SAV1 (NM_021818) Human Untagged Clone
CAT#: SC112869
SAV1 (untagged)-Human salvador homolog 1 (Drosophila) (SAV1)
CNY 3,656.00
Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | SAV; WW45; WWP4 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_021818 edited
GAATTCGGCACGAGGGCCGGCGCCCGGCGCGGAGCCCTAGGGAGGCAGTTCAGCGCGGCC TCGGGCCTCGTCGAGAAGGATGCTGTCCCGAAAGAAAACCAAAAACGAAGTGTCCAAGCC GGCCGAGGTGCAGGGGAAGTACGTGAAGAAGGAGACGTCGCCTCTGCTTCGGAATCTTAT GCCTTCATTCATCCGGCATGGTCCAACAATTCCAAGACGAACTGATATCTGTCTTCCAGA TTCAAGCCCTAATGCCTTTTCAACTTCTGGAGATGTAGTTTCAAGAAACCAGAGTTTCCT TAGAACTCCAATTCAAAGAACACCTCATGAAATAATGAGAAGAGAAAGCAACAGATTATC TGCACCTTCTTATCTTGCCAGAAGTCTAGCAGATGTCCCTAGAGAGTATGGTTCTTCTCA GTCATTTGTAACGGAAGTTAGTTTTGCTGTTGAAAATGGAGACTCTGGTTCCCGATATTA TTATTCAGACAATTTTTTTGATGGTCAGAGAAAGCGGCCACTTGGAGATCGTGCACATGA AGACTACAGATATTATGAATACAACCATGATCTCTTCCAAAGAATGCCACAGAATCAGGG GAGGCATGCTTCAGGTATTGGGAGAGTTGCTGCTACATCTTTAGGAAATTTGACTAACCA TGGTTCTGAAGATTTACCCCTTCCTCCTGGCTGGTCTGTGGACTGGACAATGAGAGGGAG AAAATATTATATAGATCATAACACAAATACAACTCACTGGAGCCATCCTCTTGAGCGAGA AGGACTTCCTCCTGGATGGGAACGAGTTGAGTCATCCGAATTTGGAACCTATTATGTAGA TCACACAAATAAGAAGGCCCAATACAGGCATCCCTGTGCTCCTAGTGTACCTCGGTATGA TCAACCACCTCCTGTCACATACCAGCCACAGCAAACTGAAAGAAATCAGTCCCTTCTGGT ACCTGCAAATCCATATCATACTGCAGAAATTCCTGACTGGCTTCAGGTTTACGCACGAGC CCCTGTGAAATATGACCACATTCTGAAGTGGGAACTCTTCCAGCTGGCTGACCTGGATAC ATACCAGGGAATGCTAAAGTTGCTCTTCATGAAAGAATTGGAGCAGATTGTTAAAATGTA TGAAGCATACAGACAAGCCCTTCTTACAGAGTTGGAAAACCGAAAGCAGAGACAGCAGTG GTATGCCCAACAACATGGAAAAAATTTTTGAGCTGATTTTTTAAAAATTTAAGTTTTGTA AGAGCTTTAAAATATTTTCACAGATAAAAAATTGCAAACAAGTACTCTGGTTAATAAATG CTGCTTCCTTTGTGGAAATTATAAAATTCTAACTTTACATGTATTTTGTTATTAGAAATT TTCTTTTATTGAATGAGAAAAATTAGTCTATCATTTTAAGAGCCAATATGGCAAACACTT TCAAATACTGTATATTAGGAAACTGTTTTGGTATTCTTGATGGAAAAAAACGCAGCGGAA ATGTCATTATGAACAGATGTTAAATAGGAAATTATTACTTGTTAACTTCTTACAGCAGTA GTACCTTCTTTAAAAAAAAAAAAGAATCTGCGGTATTTTTTTAAAAAAAAAGTTTACTGC TGTAGTGTGAAATATTGTCTGGAAAGGGATGGTTTAAATATTACCATGATGTAGTTGAAA TATAAAATAGGATTTGGAACCTTATTGTGATAAATATTTATATATGATGTATGTTTGTCT CCCCTCTCCAAAGTAAGGAACCCAGCTGGGCGTGGTGGCTCACTCCTGTAATCCCAGCAT TTTGGGAGGCCGAGGTGGGTGGACCGCTTGAGTCCACGAGTTTAAGACCAGCCTGGGCAA CATGGTGAAGCCCCATCTCTACAAAAAATACAAAAAAATTAGCCGGGTATGATGGTGTGT GCCTCTAGTCCCAGCTACTTGGGAGGCTGAGGTCAGAGGATGGCTTGAGCCCAAGAGGCA GAGGTTGCAGGGTCAAGATCGCACCACTTGCACTGCAGCCTGAGAGAGAGAGAGCCAGAC CTTGTCTCAAAAAAATAAAAAATAAAAAAATAAAAACAAAATAAGGAATCCTTTTAAAGC ATGTTGAGAAAGTATTTTTTGGTATGAATGGGTGACGGGCCTTTTAATCTTTCAGGAATA CATATAAGCAGGAATACTTAGCCTGTATTGGGAAGGTGCGTGAAACTCAAAGTTGCTAAC ATCATCTTCCTTATTTTCAGCCAGTGCTGTTACTGCATTTAGCATGGCTCTGACGAGGCA GTGGAGAGTTCCTGACAGCATAGCATACTGCCTTCTGACAGACTGGGTTAAGCTACCAAA AATGACAACCAGGGATTCAAAAAAAAAATTTTTGGTCATTAAATCGAATGTATATTATTA CTTTTTAATTTTCTAAGTATTTATCACAGGACTTTAACACCATATATTTCCCTCCCAGTT TTTCTCCCCTTTTGGTTTAATAGTTAAAACATTTTTCATAATTAGTGCTGTACATTTGAT TGCAAACAAATTGGTGATACTTCTAAACTATAACTATAAATCTCTAGAATTCTGTGAATT TCAACATTATTTGAAGTAGTTCTTCAGTTATATTTACATGTGTTGTAAATATGTAAATAT ACTTTTAGCTTAGGAAGTCTTCCAGAATACAAACTACTCCCAGTTAGATATCAGTGAGTT TGAATAACTGAAGAAATGTTGACAATGTTAAGTGTTTGATTTTATATAACAAGCTTATTA AATATATTTTTGTGGAAACTAAAAAAAAACAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_021818 unedited
ACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCCGGCGCCCGGCGCGGAGCCC TAGGGAGGCAGTTCAGCGCGGCCTCGGGCCTCGTCGAGAAGGATGCTGTCCCGAAAGAAA ACCAAAAACGAAGTGTCCAAGCCGGCCGAGGTGCAGGGGAAGTACGTGAAGAAGGAGACG TCGCCTCTGCTTCGGAATCTTATGCCTTCATTCATCCGGCATGGTCCAACAATTCCAAGA CGAACTGATCTCTGTCTTCCAGATTCAAGCCCTAATGCCTTTTCAACTTCTGGAGATGTA GTTTCAAGAAACCAGAGTTTCCTTAGAACTCCAATTCAAAGAACACCTCATGAAATAATG AGAAGAGAAAGCAACAGATTATCTGCACCTTCTTATCTTGCCAGAAGTCTAGCAGATGTC CCTAGAGAGTATGGTTCTTCTCAGTCATTTGTAACGGAAGTTAGTTTTGCTGTTGAAAAT GGAGACTCTGGTTCCCGATATTATTATTCAGACAATTTTTTTGATGGTCAGAGAAAGCGG CCACTTGGAGATCGTGCACATGAAGACTACAGATATTATGAATACAACCATGATCTCTTC CAAAGAATGCCACAGAATCAGGGGAGGCATGCTTCAGGTATTGGGAGAGTTGCTGCTACA TCTTTAGGAAATTTGACTAACCATGGGTCTGAAGATTTACCCCTTCCTCCTGGCTGGTCT GTGGACTGGACATGAGAGGGAGAAATATATATAGATCATACACANATACCACTCACTGGA GCCATCCTCTTGAGCGAAANGGACCTTCTNCTGGATGGGAACGAGNTGAGTCATTCGAAT TTGGACCTATATTGTAGATCACACAATAAGAGGNCCATACAGGCATCCCTGTGCTCTAGT GTACTCGGATGATCACCACCTCTGTACATACCAGCACAGAACTGAAGAAATAGTCCCTTT TGTACTGCAATCTATAACTGAG >OriGene 3' read for NM_021818 unedited
CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGTTTTTTTTAGTTTCCA CAAAAATATATTTAATAAGCTTGTTATATAAAATCAAACACTTAACATTGTCAACATTTC TTCAGTTATTCAAACTCACTGATATCTAACTGGGAGTAGTTTGTATTCTGGAAGACTTCC TAAGCTAAAAGTATATTTACATATTTACAACACATGTAAATATAACTGAAGAACTACTTC AAATAATGTTGAAATTCACAGAATTCTAGAGATTTATAGTTATAGTTTAGAAGTATCACC CATTTTGTTTGGCATCAAATGTTCAGCCCTAATTTTTGAAAAAGGTTTAACCTTTAAACC CAAGGGGGGAAAAAAATGGGGGGGGAAAATTTGGGGGGAAAAACCCCGGGAAAAACCTCC AAAAAAAAAAAAAGGGTTTTTCCCCCCCCCCGAGAAAAACCCAAAAATTTTTTTTTTAAA ACCCCCCGGGGGTTTTTTTGGGGACCCCCACCCCCCCCCAAAGAGAAGGGTTTTTTTGTT TGGAAAAACACCCCCTTCCCCAAAAAACCTTTTTTTTTAAACACCCCCCCTTTTTTAAAA AAAAAAAAAAANNTTTTTTTTTTTTNCCCCCCCCCCCCCCCCAACAAAAAATAATTTTTT TTTTTTTTTTGAAAAAAAAAAAGGGCCCCCCCCCCCCCCCCAAAAAAAAAANNGTGTTTN NNGGGAGGGGGGGGGGGGGGNNATTTNTCTTTTTTTTTTTTTTTAAAAAAAAAAAGGGCG CCCCCNCCCTTTCCCCCCGGCGGGGGGGGGGGGGGGGGACCCCCCCCCCCCA |
Restriction Sites | NotI-NotI |
ACCN | NM_021818 |
Insert Size | 2800 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_021818.2, NP_068590.1 |
RefSeq Size | 3031 bp |
RefSeq ORF | 1152 bp |
Locus ID | 60485 |
UniProt ID | Q9H4B6 |
Domains | WW |
Gene Summary | WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Actin-binding and Cell Proliferation Activities of Angiomotin Family Members are Regulated by Hippo Pathway-mediated Phosphorylation
,Chan, SW;Lim, CJ;Guo, F;Tan, I;Leung, T;Hong, W;,
J. Biol. Chem.
,PubMed ID 24225952
[SAV1]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204389 | SAV1 (Myc-DDK-tagged)-Human salvador homolog 1 (Drosophila) (SAV1) |
CNY 3,656.00 |
|
RC204389L3 | Lenti ORF clone of Human salvador homolog 1 (Drosophila) (SAV1), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC204389L4 | Lenti ORF clone of Human salvador homolog 1 (Drosophila) (SAV1), mGFP tagged |
CNY 5,890.00 |
|
RG204389 | SAV1 (tGFP-tagged) - Human salvador homolog 1 (Drosophila) (SAV1) |
CNY 5,256.00 |