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ADK (NM_006721) Human Untagged Clone
CAT＃: SC115890
ADK (untagged)-Human adenosine kinase (ADK), transcript variant 2
CN¥ 3,656.00
CN¥ 5,800.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AK |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115890 sequence for NM_006721 edited (data generated by NextGen Sequencing)
ATGGCAGCTGCTGAGGAGGAGCCGAAGCCCAAAAAGCTGAAGGTGGAGGCGCCGCAAGCG CTGAGAGAAAATATTCTCTTTGGAATGGGAAATCCTCTGCTTGACATCTCTGCTGTAGTG GACAAAGATTTCCTTGATAAGTATTCTCTGAAACCAAATGACCAAATCTTGGCTGAAGAC AAACACAAGGAACTGTTTGATGAACTTGTGAAAAAATTCAAAGTCGAATATCATGCTGGT GGCTCTACCCAGAATTCAATTAAAGTGGCTCAGTGGATGATTCAACAGCCACACAAAGCA GCAACATTTTTTGGATGCATTGGGATAGATAAATTTGGGGAGATCCTGAAGAGAAAAGCT GCTGAAGCCCATGTGGATGCTCATTACTACGAGCAGAATGAGCAGCCAACAGGAACTTGT GCTGCATGCATCACTGGTGACAACAGGTCCCTCATAGCTAATCTTGCTGCTGCCAATTGT TATAAAAAGGAAAAACATCTTGATCTGGAGAAAAACTGGATGTTGGTAGAAAAAGCAAGA GTTTGTTATATAGCAGGCTTTTTTCTTACAGTTTCCCCAGAGTCAGTATTAAAGGTGGCT CACCATGCTTCTGAAAACAACAGGATTTTCACTTTGAATCTATCTGCACCGTTTATTAGC CAGTTCTACAAGGAATCATTGATGAAAGTTATGCCTTATGTTGATATACTTTTTGGAAAT GAGACAGAAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGACATTAAAGAG ATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACTCAAAGAGGCAGCGAATCGTGATC TTCACCCAAGGGAGAGATGACACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCT GTCTTGGATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGATGCATTTGTT GGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTCTGACTGAATGTATCCGTGCTGGC CACTATGCAGCAAGCATCATAATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGAC TTCCACTGA Clone variation with respect to NM_006721.3 >OriGene 5' read for NM_006721 unedited
NAGCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGT GGGCTGTAGAGCCAAAGTGGGGTGGGAGCGCGAAGATGGCAGCTGCTGAGGAGGAGCCGA AGCCCAAAAAGCTGAAGGTGGAGGCGCCGCAAGCGCTGAGAGAAAATATTCTCTTTGGAA TGGGAAATCCTCTGCTTGACATCTCTGCTGTAGTGGACAAAGATTTCCTTGATAAGTATT CTCTGAAACCAAATGACCAAATCTTGGCTGAAGACAAACACAAGGAACTGTTTGATGAAC TTGTGAAAAAATTCAAAGTCGAATATCATGCTGGTGGCTCTACCCAGAATTCAATTAAAG TGGCTCAGTGGATGATTCAACAGCCACACAAAGCAGCAACATTTTTTGGATGCATTGNGA TAGATAAATTTGGGGAGATCCTGAAGAGAAAGCTGCTGAAGCCCATGTGGATGCTCATTA CTACGAGCAGAATGAGCAGCCAACAGGAACTTGTGCTGCATGCATCACTGGTGAACACAG GTCCCTCATAGCTAATCTTGCTGCTGCCAATTGTTATAAAAAGGAAAAACATCTGATCTG GAGAAAACTGGATGTTGGTAGAAAAGCAAGAGTTTGTATATAGCAGGCTTTTTTCTACAG TTTCCCAGAGTCAGTATTAAAGTGGCTANCATGCTTCTGAAACAACAGGATTTTACTTTG ATCTATCTGCACCGTTATTACCCAGTCTACAGGAATCATTGATGAAGTATGCCTTAGTTT ATATACTTTTTGGAATGAAACAAAACTGCCCTTTTGCTAAAAGCAAGGCTTGANACTAAA ACGTTAAGAGAAGCCAAAAAAACCAACCCTGCGAAAATGACTCGAGAGCCCGAATCT >OriGene 3' read for NM_006721 unedited
ACTTGTACCGCGCCGCATTCTAGATCGAGTTTTTTTCTTTTTTTTTTTTTTTTTTGGCAT CCTTAAAAAATGATTTATTGGTCTCTGATACTAAGTTATTCTTCAGTGTATTATATTGCT GTTCTTCATAATTCCATTAACAAATTGGGTGTCATTTCAGGGCCCAGTATTAAATAATGA TCTTTCTTCCTCAGTTTGCTGTACACAGGGTAAAAGACAGAAAAAAATTCCTATATGACA AGTTTTTGTTTGTATCCAATTACAGAGTTCCATAAGACTATGATTTGAATATTGTGGTAC AACTTAAATTTGGCACATTATTTAATTATCCAAAGTTTATTACATGTTTGAGTGCACATT AAAGAGATTATTTGGCATAATTGACAAGATAAAATTTCTGTACCTTATTTGACTATCAGG TGTATATGTGGTATATTTATGTATGTGTGTGTATAGACACACATATACTCCTAAATTAAA TATATTTGTATAAAAAGCTAAAGATTACTATGTTAAGATTAATTCATTAAAAAATCTATT ATATTAAATTGCATCTGCATTCAAAGCAGAAATGTAAAAAAACAAATCAGTGTACTAAAT ACACACGAATTTACAAAGTAATTGAAAATGAAATAAAAATTTCTATTGAAATGTTATATT CCTTGTTTAAATGGCATTTAAGTGGCACTATCAAACTATGGAAAATAAACATCATTTTTT AGATTGTTGAGATAATAAAGATCTACAAGCCTTACATACCCTTGTACCCTCCTAATTAAA AATCCGCATTTATATTAGTAGGGAAAAATGGCGAAAATTTTCCTCTTTATAATATGGGGA ATCTCAGGAGCCATTAAGGCAATGTCTGCCTTCCGGGGCTTGGGGTTTCAGCCTCTCCAT CAAGGAAAGCCTGGCTTTCAGGAAGGTGGCACCCCTCCCCCCTAATTTGAAGCCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006721 |
| Insert Size | 2100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006721.2, NP_006712.2 |
| RefSeq Size | 2018 bp |
| RefSeq ORF | 1089 bp |
| Locus ID | 132 |
| UniProt ID | P55263 |
| Domains | pfkB |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Purine metabolism |
| Gene Summary | This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] Transcript Variant: This variant (2), alternately referred to as ADK-long, differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) is longer than isoform a. |
Documents
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Resources
Other Versions
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|---|---|---|---|
| RC212888 | ADK (Myc-DDK-tagged)-Human adenosine kinase (ADK), transcript variant 2 |
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| RC212888L3 | Lenti-ORF clone of ADK (Myc-DDK-tagged)-Human adenosine kinase (ADK), transcript variant 2 |
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| RC212888L4 | Lenti-ORF clone of ADK (mGFP-tagged)-Human adenosine kinase (ADK), transcript variant 2 |
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| RG212888 | ADK (tGFP-tagged) - Human adenosine kinase (ADK), transcript variant 2 |
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