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Plzf (ZBTB16) (NM_006006) Human Untagged Clone
CAT＃: SC116350
ZBTB16 (untagged)-Human zinc finger and BTB domain containing 16 (ZBTB16), transcript variant 1
CNY 7,408.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PLZF; ZNF145 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC116350 sequence for NM_006006 edited (data generated by NextGen Sequencing)
ATGGATCTGACAAAAATGGGCATGATCCAGCTGCAGAACCCTAGCCACCCCACGGGGCTA CTGTGCAAGGCCAACCAGATGCGGCTGGCCGGGACTTTGTGCGATGTGGTCATCATGGTG GACAGCCAGGAGTTCCACGCCCACCGGACGGTGCTGGCCTGCACCAGCAAGATGTTTGAG ATCCTCTTCCACCGCAATAGTCAACACTATACTTTGGACTTCCTCTCGCCAAAGACCTTC CAGCAGATTCTGGAGTATGCATATACAGCCACGCTGCAAGCCAAGGCGGAGGACCTGGAT GACCTGCTGTATGCGGCCGAGATCCTGGAGATCGAGTACCTGGAGGAACAGTGCCTGAAG ATGCTGGAGACCATCCAGGCCTCAGACGACAATGACACGGAGGCCACCATGGCCGATGGC GGGGCCGAGGAAGAAGAGGACCGCAAGGCTCGGTACCTCAAGAACATCTTCATCTCGAAG CATTCCAGCGAGGAGAGTGGGTATGCCAGTGTGGCTGGACAGAGCCTCCCTGGGCCCATG GTGGACCAGAGCCCTTCAGTCTCCACTTCATTTGGTCTTTCAGCCATGAGTCCCACCAAG GCTGCAGTGGACAGTTTGATGACCATAGGACAGTCTCTCCTGCAGGGAACTCTTCAGCCA CCTGCAGGGCCCGAGGAGCCAACTCTGGCTGGGGGTGGGCGGCACCCTGGGGTGGCTGAG GTGAAGACGGAGATGATGCAGGTGGATGAGGTGCCCAGCCAGGACAGCCCTGGGGCAGCC GAGTCCAGCATCTCAGGAGGGATGGGGGACAAGGTTGAGGAAAGAGGCAAAGAGGGGCCT GGGACCCCGACTCGAAGCAGCGTCATCACCAGTGCTAGGGAGCTACACTATGGGCGAGAG GAGAGTGCCGAGCAGGTGCCACCCCCAGCTGAGGCTGGCCAGGCCCCCACTGGCCGACCT GAGCACCCAGCACCCCCGCCTGAGAAGCATCTGGGCATCTACTCCGTGTTGCCCAACCAC AAGGCTGACGCTGTATTGAGCATGCCGTCTTCCGTGACCTCTGGCCTCCACGTGCAGCCT GCCCTGGCTGTCTCCATGGACTTCAGCACCTATGGGGGGCTGCTGCCCCAGGGCTTCATC CAGAGGGAGCTGTTCAGCAAGCTGGGGGAGCTGGCTGTGGGCATGAAGTCAGAGAGCCGG ACCATCGGAGAGCAGTGCAGCGTGTGTGGGGTCGAGCTTCCTGATAACGAGGCTGTGGAG CAGCACAGGAAGCTGCACAGTGGGATGAAGACGTACGGGTGCGAGCTCTGCGGGAAGCGG TTCCTGGATAGTTTGCGGCTGAGAATGCACTTACTGGCTCATTCAGCGGGTGCCAAAGCC TTTGTCTGTGATCAGTGCGGTGCACAGTTTTCGAAGGAGGATGCCCTGGAGACACACAGG CAGACCCATACTGGCACTGACATGGCCGTCTTCTGTCTGCTGTGTGGGAAGCGCTTCCAG GCGCAGAGCGCACTGCAGCAGCACATGGAGGTCCACGCGGGCGTGCGCAGCTACATCTGC AGTGAGTGCAACCGCACCTTCCCCAGCCACACGGCTCTCAAACGCCACCTGCGCTCACAT ACAGGCGACCACCCCTACGAGTGTGAGTTCTGTGGCAGCTGCTTCCGGGATGAGAGCACA CTCAAGAGCCACAAACGCATCCACACGGGTGAGAAACCCTACGAGTGCAATGGCTGTGGC AAGAAGTTCAGCCTCAAGCATCAGCTGGAGACGCACTATAGGGTGCACACAGGTGAGAAG CCCTTTGAGTGTAAGCTCTGCCACCAGCGCTCCCGGGACTACTCGGCCATGATCAAGCAC CTGAGAACGCACAACGGCGCCTCGCCCTACCAGTGCACCATCTGCACAGAGTACTGCCCC AGCCTCTCCTCCATGCAGAAGCACATGAAGGGCCACAAGCCCGAGGAGATCCCGCCCGAC TGGAGGATAGAGAAGACGTACCTCTACCTGTGCTATGTGTGA Clone variation with respect to NM_006006.4 >OriGene 5' read for NM_006006 unedited
TTCCCCGCCCGTTGGCGCAAAGGGCGGTAGGCGTGTACGGTGGNGAGTCTATATAAGCAG AGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAAT TCGGCACGAGGGGCGATGAGAGCGGGTACTGCGAACTGCCGGGCGATGCTGTCGCTGCCG CCGTGATACGGAGAGCAACAGTTCCCCAGCAACACCCCTCCCCGACACAGGCACACACCC CCCGACAGGCACGCACACCCACCCCACAGTGCCCGGCTCGGCTGCGCCTCCTCTATTGGC CCAGGAAGCCCACCCAGCCCCGCCACGCAGAGCCCAGAAGGAAAGAAAGCCTCATGCCTG AGCCGAGGGGAGCACCATGGATCTGACAAAAATGGGCATGATCCAGCTGCAGAACCCTAG CCACCCCACGGGGCTACTGTGCAAGGCCAACCAGATGCGGCTGGCCGGGACTTTGTGCGA TGTGGTCATCATGGTGGACAGCCAGGAGTTCCACGCCCACCGGACGGTGCTGGCCTGCAC CAGCAAGATGTTTGAGATCCTCTTCCACCGCAATAGTCAACACTATACTTTGGACTTCCT CTCGCCAAAGACCTTCCAGCAGATTCTGGAGTATGCATATACAGCCACGCTGCAAGCCAA GGCGGAGGACCTGGATGACCTGCTGTATGCGGCCGAGATCCTGGAGATCGAGTACCTGGN AGAACAGTGCCTGAAGATGCTGGAGACCATNNCAGCCTCAGACGATCATGACACGGGAGC CACCATGGCCGATGGCGGNGCCGAGAATGATAAGACCCGCAGGGCTCGTACCTCAGAAAC ATCTCATCTCGAACCATTCANCGAGGANAGTGGGTATGCCAGTGTGGCTGGACAGGAGCC TCCTGGGCCAATGGTAGGACCAGAGCCCTTAGTCTCCA >OriGene 3' read for NM_006006 unedited
ATTTACTAGTCCTTCCTCTCTCACTCCACTCTTCTTTCCTGGCTCCCCGCTCGGCTCCAC CGCCGCGGGCGCTCCCTTCACACATAGCACAGGTAGAGGTACGTCTTCTCTATCCTCCAG TCGGGCGGGATCTCCTCGGGCTTGTGGCCCTTCATGTGCTTCTGCATGGAGGAGAGGCTG GGGCAGTACTCTGTGCAGATGGTGCACTGGTAGGGCGAGGCGCCGTTGTGCGTTCTCAGG TGCGGGAGCATGGCCGAGTAGTCCCGGGAGCGCTGGTGGCAGAGCTTACACTCAAAGGGC TTCTCACCTGTGTGCACCCTATAGTGCGTCTCCAGCTGATGCTTGAGGCTGAACTTCTTG CCACAGCCATTGCACTCGTAGGGTTTCTCACCCGTGTGGATGCGTTTGTGGCTCTTGAGT GTGCTCTCATCCCGGAAGCAGCTGCCACACAACTCACACTTCTAGGGGTGGTCGCCTGTA TGTGAGCGCACCTGGCGCCTGAGAGCCTTGCTGCTTGTGAACGGGCAGTTTCCCTCACAC CAAATGTTCCTCCCCACCACCCCCTGCGCTTCCTTCTCCCCCCCCCAACGCCCCCCGCCC CCCCGGCCTCTTTGTCTTCGTTCTCACCTCACACCCTCCCGCCCCTCTTACATATCCTCT CCTCTACTCCCCCCCCCACCCTCCCCCTCCACCAACCCGTATTCTCCACAATCTTTACCC ACATCCCCGACCGCCAAACTATACACTTAATGCCCCATCTTCACGCCCCCATCCCCTCCA CCCCCCCCCCCCCCCCCACTCCTCGTTCGCACGACTTAGCCTTTCTGTTTGTACCTATCA TACACTCCCCACCCTCCCTCCATACCCCCCCCCTTCCCTCCCCCCCCCAATCCCTCTCCC GACTGTAATTTGTCATCCTCTACTGGTGCCGC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006006 |
| Insert Size | 2550 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006006.4, NP_005997.2 |
| RefSeq Size | 2417 bp |
| RefSeq ORF | 2022 bp |
| Locus ID | 7704 |
| UniProt ID | Q05516 |
| Domains | BTB, zf-C2H2 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Acute myeloid leukemia, Pathways in cancer |
| Gene Summary | This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 encode the same protein. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The promyelocytic leukemia zinc finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival
,null,
Oncogene
,PubMed ID 20010871
[ZBTB16]
|
|
The promyelocytic leukemia zinc-finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival
,M Cheung, J Pei, Y Pei, S C Jhanwar, H I Pass, J R Testa,
Oncogene (14 December 2009) doi:10.1038/onc.2009.455 Original Article
[ZBTB16]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206745 | ZBTB16 (Myc-DDK-tagged)-Human zinc finger and BTB domain containing 16 (ZBTB16), transcript variant 1 |
CNY 7,392.00 |
|
| RC206745L1 | Lenti ORF clone of Human zinc finger and BTB domain containing 16 (ZBTB16), transcript variant 1, Myc-DDK-tagged |
CNY 9,792.00 |
|
| RC206745L2 | Lenti ORF clone of Human zinc finger and BTB domain containing 16 (ZBTB16), transcript variant 1, mGFP tagged |
CNY 9,792.00 |
|
| RC206745L3 | Lenti ORF clone of Human zinc finger and BTB domain containing 16 (ZBTB16), transcript variant 1, Myc-DDK-tagged |
CNY 9,792.00 |
|
| RC206745L4 | Lenti ORF clone of Human zinc finger and BTB domain containing 16 (ZBTB16), transcript variant 1, mGFP tagged |
CNY 9,792.00 |
|
| RG206745 | ZBTB16 (tGFP-tagged) - Human zinc finger and BTB domain containing 16 (ZBTB16), transcript variant 1 |
CNY 8,992.00 |
