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FOXM1 (NM_021953) Human Untagged Clone
CAT＃: SC112825
FOXM1 (untagged)-Human forkhead box M1 (FOXM1), transcript variant 2
CNY 5,600.00
| Cited in 6 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112825 sequence for NM_021953 edited (data generated by NextGen Sequencing)
ATGAAAACTAGCCCCCGTCGGCCACTGATTCTCAAAAGACGGAGGCTGCCCCTTCCTGTT CAAAATGCCCCAAGTGAAACATCAGAGGAGGAACCTAAGAGATCCCCTGCCCAACAGGAG TCTAATCAAGCAGAGGCCTCCAAGGAAGTGGCAGAGTCCAACTCTTGCAAGTTTCCAGCT GGGATCAAGATTATTAACCACCCCACCATGCCCAACACGCAAGTAGTGGCCATCCCCAAC AATGCTAATATTCACAGCATCATCACAGCACTGACTGCCAAGGGAAAAGAGAGTGGCAGT AGTGGGCCCAACAAATTCATCCTCATCAGCTGTGGGGGAGCCCCAACTCAGCCTCCAGGA CTCCGGCCTCAAACCCAAACCAGCTATGATGCCAAAAGGACAGAAGTGACCCTGGAGACC TTGGGACCAAAACCTGCAGCTAGGGATGTGAATCTTCCTAGACCACCTGGAGCCCTTTGC GAGCAGAAACGGGAGACCTGTGCAGATGGTGAGGCAGCAGGCTGCACTATCAACAATAGC CTATCCAACATCCAGTGGCTTCGAAAGATGAGTTCTGATGGACTGGGCTCCCGCAGCATC AAGCAAGAGATGGAGGAAAAGGAGAATTGTCACCTGGAGCAGCGACAGGTTAAGGTTGAG GAGCCTTCGAGACCATCAGCGTCCTGGCAGAACTCTGTGTCTGAGCGGCCACCCTACTCT TACATGGCCATGATACAATTCGCCATCAACAGCACTGAGAGGAAGCGCATGACTTTGAAA GACATCTATACGTGGATTGAGGACCACTTTCCCTACTTTAAGCACATTGCCAAGCCAGGC TGGAAGAACTCCATCCGCCACAACCTTTCCCTGCACGACATGTTTGTCCGGGAGACGTCT GCCAATGGCAAGGTCTCCTTCTGGACCATTCACCCCAGTGCCAACCGCTACTTGACATTG GACCAGGTGTTTAAGCCACTGGACCCAGGGTCTCCACAATTGCCCGAGCACTTGGAATCA CAGCAGAAACGACCGAATCCAGAGCTCCGCCGGAACATGACCATCAAAACCGAACTCCCC CTGGGCGCACGGCGGAAGATGAAGCCACTGCTACCACGGGTCAGCTCATACCTGGTACCT ATCCAGTTCCCGGTGAACCAGTCACTGGTGTTGCAGCCCTCGGTGAAGGTGCCATTGCCC CTGGCGGCTTCCCTCATGAGCTCAGAGCTTGCCCGCCATAGCAAGCGAGTCCGCATTGCC CCCAAGGTGCTGCTAGCTGAGGAGGGGATAGCTCCTCTTTCTTCTGCAGGACCAGGGAAA GAGGAGAAACTCCTGTTTGGAGAAGGGTTTTCTCCTTTGCTTCCAGTTCAGACTATCAAG GAGGAAGAAATCCAGCCTGGGGAGGAAATGCCACACTTAGCGAGACCCATCAAAGTGGAG AGCCCTCCCTTGGAAGAGTGGCCCTCCCCGGCCCCATCTTTCAAAGAGGAATCATCTCAC TCCTGGGAGGATTCGTCCCAATCTCCCACCCCAAGACCCAAGAAGTCCTACAGTGGGCTT AGGTCCCCAACCCGGTGTGTCTCGGAAATGCTTGTGATTCAACACAGGGAGAGGAGGGAG AGGAGCCGGTCTCGGAGGAAACAGCATCTACTGCCTCCCTGTGTGGATGAGCCGGAGCTG CTCTTCTCAGAGGGGCCCAGTACTTCCCGCTGGGCCGCAGAGCTCCCGTTCCCAGCAGAC TCCTCTGACCCTGCCTCCCAGCTCAGCTACTCCCAGGAAGTGGGAGGACCTTTTAAGACA CCCATTAAGGAAACGCTGCCCATCTCCTCCACCCCGAGCAAATCTGTCCTCCCCAGAACC CCTGAATCCTGGAGGCTCACGCCCCCAGCCAAAGTAGGGGGACTGGATTTCAGCCCAGTA CAAACCTCCCAGGGTGCCTCTGACCCCTTGCCTGACCCCCTGGGGCTGATGGATCTCAGC ACCACTCCCTTGCAAAGTGCTCCCCCCCTTGAATCACCGCAAAGGCTCCTCAGTTCAGAA CCCTTAGACCTCATCTCCGTCCCCTTTGGCAACTCTTCTCCCTCAGATATAGACGTCCCC AAGCCAGGCTCCCCGGAGCCACAGGTTTCTGGCCTTGCAGCCAATCGTTCTCTGACAGAA GGCCTGGTCCTGGACACAATGAATGACAGCCTCAGCAAGATCCTGCTGGACATCAGCTTT CCTGGCCTGGACGAGGACCCACTGGGCCCTGACAACATCAACTGGTCCCAGTTTATTCCT GAGCTACAGTAG Clone variation with respect to NM_021953.3 >OriGene 5' read for NM_021953 unedited
GTGTACCATTTTGTAATACAACTCACTATAGGCGGCCGCGAAATTCGCACGAGGGGTCCA CACTTGTGATTCTCAATGGAGAGTGAAAACGCAGATTCATAATGAAAACTAGCCCCCGTC GGCCACTGATTCTCAAAAGACGGAGGCTGCCCCTTCCTGTTCAAAATGCCCCAAGTGAAA CATCAGAGGAGGAACCTAAGAGATCCCCTGCCCAACAGGAGTCTAATCAAGCAGAGGCCT CCAAGGAAGTGGCAGAGTCCAACTCTTGCAAGTTTCCAGCTGGGATCAAGATTATTAACC ACCCCACCATGCCCAACACGCAAGTAGTGGCCATCCCCAACAATGCTAATATTCACAGCA TCATCACAGCACTGACTGCCAAGGGAAAAGAGAGTGGCAGTACTGGGCCCAACAAATTCA TCCTCATCACCTGTGGGGGAGCCCCAACTCAGCCTCCAGGACTCCGGCCTCAAACCCAAA CCAGCTATGATGCCAAAAGGACAGAAGTGACCCTGGAGACCTTGGGACCAAAACCTGCAG CTAGGGATGTGAATCTTCCTAGACCACCTGTAGCCCTTTGCGAGCAGAAACGGGAGACCT GTGCAGATGGTGAGGCACCAGGCTGCACTATCAACAATAGCCTATTCCACATCCAGTGGC CTTCGAAAGATGAGTCCTGATGGCCTGGGCCTCCCCAGCATCAAGCCAGAGATGGAGGGA AAGGAAAATTTGTCACCTCGGGCACACCACAGGTTAAGGTTGAAGAGCCTTCCGAAACCT CATCGTCCCGGAACAACCCTGTGTCTCGACGGACACCTCACTCTTACATGGGCATGAAAC CAATCGCCATCAACCCCATTGATAAGAAGCCCATGCACTTTGAAAACATCTATACGTCGC ATTGAGGACCCTCTTCCTTACTTAACCCCTTTGCCAGCCAC >OriGene 3' read for NM_021953 unedited
AATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGCATGTCCACCTTCGCTTTTATTGAGTA GTTAGTGTTCTCAAGCTGGCTCACACCCATGCGGTCAGCTGGGGCCTAGGGTGGCTCTTT GCAAAGCTGAGGGGCAAGCTAAGGAAGCCAGGCAGGTCAGGGGCCCTTTCGGCCTTCTCA AGCCTCCACCTGAGTTCTCGTCAATGCCAGTCTCCCTGGTATGATTGGGGACATTATCAG AGAAACATCTAATAGCGCACATCTGGGCACCCACACTCTGCTTCAGTTGCATCCATCCTC CCACCCCAAATTCAACTCCTGACCCAATACAAAAGACTTTTTTAACCAGGATTTCTTCTT GCAGGAAAGCTGACTTGGAAACACGGGGAGGTGGCAGGGAGGGGCAAAAAGGACTCTGGC AAGCAGATCCACTTGTCTGGGTCCCTGCAGTGAAGAACCCAAGATCCAGGTACCTCAGCC TGGAAGAAACCGTGCACTGCAGGTCTTCCCTTCTATCAAAACTAAAAGCAAGGAACAGAA GTCAATTGAAACCCCAGGTCATCCTACCCACCTTCTGGCAGTCTCTGGATAATGATCTAA GGAAATAAGCTTACATTTATAATTAGAGGATAATTTGGAGAATTTATACTATTTACACGG ACCACNCCTGCAAGATCAGGNAAGGGTAGAGACTGCTGGGCAGAGAATGGAAACAGGCTG GAGGGNTCCTAATCTCTTTTACCATTGGCTTAGTAGNTCCACCCCNCAGCTTCTGGCAGG GACAGCAGATGAATCAGATACTCCTGGGGAACACAAAGTCCCANCAGTGGCTATGGTGTG ACTGCTACTTTTGCATATCCAGGCACCAAGGAGCTATGAGGAGCANAANCAGTCCTGGCC TGCTGCCCTCACTCAAAGGCTCGGGNTGACCTGAGCCTTGGATGCCCCGGATGTTGGCAG CTTGNCCAAGGGCAAGCCAGGCCTTACTGACTCAGGATAACTGGACANNTGAGTGTCAGG CCCAAGGGTCCTTCC |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_021953 |
| Insert Size | 3460 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021953.2, NP_068772.2 |
| RefSeq Size | 3527 bp |
| RefSeq ORF | 2292 bp |
| Locus ID | 2305 |
| UniProt ID | Q08050 |
| Domains | FH |
| Protein Families | Transcription Factors |
| Gene Summary | The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. |
Citations (6)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression
,null,
Oncotarget
,PubMed ID 26243836
[FOXM1]
|
|
A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells
,Choudhary, P;Dodsworth, BT;Sidders, B;Gutteridge, A;Michaelides, C;Duckworth, JK;Whiting, PJ;Benn, CL;,
PLoS ONE
,PubMed ID 26121260
[FOXM1]
|
|
Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition
,Gormally, MV;Dexheimer, TS;Marsico, G;Sanders, DA;Lowe, C;Matak-Vinkovic, D;Michael, S;Jadhav, A;Rai, G;Maloney, DJ;Simeonov, A;Balasubramanian, S;,
Nat Commun
,PubMed ID 25387393
[FOXM1]
|
|
FOXM1 and androgen receptor co-regulate CDC6 gene transcription and DNA replication in prostate cancer cells
,Liu, Y;Gong, Z;Sun, L;Li, X;,
Biochim. Biophys. Acta
,PubMed ID 24583551
[FOXM1]
|
|
FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma
,Roberto Bellelli, Maria Domenica Castellone, Ginesa Garcia-Rostan, Clara Ugolini, Carmelo Nucera, Peter M Sadow, Tito Claudio Nappi, Paolo Salerno, Maria Carmela Cantisani, Fulvio Basolo, Tomas Alvarez Gago, Giuliana Salvatore, and Massimo Santoro,
Endocr. Relat. Cancer, Sep 2012; 19: 695 - 710.
[FOXM1]
|
|
Down-regulation of Forkhead Box M1 Transcription Factor Leads to the Inhibition of Invasion and Angiogenesis of Pancreatic Cancer Cells
,Z Wang, S Banerjee, D Kong, Y Li, and FH Sarkar,
Cancer Res. 2007 Sep 1;67(17):8293-300.
[FOXM1]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202246 | FOXM1 (Myc-DDK-tagged)-Human forkhead box M1 (FOXM1), transcript variant 2 |
CNY 5,592.00 |
|
| RC202246L1 | Lenti ORF clone of Human forkhead box M1 (FOXM1), transcript variant 2, Myc-DDK-tagged |
CNY 7,992.00 |
|
| RC202246L2 | Lenti ORF clone of Human forkhead box M1 (FOXM1), transcript variant 2, mGFP tagged |
CNY 7,992.00 |
|
| RC202246L3 | Lenti ORF clone of Human forkhead box M1 (FOXM1), transcript variant 2, Myc-DDK-tagged |
CNY 7,992.00 |
|
| RC202246L4 | Lenti ORF clone of Human forkhead box M1 (FOXM1), transcript variant 2, mGFP tagged |
CNY 7,992.00 |
|
| RG202246 | FOXM1 (tGFP-tagged) - Human forkhead box M1 (FOXM1), transcript variant 2 |
CNY 7,192.00 |
|
| SC323762 | FOXM1 (untagged)-Human forkhead box M1 (FOXM1), transcript variant 2 |
CNY 5,600.00 |
