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NYREN18 (NUB1) (NM_016118) Human Untagged Clone
CAT＃: SC114463
NUB1 (untagged)-Human negative regulator of ubiquitin-like proteins 1 (NUB1)
CNY 4,480.00
CNY 9,690.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BS4; NUB1L; NYREN18 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_016118, the custom clone sequence may differ by one or more nucleotides
ATGAAAACAAACGGCGGCCGCTGCCGCATCCGGGCACTCTGCTGGTCGCGGCGGGAGTGGCGTGGCGCAG GGATGGCACAAAAGAAATATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGACAGGATTCAACTTTG GAAACCTCCATATACAGATGAAAATAAAAAAGTTGGTTTGGCATTAAAGGACCTTGCTAAGCAGTACTCT GACAGACTAGAATGCTGTGAAAATGAAGTAGAAAAGGTAATAGAAGAAATACGTTGCAAGGCAATTGAGC GTGGAACAGGAAATGACAATTATAGAACAACGGGAATTGCTACAATCGAGGTGTTTTTACCACCAAGACT AAAAAAAGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTGAGGTCCAAAATA GCTGAAACCTTTGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCAACTACAACTAGGGA AAACCCTTGAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGTGCTTGAACTAAAACAATCTGAAGA GGACGCGAGGAAAAACTTCCAGTTAGAGGAAGAGGAGCAAAATGAGGCCAAACTCAAAGAAAAACAAATT CAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAGAGAGCAGCAGAGACAGTGGTGGATCCAGAAATGA CACCGTACTTAGACATAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCAGAAAGAAAAGCCCT TATGTTAGCTATGGGATATCATGAGAAGGGCAGAGCTTTCCTGAAAAGAAAAGAATATGGAATAGCCTTG CCATGTCTGTTGGACGCTGACAAATATTTCTGTGAGTGTTGCAGAGAGCTGCTGGACACAGTGGATAACT ACGCCGTCCTCCAGCTGGATATAGTGTGGTGTTACTTCCGCCTGGAACAGCTGGAATGCCTTGATGATGC AGAAAAAAAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTACGGAGAAAATCATCAGAGACTGGTC CACATAAAAGGAAATTGTGGGAAAGAGAAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATCCGAA ACTATCACAGTGGAAATGATGTAGAGGCTTATGAGTATCTTAACAAGGCACGTCAGCTCTTTAAAGAGCT ATATATTGATCCATCAAAAGTGGACAATTTGTTGCAGTTGGGGTTTACTGCCCAGGAAGCCCGGCTTGGC CTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCCACTCATATTACCAACCGCAGAGAGGAACTGGCCC AAATAAGGAAGGAGGAAAAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTTCTGAAAGGGATGGG CTACTCCACGCACGCGGCCCAGCAGATTCTGCTCAGCAATCCTCAGATGTGGTGGTTAAATGATTCCAAT CCTGAAACCGACAACCGTCAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTGGTGTACATGGGTTTTG ATGCACTCGTGGCCGAAGCTGCGCTGAGAGTGTTCAGAGGCAACGTCCAGCTGGCCGCCCAGACCCTTGC TCACAACGGAGGAAGCCTGCCTCCCGAGCTGCCGCTGTCGCCAGAAGACTCTTTGTCCCCGCCAGCCACG TCCCCTTCTGACTCCGCAGGAACCTCTAGTGCCTCAACAGACGAAGACATGGAGACAGAGGCCGTCAATG AGATACTGGAAGACATTCCAGAGCATGAGGAAGACTATCTTGACTCAACTCTGGAAGATGAAGAAATTAT TATTGCAGAGTACCTATCCTATGTAGAAAATAGGAAGTCAGCAACAAAGAAAAACTAA >OriGene 5' read for NM_016118 unedited
TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTTGGCACGAGGCTGGTCGCGGCGGG AGTGGCGTGGCGCAGGGATGGCACAAAAGAAATTCTTCAAGCAAAATTGACCCAGTTTTT AAGGGAAGACAGGATTCAACTTTGGAAACCTCCATATACAGATGAAAATAAAAAAGTTGG TTTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGACTAGAATGCTGTGAAAATGA AGTAGAAAAGGTAATAGAAGAAATACGTTGCAAGGCAATTGAGCGTGGAACAGGAAATGA CAATTATAGAACAACGGGAATTGCTACAATCGAGGTGTTTTTACCACCAAGACTAAAAAA AGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTGAGGTCCAA AATAGCTGAAACCTTTGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCA ACTACAACTAGGGAAAACCCTTGAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGT GCTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAACTTCCAGTTAGAGGAAGAGGA GCAAAATGAGGCCAAACTCANAGAANAACAAATTCAGAGGACCAAGAGAGGACTAGAAAT ACTGGCAAAGAGAGCAGCAGAGACAGTGGGTGGATCCAGAAATGACACCGTACTTAGACA TAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCCTCAGAAAGAAAGCCCTTATGTT AGCTATGGGATATCATGAGAAGGGCAGGNAGCTTCCTGAAAGAANAGATATGGNATAGCC TTGCCATGTCTGNTGGACGCTGACAATATTTCTGGTGAGTGTTGCAAAGAGCTGCTGGAC AA >OriGene 3' read for NM_016118 unedited
ACCGCGGCCGCATATTTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAAATATTTCCCACCT TTTATTTCCATCGGTATCATCCGTTTAAAAAGAATGACAAGAAGATTCCCATCAGTCCAA ACTGGACCACCCACACTTTGAAAAAGTTGGAGCATTTCAGCCGGCTCCGCATGATCCATC CTGTCTTCAGTCAGTGCCTTCTGGAAGGGAGGGAAAGTCTTGGATGCACCTGGCACTCAA TCCACTCGGCACCTGGCTGCTGCTGCGGTCCTGGGGCTGGAAGGAACTCCCACTGGGCAC ACATCTACAGAGGAGTGCGTGGCGCAGTGAGGACGGTTACTGCTGGAGCCGACACACAGC GAACTACATACTTTTAGAAAGAGCCTCTGTCACATGGCTAGAACAACAACAACAACAAAG AAAACCCACAAAAAACCTGGAGAAAATATATCTAAATCTCTGATAGGTCTCTTAGCTAGC AGTGAATTCAGTATGACAGCACAGAGTCTAAAAATATTAATTAAAAATAAATTGCTTTGG TTAGCATTTAAACCTTTCCCATTCAATAGAAGATTTCTGTAATGAGGAATGCTGAATATA TATAAAGCCTGACACTCAATCTTGAATTTCGGGGGCGTTTTTTACTGAACTAAGAGCATA AAACACTGGCGTCCCAGGCTGAAGGCATTTGCTGCCACCTGGTGTGGCCCCCAAAGCCAG CGCCTCATTGTTATGCCCCACAGGCCTTGGAAGGGAATACTTAAGGACCATTTGAGGGGC CGGGGAAGGGTGGGCCAGGAAACCATGGTGCACCCTGGCAGAATAGGCCCGCGGGAAATA AGAACGCCAGGCCATGTGTTCCCGAGGCCCGCCCTCCGTGCCATGGACCCCCCTGGAGAG AAAGCGGCGGGACACCCTTTCCAGAACCTGCCTCGGCACCTN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_016118 |
| Insert Size | 3370 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_016118.3, NP_057202.2 |
| RefSeq Size | 3112 bp |
| RefSeq ORF | 1806 bp |
| Locus ID | 51667 |
| UniProt ID | Q9Y5A7 |
| Domains | UBA |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in an isoform (2, also known as NUB1) that is shorter than isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208098 | NUB1 (Myc-DDK-tagged)-Human negative regulator of ubiquitin-like proteins 1 (NUB1) |
CNY 4,472.00 |
|
| RC208098L1 | Lenti ORF clone of Human negative regulator of ubiquitin-like proteins 1 (NUB1), Myc-DDK-tagged |
CNY 6,872.00 |
|
| RC208098L2 | Lenti ORF clone of Human negative regulator of ubiquitin-like proteins 1 (NUB1), mGFP tagged |
CNY 6,460.00 |
|
| RC208098L3 | Lenti ORF clone of Human negative regulator of ubiquitin-like proteins 1 (NUB1), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC208098L4 | Lenti ORF clone of Human negative regulator of ubiquitin-like proteins 1 (NUB1), mGFP tagged |
CNY 6,460.00 |
|
| RG208098 | NUB1 (tGFP-tagged) - Human negative regulator of ubiquitin-like proteins 1 (NUB1) |
CNY 6,072.00 |
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