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PI 3 Kinase p85 beta (PIK3R2) (NM_005027) Human Untagged Clone
CAT＃: SC116980
PIK3R2 (untagged)-Human phosphoinositide-3-kinase, regulatory subunit 2 (beta) (PIK3R2)
CNY 8,008.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MPPH; MPPH1; p85; p85-BETA; P85B |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_005027 edited
ATGGCGGGCCCTGAGGGCTTCCAGTACCGCGCTCTGTACCCGTTCCGCCGGGAGCGGCCG GAGGACCTGGAGCTGCTGCCCGGCGACGTGCTGGTAGTGAGCCGGGCGGCCTTGCAGGCG CTGGGCGTGGCCGAGGGTGGCGAGCGCTGCCCACAGAGCGTGGGCTGGATGCCCGGCCTC AACGAGCGCACACGGCAGCGAGGTGACTTCCCTGGCACCTATGTGGAGTTCCTGGGGCCC GTGGCCCTGGCCCGGCCCGGCCCTCGCCCACGGGGCCCCCGCCCACTGCCCGCCAGGCCC CGTGATGGGGCCCCTGAGCCAGGCCTCACACTCCCCGACTTGCCCGAGCAGTTCTCCCCA CCTGATGTGGCTCCCCCTCTTCTGGTGAAGCTTGTGGAGGCCATTGAAAGGACAGGGCTG GACAGCGAATCTCACTACCGCCCGGAGCTGCCCGCACCGCGTACAGACTGGTCCCTGAGC GACGTGGATCAGTGGGACACGGCAGCCCTGGCTGACGGCATTAAGAGCTTCCTGCTGGCA CTGCCCGCGCCGCTCGTGACCCCCGAGGCCTCGGCCGAGGCGCGCCGGGCCCTGCGGGAG GCCGCGGGGCCCGTGGGGCCGGCGCTGGAGCCACCGACGCTGCCGCTGCACCGCGCGCTC ACGCTGCGCTTCCTGCTCCAGCACCTGGGCCGCGTGGCCCGCCGCGCCCCGGCCCTGGGT CCCGCGGTCCGGGCCCTGGGCGCCACCTTTGGGCCGCTGCTGCTGCGCGCGCCGCCGCCG CCGTCCTCGCCGCCGCCAGGGGGCGCTCCCGACGGGAGTGAGCCCAGCCCTGACTTCCCG GCGCTGCTGGTGGAGAAGCTGCTTCAGGAACACTTGGAAGAGCAGGAGGTTGCGCCCCCA GCGCTGCCGCCTAAACCCCCCAAGGCAAAGCCGGCCCCCACAGTCCTGGCCAATGGAGGG AGCCCACCCTCCCTGCAGGATGCTGAGTGGTACTGGGGGGACATTTCAAGGGAGGAGGTG AACGAGAAACTCCGGGACACTCCCGATGGCACCTTCCTAGTCCGAGATGCTTCTAGCAAG ATCCAGGGCGAGTACACGCTGACCCTCAGGAAAGGCGGGAACAATAAGCTGATCAAGGTC TTCCACCGAGATGGGCACTATGGCTTCTCAGAGCCACTCACCTTCTGCTCCGTTGTGGAC CTCATCAATCACTACCGCCACGAGTCTCTGGCCCAGTACAATGCCAAGCTGGACACACGG CTCCTCTACCCTGTGTCCAAATACCAGCAGGACCAGATTGTCAAGGAGGACAGCGTGGAG GCAGTGGGCGCCCAGCTTAAGGTCTATCACCAGCAGTACCAGGACAAGAGCCGCGAGTAT GACCAGCTTTATGAAGAGTACACACGGACCTCCCAGGAGCTGCAGATGAAGCGTACTGCA ATTGAGGCCTTCAATGAGACTATCAAGATCTTTGAAGAGCAGGGCCAGACTCAAGAGAAA TGCAGCAAGGAATACCTGGAGCGCTTCCGGCGTGAGGGCAACGAGAAAGAGATGCAAAGG ATCCTGCTGAACTCCGAGCGGCTCAAGTCCCGCATTGCCGAGATCCATGAGAGCCGCACG AAGCTGGAGCAGCAGCTGCGGGCCCAGGCCTCGGACAACAGAGAGATCGACAAGCGCATG AACAGCCTCAAGCCGGACCTCATGCAGCTGCGCAAGATCCGAGACCAGTACCTCGTGTGG CTCACCCAGAAAGGCGCCCGGCAGAAGAAAATCAACGAGTGGCTGGGGATTAAAAATGAG ACTGAGGACCAGTACGCACTCATGGAGGACGAGGACGATCTCCCGCACCACGAGGAACGC ACTTGGTACGTGGGCAAGATCAACCGCACGCAGGCAGAGGAGATGCTGAGTGGCAAGCGG GATGGCACCTTCCTCATCCGCGAGAGCAGCCAGCGGGGCTGCTACGCCTGCTCCGTGGTA GTGGACGGCGACACCAAGCACTGCGTCATCTACCGCACGGCCACCGGCTTCGGCTTCGCG GAGCCCTACAACCTGTACGGGTCGCTGAAGGAGCTGGTGCTGCACTACCAGCACGCCTCG CTGGTGCAGCACAACGACGCGCTCACCGTCACCCTGGCGCACCCAGTGCGCGCCCCGGGC CCCGGCCCGCCGCCTGCCGCCCGCTGA >OriGene 5' read for NM_005027 unedited
TAACCCCCGCCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG CAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC GAATTCGGACGAGGCAATGGCCCAGTGACCTGACACCACACCACCAACTCCCTCCCACCA GCTGACGAATGGTGGACCCAGTGACGAGTGGCCCTTGTAAGGGTCATGGAATAATTTGAA GCGAGGCATGAGCGGCCCCTGTGGTCGCCTGTGACTGCTGGAGATAGAGGTCCCAGCACC CCAAGCCAACCCAGCGGACCCTCCCAGCCCTGCTTCAACCAATGGGGCCAGTGGGGCTCC AAGCAGCCACCTAACCATCCAGACCCCACCCCACTCACGCGGCCATGGCGGGCCCTGAGG GCTTCCAGTACCGCGCTCTGTACCCGTTCCGCCGGGAGCGGCCGGAGGACCTGGAGCTGC TGCCCGGCGACGTGCTGGTAGTGAGCCGGGCGGCCTTGCAGGCGCTGGGCGTGGCCGAGG GTGGCGAGCGCTGCCCACAGAGCGTGGGCTGGATGCCCGGCCTCAACGAGCGCACACGGC AGCGAGGTGACTTNCCTGGCACCTATGTGGAGTTNCTGGGGCCCGTGGCCCTGGCCCGGC CCGCCCTCGCCCACGGNNGCCCCGCCACTGCCCGCCAGGCCCCGTGATGGGGCCCCTGAG CCAGGCCTACACTTCCCGACTTGCCCGACAGTTCTCCCCACTGATGTGGCTCCCCTCTTC TGTGAAGCTGTTGAGGCCCATGAAGGACAGGGCTGGACAGCGAATCTCACTACGCCCGGA CTGCCGCACGCGTACGACTGGTCCTGACGAGTGGATCGTGGGACACGCAGCCTGCCTGAC GCATTAGAGCTTCTGCTGCACTGCCGCGCCGTCGGACCCCGAGCTCGCN >OriGene 3' read for NM_005027 unedited
GAACTACTATGTACGTGGCCGCGTTCTATGATCGGTTTTTTTTTTTTTTTTTTGACGTTT GATGTTTTATATCATATCAATAACAACGTACCGTACAAAACCTGCCTCCCAGCTCGTGGG GCAGGCAGTGTGGTGGCCAAGGGCAGCGTATAAAACCAGGGCTCTTGTCCCAAAAGAGGA GAGGAAAGAGGGTTTTGCAGTCAAGGAAAAACAGAATCAAAACCCAACATGATCGAAGAG AAGCCCTGAATCTGCATCAGAGGGAGGGGCCGTGGGCAGTGTCGCAACTTGGCCACTGCG GCGGCACCAGTACGGGGAGCTGTGATTCCTAAGAGGGGTTGGGGCCAGCTCACAAGTTTA TTTATTTATTTTTTTGAGACGGAGGAGTCTCCCTCTGTTACCCAAGCTGGGAGTGCANTG GCACGATCTCTGCTCACTGCAACCTCCATCTCCTGGGTTCAAGAGATTCTCACGCCTCAG CCTCCCAAGTAGCTGGGATTACAGGCGGCCGCCACCACGCCCGGCTAATTTTTGTATTTT AGTAGATGCGGGGTTTTGCCATTTTGGCCAAATTGGCCTTCAACTCCCGACCTTCAAAGA TCCGCCCGTCTTGGCCTCCCCAAGTGCTGGGATTACAGGCATGAACCACCGTGCCTGGCC TGCGAGTTTAATTTTTTTTTCGGGGTGGGGTGAACTTTTCTGCACCGGCCCCTTTGGGGG GTAACCCGGTGGCGGGTTTTACCTTGGGGTTTGGAGGGGAATTTGGGTTCTGTGGGGCGG GTCCCCCCCGGCCCCCATGGTACCGGCCCGGGTTTTTTGGAACCACAAAATTGAATTTCC TTTCTGGCCCTGCCCCAGGTCTATGGGCTTAAAAATAAGGGGCCCCACA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005027 |
| Insert Size | 3500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005027.2, NP_005018.1 |
| RefSeq Size | 3953 bp |
| RefSeq ORF | 2187 bp |
| Locus ID | 5296 |
| UniProt ID | O00459 |
| Domains | RhoGAP, SH2, SH3 |
| Protein Families | Druggable Genome |
| Protein Pathways | Acute myeloid leukemia, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Glioma, Insulin signaling pathway, Jak-STAT signaling pathway, Leukocyte transendothelial migration, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway |
| Gene Summary | Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Three transcript variants, one protein coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Apr 2019] Transcript Variant: This variant (1) represents the protein-coding variant. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209834 | PIK3R2 (Myc-DDK-tagged)-Human phosphoinositide-3-kinase, regulatory subunit 2 (beta) (PIK3R2) |
CNY 8,000.00 |
|
| RC209834L1 | Lenti-ORF clone of PIK3R2 (Myc-DDK-tagged)-Human phosphoinositide-3-kinase, regulatory subunit 2 (beta) (PIK3R2) |
CNY 10,400.00 |
|
| RC209834L2 | Lenti-ORF clone of PIK3R2 (mGFP-tagged)-Human phosphoinositide-3-kinase, regulatory subunit 2 (beta) (PIK3R2) |
CNY 7,700.00 |
|
| RC209834L3 | Lenti-ORF clone of PIK3R2 (Myc-DDK-tagged)-Human phosphoinositide-3-kinase, regulatory subunit 2 (beta) (PIK3R2) |
CNY 7,700.00 |
|
| RC209834L4 | Lenti-ORF clone of PIK3R2 (mGFP-tagged)-Human phosphoinositide-3-kinase, regulatory subunit 2 (beta) (PIK3R2) |
CNY 7,700.00 |
|
| RG209834 | PIK3R2 (tGFP-tagged) - Human phosphoinositide-3-kinase, regulatory subunit 2 (beta) (PIK3R2) |
CNY 9,600.00 |
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