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MBNL1 (NM_021038) Human Untagged Clone
CAT＃: SC113012
MBNL1 (untagged)-Human muscleblind-like (Drosophila) (MBNL1), transcript variant 1
CNY 3,656.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EXP; MBNL |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_021038, the custom clone sequence may differ by one or more nucleotides
ATGGCTGTTAGTGTCACACCAATTCGGGACACAAAATGGCTAACACTGGAAGTATGTAGAGAGTTCCAGA GGGGGACTTGCTCACGGCCAGACACGGAATGTAAATTTGCACATCCTTCGAAAAGCTGCCAAGTTGAAAA TGGACGAGTAATCGCCTGCTTTGATTCATTGAAAGGCCGTTGCTCCAGGGAGAACTGCAAATATCTTCAT CCACCCCCACATTTAAAAACGCAGTTGGAGATAAATGGACGCAATAACTTGATTCAGCAGAAGAACATGG CCATGTTGGCCCAGCAAATGCAACTAGCCAATGCCATGATGCCTGGTGCCCCATTACAACCCGTGCCAAT GTTTTCAGTTGCACCAAGCTTAGCCACCAATGCATCAGCAGCCGCCTTTAATCCCTATCTGGGACCTGTT TCTCCAAGCCTGGTCCCGGCAGAGATCTTGCCGACTGCACCAATGTTGGTTACAGGGAATCCGGGTGTCC CTGTACCTGCAGCTGCTGCAGCTGCTGCACAGAAATTAATGCGAACAGACAGACTTGAGGTATGTCGAGA GTACCAACGTGGCAATTGCAACCGAGGAGAAAATGATTGTCGGTTTGCTCATCCTGCTGACAGCACAATG ATTGACACCAATGACAACACAGTCACTGTGTGTATGGATTACATCAAAGGGAGATGCTCTCGGGAAAAGT GCAAATACTTTCATCCCCCTGCACATTTGCAAGCCAAGATCAAGGCTGCCCAATACCAGGTCAACCAGGC TGCAGCTGCACAGGCTGCAGCCACCGCAGCTGCCATGGGAATTCCTCAAGCTGTACTTCCCCCATTACCA AAGAGGCCTGCTCTTGAAAAAACCAACGGTGCCACCGCAGTCTTTAACACTGGTATTTTCCAATACCAAC AGGCTCTAGCCAACATGCAGTTACAACAGCATACAGCATTTCTCCCACCAGGCTCAATATTGTGCATGAC ACCCGCTACAAGTGTTGTTCCCATGGTGCACGGTGCTACGCCAGCCACTGTGTCCGCAGCAACAACATCT GCCACAAGTGTTCCCTTCGCTGCAACAGCCACAGCCAACCAGATACCCATAATATCTGCCGAACATCTGA CTAGCCACAAGTATGTTACCCAGATGTAG >OriGene 5' read for NM_021038 unedited
NGGTCAAATTGATACACTATTAGGCGCCGGATTCGCCGATCTGCCGGAAATAAGAGGAAA AAAAAATCATTTTCTCGATTTTGCTCTAAACTGCTACTTCTGTCTATGCCAAACTAATCA ATACCGATTGCACCACCAAACTCCATTGCAAATTCAGCTGTGAGGAGATTCCCTTTCAGA CAACTTTGCTGAAAGCAGCTTGGAAATTCGGTGTCGAAGGGTCTGCCACGTTTTCATGCT TGCATTTTGGGCTCCAAATTGGCACTGGGAAGGGGTTACTGAGAGCACAAGGCTGATACC AGGCCCTACTTTTAAACGTTCATCTACTTACAATCCTAGTATTTCTCTAAAAACCAAAAC CTCTTTGAATTAACAGTTTCATGCTGTGAATTTCTAGTGGGAGATCTTTTCCTTGATATT GACGACACAATTTTCCATGTACTTTTAAAGCAGGGAGTGGGGAAAAGTATTTTGAGGGGA CATTCTCATCATCAGTTCAGCTTTTTTTTTTTGGTTGTTGCTCTTTTTTGGGGGGGTTGG GTTTGTTGGTTTCACTGAAACATTTAACTACCTGTAAAATCTAAACATGGCTGTTAGTGT CACACCAATTCGGGACACAAAATGGCTAACACTGGAAGTATGTAGAGAGTTCCAGAGGGG GACTTGCTCACGGCCAGACACGGAATGTAAATTTGCACATCCTTCGAAAAGCTGCCAAGT TGAAAATGGACGAGTAATCGCCTGCTTTGATTCATTGAAAGGCCGTTGCTCCAGGGAGAA CTGCAAATATCTTCATCCACCCCCACATTTAANAACGCAGTTGGAGATAAATGGACGCCA TAACTTGATTCAGCAGAAGACATGGCC >OriGene 3' read for NM_021038 unedited
GGGGGGGTTGAAATTTTAAACATGCATAGTTTTGAAAAAGTAAGGAATATCTGATCCATG ATTTCACCTTAATGGTAAAAGTACCTGCTATTTTTGGTAATGATCTTCAGGCAAATTTGG CCCCATGGAGTTTTTGTCAGTCATGAGGGTTTGAAAGGATGGCGTATCTTTCCAGCTGAA AAAAATCCTGGCAAACTACAAGCTGTCCACAAAAAAGCAAAGCAACATGTTTGAAGGGGT ATGGAGTGCTAACTCTGTGCCACTTTTGCAAGCAATTTTGCTCAGTCTGTCATTGTATTA CCCTTAACAAAACTCCTTGTAATTATAGACGTTTTTATTCAAAATAAAATCTTACTATTA TACAGGTTTCTCTCTTTTGACTATATACAGAAGTGCAAAAAGTCAACCTTCTCCCTAAAC GTTCCAACATGCTAAATTGCAGCATAATCAACCCTCAAGAGTTTGCACACACGCTATAAT TTTCATTACGTAAACTTTGAGTATTTGGATTATCAACAAAAAGTCCCTTGTTCTATTTAT TGATTATGCAGCTTATTTATAACAAGGCCTGATACTCAGGGATTTCAAAAATATTAAACA ATATTTTAACATTTGAAATGGATACAGTAAAAAATAAATTTTATTCTAATATCTAGGATC TAGATCTTCTTATAATAACTAATTACAAACAAAATAAATCATCAAAATATTACTCAAATT GTCTGCCAGGAATTGGNNGCGATAGCAACCAACCTTAACTTCTTACTTNAGCAATGATTA ATATATTNTATAAAGATATCCATATAAAAGAACCTTTTGTTCCTTTTAATGAAACCTACA CAAGAACTAACAGGGACTGGCATNCTTTAACCTGAAATATAAAATCAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021038 |
| Insert Size | 4570 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021038.3, NP_066368.2 |
| RefSeq Size | 6404 bp |
| RefSeq ORF | 1149 bp |
| Locus ID | 4154 |
| UniProt ID | Q9NR56 |
| Domains | zf-CCCH |
| Gene Summary | This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015] Transcript Variant: This variant (1) represents the longest transcript and it encodes isoform a. Other names for this isoform are EXP41 and MBNL1subscript41. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Muscleblind‑like 1 destabilizes Snail mRNA and suppresses the metastasis of colorectal cancer cells via the Snail/E‑cadherin axis
,Tang, L;Zhao, P;Kong, D;,
Int. J. Oncol.
,PubMed ID 30664186
[MBNL1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208112 | MBNL1 (Myc-DDK-tagged)-Human muscleblind-like (Drosophila) (MBNL1), transcript variant 1 |
CNY 3,656.00 |
|
| RC208112L1 | Lenti ORF clone of Human muscleblind-like (Drosophila) (MBNL1), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC208112L2 | Lenti ORF clone of Human muscleblind-like (Drosophila) (MBNL1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC208112L3 | Lenti ORF clone of Human muscleblind-like (Drosophila) (MBNL1), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC208112L4 | Lenti ORF clone of Human muscleblind-like (Drosophila) (MBNL1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG208112 | MBNL1 (tGFP-tagged) - Human muscleblind-like (Drosophila) (MBNL1), transcript variant 1 |
CNY 5,256.00 |
