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Legumain (LGMN) (NM_005606) Human Untagged Clone
CAT＃: SC116627
LGMN (untagged)-Human legumain (LGMN), transcript variant 1
CNY 3,656.00
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AEP; LGMN1; PRSC1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC116627 sequence for NM_005606 edited (data generated by NextGen Sequencing)
ATGGTTTGGAAAGTAGCTGTATTCCTCAGTGTGGCCCTGGGCATTGGTGCCATTCCTATA GATGATCCTGAAGATGGAGGCAAGCACTGGGTGGTGATCGTGGCAGGTTCAAATGGCTGG TATAATTATAGGCACCAGGCAGACGCGTGCCATGCCTACCAGATCATTCACCGCAATGGG ATTCCTGACGAACAGATCGTTGTGATGATGTACGATGACATTGCTTACTCTGAAGACAAT CCCACTCCAGGAATTGTGATCAACAGGCCCAATGGCACAGATGTCTATCAGGGAGTCCCG AAGGACTACACTGGAGAGGATGTTACCCCACAAAATTTCCTTGCTGTGTTGAGAGGCGAT GCAGAAGCAGTGAAGGGCATAGGATCCGGCAAAGTCCTGAAGAGTGGCCCCCAGGATCAC GTGTTCATTTACTTCACTGACCATGGATCTACTGGAATACTGGTTTTTCCCAATGAAGAT CTTCATGTAAAGGACCTGAATGAGACCATCCATTACATGTACAAACACAAAATGTACCGA AAGATGGTGTTCTACATTGAAGCCTGTGAGTCTGGGTCCATGATGAACCACCTGCCGGAT AACATCAATGTTTATGCAACTACTGCTGCCAACCCCAGAGAGTCGTCCTACGCCTGTTAC TATGATGAGAAGAGGTCCACGTACCTGGGGGACTGGTACAGCGTCAACTGGATGGAAGAC TCGGACGTGGAAGATCTGACTAAAGAGACCCTGCACAAGCAGTACCACCTGGTAAAATCG CACACCAACACCAGCCACGTCATGCAGTATGGAAACAAAACAATCTCCACCATGAAAGTG ATGCAGTTTCAGGGTATGAAACGCAAAGCCAGTTCTCCCGTCCCCCTACCTCCAGTCACA CACCTTGACCTCACCCCCAGCCCTGATGTGCCTCTCACCATCATGAAAAGGAAACTGATG AACACCAATGATCTGGAGGAGTCCAGGCAGCTCACGGAGGAGATCCAGCGGCATCTGGAT GCCAGGCACCTCATTGAGAAGTCAGTGCGTAAGATCGTCTCCTTGCTGGCAGCGTCCGAG GCTGAGGTGGAGCAGCTCCTGTCCGAGAGAGCCCCGCTCACGGGGCACAGCTGCTACCCA GAGGCCCTGCTGCACTTCCGGACCCACTGCTTCAACTGGCACTCCCCCACGTACGAGTAT GCGTTGAGACATTTGTACGTGCTGGTCAACCTTTGTGAGAAGCCGTATCCACTTCACAGG ATAAAATTGTCCATGGACCACGTGTGCCTTGGTCACTACTGA Clone variation with respect to NM_005606.6 52 g=>a;720 t=>c;1251 g=>a >OriGene 5' read for NM_005606 unedited
ATTTGTATACGACTACTATAGGGCGGCCGCGAATTCGCACGAGGGCCCGCAGCAATCACA GCAGTGCCGACGTCGTGGGTGTTTGGTGTGAGGCTGCGAGCCGCCGCGAGTTCTCACGGT CCCGCCGGCGCCACCACCGCGGTCACTCACCGCCGCCGCCGCCACCACTGCCACCACGGT CGCCTGCCACAGGTGTCTGCAATTGAACTCCAAGGTGCAGAATGGTTTGGAAAGTAGCTG TATTCCTCAGTGTGGCCCTGGGCATTGGTGCCATTCCTATAGATGATCCTGAAGATGGAG GCAAGCACTGGGTGGTGATCGTGGCAGGTTCAAATGGCTGGTATAATTATAGGCACCAGG CAGACGCGTGCCATGCCTACCAGATCATTCACCGCAATGGGATTCCTGACGAACAGATCG TTGTGATGATGTACGATGACATTGCTTACTCTGAAGACAATCCCACTCCAGGAATTGTGA TCAACAGGCCCAATGGCACAGATGTCTATCAGGGAGTCCCGAAGGACTACACTGGAGAGG ATGTTACCCCACAAAATTTCCTTGCTGTGTTGAGAGGCGATGCANAAGCAGTGAAGGGCA TAGGATCCGGCAAAGTCCTGAAGAGTGGCCCCCAGGATCACGTGTTCATTTACTTCACTG ACCATGGATCTACTGGAATACTGGTTTTTCCCAATGAAGATCTTCATGTAAAGGACCTGA ATGAGACCATNCATTACATGTACAAACACANAATGTACCGAAGGATGGTGTTCACATTGA AGCCTGTGAAGTCTGGGTCATGATGAACCACCTGCNCGATACATCATGGTTATGCACTAC TGCTGCCACCCAGAGAGTCGTCTACGCTGTACATGATNANAAAAAGTCCACTCCTGNGGG ACTGGTACGCGTCATGGATGGAAAACTCGACCGGGAGATTGCTAAGAGACCTGNCAGCAG TCCACTGTTAATCT >OriGene 3' read for NM_005606 unedited
AGCTATGGACCGCGCGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGGTTCTG TTATAAATCTTTATTTTTTAAGACTTGAACACCTGCAGAATTAAATACAAAAGCAATCAA AAATCATCATATTTTCTAAAAACAGTTTTCCATTTGGGGCTTGCGGCCCTCTTCAATAAA ATCATTCTGAAGATTTAAAGAGGTTTCAGCTTCAAATTCTCAGAATAAAGACTCCTTTTG AGAGGGGCTACAGAAGCCCCCATGAGCTTCCTGCTCCTCAAAACTAACAGGCAAAACAAC AAACCTCCTAGAAAGCAAATATGACCCTTCTCAATACAGAGCTTTTCCCACCCTAATTTG TAGTTTTTCAGAAAAGACTGGGGAAGCAGGTAACAGCGAGCAAGTCATCTTGTGAAGAAG GTCCTGGAGCGAGCCCTGGAGCGGGGGCTCCCCAGGAGGGCCCGAGCAGCGGAGACTTCT CACTCCACCTCTCCAGTCTCTGATCAGCACACAGTCGGTGGGGCGCTCACACTTGGAAAA GCTTCCAGGAGGCAGCTCTTCAGTAGTGACCAAGGCACACGTGGTCCATGGACAATTTTA TCCTGTGAAGTGGATACGGCTTCTCACAAAGGTTGACCAGCACGTACAAATGTCTCAACG CATACTCGTACGTGGGGGAGTGCCAGTTGAAGCAGTGGGTCCCGAAGTGCAGCAGGGCCT CTGGGTAGCAGCTGTGCCCCGTGNAGCGNGCTCTCTTCGACAGGAGCTGNTCCCCTNAGC CTCGNACGCTGCCACCAAGAGACGATCTTACGCACTGACTTTCTCATGAGTGCCTGCCAT CCAGATGCCGCTGGATCTCTCCCGGAGCTGCCTGGACTCCCCAGATCATTGNNGTCATCA GTTCCCTTTCATGATAGGGAGAGCACATCAAGCCTGGGGTGAGGCCCAGTGTGTGACTGG AG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005606 |
| Insert Size | 2140 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005606.5, NP_005597.3 |
| RefSeq Size | 2048 bp |
| RefSeq ORF | 1302 bp |
| Locus ID | 5641 |
| UniProt ID | Q99538 |
| Domains | Peptidase_C13 |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Antigen processing and presentation, Lysosome |
| Gene Summary | This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the predominant transcript. Variants 1 and 2 encode the same isoform. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224975 | LGMN (Myc-DDK-tagged)-Human legumain (LGMN), transcript variant 1 |
CNY 3,656.00 |
|
| RC224975L1 | Lenti ORF clone of Human legumain (LGMN), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC224975L2 | Lenti ORF clone of Human legumain (LGMN), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC224975L3 | Lenti ORF clone of Human legumain (LGMN), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC224975L4 | Lenti ORF clone of Human legumain (LGMN), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG224975 | LGMN (tGFP-tagged) - Human legumain (LGMN), transcript variant 1 |
CNY 5,256.00 |
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