACATCGGCCTCCTCTGGGTAGCCTACTCAAGGAGCAGTTCCTCCTAAATAC CCAAN >OriGene 3' read for NM_004937 unedited
TTTTTAGAAAGGAAAGCGAGTAGGTTTTAATTCAAAAACAGGCCCCTCGCGTTGATCTCG TAAAAGGAAACTCAGGGGACTGACAAGCTCAAGTCATGTATGAGGCACGTCCTGGGACCC CCACCCCTCCTGCCATAGGAAGGACAGCTTTGGGCAAAGGGAAGGAGGTTTGAAATCAGG GTTGGCCCCATACAAATTGGGTGAGGGGGTCTCAAGTACAAATACTTATCTGAGGCTCCT GAACAGGCCAAAAATTGGTGAGTCTCAAGTAGGTGTCTGGGGAAAAAGAGGGAAGGGGCC TGCCCTCGCTCCAGGGGAGCTGGTCGCCGTTTGGCAGGCCTAACAAACCTCTAAGGCACA AACTGGTAGCAGGAAAAAGCTATGTCCTGTACTCCAAATGCTGGGTAAGGAGCAGCTGGA TGTGCTCAAATGGGGCTCTTCTGAAAAGGTGGAGGTAGGAAAAAGGGCAAAAAAGAGTAA GCCACTTCCAAACGTCCCTCCAAAAAATCTGAAAGGAGTTACTATGCTAATGCGCTGGGC ATGAATCCAATTCAAAACCAATCGTGGTGGGCCCCTCATGGCTAAAAAATACTCTGGGTA GGGGCTTGGCTGTTACTGCAGTCACGGACGCTGAGTTATGTACAGAGAGTACGTCAGGGA TAGTGGCCTTAAGAAGAAGAGCCCCATGGCCTAACCCCAAAGTCCTAGCCCGTCCACCAG CACCTNTTGAGTTCACTGGCCACGCACCCGGCTGTTTGATCTTTTGGAATGCACCGGTGG CAACAAAGTGCCCTTGGCTCACCCGGTTGAAAGGTAGCCCTTAAGCTGCTGCAAAACGCT GGGGNNTTGGGGGCAAAGCCCTTTGTTGAAACCTGCTGGCCATCCTGNCTGAAAACGGTG CCAAACCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004937 |
| Insert Size | 2550 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004937.1, NP_004928.1 |
| RefSeq Size | 2611 bp |
| RefSeq ORF | 1104 bp |
| Locus ID | 1497 |
| UniProt ID | O60931 |
| Domains | CTNS |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Lysosome |
| Gene Summary | This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009] Transcript Variant: This variant (2) differs in the 5' UTR, 3' UTR and 3' coding region, compared to variant 1, resulting in an isoform (2) with a distinct and shorter C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213151 | CTNS (Myc-DDK-tagged)-Human cystinosis, nephropathic (CTNS), transcript variant 2 |
CNY 3,656.00 |
|
| RC213151L3 | Lenti ORF clone of Human cystinosis, nephropathic (CTNS), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC213151L4 | Lenti ORF clone of Human cystinosis, nephropathic (CTNS), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG213151 | CTNS (tGFP-tagged) - Human cystinosis, nephropathic (CTNS), transcript variant 2 |
CNY 5,256.00 |
