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FRS2 (NM_006654) Human Untagged Clone
CAT＃: SC115938
FRS2 (untagged)-Human fibroblast growth factor receptor substrate 2 (FRS2), transcript variant 1
CNY 3,824.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FRS1A; FRS2A; FRS2alpha; SNT; SNT-1; SNT1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115938 sequence for NM_006654 edited (data generated by NextGen Sequencing)
ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAG TTTAAGGTCATTAATGTGGATGATGATGGGAATGAGTTAGGTTCTGGCATAATGGAACTT ACAGACACAGAACTGATTTTATACACCCGCAAACGTGACTCAGTAAAATGGCACTACCTC TGCCTGCGACGCTATGGCTATGACTCGAATCTCTTTTCTTTTGAAAGTGGTCGAAGGTGT CAAACTGGACAAGGAATCTTTGCCTTTAAGTGTGCCCGTGCAGAAGAATTATTTAACATG TTGCAAGAGATTATGCAAAATAATAGTATAAATGTGGTGGAAGAGCCAGTTGTAGAAAGA AATAATCATCAGACAGAATTGGAAGTCCCTAGAACACCTCGAACACCTACAACTCCAGGA TTTGCTGCTCAGAACTTACCTAATGGATATCCCCGATATCCCTCATTTGGAGATGCTTCA TCCCATCCGTCAAGCAGACATCCTTCTGTGGGAAGTGCTCGCCTGCCTTCAGTAGGGGAA GAATCTACACATCCTTTGCTTGTGGCTGAGGAACAAGTACATACCTATGTCAACACTACA GGTGTGCAAGAAGAGCGGAAAAACCGCACAAGTGTGCATGTTCCATTGGAGGCGAGGGTT TCTAACGCTGAAAGCAGCACACCAAAAGAAGAACCAAGTAGTATTGAGGACAGGGATCCT CAGATTCTTCTTGAACCTGAAGGAGTCAAATTTGTTTTAGGGCCAACCCCTGTTCAAAAG CAGTTAATGGAAAAAGAGAAACTGGAGCAACTTGGAAGAGATCAAGTTAGTGGAAGTGGA GCAAATAACACAGAATGGGACACTGGCTATGACAGTGATGAACGAAGAGATGCACCCTCT GTTAACAAACTGGTGTATGAAAATATAAATGGGCTATCTATCCCTAGTGCCTCAGGGGTC AGGAGAGGTCGTCTGACATCCACCAGTACCTCAGATACCCAGAATATCAACAACTCAGCT CAGAGAAGAACTGCATTATTAAACTATGAAAATCTACCATCTTTGCCTCCTGTTTGGGAA GCCCGCAAGCTAAGTAGGGATGAAGATGACAATTTAGGACCAAAGACCCCATCTCTAAAT GGCTACCATAATAATCTAGATCCAATGCATAACTATGTAAATACAGAGAATGTAACAGTG CCAGCAAGTGCTCACAAAATAGAATATTCAAGGCGTCGGGACTGTACACCAACAGTCTTT AACTTTGATATCAGACGCCCAAGTTTAGAACACAGGCAGCTTAATTACATACAGGTTGAC TTGGAAGGTGGCAGTGACTCTGACAACCCTCAGACTCCAAAAACGCCTACAACTCCCCTT CCACAAACCCCTACCAGGCGCACAGAGCTGTATGCCGTGATAGACATCGAGAGAACTGCT GCTATGTCAAATTTGCAGAAAGCACTGCCACGAGATGATGGTACATCTAGGAAAACTAGA CACAATAGTACTGATCTGCCCATGTGA Clone variation with respect to NM_006654.3 >OriGene 5' read for NM_006654 unedited
TTCGGCACGAGGGCTGCCAGAAAGCTCATAAGGAATATTATTCTTTAGAAATGAGAAATT CTCAATGTTTTTCTTCTGTTTTTAGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTG AAATATGATTAAACTCCTGATGCTGCAGCAGAGGCTAAGAATATTAATGGCCAGATCTAG TGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACA CTGTCCCAGATAACCATCGGAACAAGTTTAAGGTCATTAATGTGGATGATGATGGGAATG AGTTAGGTTCTGGCATAATGGAACTTACAGACACAGAACTGATTTTATACACCCGCAAAC GTGACTCAGTAAAATGGCACTACCTCTGCCTGCGACGCTATGGCTATGACTCGAATCTCT TTTCTTTTGAAAGTGGTCGAAGGTGTCAAACTGGACAAGGAATCTTTGCCTTTAAGTGTG CCCGTGCAGAAGAATTATTTAACATGTTGCAAGAGATTATGCAAAATAATAGTATAAATG TGGTGGAAGAGCCAGTTGTAGAAAGAAATAATCATCAGACAGAATTGGAAGTCCCTAGAA CACCTCGAACACCTACAACTCCAGGATTTGCTGCTCAGAACTTACCTAATGGATATCCCC GATATCCCTCATTTGGAGATGCTTCATCCCATCCGTCAAGCAGACATCCTTCTGTNGGGA AGTGCTCGCCTGCCTTCAGTAGGGGAAGAATCTACACATNCTTTGCTTGTGGCTGAGGAC A >OriGene 3' read for NM_006654 unedited
GGATATTTGGGGTTTTTTTACCCATTTTATGTTTTTATCCACACACACTACACATTGTAC AAAACATTTGGGCCTTGGGGGTTAGGGAAAAACCCGGGGGGAATTGGGAAAACTTTTCTC TGGAAAAACCTTTCCTTGCAGCATAAGATATGGCGGCACATTGTTGGGAAATATGAAAAC TTTAGGCCCCCGCCCCATTTGTAAAAAAACATTTTTGGGGCCCCTTTTTTTTGGCGGGGC CGCGGTTTTGGGGAGGGGGAGGAGATAAACCCTACCTTGACTTGTCCTATTAAAAACCTT GAACCCTGGAGAGAGTCAACATTATTGTCTGTAAAAACAAACTTTGCTCGCCAAATTTTC CTAACTCCCAAATTTGAGGTATTCGGGAAATTCTGGGAAGTGAAAAGCTTTTTGCTGAAT CTTAAAGAGTAAAGTGCATACCTCATCACTCCACAGAAACTTTAAATAAAAGGAAATTTT TGCCAATCTTCCCGGAGGGGGGGAAGGCACCATATTTTCATTTTTAAAAAAAGATGACAC TGGGAAATAAAACACACTAACAAAAACCCTTGTAATACCAATATCGGTTTCCAACCCTAG CATGGGATAGATGCTGATAAGAATTGTCTGGATAAAACAATATCTTTTTGGAGGGAAACT TCACCACGATTAAATTTCCAAACCAGAACGAGGATCACATGGTCAACAAACAAATCTCCT AAAATTTATTCTGCCTCGGAAAACTTAAATTTTTGGCCCACATTTTTGGCTAATAAAAAA AACCTTTTATTTTGAAAAGCCCCCCGGAAGAAGGCCCATCCTTCCGGGGACCAACTTTTG GGCCATTAAAAAAATTTGCAAAGAACCTTTTTTTTTTAAAAACCCCTTTTTTATAAGGAA CCCTTTGGTTTTCTAAAATTTTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006654 |
| Insert Size | 5200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006654.2, NP_006645.2 |
| RefSeq Size | 1840 bp |
| RefSeq ORF | 1539 bp |
| Locus ID | 10818 |
| UniProt ID | Q8WU20 |
| Domains | IRS |
| Protein Families | Druggable Genome |
| Protein Pathways | Neurotrophin signaling pathway |
| Gene Summary | Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) lacks an exon in the 5' UTR, compared to variant 3. All variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205842 | FRS2 (Myc-DDK-tagged)-Human fibroblast growth factor receptor substrate 2 (FRS2), transcript variant 1 |
CNY 3,816.00 |
|
| RC205842L1 | Lenti ORF clone of Human fibroblast growth factor receptor substrate 2 (FRS2), transcript variant 1, Myc-DDK-tagged |
CNY 6,216.00 |
|
| RC205842L2 | Lenti ORF clone of Human fibroblast growth factor receptor substrate 2 (FRS2), transcript variant 1, mGFP tagged |
CNY 6,270.00 |
|
| RC205842L3 | Lenti ORF clone of Human fibroblast growth factor receptor substrate 2 (FRS2), transcript variant 1, Myc-DDK-tagged |
CNY 6,270.00 |
|
| RC205842L4 | Lenti ORF clone of Human fibroblast growth factor receptor substrate 2 (FRS2), transcript variant 1, mGFP tagged |
CNY 6,216.00 |
|
| RG205842 | FRS2 (tGFP-tagged) - Human fibroblast growth factor receptor substrate 2 (FRS2), transcript variant 1 |
CNY 5,416.00 |
