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RAB10 (NM_016131) Human Untagged Clone
CAT＃: SC114472
RAB10 (untagged)-Human RAB10, member RAS oncogene family (RAB10)
CNY 3,600.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114472 sequence for NM_016131 edited (data generated by NextGen Sequencing)
ATGGCGAAGAAGACGTACGACCTGCTTTTCAAGCTGCTCCTGATCGGGGATTCCGGAGTG GGGAAGACCTGCGTCCTTTTTCGTTTTTCGGATGATGCCTTCAATACTACCTTTATTTCC ACCATAGGAATAGACTTCAAGATCAAAACAGTTGAATTACAAGGAAAGAAGATCAAGCTA CAGATATGGGATACAGCAGGCCAGGAGCGATTTCACACCATCACAACCTCCTACTACAGA GGCGCAATGGGTATCATGCTAGTATATGACATCACCAATGGTAAAAGTTTTGAAAACATC AGCAAATGGCTTAGAAACATAGATGAGCATGCCAATGAAGATGTGGAAAGAATGTTACTA GGAAACAAGTGTGATATGGACGACAAAAGAGTTGTACCTAAAGGAAAAGGAGAACAGATT GCAAGGGAGCATGGTATTAGGTTTTTTGAGACTAGTGCAAAAGCAAATATAAACATCGAA AAGGCGTTCCTCACGTTAGCTGAAGATATCCTTCGAAAGACCCCTGTAAAAGAGCCCAAC AGTGAAAATGTAGATATCAGCAGTGGAGGAGGCGTGACAGGCTGGAAGAGCAAATGCTGC TGA Clone variation with respect to NM_016131.4 >OriGene 5' read for NM_016131 unedited
TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGGGGCTATGTAAC TGAGCTCGTCGACTTAGGGGTCCTTCTTCGCTGCCCTCGCCGCGTGCTAGCAGGGAGTTT CCGCTCGGGAGAGAGACTGTCCTCACGCCCGCTGCGCCTCCTCGACGGCAGAGCAGGCTT GCTCGCCCGTGGGAGCGTCCCGGCCGAGAAGCCCTGAGGGGGGAGGGGAGGCCATTTTGT CCCGACCGACTCCCCGGAACCGGGCGGAGCGGCTGGGAGAGGCTGCGGAGCCGCGGTCGC CGCCCTCGGAGGCACTGGACGCCGCCACTGTCGGGGCTTCCTCAAAGCTGTTCGTAGGTC GCCCGCGCCGTCTCGAGCCTTTTTCCCACGCTTCCCCGGTCCTCCGGCCTGAGAACGCCC GAGTGAGGAGTTGGCCGTAGTGAGAGGGACCGATCCCTTGGGGCCGCCGGCGGCGAGAGC CCGAGCCGCTCCTCCCAATGGCGAAGAAGACGTACGACCTGCTTTTCAAGCTGCTCCTGA TCGGGGATTCCGGAGTGGGGAAGACCTGCGTCCTTTTTCGTTTTTCGGATGATGCCTTCA ATACTACCTTTATTTCCACCATAGGAATAGACTTCAAGATCAAAACAGTTGAATTACAAG GAAAGAAGATCAAGCTACAGATATGGGATACAGCAGGCCAGGAGCGATTTCACACCATCA CAACCTCCTACTACAGAGGCGCAATGGGTATCATGCTAGTATATGACATCACCATGGGTT AAAAGTTTTGAAACATCAGNCAATGGCTTAGAACATAGATGAGCATGCCATGNAAGATGT GGNAAAGAATGTTACTANGAAACAGTGTGATATGGACACAANAGNAGTGTACTAAAGGAA AGGAAACAGATGCAGGGACC >OriGene 3' read for NM_016131 unedited
CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAAAAATTTCAGTTTATT TAAATTGTTAAGTAGAATATGAAACCGAATTTGTAGCTAGTACCAGAGAATGGACTTAAC TGTTTGGTGTTTAATGAGAACAGCTTCTACACAGGATCCCAAGAGACTTACAGAAAAGGG GCAAAGCCCTAATATTAAGCAAATAAAACTCATGTTTCAAACAGATTATACAAAAATTGA TTTATACTTCATTTCCCTTTTTTGATATTTAGAAAGTGCAGATTTAACAAAAGGTAGCCA TATCCTTTCTATGTACAATGCCGATTATAATTATGCAAAACTGTCAGTCTGTTATCCAAA AATCCCAGTGTTTAGCTCTCCAACCTTAAGTCATGGAATTGAATAAGAATTAAAGAGGGT TAAAATAAAAAAGCTAATGCCACATTCCAGATAAAGGGAAGCAACAAATACATTAATCTA ACAACAGTAGGTTTAACCTAAACTTTTCAAAAAGCTTAACATCATTTCATTATATTTTTA GTGGAAAATTAGGGATTATTTGGCAATGCTGCTTTTTACTAGTAGTAAACAATGATAAAG TCAAGTGTGGGAATAACCTAAGAATAACAACCAGTGAGGCATATAAAATTGTTTTTAGGG CACTATCTGAAAAATTTGTGGATTTTCATAGCAGATACGTCCCTATGNTGTTTGCTTATG TGAGCCAAGAGGTCATTAAAATGCTATTCACGAACAGAAAGACTTCTAATGGAAGCTGCT GTNCTAACTCAGCCTCTGCTAGAATGAATATGCTATCACAAAATCTTCAACAAGGTATAT CTTAGGATGCTAGCAGATAGCAAACTTCACTTACCCTATNNCTATGATAGCATGAAAGCA ACTAGAAAAATGCGTGAAAAAGGCAGGGTTAAAATNCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_016131 |
| Insert Size | 3570 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016131.2, NP_057215.2 |
| RefSeq Size | 3521 bp |
| RefSeq ORF | 603 bp |
| Locus ID | 10890 |
| UniProt ID | P61026 |
| Domains | ras, RAN, RAS, RHO, RAB |
| Protein Families | Druggable Genome |
| Gene Summary | RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10
,Wauters, F;Cornelissen, T;Imberechts, D;Martin, S;Koentjoro, B;Sue, C;Vangheluwe, P;Vandenberghe, W;,
Autophagy
,PubMed ID 30945962
[RAB10]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201464 | RAB10 (Myc-DDK-tagged)-Human RAB10, member RAS oncogene family (RAB10) |
CNY 3,600.00 |
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| RC201464L1 | Lenti ORF clone of Human RAB10, member RAS oncogene family (RAB10), Myc-DDK-tagged |
CNY 6,000.00 |
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| RC201464L2 | Lenti ORF clone of Human RAB10, member RAS oncogene family (RAB10), mGFP tagged |
CNY 5,890.00 |
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| RC201464L3 | Lenti ORF clone of Human RAB10, member RAS oncogene family (RAB10), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201464L4 | Lenti ORF clone of Human RAB10, member RAS oncogene family (RAB10), mGFP tagged |
CNY 5,890.00 |
|
| RG201464 | RAB10 (tGFP-tagged) - Human RAB10, member RAS oncogene family (RAB10) |
CNY 5,200.00 |
|
| SC322239 | RAB10 (untagged)-Human RAB10, member RAS oncogene family (RAB10) |
CNY 3,600.00 |
