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Frizzled 10 (FZD10) (NM_007197) Human Untagged Clone
CAT＃: SC115678
FZD10 (untagged)-Human frizzled family receptor 10 (FZD10)
CNY 6,496.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD350; FZ-10; Fz10; FzE7; hFz10 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_007197 edited
GAATTCGGCACGAGCCAGGCCGGGCGGGCATGGGCGGGGGCCCGAGCAGGGGTGGAGAGC CGGGGCCAGCAGCAGCCCGTGCCCGGGAGCGGCGGCGCTGAGGGGCGCGGAGCTCCCCGC GAGGACACGTCCAACGCCAGCATGCAGCGCCCGGGCCCCCGCCTGTGGCTGGTCCTGCAG GTGATGGGCTCGTGCGCCGCCATCAGCTCCATGGACATGGAGCGCCCGGGCGACGGCAAA TGCCAGCCCATCGAGATCCCGATGTGCAAGGACATCGGCTACAACATGACTCGTATGCCC AACCTGATGGGCCACGAGAACCAGCGCGAGGCAGCCATCCAGTTGCACGAGTTCGCGCCG CTGGTGGAGTACGGCTGCCACGGCCACCTCCGCTTCTTCCTGTGCTCGCTGTACGCGCCG ATGTGCACCGAGCAGGTCTCTACCCCCATCCCCGCCTGCCGGGTCATGTGCGAGCAGGCC CGGCTCAAGTGCTCCCCGATTATGGAGCAGTTCAACTTCAAGTGGCCCGACTCCCTGGAC TGCCGGAAACTCCCCAACAAGAACGACCCCAACTACCTGTGCATGGAGGCGCCCAACAAC GGCTCGGACGAGCCCACCCGGGGCTCGGGCCTGTTCCCGCCGCTGTTCCGGCCGCAGCGG CCCCACAGCGCGCAGGAGCACCCGCTGAAGGACGGGGGCCCCGGGCGCGGCGGCTGCGAC AACCCGGGCAAGTTCCACCACGTGGAGAAGAGCGCGTCGTGCGCGCCGCTCTGCACGCCC GGCGTGGACGTGTACTGGAGCCGCGAGGACAAGCGCTTCGCAGTGGTCTGGCTGGCCATC TGGGCGGTGCTGTGCTTCTTCTCCAGCGCCTTCACCGTGCTCACCTTCCTCATCGACCCG GCCCGCTTCCGCTACCCCGAGCGCCCCATCATCTTCCTCTCCATGTGCTACTGCGTCTAC TCCGTGGGCTACCTCATCCGCCTCTTCGCCGGCGCCGAGAGCATCGCCTGCGACCGGGAC AGCGGCCAGCTCTATGTCATCCAGGAGGGACTGGAGAGCACCGGCTGCACGCTGGTCTTC CTGGTCCTCTACTACTTCGGCATGGCCAGCTCGCTGTGGTGGGTGGTCCTCACGCTCACC TGGTTCCTGGCCGCCGGCAAGAAGTGGGGCCACGAGGCCATCGAAGCCAACAGCAGCTAC TTCCACCTGGCAGCCTGGGCCATCCCGGCGGTGAAGACCATCCTGATCCTGGTCATGCGC AGGGTGGCGGGGGACGAGCTCACCGGGGTCTGCTACGTGGGCAGCATGGACGTCAACGCG CTCACCGGCTTCGTGCTCATTCCCCTGGCCTGCTACCTGGTCATCGGCACGTCCTTCATC CTCTCGGGCTTCGTGGCCCTGTTCCACATCCGGAGGGTGATGAAGACGGGCGGCGAGAAC ACGGACAAGCTGGAGAAGCTCATGGTGCGTATCGGGCTCTTCTCTGTGCTGTACACCGTG CCGGCCACCTGTGTGATCGCCTGCTACTTTTACGAACGCCTCAACATGGATTACTGGAAG ATCCTGGCGGCGCAGCACAAGTGCAAAATGAACAACCAGACTAAAACGCTGGACTGCCTG ATGGCCGCCTCCATCCCCGCCGTGGAGATCTTCATGGTGAAGATCTTTATGCTGCTGGTG GTGGGGATCACCAGCGGGATGTGGATTTGGACCTCCAAGACTCTGCAGTCCTGGCAGCAG GTGTGCAGCCGTAGGTTAAAGAAGAAGAGCCGGAGAAAACCGGCCAGCGTGATCACCAGC GGTGGGATTTACAAAAAAGCCCAGCATCCCCAGAAAACTCACCACGGGAAATATGAGATC CCTGCCCAGTCGCCCACCTGCGTGTGAACAGGGCTGGAGGGAAGGGCACAGGGGCGCCCG GAGCTAAGATGTGGTGCTTTTCTTGGTTGTGTTTTTCTTTCTTCTTCTTCTTTTTTTTTT TTTATAAAAGCAAAAGAGAAATACATAAAAAAGTGTTTACCCTGAAATTCAGGATGCTGT GATACACTGAAAGGAAAAATGTACTTAAAGGGTTTTGTTTTGTTTTGGTTTTCCAGCGAA GGGAAGCTCCTCCAGTGAAGTAGCCTCTTGTGTAACTAATTTGTGGTAAAGTAGTTGATT CAGCCCTCAGAAGAAAACTTTTGTTTAGAGCCCTCCGTAAATATACATCTGTGTATTTGA GTTGGCTTTGCTACCCATTTACAAATAAGAGGACAGATAACTGCTTTGCAAATTCAAGAG CCTCCCCTGGGTTAACAAATGAGCCATCCCCAGGGCCCACCCCCAGGAAGGCCACAGTGC TGGGCGGCATCCCTGCAGAGGAAAGACAGGACCCGGGGCCCGCCTCACACCCCAGTGGAT TTGGAGTTGCTTAAAATAGACTCTGGCCTTCACCAATAGTCTCTCTGCAAGACAGAAACC TCCATCAAACCTCACATTTGTGAACTCAAACGATGTGCAATACATTTTTTTCTCTTTCCT TGAAAATAAAAAGAGAAACAAGTATTTTGCTATATATAAAGACAACAAAAGAAATCTCCT AACAAAAGAACTAAGAGGCCCAGCCCTCAGAAACCTTTCAGTGCTACATTTTGTGGCTTT TTAATGGAAACCAAGCCAATGTTATAGACCTTTGGACTGATTTGTGGAAAGGAGGGGGGA AGAGGGAGAAGGATCATTCAAAAGTTACCCAAAGGGCTTATTGACTCTTTCTATTGTTAA ACAAATGATTTCCACAAACAGATCAGGAAGCACTAGGTTGGCAGAGACACTTTGTCTAGT GTATTCTCTTCACAGTGCCAGGAAAGAGTGGTTTCTGCGTGTGTATATTTGTAATATATG ATATTTTTCATGCTCCACTATTTTATTAAAAATAAAATATGTTCTTTAAAAAAAAAAAAA AAAAACTCGAC >OriGene 5' read for NM_007197 unedited
CGGTTTTTTATTTTTTCCGCCGGNCCCGTTCAGATTTGTATACGACTCATATAGGCGGCC GCGNAATTCGCACGAGCCAGGCCGGGCGGGCATGGGCGGGGGCCCGAGCAGGGTGGAGAG CCGGGGCCAGCAGCAGCCCGTGCCCGGGAGCGGCGGCGCTGAGGGGCGCGGAGCTCCCCG CGAGGACACGTCCAACGCCAGCATGCAGCGCCCGGGCCCCCGCCTGTGGCTGGTCCTGCA GGTGATGGGCTCGTGCGCCGCCATCAGCTCCATGGACATGGAGCGCCCGGGCGACGGCAA ATGCCAGCCCATCGAGATCCCGATGTGCAAGGACATCGGCTACAACATGACTCGTATGCC CAACCTGATGGGCCACGAGAACCAGCGCGAGGCAGCCATCCAGTTGCACGAGTTCGCGCC GCTGGTGGAGTACGGCTGCCACGGCCACCTCCGCTTCTTCCTGTGCTCGCTGTACGCGCC GATGTGCACCGAGCAGGTCTCTACCCCCATCCCCGCCTGCCGGGTCATGTGCGAGCAGGC CCGGCTCAAGTGCTCCCCGATTATGGAGCAGTTCAACTTCAAGTGGCCCGACTCCCTGGA CTGCCGGNAACTCCCCACAAGAACGACCCCAACTACCTGTGCATGGAGGCGCCCAACACG GCTCGGACGAGCCCACCCGGNGCTCGGGCCTGTCCCCGCCGCTGTTCCGGCGCAGCGGCC CACAGCGCGCAGGACACCCGCTGAAGGACGGGGGCCCGGNCGCGGCGGCTGCAACAACCC GGNNCAGTCCACCACGTGAGAAAACGCGTGTGCGCCCGCTCTGCCGCCCCGGGTGGCAGT GTACTGGAGCCGCNAGGACAAGCGCTTCCAATGGTCTGCCTGGCCTCTGGCCGGGGCTGG GTTTTTTTTCAGCGCTTACACGGGTTACCTTCTTATGAACCGGCCCGTTTCGGTACCCGA GGGCCCANATNTTCCTTTCAGGGCTATGCGGTAACGCGGGGGTACCTCC >OriGene 3' read for NM_007197 unedited
TCTTTATGNNACCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTAAAGACA TATTTTATTTTTAATAAAATAGTGGAGCATGAAAAAATCATATATTACAAATATACACAC GCAGAAACCACTCTTTCCTGGCACTGTGAAGAGAATACACTAGACAAAGTGTCTCTGCCA ACCTAGTGCTTCCTGATCTGTTTGTGGAAATCATTTGTTTAACAATAGAAAGAGTCAATA AGCCCTTTGGGTAACTTTTGAATGATCCTTCTCCCTCTTCCCCCCTCCTTTCCACAAATC AGTCCAAAGGTCTATAACATTGGCTTGGTTTCCATTAAAAAGCCACAAAATGTAGCACTG AAAGGTTTCTGAGGGCTGGGCCTCTTAGTTCTTTTGTTAGGAGATTTCTTTTGTTGTCTT TATATATAGCAAAATACTTGTTTCTCTTTTTATTTTCAAGGAAAGAGAAAAAAATGTATT GCACATCGTTTGAGTTCACAAATGTGAGGTTTGATGGAGGTTTCTGTCTTGCAGAGAGAC TATTGGTGAAGGCCAGAGTCTATTTTAAGCAACTCCAAATCCACTGGGGTGTGAGGCGGG CCCCGGGTCCTGTCTTTCCTCTGCAGGGATGCCGNCCAGCACTGTGGCCTTCCTGGGGGG TGGGCCTGGGATGGCTCATTTGTTAACCCNAGGGGAGCTCTTGAATTTGAAAGCAGTTAT CTGTCCTCTTATTTGAAATGGGTAGCAAAGCCAACTCAAAACACAGATGTATATTTACCG AGGGCTCAAACAAAAGTTTTCTTCTGAGGGCTGGATCAACTACTTTACCACAAATAGTTA CACAGAGGCTACTCACTGGGAGAGCTTCCCTCGCTGAAAACCAAACAAACAAACCCNTTA GACATTTTCCTTTCATGTTCACAGCTCTGATTTCAGGTAACCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007197 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007197.2, NP_009128.1 |
| RefSeq Size | 3260 bp |
| RefSeq ORF | 1746 bp |
| Locus ID | 11211 |
| UniProt ID | Q9ULW2 |
| Domains | FRI, Frizzled |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway |
| Gene Summary | This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families
,null,
The FASEB Journal
,PubMed ID 28733458
[FZD10]
|
|
R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6
,ME Binnerts, KA Kim, JM Bright, SM Patel, K Tran, M Zhou, JM Leung, Y Liu, WE Lomas 3rd, M Dixon, SA Hazell, M Wagle, WS Nie, N Tomasevic, J Williams, X Zhan, MD Levy, WD Funk, and A Abo,
Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14700-5.
[FZD10]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209717 | FZD10 (Myc-DDK-tagged)-Human frizzled family receptor 10 (FZD10) |
CNY 6,488.00 |
|
| RC209717L1 | Lenti ORF clone of Human frizzled family receptor 10 (FZD10), Myc-DDK-tagged |
CNY 8,888.00 |
|
| RC209717L2 | Lenti ORF clone of Human frizzled family receptor 10 (FZD10), mGFP tagged |
CNY 5,890.00 |
|
| RC209717L3 | Lenti ORF clone of Human frizzled family receptor 10 (FZD10), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC209717L4 | Lenti ORF clone of Human frizzled family receptor 10 (FZD10), mGFP tagged |
CNY 5,890.00 |
|
| RG209717 | FZD10 (tGFP-tagged) - Human frizzled family receptor 10 (FZD10) |
CNY 8,088.00 |
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