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C2 (NM_000063) Human Untagged Clone
CAT＃: SC115664
C2 (untagged)-Human complement component 2 (C2), transcript variant 1
CNY 5,512.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARMD14; CO2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115664 sequence for NM_000063 edited (data generated by NextGen Sequencing)
ATGGGCCCACTGATGGTTCTTTTTTGCCTGCTGTTCCTGTACCCAGGTCTGGCAGACTCG GCTCCCTCCTGCCCTCAGAACGTGAATATCTCGGGTGGCACCTTCACCCTCAGCCATGGC TGGGCTCCTGGGAGCCTTCTCACCTACTCCTGCCCCCAGGGCCTGTACCCATCCCCAGCA TCACGGCTGTGCAAGAGCAGCGGACAGTGGCAGACCCCAGGAGCCACCCGGTCTCTGTCT AAGGCGGTCTGCAAACCTGTGCGCTGTCCAGCCCCTGTCTCCTTTGAGAATGGCATTTAT ACCCCACGGCTGGGGTCCTATCCCGTGGGTGGCAATGTGAGCTTCGAGTGTGAGGATGGC TTCATATTGCGGGGCTCGCCTGTGCGTCAGTGTCGCCCCAACGGCATGTGGGATGGAGAA ACAGCTGTGTGTGATAATGGGGCTGGCCACTGCCCCAACCCAGGCATTTCACTGGGCGCA GTGCGGACAGGCTTCCGCTTTGGTCATGGGGACAAGGTCCGCTATCGCTGCTCCTCGAAT CTTGTGCTCACGGGGTCTTCGGAGCGGGAGTGCCAGGGCAACGGGGTCTGGAGTGGAACG GAGCCCATCTGCCGCCAACCCTACTCTTATGACTTCCCTGAGGACGTGGCCCCTGCCCTG GGCACTTCCTTCTCCCACATGCTTGGGGCCACCAATCCCACCCAGAAGACAAAGGAAAGC CTGGGCCGTAAAATCCAAATCCAGCGCTCTGGTCATCTGAACCTCTACCTGCTCCTGGAC TGTTCGCAGAGTGTGTCGGAAAATGACTTTCTCATCTTCAAGGAGAGCGCCTCCCTCATG GTGGACAGGATCTTCAGCTTTGAGATCAATGTGAGCGTTGCCATTATCACCTTTGCCTCA GAGCCCAAAGTCCTCATGTCTGTCCTGAACGACAACTCCCGGGATATGACTGAGGTGATC AGCAGCCTGGAAAATGCCAACTATAAAGATCATGAAAATGGAACTGGGACTAACACCTAT GCGGCCTTAAACAGTGTCTATCTCATGATGAACAACCAAATGCGACTCCTCGGCATGGAA ACGATGGCCTGGCAGGAAATCCGACATGCCATCATCCTTCTGACAGATGGAAAGTCCAAT ATGGGTGGCTCTCCCAAGACAGCTGTTGACCATATCAGAGAGATCCTGAACATCAACCAG AAGAGGAATGACTATCTGGACATCTATGCCATCGGGGTGGGCAAGCTGGATGTGGACTGG AGAGAACTGAATGAGCTAGGGTCCAAGAAGGATGGTGAGAGGCATGCCTTCATTCTGCAG GACACAAAGGCTCTGCACCAGGTCTTTGAACATATGCTGGATGTCTCCAAGCTCACAGAC ACCATCTGCGGGGTGGGGAACATGTCAGCAAACGCCTCTGACCAGGAGAGGACACCCTGG CATGTCACTATTAAGCCCAAGAGCCAAGAGACCTGCCGGGGGGCCCTCATCTCCGACCAA TGGGTCCTGACAGCAGCTCATTGCTTCCGCGATGGCAACGACCACTCCCTGTGGAGGGTC AATGTGGGAGACCCCAAATCCCAGTGGGGCAAAGAATTCCTTATTGAGAAGGCGGTGATC TCCCCAGGGTTTGATGTCTTTGCCAAAAAGAACCAGGGAATCCTGGAGTTCTATGGTGAT GACATAGCTCTGCTGAAGCTGGCCCAGAAAGTAAAGATGTCCACCCATGCCAGGCCCATC TGCCTTCCCTGCACGATGGAGGCCAATCTGGCTCTGCGGAGACCTCAAGGCAGCACCTGT AGGGACCATGAGAATGAACTGCTGAACAAACAGAGTGTTCCTGCTCATTTTGTCGCCTTG AATGGGAGCAAACTGAACATTAACCTTAAGATGGGAGTGGAGTGGACAAGCTGTGCCGAG GTTGTCTCCCAAGAAAAAACCATGTTCCCCAACTTGACAGATGTCAGGGAGGTGGTGACA GACCAGTTCCTATGCAGTGGGACCCAGGAGGATGAGAGTCCCTGCAAGGGAGAATCTGGG GGAGCAGTTTTCCTTGAGCGGAGATTCAGGTTTTTTCAGGTGGGTCTGGTGAGCTGGGGT CTTTACAACCCCTGCCTTGGCTCTGCTGACAAAAACTCCCGCAAAAGGGCCCCTCGTAGC AAGGTCCCGCCGCCACGAGACTTTCACATCAATCTCTTCCGCATGCAGCCCTGGCTGAGG CAGCACCTGGGGGATGTCCTGAATTTTTTACCCCTCTAG Clone variation with respect to NM_000063.4 >OriGene 5' read for NM_000063 unedited
NGTTCGAATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGCTAACANAAG ACCATCCCCCTTGCCACTCCCTGGTTTTTCTTCTCTGGCAGCAATGAAGCAGCTGCTGAC CCAGCTCTAGTTTTCGGGAAGTCAGATGACCTTTTCCCTCCCGCGGCTCTCTACCTCTCG CCGCCCCTAGGGAGGACACCATGGGCCCACTGATGGTTCTTTTTTGCCTGCTGTTCCTGT ACCCAGGTCTGGCAGACTCGGCTCCCTCCTGCCCTCAGAACGTGAATATCTCGGGTGGCA CCTTCACCCTCAGCCATGGCTGGGCTCCTGGGAGCCTTCTCACCTACTCCTGCCCCCAGG GCCTGTACCCATCCCCAGCATCACGGCTGTGCAAGAGCAGCGGACAGTGGCAGACCCCAG GAGCCACCCGGTCTCTGTCTAAGGCGGTCTGCAAACCTGTGCGCTGTCCAGCCCCTGTCT CCTTTGAGAATGGCATTTATACCCCACGGCTGGGGTCCTATCCCGTGGGTGGCAATGTGA GCTTCGAGTGTGAGGATGGCTTCATATTGCGGGGCTCGCCTGTGCGTCAGTGTCGCCCCA ACGGCATGTGGGATGGAGAAACAGCTGTGTGTGATAATGGGGCTGGCCACTGCCCCAACC CAGGCATTTCACTGGGCGCAGTGCGGACAGGCTTCCGCTNTGGTCATGGGGACAAGGTCC GCTATCGCTGCTCCTCGAATCTTGTGCTCACGGNGTCTTCGGAGCGGNAGTGCCAGGGCA ACGGGGTCTGGAGTGGAACGGAGCCCATCTGCCGNCAACCCTACTCTTATGACTTNCCTG NAGGACGTGGGCCCTGNCCTGGGCACTTNCTTCTCCCACATGCTGGNNGCCACCATCCCA CCCAAAGACAAAGGAAAGCT >OriGene 3' read for NM_000063 unedited
CCCCCATTCCTTGCCCGCGGCCGCAATCTACAGTCGACTTTTTTTTTTTTTTTTTTTGTG GAAACCATTGATTTTTATTAATTTCATAACTGGGAAATTCCATGTGAAAGTGAAACAAGC ATGAGTCAAGTCAACCAGGGAAGGAATCTGGGGACAGGCCACGGAGCGGGAGGTGGGGCA GCGAGGCAGTCCTGCTGGTAGGAGCCCTGAGGATTTCCCAGCTTGTGTGCGCTGCCTCTG GCATCCTAGAGACCCGGATTTACTCAGCTAGGAGAGAGGATGGATCACAGGGTCTAAGGG TGGCCATTCAGAGGTAGAAGATGGAGGGGCGGCAGATTCTGGCAGGGCAGCAGAGGGCTC AGTGGCCATGGCTAGAGGGGTAAAAAATTCAGGACATCCCCCAGGTGCTGCCTCAGCCAG GGCTGCATGCGGAAGAGATTGATGTGAAAGTCTCGTGGCGGCGGGACCTTGCTACGAGGG GCCCTTTTGCGGGAGTTTTTGTCAGCAGAGCCCAGGCAGGGGTTGTAAAGACCCCAGCTC ACCAGACCCACCTGACAAAACCTGAATCTCCGATCAAGGAAAACTGCTCCCCCAGATTCT CCCTTGCAGGGACTCTCATCCTCCTGGGTCCCACTGCATAGGAACTGGCCCGCCACCACC TCCCTGACATCTGTCAAGCTGGGCGAACACGGCCTCTTTTTTTTCTAGACTCCCTCGGCC CAAGCTTCGTCACCATCCTTCCCCTCCTCAGGGCCCCGCCTACACCTTGTCCCAATTCCG CCCCCTCCCCTCCATCCCTACATCTCTTCCCTCACACACCCCCTTCATCCCCCACCCCTC CTCCCCCCCTCTCCCCGCTCATCACTGCCCCTTCCCCTGTCGCCGCTCTCTCCCCCCCCC CTCCGCCGCCCCCACCCCCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000063 |
| Insert Size | 2740 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000063.3, NP_000054.2 |
| RefSeq Size | 2609 bp |
| RefSeq ORF | 2259 bp |
| Locus ID | 717 |
| UniProt ID | P06681 |
| Domains | CCP, Tryp_SPc, VWA |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades, Systemic lupus erythematosus |
| Gene Summary | Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208097 | C2 (Myc-DDK-tagged)-Human complement component 2 (C2), transcript variant 1 |
CNY 5,512.00 |
|
| RC208097L1 | Lenti ORF clone of Human complement component 2 (C2), transcript variant 1, Myc-DDK-tagged |
CNY 7,912.00 |
|
| RC208097L2 | Lenti ORF clone of Human complement component 2 (C2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC208097L3 | Lenti ORF clone of Human complement component 2 (C2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208097L4 | Lenti ORF clone of Human complement component 2 (C2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG208097 | C2 (tGFP-tagged) - Human complement component 2 (C2), transcript variant 1 |
CNY 7,112.00 |
