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c-Myb (MYB) (NM_005375) Human Untagged Clone
CAT＃: SC116779
MYB (untagged)-Human v-myb myeloblastosis viral oncogene homolog (avian) (MYB), transcript variant 2
CNY 7,160.00
| Cited in 6 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | c-myb; c-myb_CDS; Cmyb; efg |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_005375, the custom clone sequence may differ by one or more nucleotides
ATGGCCCGAAGACCCCGGCACAGCATATATAGCAGTGACGAGGATGATGAGGACTTTGAGATGTGTGACC ATGACTATGATGGGCTGCTTCCCAAGTCTGGAAAGCGTCACTTGGGGAAAACAAGGTGGACCCGGGAAGA GGATGAAAAACTGAAGAAGCTGGTGGAACAGAATGGAACAGATGACTGGAAAGTTATTGCCAATTATCTC CCGAATCGAACAGATGTGCAGTGCCAGCACCGATGGCAGAAAGTACTAAACCCTGAGCTCATCAAGGGTC CTTGGACCAAAGAAGAAGATCAGAGAGTGATAGAGCTTGTACAGAAATACGGTCCGAAACGTTGGTCTGT TATTGCCAAGCACTTAAAGGGGAGAATTGGAAAACAATGTAGGGAGAGGTGGCATAACCACTTGAATCCA GAAGTTAAGAAAACCTCCTGGACAGAAGAGGAAGACAGAATTATTTACCAGGCACACAAGAGACTGGGGA ACAGATGGGCAGAAATCGCAAAGCTACTGCCTGGACGAACTGATAATGCTATCAAGAACCACTGGAATTC TACAATGCGTCGGAAGGTCGAACAGGAAGGTTATCTGCAGGAGTCTTCAAAAGCCAGCCAGCCAGCAGTG GCCACAAGCTTCCAGAAGAACAGTCATTTGATGGGTTTTGCTCAGGCTCCGCCTACAGCTCAACTCCCTG CCACTGGCCAGCCCACTGTTAACAACGACTATTCCTATTACCACATTTCTGAAGCACAAAATGTCTCCAG TCATGTTCCATACCCTGTAGCGTTACATGTAAATATAGTCAATGTCCCTCAGCCAGCTGCCGCAGCCATT CAGAGACACTATAATGATGAAGACCCTGAGAAGGAAAAGCGAATAAAGGAATTAGAATTGCTCCTAATGT CAACCGAGAATGAGCTAAAAGGACAGCAGGTGCTACCAACACAGAACCACACATGCAGCTACCCCGGGTG GCACAGCACCACCATTGCCGACCACACCAGACCTCATGGAGACAGTGCACCTGTTTCCTGTTTGGGAGAA CACCACTCCACTCCATCTCTGCCAGCGGATCCTGGCTCCCTACCTGAAGAAAGCGCCTCGCCAGCAAGGT GCATGATCGTCCACCAGGGCACCATTCTGGATAATGTTAAGAACCTCTTAGAATTTGCAGAAACACTCCA ATTTATAGATTCTTTCTTAAACACTTCCAGTAACCATGAAAACTCAGACTTGGAAATGCCTTCTTTAACT TCCACCCCCCTCATTGGTCACAAATTGACTGTTACAACACCATTTCATAGAGACCAGACTGTGAAAACTC AAAAGGAAAATACTGTTTTTAGAACCCCAGCTATCAAAAGGTCAATCTTAGAAAGCTCTCCAAGAACTCC TACACCATTCAAACATGCACTTGCAGCTCAAGAAATTAAATACGGTCCCCTGAAGATGCTACCTCAGACA CCCTCTCATCTAGTAGAAGATCTGCAGGATGTGATCAAACAGGAATCTGATGAATCTGGAATTGTTGCTG AGTTTCAAGAAAATGGACCACCCTTACTGAAGAAAATCAAACAAGAGGTGGAATCTCCAACTGATAAATC AGGAAACTTCTTCTGCTCACACCACTGGGAAGGGGACAGTCTGAATACCCAACTGTTCACGCAGACCTCG CCTGTGGCAGATGCACCGAATATTCTTACAAGCTCCGTTTTAATGGCACCAGCATCAGAAGATGAAGACA ATGTTCTCAAAGCATTTACAGTACCTAAAAACAGGTCCCTGGCGAGCCCCTTGCAGCCTTGTAGCAGTAC CTGGGAACCTGCATCCTGTGGAAAGATGGAGGAGCAGATGACATCTTCCAGTCAAGCTCGTAAATACGTG AATGCATTCTCAGCCCGGACGCTGGTCATGTGA >OriGene 5' read for NM_005375 unedited
GGTTAAAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGCAGGCAGG CGGCGGGCAGCGGGAGGCGGCAGCCCGGTGCGGTCCCCGCGGCTCTCGGCGGAGCCCCGC GCCCGCCGCGCCATGGCCCGAAGACCCCGGCACAGCATATATAGCAGCGACGAGGATGAT GAGGACTTTGAGATGTGTGACCATGACTATGATGGGCTGCTTCCCAAGTCTGGAAAGCGT CACTTGGGGAAAACAAGGTGGACCCGGGAAGAGGATGAAAAACTGAAGAAGCTGGTGGAA CAGAATGGAACAGATGACTGGAAAGTTATTGCCAATTATCTCCCGAATCGAACAGATGTG CAGTGCCAGCACCGATGGCAGAAAGTACTAAACCCTGAGCTCATCAAGGGTCCTTGGACC AAAGAAGAAGATCAGAGAGTGATAGAGCTTGTACAGAAATACGGTCCGAAACCGTTGGTC TGTTATTGCCCAAGCCACCTTAAAGGGGAGAATTGGAAAACAATGTATGGAGAGGTGGCA TAACCACTTGAATCCACAAGTTAAGAAAACCTCCTGGACCGAACAGGAAGACAGAATTAT TTACCAGGCACACCAGAGACTGGGGGAACAGAATGGCCACACATCGCAAAGCTACTGCCT GGCACGAACTGATCATGCTATCCAAGAACCACTGGGCAATTCTACAATGCCTCCCAAAGG CCCACCAGGAAGGTTATCTTGAGCACTTTTCAAAGCCCCCCCGCCCGCAGTGCCCCCATC TTTCACACAACAACCTTCGATGGCTTTTGCTCAGCTCCGCCTACAGCTTACTTCCTGCCC TTGGCCACCCACCGTTACCCCCACTATTCCTATACCCCTTTTTGAGCCCCAACGTCTCCA CCCTGCTCCATCCT >OriGene 3' read for NM_005375 unedited
CGGCACGCAATCTAGAATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTAAAATAAGGGCAC ATCTTTATTTTGCTACAAGGCAGTAAGTACACCGTCATATCTCAAAAGTTCAGTGCTGGC CATCTTGCATCAAATGTTCTTAAGGCAGTGACTGGCTATCAACCACAGTTTCTGTCTCCC CAGTTGCAAACACAGGATCCATGCAACAGTTCTGAGACCATACACTTAGAAACCACAGGG GATGCGGATCAAATGCAGAACTCCCAAATTATAAAACAGTCAGGCTACACTCAAAACAAA ACATAGAACATCAACAACACACATCTCCCAAAAAAGAAGTGCAACGCATGCTTGTATAAA CCAACAATAACAAAAAAACCACAATAAAAAATGCAGAGTCTCCCAAACAAGTTTTCAAAT GTATTGCAGAAGGAAAAAAAATGTATATATATATAAAATTAAAAAGTCTGAAATACTAGT GCATAGTCAATTACCTAACACCAAGTTTCTTTTCTTTCTGTCCAAGCTCTACTGCCCCTC TGATACTAGCAGCATGTCTACAGGCTAAGACCATAGCAGCAAAAAACGTTTTTCATTTGG CATTTACAAAATTAAATTACTGAATAAAAATATAATTTTTTATAAAACTATTTCTTACAG TAATAATTTTTAAAGCAAGCTAACAGAAAACTCATAAAATGGTTTGGTACAATAAATGTA CCTTCAATGTCATTAACCATAAATGAGCATTTACCATCTGGATTAAATGTCACATGGTAT TAAGTCTACACTTANAGTAATGCTCTTACTGATTTCTAAAATATATGCATATGCCTAGTG ATCGAGAAAGTGAAATACTGGAGTACCCTTTAATGTGTCAAATTTCAAAAAACCATCACA GGAAAAATACTGTCTGTTGGACCCTTAAATACAGATAATCACTTTAGTTTTTTTTAAAAA ACTGCCTAAGAATTACACTGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005375 |
| Insert Size | 1923 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005375.2, NP_005366.2 |
| RefSeq Size | 3342 bp |
| RefSeq ORF | 1923 bp |
| Locus ID | 4602 |
| UniProt ID | P10242 |
| Domains | myb_DNA-binding |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transcription Factors |
| Gene Summary | This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Transcript Variant: This variant (2, also known as M15024) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) is shorter than isoform 1. |
Citations (6)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Regulation of MYB mediated cisplatin resistance of ovarian cancer cells involves miR-21-wnt signaling axis
,Zhang, XY;Li, YF;Ma, H;Gao, YH;,
Sci Rep
,PubMed ID 32327705
[MYB]
|
|
MicroRNA-150-5p promotes cell motility by inhibiting c-Myb-mediated Slug suppression and is a prognostic biomarker for recurrent ovarian cancer
,Tung, CH;Kuo, LW;Huang, MF;Wu, YY;Tsai, YT;Wu, JE;Hsu, KF;Chen, YL;Hong, TM;,
Oncogene
,PubMed ID 31570789
[MYB]
|
|
Modulation of Myb-induced NF-kB -STAT3 signaling and resulting cisplatin resistance in ovarian cancer by dietary factors
,Tian, M;Tian, D;Qiao, X;Li, J;Zhang, L;,
J. Cell. Physiol.
,PubMed ID 31037726
[MYB]
|
|
p53 gain‐of‐function mutations increase Cdc7‐dependent replication initiation
,null,
EMBO Reports
,PubMed ID 28887320
[MYB]
|
|
Myb overexpression overrides androgen depletion–induced cell cycle arrest and apoptosis in prostate cancer cells, and confers aggressive malignant traits: potential role in castration resistance
,Sanjeev K. Srivastava, Arun Bhardwaj, Seema Singh, Sumit Arora, Steven McClellan, William E. Grizzle, Eddie Reed, and Ajay P. Singh,
Carcinogenesis, Apr 2012; 10.1093/carcin/bgs134.
[MYB]
|
|
c-myb activates CXCL12 transcription in T47D and MCF7 breast cancer cells
,Li Chen, Siguang Xu, Xiaohua Zeng, Junjie Li, Wenjin Yin, Ying Chen, Zhimin Shao, and Wei Jin,
Acta Biochim Biophys Sin, Jan 2010; 42: 1 - 7
[MYB]
|
Documents
| Product Manuals |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209061 | MYB (Myc-DDK-tagged)-Human v-myb myeloblastosis viral oncogene homolog (avian) (MYB), transcript variant 2 |
CNY 7,144.00 |
|
| RC209061L1 | Lenti ORF clone of Human v-myb myeloblastosis viral oncogene homolog (avian) (MYB), transcript variant 2, Myc-DDK-tagged |
CNY 9,544.00 |
|
| RC209061L2 | Lenti ORF clone of Human v-myb myeloblastosis viral oncogene homolog (avian) (MYB), transcript variant 2, mGFP tagged |
CNY 9,544.00 |
|
| RC209061L3 | Lenti ORF clone of Human v-myb myeloblastosis viral oncogene homolog (avian) (MYB), transcript variant 2, Myc-DDK-tagged |
CNY 9,544.00 |
|
| RC209061L4 | Lenti ORF clone of Human v-myb myeloblastosis viral oncogene homolog (avian) (MYB), transcript variant 2, mGFP tagged |
CNY 9,544.00 |
|
| RG209061 | MYB (tGFP-tagged) - Human v-myb myeloblastosis viral oncogene homolog (avian) (MYB), transcript variant 2 |
CNY 8,744.00 |
