TPX2 (NM_012112) Human Untagged Clone

Name: TPX2 (NM_012112) Human Untagged Clone
SKU: SC115515
Price: 5480.00

CAT＃: SC115515

TPX2 (untagged)-Human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2)

Datasheet

SDS

"NM_012112" in other vectors (6)

CNY 5,480.00

货期*

现货

规格

Cited in 1 publication.

Product images

经常一起买 (4)

TA382768

TPX2 Rabbit polyclonal Antibody

CNY 1,999.00
CNY 3,280.00

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TF81001

TurboFectin Transfection Reagent (1 mL in 1 vial)

CNY 4,090.00

CC100003

DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)

CNY 1,280.00

PRIMER

Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each

CNY 480.00

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	C20orf1; C20orf2; DIL-2; DIL2; FLS353; GD:C20orf1; HCA519; HCTP4; p100; REPP86
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for NM_012112 edited GAATTCGGCACGAGGGCGAGGCTAGGTGAGCCGTGGGAAGAAAAGAGGGAGCAGCTAGGG CGCGGGTCTCCCTCCTCCCGGAGTTTGGAACGGCTGAAGTTCACCTTCCAGCCCCTAGCG CCGTTCGCGCCGCTAGGCCTGGCTTCTGAGGCGGTTGCGGTGCTCGGTCGCCGCCTAGGC GGGGCAGGGTGCGAGCAGGGGCTTCGGGCCACGCTTCTCTTGGCGACAGGATTTTGCTGT GAAGTCCGTCCGGGAAACGGAGGAAAAAAAGAGTTGCGGGAGGCTGTCGGCTAATAACGG TTCTTGATACATATTTGCCAGACTTCAAGATTTCAGAAAAGGGGTGAAAGAGAAGATTGC AACTTTGAGTCAGACCTGTAGGCCTGATAGACTGATTAAACCACAGAAGGTGACCTGCTG AGAAAAGTGGTACAAATACTGGGAAAAACCTGCTCTTCTGCGTTAAGTGGGAGACAATGT CACAAGTTAAAAGCTCTTATTCCTATGATGCCCCCTCGGATTTCATCAATTTTTCATCCT TGGATGATGAAGGAGATACTCAAAACATAGATTCATGGTTTGAGGAGAAGGCCAATTTGG AGAATAAGTTACTGGGGAAGAATGGAACTGGAGGGCTTTTTCAGGGCAAAACTCCTTTGA GAAAGGCTAATCTTCAGCAAGCTATTGTCACACCTTTGAAACCAGTTGACAACACTTACT ACAAAGAGGCAGAAAAAGAAAATCTTGTGGAACAATCCATTCCGTCAAATGCTTGTTCTT CCCTGGAAGTTGAGGCAGCCATATCAAGAAAAACTCCAGCCCAGCCTCAGAGAAGATCTC TTAGGCTTTCTGCTCAGAAGGATTTGGAACAGAAAGAAAAGCATCATGTAAAAATGAAAG CCAAGAGATGTGCCACTCCTGTAATCATCGATGAAATTCTACCCTCTAAGAAAATGAAAG TTTCTAACAACAAAAAGAAGCCAGAGGAAGAAGGCAGTGCTCATCAAGATACTGCTGAAA AGAATGCATCTTCCCCAGAGAAAGCCAAGGGTAGACATACTGTGCCTTGTATGCCACCTG CAAAGCAGAAGTTTCTAAAAAGTACTGAGGAGCAAGAGCTGGAGAAGAGTATGAAAATGC AGCAAGAGGTGGTGGAGATGCGGAAAAAGAATGAAGAATTCAAGAAACTTGCTCTGGCTG GAATAGGGCAACCTGTGAAGAAATCAGTGAGCCAGGTCACCAAATCAGTTGACTTCCACT TCCGCACAGATGAGCGAATCAAACAACATCCTAAGAACCAGGAGGAATATAAGGAAGTGA ACTTTACATCTGAACTACGAAAGCATCCTTCATCTCCTGCCCGAGTGACTAAGGGATGTA CCATTGTTAAGCCTTTCAACCTGTCCCAAGGAAAGAAAAGAACATTTGATGAAACAGTTT CTACATATGTGCCCCTTGCACAGCAAGTTGAAGACTTCCATAAACGAACCCCTAACAGAT ATCATTTGAGGAGCAAGAAGGATGATATTAACCTGTTACCCTCCAAATCTTCTGTGACCA AGATTTGCAGAGACCCACAGACTCCTGTACTGCAAACCAAACACCGTGCACGGGCTGTGA CCTGCAAAAGTACAGCAGAGCTGGAGGCTGAGGAGCTCGAGAAATTGCAACAATACAAAT TCAAAGCACGTGAACTTGATCCCAGAATACTTGAAGGTGGGCCCATCTTGCCCAAGAAAC CACCTGTGAAACCACCCACCGAGCCTATTGGCTTTGATTTGGAAATTGAGAAAAGAATCC AGGAGCGAGAATCAAAGAAGAAAACAGAGGATGAACACTTTGAATTTCATTCCAGACCTT GCCCTACTAAGATTTTGGAAGATGTTGTGGGTGTTCCTGAAAAGAAGGTACTTCCAATCA CCGTCCCCAAGTCACCAGCCTTTGCATTGAAGAACAGAATTCGAATGCCCACCAAAGAAG ATGAGGAAGAGGACGAACCGGTAGTGATAAAAGCTCAACCTGTGCCACATTATGGGGTGC CTTTTAAGCCCCAAATCCCAGAGGCAAGAACTGTGGAAATATGCCCTTTCTCGTTTGATT CTCGAGACAAAGAACGTCAGTTACAGAAGGAGAAGAAAATAAAAGAACTGCAGAAAGGGG AGGTGCCCAAGTTCAAGGCACTTCCCTTGCCTCATTTTGACACCATTAACCTGCCAGAGA AGAAGGTAAAGAATGTGACCCAGATTGAACCTTTCTGCTTGGAGACTGACAGAAGAGGTG CTCTGAAGGCACAGACTTGGAAGCACCAGCTGGAAGAAGAACTGAGACAGCAGAAAGAAG CAGCTTGTTTCAAGGCTCGTCCAAACACCGTCATCTCTCAGGAGCCCTTTGTTCCCAAGA AAGAGAAGAAATCAGTTGCTGAGGGCCTTTCTGGTTCTCTAGTTCAGGAACCTTTTCAGC TGGCTACTGAGAAGAGAGCCAAAGAGCGGCAGGAGCTGGAGAAGAGAATGGCTGAGGTAG AAGCCCAGAAAGCCCAGCAGTTGGAGGAGGCCAGACTACAGGAGGAAGAGCAGAAAAAAG AGGAGCTGGCCAGGCTACGGAGAGAACTGGTGCATAAGGCAAATCCAATACGCAAGTACC AGGGTCTGGAGATAAAGTCAAGTGACCAGCCTCTGACTGTGCCTGTATCTCCCAAATTCT CCACTCGATTCCACTGCTAAACTCAGCTGTGAGCTGCGGATACCGCCCGGCAATGGGACC TGCTCTTAACCTCAAACCTAGGACCGTCTTGCTTTGTCATTGGGCATGGAGAGAACCCAT TTCTCCAGACTTTTACCTACCCGTGCCTGAGAAAGCATACTTGACAACTGTGGACTCCAG TTTTGTTGAGAATTGTTTTCTTACATTACTAAGGCTAATAATGAGATGTAACTCATGAAT GTCTCGATTAGACTCCATGTAGTTACTTCCTTTAAACCATCAGCCGGCCTTTTATATGGG TCTTCACTCTGACTAGAATTTAGTCTCTGTGTCAGCACAGTGTAATCTCTATTGCTATTG CCCCTTACGACTCTCACCCTCTCCCCACTTTTTTTAAAAATTTTAACCAGAAAATAAAGA TAGTTAAATCCTAAGATAGAGATTAAGTCATGGTTTAAATGAGGAACAATCAGTAAATCA GATTCTGTCCTCTTCTCTGCATACCGTGAATTTATAGTTAAGGATCCCTTTGCTGTGAGG GTAGAAAACCTCACCAACTGCACCAGTGAGGAAGAAGACTGCGTGGATTCATGGGGAGCC TCACAGCAGCCACGTAGCAGGCTCTGGGTGGGGCTGCCGTTAAGGCACGTTCTTTCCTTA CTGGTGCTGATAACAACAGGGAACCGTGCAGTGTGCATTTTAAGACCTGGCCTGGAATAA ATACGTTTTGTCTTTCCCTCAAAAAAAAAAAAAAAAAACTCGAC 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for NM_012112 unedited GAAGCACTTCGGATTTGTAAACCCGNATTCACTATNAGGGCGGACGCCAATTCGGCACGA GGGCGAGGCTAGGTGAGCCGTGGGAAGAAAAGAGGAGCAGCTAGGGCGCGGGTCTCCCTC CTCCCGGAGTTTGGAACGGCTGAAGTTCACCTTCCAGCCCCTAGCGCCGTTCGCGCCGCT AGGCCTGGCTTCTGAGGCGGTTGCGGTGCTCGGTCGCCTTTTATGCGGGGCAGGGTGCGA GCAGGGGCTTCGGGCCACGCTTCTCTTGGCGACAGGATTTTGCTGTGAAGTCCGTCCGGG AAACGGAGGAAAAAAAGAGTTGCGGGAGGCTGTCGGCTAATAACGGTTCTTGATACATAT TTGCCAGACTTCAAGATTTCAGAAAAGGGGTGAAAGAGAAGATTGCAACTTTGAGTCAGA CCTGTAGGCCTGATAGACTGATTAAACCACAGAAGGTGACCTGCTGAGAAAAGTGGTACA AATACTGGGAAAAACCTGCTCTTCTGCGTTAAGTGGGAGACAATGTCACAAGTTAAAAGC TCTTATTCCTATGATGCCCCCTCGGATTTCATCAATTTTTCATCCTTGGATGATGAAGGA GATACTCAAAACATAGATTCATGGTTTGAGGAGAAGGCCAATTTGGAGAATAAGTTACTG GGGAAGAATGGAACTGGAGGGCTTTTTCAGGGCAAAACTCCTTTGAGAAAGGCTAATCTT CAGCAAGCTATTGTCACACCTTTGAAACCAGTTGANCACACTTACTACAAAGAGGCAGAA AAAGAAAATCTTGTGGAACAATCCATTCCGTCAAATGCTTGTTCTTCCCTGGAAGTTTGA GCAGCCATATCAAGANAACTCCAGCCCAGCCTCAGAAN 3' Read Nucleotide Sequence (showhide) >OriGene 3' read for NM_012112 unedited CAGTGNAGATCGAGTTTTTTTTTTTTTTTTTTGAGGGAAAGACAAACGTATTTATTCCAG GCCAGGTCTTAAAATGCACACTGCACGGTTCCCTGTTGTTATCAGCACCAGTAAGGAAAG AACGTGCCTTAACGGCAGCCCCACCCAGAGCCTGCTACGTGGCTGCTGTGAGGCTCCCCA TGAATCCACGCAGTCTTCTTTCTCACTGGTGCAGTTGGTGAGGTTTTCTACCCTCACAGC AAAGGGATCCTTAACTATAAATTCACGGTATGCAGAGAAGAGGACAGAATCTGATTTACT GATTGTTCCTCATTTAAACCATGACTTAATCTCTATCTTAGGATTTAACTATCTTTATTT TCTGGTTAAAATTTTTAAAAAAAGTGGGGAGAGGGTGAGAGTCGTAAGGGGCAATAGCAA TAGAGATTACACTGTGCTGACACAGAGACTAAATTCTAGTCAGAGTGAAGACCCATATAA AAGGCCGGCTGATGGTTTAAAGGAAGTAACTACATGGAGTCTAATCGAGACATTCATGAG TTACATCTCATTATTAGCCTTAGTAATGTAAGAAAACAATTCTCAACAAAACTGGAGTCC ACAGTTGTCAAGTATGCTTTCTCAGGCACGGGTAGGTAAAAGTCTGGAGAAATGGGTTCT CTCCATGCCCAATGACAAAGCAAGACGGTCCTANGTTTGAGGTTAAGAGCANGTCCCATT GCCGGGCGGTATCCGCAGCTCACAGCTGAGTTACCAGTGAATCGAGTGGAGATTTGGGAG AACAGGACAGTCAGAGCTGTCACTTGACTTATCTCCAACCCTGTACTTGCCATTGGATTG CCTATGCACAGTTTTCTCGTAGCTGGCAGCTCTCTTTTCTGCCTCCTCCGGAGCGGCCTC CCACTGCTGGCTTTTGGCTTTACTAACAATTTTTTCAGTCTGCGGTTTGGTTTTTTAANA CCATGAAAGTCCGACCAAAAAA
Restriction Sites	NotI-NotI
ACCN	NM_012112
Insert Size	3460 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_012112.4, NP_036244.2
RefSeq Size	3685 bp
RefSeq ORF	2244 bp
Locus ID	22974
UniProt ID	Q9ULW0
Protein Families	Druggable Genome, Stem cell - Pluripotency
Gene Summary	Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation (PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin-alpha (PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940).[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

The use of this cDNA Clones has been cited in the following citations:
Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development ,Vargas-Hurtado, D;Brault, JB;Piolot, T;Leconte, L;Da Silva, N;Pennetier, C;Baffet, A;Marthiens, V;Basto, R;, Curr. Biol. ,PubMed ID 31495584 [TPX2]

Documents

Product Manuals
TrueORFs: Open Reading Frame Clones - 10 ug in PrecisionShuttle Vector System pLenti-ORF destination vector Transfection - TurboFectin 8.0 Transfection Reagent Plasmid Preparation - PowerPrep Plasmid Purification Kits
FAQs
TrueORF Clones/PrecisionShuttle Organelle Marker Transfection Reagent
SDS
TrueORF SDS

Resources

cDNA 克隆相关资源
Video Tutorial: Clone Selection Guide Product Video: What is TrueORF GOLD and why it is the most popular type of clone Video Tutorial: How to make Lentivirus particles Video Tutorial: Is the Lentivirus Safe Product Brochure: cDNA clones $98 Clones. Download the List of 15,000 Protocol: Lentivirus packaging

Other Versions

SKU	Description	Size	Price
RC205821	TPX2 (Myc-DDK-tagged)-Human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2)	10 ug 产品选项验证失败所有选项都是必需的	CNY 5,472.00 CNY 5,800.00
RC205821L1	Lenti ORF clone of Human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2), Myc-DDK-tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 7,872.00
RC205821L2	Lenti ORF clone of Human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2), mGFP tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 7,700.00
RC205821L3	Lenti ORF clone of Human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2), Myc-DDK-tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 7,700.00
RC205821L4	Lenti ORF clone of Human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2), mGFP tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 7,872.00
RG205821	TPX2 (tGFP-tagged) - Human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2)	10 ug 产品选项验证失败所有选项都是必需的	CNY 7,072.00

其它TPX2产品

Expression Plasmids

Lentiviral Particles

CRISPR

RNAi

Proteins

Antibodies