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APLP1 (NM_005166) Human Untagged Clone
CAT＃: SC116888
APLP1 (untagged)-Human amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 2
CNY 4,848.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APLP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC116888 sequence for NM_005166 edited (data generated by NextGen Sequencing)
ATGGGGCCCGCCAGCCCCGCTGCTCGCGGTCTAAGTCGCCGCCCGGGCCAGCCGCCGCTG CCGCTGCTGCTGCCACTATTGCTGCTGCTTCTGCGCGCGCAGCCCGCCATCGGGAGCCTG GCCGGTGGGAGCCCCGGCGCGGCCGAGGCCCCGGGGTCGGCCCAGGTGGCTGGACTATGC GGGCGCCTAACCCTTCACCGGGACCTGCGCACCGGCCGCTGGGAACCAGACCCACAGCGC TCTCGACGCTGTCTCCGGGACCCGCAGCGCGTGCTGGAGTACTGCAGACAGATGTACCCG GAGCTGCAGATTGCACGTGTGGAGCAGGCTACGCAGGCCATCCCCATGGAGCGCTGGTGC GGGGGTTCCCGGAGCGGCAGCTGCGCCCACCCCCACCACCAGGTTGTGCCCTTCCGCTGC CTGCCTGGTGAATTTGTGAGTGAGGCCCTGCTGGTGCCTGAAGGCTGCCGGTTCTTGCAC CAGGAGCGCATGGACCAATGTGAGAGTTCAACCCGGAGGCATCAGGAGGCACAGGAGGCC TGCAGCTCCCAGGGCCTCATCCTGCACGGCTCGGGCATGCTCTTACCCTGTGGCTCGGAT CGGTTCCGTGGTGTGGAGTATGTGTGCTGTCCCCCTCCAGGGACCCCCGACCCATCTGGG ACAGCAGTTGGTGACCCCTCCACCCGGTCCTGGCCCCCGGGGAGCAGAGTAGAGGGGGCT GAGGACGAGGAAGAGGAGGAATCCTTCCCACAGCCAGTAGATGATTACTTCGTGGAGCCT CCGCAGGCTGAAGAGGAAGAGGAAACGGTCCCACCCCCAAGCTCCCATACACTTGCAGTG GTCGGCAAAGTCACTCCCACCCCGAGGCCCACAGACGGTGTGGATATTTACTTTGGCATG CCTGGGGAAATCAGTGAGCACGAGGGGTTCCTGAGGGCCAAGATGGACCTGGAGGAGCGT AGGATGCGCCAGATTAATGAGGTGATGCGTGAATGGGCCATGGCAGACAACCAGTCCAAG AACCTGCCTAAAGCCGACAGACAGGCCCTGAATGAGCACTTCCAGTCCATTCTGCAGACT CTGGAGGAGCAGGTGTCTGGTGAGCGACAGCGCCTGGTGGAAACCCACGCCACCCGCGTC ATCGCCCTTATCAACGACCAGCGCCGGGCTGCCTTGGAGGGCTTCCTGGCAGCCCTGCAG GCAGATCCGCCTCAGGCGGAGCGTGTCCTGTTGGCCCTGCGGCGCTACCTGCGTGCGGAG CAGAAGGAACAGAGGCACACGCTGCGCCACTACCAGCATGTGGCCGCCGTGGATCCCGAG AAGGCACAGCAGATGCGCTTCCAGGTGCATACCCACCTTCAAGTGATTGAGGAGAGGGTG AATCAGAGCCTGGGCCTGCTTGACCAGAACCCCCACCTGGCTCAGGAGCTGCGGCCCCAA ATCCAGGAACTCCTCCACTCTGAACACCTGGGTCCCAGTGAATTGGAAGCCCCTGCCCCT GGGGGCAGCAGCGAGGACAAGGGTGGGCTGCAGCCTCCAGATTCCAAGGATGACACCCCC ATGACCCTTCCAAAAGGGTCCACAGAACAAGATGCTGCATCCCCTGAGAAAGAGAAGATG AACCCGCTGGAACAGTATGAGCGAAAGGTGAATGCGTCTGTTCCAAGGGGTTTCCCTTTC CACTCATCGGAGATTCAGAGGGATGAGCTGGCACCAGCTGGGACAGGGGTGTCCCGTGAG GCTGTGTCGGGTCTGCTGATCATGGGAGCGGGCGGAGGCTCCCTCATCGTCCTCTCCATG CTGCTCCTGCGCAGGAAGAAGCCCTACGGGGCTATCAGCCATGGCGTGGTGGAGGTGGAC CCCATGCTGACCCTGGAGGAGCAGCAGCTCCGCGAACTGCAGCGGCACGGCTATGAGAAC CCCACTTACCGCTTCCTGGAGGAACGACCCTGA Clone variation with respect to NM_005166.3 >OriGene 5' read for NM_005166 unedited
CCGCACTTCTATAGGCGGCCGCGCAATTCGCACGAGGCATGGGGCCCGCCAGCCCCGCTG CTCGCGGTCTAAGGGGGCGCCCGGGCCAGCCGCCGCTGCCGCTGCTGCTGCCACTATTGC TGCTGCTTCTGCGCGCGCAGCCCGCCATCGGGAGCCTGGCCGGTGGGAGCCCCGGCGCGG CCGAGGCCCCGGGGTCGGCCCAGGTGGCTGGACTATGCGGGCGCCTAACCCTTCACCGGG ACCTGCGCACCGGCCGCTGGGAACCAGACCCACAGCGCTCTCGACGCTGTCTCCGGGACC CGCAGCGCGTGCTGGAGTACTGCAGACAGATGTACCCGGAGCTGCAGATTGCACGTGTGG AGCAGGCTACGCAGGCCATCCCCATGGAGCGCTGGTGCGGGGGTTCCCGGAGCGGCAGCT GCGCCCACCCCCACCACCAGGTTGTGCCCTTCCGCTGCCTGCCTGGTGAATTTGTGAGTG AGGCCCTGCTGGTGCCTGAAGGCTGCCGGTTCTTGCACCAGGAGCGCATGGACCAATGTG AGAGTTCAACCCGGAGGCATCAGGAGGCACAGGAGGCCTGCAGCTCCCAGGGCCTCATCC TGCACGGCTCGGGCATGCTCTTACCCTGTGGCTCGGATCGGTTCCGTGGTGTGGAGTATG TGTGCTGTCCCCCTCCAGGGACCCCCGACCCATCTGGGACAGCAGTTGGTGACCCCTCCA CCCGTCCTGGCCCCCGGNGAGCANAGTANAGGGGGCTGANGACGANGAAGAGGAGAATCC TTCCACAGCCAGTAGATGATACTTCGTGGAGCCTCCGCAGCTGAAAAGAGAGGGNAAACG GTCCCACCCCAGCTCCATACCTNGCAGTGGTCGGNAAGTCACTCCACCCGAGCCACAGAA GGGGGTGAATATTACTTTGGCTGCCTGGGAATCATGGACCCAGGGGTCCTGAGGGCANAT GGACTNAAGGACCTAGAGCCCT >OriGene 3' read for NM_005166 unedited
ACTTCCAGGGCCGGNAAAGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTC AGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGT AGGGAAGAGGACTTTATTGGGATGTTAGTAGGGAAACATGAGAGGGTGAATTCCAGGGAA TAGACACTAGGACCAAGGTGGCGGTCACCTTAAAGAGCCATAAATAAACTTAAAAAATAA ATTAAGGTGAGGAGGTGCCACGTGGGGAGGCTGCTGGGACTATCTGGGAATTCTTAGGGA TGGAATTTTGGAATTGGAAAGGGGAAATAAGAATTTCCAGCCGTCTCACAAAAGGGTGTG AAATGATCACTTCAAGACTCCCTGCTGCCCTAGGCTGGGAGTTGGGGTTCTGGGGCTCCA GGAAGAGGGGAGGTCTGGGCTCGGCTGAAGGGGTGAAGGGGGCCGGGTCAGGGTCGTTCC TCCAGGAAGCGGTAAGTGGGGTTCTCATAGCCGTGCCGCTGCAGTTCGCGGAGCTGCTGC TCCTCCAGGGTCAGCATGGGGTCCACCTCCACCACGCCATGGCTGATAGCCCCGTNAGGC TTCTTCCTGCGCAGGAGCAGCATGGAGAGGACGATGAGGGAGCCTCCGCCCGCTCCCATG ATCAGCAGACCCGACACAGCCTCACGGGACACCCCTGTCCCAGCTGGTGCCAGCTCATCC CTCTGAATCTNCGATGAGTGGGAAAGGGAAACCCCTTGGAACAGACGCATTCACCTTTCG CTATACTGGTCCAGCGGGTTCATCTTCTCTTCTCAGGGGATGCGCATCTTGTTCTGTGAC CTTTNGGAGGTAATNGGGGGGGGGTCATCTTGATCTGGAGCTGCACCCACCTTGNCTCCT GTGCCCAGGGGGAGGGGCTTCATACTGAACCAGTGTGTTAANGGAAAGGGAGCTTTGGTT TTTTGGGCGATCTCACACAGNNGNNGGNNTTNT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005166 |
| Insert Size | 2440 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005166.3, NP_005157.1 |
| RefSeq Size | 2447 bp |
| RefSeq ORF | 1953 bp |
| Locus ID | 333 |
| UniProt ID | P51693 |
| Domains | A4_EXTRA |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215282 | APLP1 (Myc-DDK-tagged)-Human amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 2 |
CNY 4,840.00 |
|
| RC215282L1 | Lenti ORF clone of Human amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 2, Myc-DDK-tagged |
CNY 7,240.00 |
|
| RC215282L2 | Lenti ORF clone of Human amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 2, mGFP tagged |
CNY 6,460.00 |
|
| RC215282L3 | Lenti ORF clone of Human amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 2, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC215282L4 | Lenti ORF clone of Human amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 2, mGFP tagged |
CNY 6,460.00 |
|
| RG215282 | APLP1 (tGFP-tagged) - Human amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 2 |
CNY 6,440.00 |
