Fibrinogen beta chain (FGB) (NM_005141) Human Untagged Clone

CAT#: SC112673

FGB (untagged)-Human fibrinogen beta chain (FGB), transcript variant 1



  "NM_005141" in other vectors (7)

CNY 3,656.00

CNY 7,890.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit Polyclonal Anti-FGB Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms HEL-S-78p
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_005141, the custom clone sequence may differ by one or more nucleotides


ATGAAAAGGATGGTTTCTTGGAGCTTCCACAAACTTAAAACCATGAAACATCTATTATTGCTACTATTGT
GTGTTTTTCTAGTTAAGTCCCAAGGTGTCAACGACAATGAGGAGGGTTTCTTCAGTGCCCGTGGTCATCG
ACCCCTTGACAAGAAGAGAGAAGAGGCTCCCAGCCTGAGGCCTGCCCCACCGCCCATCAGTGGAGGTGGC
TATCGGGCTCGTCCAGCCAAAGCAGCTGCCACTCAAAAGAAAGTAGAAAGAAAAGCCCCTGATGCTGGAG
GCTGTCTTCACGCTGACCCAGACCTGGGGGTGTTGTGTCCTACAGGATGTCAGTTGCAAGAGGCTTTGCT
ACAACAGGAAAGGCCAATCAGAAATAGTGTTGATGAGTTAAATAACAATGTGGAAGCTGTTTCCCAGACC
TCCTCTTCTTCCTTTCAGTACATGTATTTGCTGAAAGACCTGTGGCAAAAGAGGCAGAAGCAAGTAAAAG
ATAATGAAAATGTAGTCAATGAGTACTCCTCAGAACTGGAAAAGCACCAATTATATATAGATGAGACTGT
GAATAGCAATATCCCAACTAACCTTCGTGTGCTTCGTTCAATCCTGGAAAACCTGAGAAGCAAAATACAA
AAGTTAGAATCTGATGTCTCAGCTCAAATGGAATATTGTCGCACCCCATGCACTGTCAGTTGCAATATTC
CTGTGGTGTCTGGCAAAGAATGTGAGGAAATTATCAGGAAAGGAGGTGAAACATCTGAAATGTATCTCAT
TCAACCTGACAGTTCTGTCAAACCGTATAGAGTATACTGTGACATGAATACAGAAAATGGAGGATGGACA
GTGATTCAGAACCGTCAAGACGGTAGTGTTGACTTTGGCAGGAAATGGGATCCATATAAACAGGGATTTG
GAAATGTTGCAACCAACACAGATGGGAAGAATTACTGTGGCCTACCAGGTGAATATTGGCTTGGAAATGA
TAAAATTAGCCAGCTTACCAGGATGGGACCCACAGAACTTTTGATAGAAATGGAGGACTGGAAAGGAGAC
AAAGTAAAGGCTCACTATGGAGGATTCACTGTACAGAATGAAGCCAACAAATACCAGATCTCAGTGAACA
AATACAGAGGAACAGCCGGTAATGCCCTCATGGATGGAGCATCTCAGCTGATGGGAGAAAACAGGACCAT
GACCATTCACAACGGCATGTTCTTCAGCACGTATGACAGAGACAATGACGGCTGGTTAACATCAGATCCC
AGAAAACAGTGTTCTAAAGAAGACGGTGGTGGATGGTGGTATAATAGATGTCATGCAGCCAATCCAAACG
GCAGATACTACTGGGGTGGACAGTACACCTGGGACATGGCAAAGCATGGCACAGATGATGGTGTAGTATG
GATGAATTGGAAGGGGTCATGGTACTCAATGAGGAAGATGAGTATGAAGATCAGGCCCTTCTTCCCACAG
CAATAG


>OriGene 5' read for NM_005141 unedited
NCGGTCAGAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGACATGG
CAAAGCATGGCACAGATGATGGTGTAGTATGGATGAATTGGCTGCATGACATCTATTATA
CCACCATCCACCACCGTCTTCTTTAGAACACTGTTTTCTGGGATCTGATGTTAACCAGCC
GTCATTGTCTCTGTCATACGTGCTGAAGAACATGCCGTTGTGAATGGTCATGGTCCTGTT
TTCTCCCATCAGCTGAGATGCTCCATCCATGAGGGCATTACCGGCTGTTCCTCTGTATTT
GTTCACTGAGATCTGGTATTTGTTGGCTTCATTCTGTACAGTGAATCCTCCATAGTGAGC
CTTTACTTTGTCTCCTTTCCAGTCCTCCATTTCTATCAAAAGTTCTGTGGGTCCCATCCT
GGTAAGCTGGCTAATTTTATCATTTCCAAGCCAATATTCACCTGGTAGGCCACAGTAATT
CTTCCCATCTGTGTTGGTTGCAACATTTCCAAATCCCTGTTTATATGGATCCCATTTCCT
GCCAAAGTCAACACTACCGTCTTGACGGTTCTGGTTTCTTGGAGCTTCCACAAACTTAAA
ACCATGAAACATCTATTATTGCTACTATTGTGTGTTTTTCTAGTTAAGTCCCAAGGTGTC
AACGACAATGAGGAGGGTTTCTTCAGTGCCCGTGGTCATCGACCCCTTGACAAGAAGAGA
GAGAAGCTCCCAGCCTGAGGCCTGCCCCACCGCCCATCAGTGGGAGTGGCTATCGGGCTC
GTCCAGCCAAGCAGCTGCCACTCAAAANAAGTAGAAAGAAAAGCCCTGATGCTGNAGGCT
GTCTTCACGCTGACCCANACCTGGGGGTGTTGTGTCCTACAGGATGTCAGTTGCAAG
>OriGene 3' read for NM_005141 unedited
NTCTTACTTGNCCGCGGCCGCAATCTANNGATCGGTTTTTTTTTTTTTTTTTTTTTATTG
CAACAAAGTCTGGTTTAATTAATAAATCTTTTTGGAAGTTTTCTTTGACAGATCCTACAT
AAATAAATATAGTTTTAAAAGTGGACTTTTAAACATCAGTTTTTCCTTTCCGTCATGGTT
TTCCTACGACAAGGATAAAAGACCCCTCTTCCTTATTTGAAAATTCTCGCAATCAACTAG
AACTGAAATTATGAACACCAACTCTGTCAAAACTATACTTTTGTTACTTCTTGGTGAGCA
AGAGAAATGAAGAAAACAAAAGAAAATCATGTGCTATTTTAATGTAATTTATCCTATACT
TTTTTCAAAAAGTCACACTCACGTCTGCTTGAGAGTTTTAGAGGAATATAATGTATGAAA
GAAAATTCCAATAACATAATGTACAAAAATGTTGTCACATACAGAAGAGCAAAAATCTAC
GTATTGGGGACTATTGCTGTGGGAAGAAGGGCCTGATCTTCATACTCATCTTCCTCATTG
AGTACCATGACCCCTTCCAATTCATCCATACTACACCATCATCTGTGCCATGCTTTGCCA
TGTCCCAGGTGTACTGTCCACCCCAGTAGATCTGCTGAAATAGGGNNCCCCCCTTCCNCC
ACTTATTTTACCCACCCTTCCCACCCCGGTTTTTTTTAAAACACTGTTTTCTTGGGATCT
GATGTTAACCCAGCCGTCATTGTCTCTGGCATACGTGCTGAAGAACATGCCTTGTGAATG
GCATGGCCCTGTTTTCTCCCTCAGCTGAGATGCTCATCCATGAGGCATTACCGGCTGTTC
CTCTGTATTTGTCACTGAAATCTGTTATTGTTGGCTTCTTCTGTACATGAATCCTCCATA
NGAGCCTTTACTTGNCTCCTTTCAGCCTCCTTTCTATCAAAGTCTGGGGGC
Restriction Sites NotI-NotI     
ACCN NM_005141
Insert Size 2570 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_005141.2, NP_005132.2
RefSeq Size 1949 bp
RefSeq ORF 1476 bp
Locus ID 2244
UniProt ID P02675
Domains FBG
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades
Gene Summary The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Fibrinogen serves key roles in hemostasis and antimicrobial host defense. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq, Aug 2020]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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