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MRE11 (NM_005591) Human Untagged Clone
CAT＃: SC116673
MRE11A (untagged)-Human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1
CNY 5,192.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ATLD; HNGS1; MRE11A; MRE11B |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC116673 sequence for NM_005591 edited (data generated by NextGen Sequencing)
ATGAGTACTGCAGATGCACTTGATGATGAAAACACATTTAAAATATTAGTTGCAACAGAT ATTCATCTTGGATTTATGGAGAAAGATGCAGTCAGAGGAAATGATACGTTTGTAACACTC GATGAAATTTTAAGACTTGCCCAGGAAAATGAAGTGGATTTTATTTTGTTAGGTGGTGAT CTTTTTCATGAAAATAAGCCCTCAAGGAAAACATTACATACCTGCCTCGAGTTATTAAGA AAATATTGTATGGGTGATCGGCCTGTCCAGTTTGAAATTCTCAGTGATCAGTCAGTCAAC TTTGGTTTTAGTAAGTTTCCATGGGTGAACTATCAAGATGGCAACCTCAACATTTCAATT CCAGTGTTTAGTATTCATGGCAATCATGACGATCCCACAGGGGCAGATGCACTTTGTGCC TTGGACATTTTAAGTTGTGCTGGATTTGTAAATCACTTTGGACGTTCAATGTCTGTGGAG AAGATAGACATTAGTCCGGTTTTGCTTCAAAAAGGAAGCACAAAGATTGCGCTATATGGT TTAGGATCCATTCCAGATGAAAGGCTCTATCGAATGTTTGTCAATAAAAAAGTAACAATG TTGAGACCAAAGGAAGATGAGAACTCTTGGTTTAACTTATTTGTGATTCATCAGAACAGG AGTAAACATGGAAGTACTAACTTCATTCCAGAACAATTTTTGGATGACTTCATTGATCTT GTTATCTGGGGCCATGAACATGAGTGTAAAATAGCTCCAACCAAAAATGAACAACAGCTG TTTTATATCTCACAACCTGGAAGCTCAGTGGTTACTTCTCTTTCCCCAGGAGAAGCTGTA AAGAAACATGTTGGTTTGCTGCGTATTAAAGGGAGGAAGATGAATATGCATAAAATTCCT CTTCACACAGTGCGGCAGTTTTTCATGGAGGATATTGTTCTAGCTAATCATCCAGACATT TTTAACCCAGATAATCCTAAAGTAACCCAAGCCATACAAAGCTTCTGTTTGGAGAAGATT GAAGAAATGCTTGAAAATGCTGAACGGGAACGTCTGGGTAATTCTCACCAGCCAGAGAAG CCTCTTGTACGACTGCGAGTGGACTATAGTGGAGGTTTTGAACCTTTCAGTGTTCTTCGC TTTAGCCAGAAATTTGTGGATCGGGTAGCTAATCCAAAAGACATTATCCATTTTTTCAGG CATAGAGAACAAAAGGAAAAAACAGGAGAAGAGATCAACTTTGGGAAACTTATCACAAAG CCTTCAGAAGGAACAACTTTAAGGGTAGAAGATCTTGTAAAACAGTACTTTCAAACCGCA GAGAAGAATGTGCAGCTCTCACTGCTAACAGAAAGAGGGATGGGTGAAGCAGTACAAGAA TTTGTGGACAAGGAGGAGAAAGATGCCATTGAGGAATTAGTGAAATACCAGTTGGAAAAA ACACAGCGATTTCTTAAAGAACGTCATATTGATGCCCTCGAAGACAAAATCGATGAGGAG GTACGTCGTTTCAGAGAAACCAGACAAAAAAATACTAATGAAGAAGATGATGAAGTCCGT GAGGCTATGACCAGGGCCAGAGCACTCAGATCTCAGTCAGAGGAGTCTGCTTCTGCCTTT AGTGCTGATGACCTTATGAGTATAGATTTAGCAGAACAGATGGCTAATGACTCTGATGAT AGCATCTCAGCAGCAACCAACAAAGGAAGAGGCCGAGGAAGAGGTCGAAGAGGTGGAAGA GGGCAGAATTCAGCATCGAGAGGAGGGTCTCAAAGAGGAAGAGCAGACACTGGTCTGGAG ACTTCTACCCGTAGCAGGAACTCAAAGACTGCTGTGTCAGCATCTAGAAATATGTCTATT ATAGATGCCTTTAAATCTACAAGACAGCAGCCTTCCCGAAATGTCACTACTAAGAATTAT TCAGAGGTGATTGAGGTAGATGAATCAGATGTGGAAGAAGACATTTTTCCTACCACTTCA AAGACAGATCAAAGGTGGTCCAGCACATCACCCAGCAAAATCATGTCCCAGAGTCAAGTA TCGAAAGGGGTTGATTTTGAATCAAGTGAGGATGATGATGATGATCCTTTTATGAACACT AGTTCTTTAAGAAGAAATAGAAGATAA Clone variation with respect to NM_005591.3 2011 t=>c >OriGene 5' read for NM_005591 unedited
GCACGAGGGCGGGTTCTCAGAGGCAAGTTCAGACCGTGTTGTTTTCTTTTCACGGATCCT GCCCTTTCTTCCCGAAAAGAAGACAGCCTTGGGTCGCGATTGTGGGGCTTCGAAGAGTCC AGCAGTGGGAATTTCTAGAATTTGGAATCGAGTGCATTTTCTGACATTTGAGTACAGTAC CCAGGGGTTCTTGGAGAAGAACCTGGTCCCAGAGGAGCTTGACTGACCATAAAAATGAGT ACTGCAGATGCACTTGATGATGAAAACACATTTAAAATATTAGTTGCAACAGATATTCAT CTTGGATTTATGGAGAAAGATGCAGTCAGAGGAAATGATACGTTTGTAACACTCGATGAA ATTTTAAGACTTGCCCAGGAAAATGAAGTGGATTTTATTTTGTTAGGTGGTGATCTTTTT CATGAAAATAAGCCCTCAGGAAAACATTACATACCTGCCTCGAGTTATTAAGAAAATATT GTATGGGTGATCGGCCTGTCCAGTTTGAAATTCTCAGTGATCAGTCAGTCAACTTTGGTT TTAGTAAGTTTCCATGGGTGAACTATCAAGATGGCAACCTCAACA >OriGene 3' read for NM_005591 unedited
GAACGCGGCACGCAATCTATAATCGAGTTTTTTTTTTTTTTTTTTCTTATGAAAAGAAAG TAAAAGGTAGCTTTATTTTAATCTTTACTCAAGAGTGATATTGAAACAAAGCTCTTACTA CAACAACCAGGTTAAAAAAACAAGGTGAATCAATGCTATTGTATGTCTGTGAACTAAAAA TTTCTTACTTATGGAGTTATGCTCAGGAAACAATACTTAAAATCTTAAACTGTAAACTCT TAGCTTGTAACATTTTCATTTTTCCTGTATCTTGCATGTTTCTCAGTGCCATTAAATATA TTATCTTCTATTTCTTCTTAAAGAACTAGTGTTCATAAAAGGATCATCATCATCATCCTC ACTTGATTCAAAATCAACCCCTTTCGATACTTGACTCTGGGACATGATTTTGCTGGGTGA TGTGCTGGACCACCTTTGATCTGTCTTTGAAGTGGTAGGAAAAATGTCTTCTTCCACATC TGATTCATCTACCTCAATCACCTCTGAATAATTCTTAGTAGTGACATTTCGGGAAGGCTG CTGTCTTGTAGATTTAAAGGCATCTATAATAGACATATTTCTAGATGCTGACACAGCAGT CTTTGAGTTCCTGCTACGGGTAGAAGTCTCCAGACCAGTGTCTGCTCTTCCTCTTTGAGA CCCTCCTCTCGATGCTGAATTCTGCCCTCTTCCACCTCTTCGACCTCTTCCTCGGCCTCT TCCTTTGTTGGTTGCTGCTGAGATGCTATCATCAGAGTCATTAGCCATCTGTTCTGCTAA ATCTATACTCATAAGGTCATCAGCACTTAAAGCAGAAACAGACTTCTCTGACTGAGATCT GAGTGCTCTGGCCCTGGTCATAGCCTCACAGACTCATCATCTCTTCATTAAAATTTTTTG CCTGGTTCTCTGAACAAGTACCTCTCATG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005591 |
| Insert Size | 3040 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005591.3, NP_005582.1 |
| RefSeq Size | 5141 bp |
| RefSeq ORF | 2127 bp |
| Locus ID | 4361 |
| UniProt ID | P49959 |
| Domains | Metallophos, Mre11_DNA_bind |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Homologous recombination, Non-homologous end-joining |
| Gene Summary | This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the longer isoform of this protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209414 | MRE11A (Myc-DDK-tagged)-Human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1 |
CNY 5,184.00 |
|
| RC209414L1 | Lenti ORF clone of Human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1, Myc-DDK-tagged |
CNY 7,584.00 |
|
| RC209414L2 | Lenti ORF clone of Human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1, mGFP tagged |
CNY 7,700.00 |
|
| RC209414L3 | Lenti ORF clone of Human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1, Myc-DDK-tagged |
CNY 7,584.00 |
|
| RC209414L4 | Lenti ORF clone of Human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1, mGFP tagged |
CNY 7,584.00 |
|
| RG209414 | MRE11A (tGFP-tagged) - Human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1 |
CNY 6,784.00 |
|
| SC322679 | MRE11A (untagged)-Human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1 |
CNY 5,192.00 |
