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TMEM35 (TMEM35A) (NM_021637) Human Untagged Clone
CAT＃: SC112910
TMEM35 (untagged)-Human transmembrane protein 35 (TMEM35)
CNY 2,400.00
CNY 2,950.00
| Cited in 8 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NACHO; TMEM35; TUF-1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112910 sequence for NM_021637 edited (data generated by NextGen Sequencing)
ATGGCATCCCCCAGAACCGTAACTATTGTGGCCCTCTCAGTGGCCCTGGGACTCTTCTTT GTTTTCATGGGGACTATCAAGCTGACCCCCAGGCTCAGCAAGGATGCCTACAGTGAGATG AAACGTGCTTACAAGAGCTATGTTCGAGCCCTCCCTCTGCTGAAGAAAATGGGGATCAAT TCCATTCTCCTCCGAAAAAGCATTGGTGCCCTTGAAGTGGCCTGTGGCATCGTCATGACC CTTGTGCCTGGGCGTCCCAAAGATGTGGCCAACTTCTTCCTACTGTTGCTGGTGTTGGCT GTGCTCTTCTTCCACCAGCTGGTCGGTGATCCTCTCAAACGCTACGCCCATGCTCTGGTG TTTGGAATCCTGCTCACTTGCCGCCTGCTGATTGCTCGCAAGCCCGAAGACCGGTCTTCT GAGAAGAAGCCTTTGCCAGGGAATGCTGAGGAGCAACCCTCCTTATATGAGAAGGCCCCT CAGGGCAAAGTGAAGGTGTCATAG Clone variation with respect to NM_021637.2 >OriGene 5' read for NM_021637 unedited
GTAAAGGACGTACCGTTGTATAACGCCTCCTAATAGGGCGGCCCGCGACTCTTCGGCAAC GAGTCCTCGTGCCGAATTCGGCACGAGGCCTTTGTCATTCTAGCTGCCTGCTGCCTCCGC AGCGTCCCCCCAGCTCTCCCTGTGCTAACTGCCTGCACCTTGGACAGAGCGGGTGCGCAA ATCAGAAGGATTAGTTGGGACCTGCCTTGGCGACCCCATGGCATCCCCCAGAACCGTAAC TATTGTGGCCCTCTCAGTGGCCCTGGGACTCTTCTTTGTTTTCATGGGGACTATCAAGCT GACCCCCAGGCTCAGCAAGGATGCCTACAGTGAGATGAAACGTGCTTACAAGAGCTATGT TCGAGCCCTCCCTCTGCTGAAGAAAATGGGGATCAATTCCATTCTCCTCCGAAAAAGCAT TGGTGCCCTTGAAGTGGCCTGTGGCATCGTCATGACCCTTGTGCCTGGGCGTCCCAAAGA TGTGGCCAACTTCTTCCTACTGTTGCTGGTGTTGGCTGTGCTCTTCTTCCACCAGCTGGT CGGTGATCCTCTCAAACGCTACGCCCATGCTCTGGTGTTTGGAATCCTGCTCACTTGCCG CCTGCTGATTGCTCGCAAGCCCGAAGACCGGTCTTCTGAGAAGAAGCCTTTGCCAGGGAA TGCTGAGGAGCAACCCTCCTTATATGAGAAGGCCCCTCAGGGCAAAGTGAAGGTGTCATA GAAAAGTGGAAGTGCAAAGAGTGGACCTTCCAGGCAGTTGCGTCCATGACACCAGGAAGA TGTCAGTGTGTGTTTTTCATTTGATTTATTTATCTTGGGGAAAGTGAAAAATGTAATCTG CAAGTTAATGACCCTATTGGCTTGTGTACATCTATATGCTAAAATGACTTCCCCACATTG ACATTTGTGCGCCACCTTTTATT >OriGene 3' read for NM_021637 unedited
TATGGACGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCA AATTTCAAAAAGTTTTATTTTGAAAGAATGAGAGAAATAAAACAGAGAGGTTTCAATTAC CAAAAACAATTACACTGAAAAAAACACAATAATAAGTACTTTTCCCACACAACCCCCCCC ATTTCCCCATCCCTGGCACAATAATATTAAAACCACCAAAGCACACCTAACAAGGAAAAA CAACAGTACGTAATGAAAAAAGCAAATGTCCATACTGCTCAGTCCAACTAACCCTTATGA AATGTCCTTCCCCCAGCTAAACCCTACCCACTGGAATGATAAAAAAATGTAAAGACAACC CTAGGGGAAACTTGGAACTCTGCTTATACTAGCAAAGCTCAGTGAAAAATCAGTAAAAGT AGTGAATCTGTTTGGCAGTGAAACACTGGATATAGCTTCTTTTTCAAATTTTGGATGATT GCAAAAAACAGGTAAAGTTTGAGGCTCACAGACTTCTAACAGGACTGATCCCTGTTCCCT CAACCGTAACAGTGGAGCAGCTGCCAAATCCTGGTTGGCTGCTGAAAATAGTGGAAGTGA GGCAACTTTGGGCTTAAGACAATCTGAAAAAGATGTCTGGAAACAAGTTTACTGCTTCAG TTTCAAACTGTGAGTAAAGGGTTTTAATAGGTGGGGCTTGGACAAAGGCAGGTTGAAACT TCCATATTATCACTTGAAGAATTAAACTATCAATTTGACTGCATGCATCCCCTTGTTTTA AATAAATTCAATATGGGACTATTTAAAAATGTAAACNAACTGTTGGNACTAGAGCCTAAT TAAATTCATATANTAACTCANTGTCCGAAAATGAATGTTTTTTTTTTTTCTCCTAAGTAA TAAAGTTTAGNTTGTAGTATCTGGTGGAAAGATT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021637 |
| Insert Size | 504 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021637.1, NP_067650.1 |
| RefSeq Size | 2039 bp |
| RefSeq ORF | 504 bp |
| Locus ID | 59353 |
| UniProt ID | Q53FP2 |
| Protein Families | Transmembrane |
| Gene Summary | A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth.[UniProtKB/Swiss-Prot Function] |
Citations (8)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
An experimental test of the nicotinic hypothesis of COVID-19
,null,
Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 36279466
[TMEM35A]
|
|
Aβ1-16 controls synaptic vesicle pools at excitatory synapses via cholinergic modulation of synapsin phosphorylation
,Anni, D;Weiss, EM;Guhathakurta, D;Akdas, YE;Klueva, J;Zeitler, S;Andres-Alonso, M;Huth, T;Fejtova, A;,
Cellular and molecular life sciences : CMLS
,PubMed ID 33864480
[TMEM35A]
|
|
NACHO Engages N-Glycosylation ER Chaperone Pathways for α7 Nicotinic Receptor Assembly
,Kweon, HJ;Gu, S;Witham, E;Dhara, M;Yu, H;Mandon, ED;Jawhari, A;Bredt, DS;,
Cell Rep
,PubMed ID 32783947
[TMEM35A]
|
|
Isomerization of Asp7 in Beta-Amyloid Enhances Inhibition of the α7 Nicotinic Receptor and Promotes Neurotoxicity
,Barykin, EP;Garifulina, AI;Kruykova, EV;Spirova, EN;Anashkina, AA;Adzhubei, AA;Shelukhina, IV;Kasheverov, IE;Mitkevich, VA;Kozin, SA;Hollmann, M;Tsetlin, VI;Makarov, AA;,
Cells
,PubMed ID 31349637
[TMEM35A]
|
|
New rigid nicotine analogs, carrying a norbornane moiety, are potent agonists of α7 and α3* nicotinic receptors
,Manetti, D;Garifulina, A;Bartolucci, G;Bazzicalupi, C;Bellucci, C;Chiaramonte, N;Dei, S;Di Cesare Mannelli, L;Ghelardini, C;Gratteri, P;Spirova, E;Shelukhina, I;Teodori, E;Varani, K;Tsetlin, V;Romanelli, MN;,
J. Med. Chem.
,PubMed ID 30681854
[TMEM35A]
|
|
Curare alkaloids from Matis Dart Poison: Comparison with d-tubocurarine in interactions with nicotinic, 5-HT3 serotonin and GABAA receptors
,Spirova, EN;Ivanov, IA;Kasheverov, IE;Kudryavtsev, DS;Shelukhina, IV;Garifulina, AI;Son, LV;Lummis, SCR;Malca-Garcia, GR;Bussmann, RW;Hennig, L;Giannis, A;Tsetlin, VI;,
PLoS ONE
,PubMed ID 30608952
[TMEM35A]
|
|
Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors
,Durek, T;Shelukhina, IV;Tae, HS;Thongyoo, P;Spirova, EN;Kudryavtsev, DS;Kasheverov, IE;Faure, G;Corringer, PJ;Craik, DJ;Adams, DJ;Tsetlin, VI;,
Sci Rep
,PubMed ID 29192197
[TMEM35A]
|
|
Calcium imaging with genetically encoded sensor Case12: Facile analysis of α7/α9 nAChR mutants
,Shelukhina, I;Spirova, E;Kudryavtsev, D;Ojomoko, L;,
PloS one
,PubMed ID 28797116
[TMEM35A]
|
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Resources
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| RC209790 | TMEM35 (Myc-DDK-tagged)-Human transmembrane protein 35 (TMEM35) |
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| RC209790L4 | Lenti ORF clone of Human transmembrane protein 35 (TMEM35), mGFP tagged |
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| RG209790 | TMEM35 (tGFP-tagged) - Human transmembrane protein 35 (TMEM35) |
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