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Apolipoprotein H (APOH) (NM_000042) Human Untagged Clone
CAT＃: SC113997
APOH (untagged)-Human apolipoprotein H (beta-2-glycoprotein I) (APOH)
CNY 3,656.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | B2G1; B2GP1; BG |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC113997 sequence for NM_000042 edited (data generated by NextGen Sequencing)
ATGATTTCTCCAGTGCTCATCTTGTTCTCGAGTTTTCTCTGCCATGTTGCTATTGCAGGA CGGACCTGTCCCAAGCCAGATGATTTACCATTTTCCACAGTGGTCCCGTTAAAAACATTC TATGAGCCAGGAGAAGAGATTACGTATTCCTGCAAGCCGGGCTATGTGTCCCGAGGAGGG ATGAGAAAGTTTATCTGCCCTCTCACAGGACTGTGGCCCATCAACACTCTGAAATGTACA CCCAGAGTATGTCCTTTTGCTGGAATCTTAGAAAATGGAGCCGTACGCTATACGACTTTT GAATATCCCAACACGATCAGTTTTTCTTGTAACACTGGGTTTTATCTGAATGGCGCTGAT TCTGCCAAGTGCACTGAGGAAGGAAAATGGAGCCCGGAGCTTCCTGTCTGTGCTCCCATC ATCTGCCCTCCACCATCCATACCTACGTTTGCAACACTTCGTGTTTATAAGCCATCAGCT GGAAACAATTCCCTCTATCGGGACACAGCAGTTTTTGAATGTTTGCCACAACATGCGATG TTTGGAAATGATACAATTACCTGCACGACACATGGAAATTGGACTAAATTACCAGAATGC AGGGAAGTAAAATGCCCATTCCCATCAAGACCAGACAATGGATTTGTGAACTATCCTGCA AAACCAACACTTTATTACAAGGATAAAGCCACATTTGGCTGCCATGATGGATATTCTCTG GATGGCCCGGAAGAAATAGAATGTACCAAACTGGGAAACTGGTCTGCCATGCCAAGTTGT AAAGCATCTTGTAAATTACCTGTGAAAAAAGCCACTGTGGTGTACCAAGGAGAGAGAGTA AAGATTCAGGAAAAATTTAAGAATGGAATGCTACATGGTGATAAAGTTTCTTTCTTCTGC AAAAATAAGGAAAAGAAGTGTAGCTATACAGAGGATGCTCAGTGTATAGATGGCACTATC GAAGTCCCCAAATGCTTCAAGGAACACAGTTCTCTGGCTTTTTGGAAAACTGATGCATCC GATGTAAAGCCATGCTAA Clone variation with respect to NM_000042.2 796 g=>t >OriGene 5' read for NM_000042 unedited
CATTTATGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCTCATCCACAAT GATTTCTCCAGTGCTCATCTTGTTCTCGAGTTTTCTCTGCCATGTTGCTATTGCAGGACG GACCTGTCCCAAGCCAGATGATTTACCATTTTCCACAGTGGTCCCGTTAAAAACATTCTA TGAGCCAGGAGAAGAGATTACGTATTCCTGCAAGCCGGGCTATGTGTCCCGAGGAGGGAT GAGAAAGTTTATCTGCCCTCTCACAGGACTGTGGCCCATCAACACTCTGAAATGTACACC CAGAGTATGTCCTTTTGCTGGAATCTTAGAAAATGGAGCCGTACGCTATACGACTTTTGA ATATCCCAACACGATCAGTTTTTCTTGTAACACTGGGTTTTATCTGAATGGCGCTGATTC TGCCAAGTGCACTGAGGAAGGAAAATGGAGCCCGGAGCTTCCTGTCTGTGCTCCCATCAT CTGCCCTCCACCATCCATACCTACGTTTGCAACACTTCGTGTTTATAAGCCATCAGCTGG AAACAATTCCCTCTATCGGGACACAGCAGTTTTTGAATGTTTGCCACAACATGCGATGTT TGGAAATGATACAATTACCTGCACGACACATGGAAATTGGACTAAATTACCAGAATGCAG GGAAGTAAAATGCCCATTCCCATCAAGACCAGACAATGGATTTGTGAACTATCCTGCANA ACCAACACTTTATTACAAGGATAAAGCCACATTTGGCTGCCATGATGGATATTCTCTGGA TGGCCCGGNNAGAATAGAATGTACCAAACTGGGAAACTGGTCTGCCATGCCAAGTNTGTA AGCATCTTTGTAATTACCTGTGAAAAAGCCACTGTGGTGTACCAAGGNAGAGAGAGTAAG ATTCAGGAAAATTTNAGATGGNATGCTACATGTNGATAAGTTNCTTTCTTCTGCAAATAN GGNAAAGNAGTGTAGCTTACAGAGCTGC >OriGene 3' read for NM_000042 unedited
NTTTTACTCTGNACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGCGG CAATAAATTCAGTAGCTTTATTTTTAAATTTCAATTAGGTTCCTTGGATGAACAAGAAAC AAGTGTGACATTTTATGTGGAATCTGAAAACCACCTTAGCATGGCTTTACATCGGATGCA TCAGTTTTCCAAAAAGCCAGAGAACTGTGTTCCTTGAAGCATTTGGGGACTTCGATAGTG CCATCTATACACTGAGCATCCTCTGTATAGCTACACTTCTTTTCCTTATTTTTGCAGAAG AAAGAAACTTTATCACCATGTAGCATTCCATTCTTAAATTTTTCCTGAATCTTTACTCTC TCTCCTTGGTACACCACAGTGGCTTTTTTCACAGGTAATTTACAAGATGCTTTACAACTT GGCATGGCAGACCAGTTTCCCAGTTTGGTACATTCTATTTCTTCCGGGCCATCCAGAGAA TATCCATCATGGCAGCCAAATGTGGCTTTATCCTTGTAATAAAGTGTTGGTTTTGCAGGA TAGTTCACAAATCCATTGTCTGGTCTTGATGGGAATGGGCATTTTACTTCCCTGCATTCT GGTAATTTAGTCCAATTTCCATGTGTCGTGCAGGTAATTGTATCATTTCCAAACATCGCA TGTTGTGGCAAACATTCAAAAACTGCTGTGTCCCGATAGAGGGAATTGTTTCCAGCTGAT GGCTTATAAACACGAAGTGTTGCAAACGTANGTATGGATGGTGGAGGGCANATGATGGGA GCACAGACAGGAAAGCTCCGGCTNCATTTTCCTTTCTCAGTGCACTTGGCAGAATCAGCG CCATTCAGATAAACCCAGTGTTACAAGAAAACTGATCGTGTGGGNAATTCAAAAGTCGTA TAGCGTACGGCTCCATTTTCTAAGATCCAGCAAAGGACTACTCTC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000042 |
| Insert Size | 1170 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000042.1, NP_000033.1 |
| RefSeq Size | 1182 bp |
| RefSeq ORF | 1038 bp |
| Locus ID | 350 |
| UniProt ID | P02749 |
| Domains | CCP |
| Protein Families | Druggable Genome, Secreted Protein |
| Gene Summary | Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.[provided by RefSeq, Dec 2019] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205017 | APOH (Myc-DDK-tagged)-Human apolipoprotein H (beta-2-glycoprotein I) (APOH) |
CNY 3,656.00 |
|
| RC205017L1 | Lenti ORF clone of Human apolipoprotein H (beta-2-glycoprotein I) (APOH), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC205017L2 | Lenti ORF clone of Human apolipoprotein H (beta-2-glycoprotein I) (APOH), mGFP tagged |
CNY 5,890.00 |
|
| RC205017L3 | Lenti ORF clone of Human apolipoprotein H (beta-2-glycoprotein I) (APOH), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC205017L4 | Lenti ORF clone of Human apolipoprotein H (beta-2-glycoprotein I) (APOH), mGFP tagged |
CNY 6,056.00 |
|
| RG205017 | APOH (tGFP-tagged) - Human apolipoprotein H (beta-2-glycoprotein I) (APOH) |
CNY 5,256.00 |
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