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GLP2R (NM_004246) Human Untagged Clone
CAT＃: SC111108
GLP2R (untagged)-Human glucagon-like peptide 2 receptor (GLP2R)
CN¥ 4,128.00
CN¥ 8,840.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_004246, the custom clone sequence may differ by one or more nucleotides
ATGAAGCTGGGATCGAGCAGGGCAGGGCCTGGGAGAGGAAGCGCGGGACTCCTGCCTGGCGTCCACGAGC TGCCCATGGGCATCCCTGCCCCCTGGGGGACCAGTCCTCTCTCCTTCCACAGGAAGTGCTCTCTCTGGGC CCCTGGGAGGCCCTTCCTCACTCTGGTCCTGCTGGTTTCCATCAAGCAAGTTACAGGATCCCTCCTTGAG GAAACGACTCGGAAGTGGGCTCAGTACAAACAGGCATGTCTGAGAGACTTACTCAAGGAACCTTCTGGCA TATTTTGTAACGGGACATTTGATCAGTACGTGTGTTGGCCTCATTCTTCTCCTGGAAATGTCTCTGTACC CTGCCCTTCATACTTACCTTGGTGGAGTGAAGAGAGCTCAGGAAGGGCCTACAGACACTGCTTGGCTCAG GGGACTTGGCAGACGATAGAGAACGCCACGGATATTTGGCAGGATGACTCCGAATGCTCCGAGAACCACA GCTTCAAGCAAAACGTGGACCGTTATGCCTTGCTGTCAACCTTGCAGCTGATGTACACCGTGGGATACTC CTTCTCTCTTATCTCCCTCTTCCTGGCTCTCACCCTCCTCTTGTTTCTTCGAAAACTCCACTGCACGCGC AACTACATCCACATGAACTTGTTTGCTTCTTTCATCCTGAGAACCCTGGCTGTACTGGTGAAGGACGTCG TCTTCTACAACTCTTACTCCAAGAGGCCTGACAATGAGAATGGGTGGATGTCCTACCTGTCAGAGATGTC CACCTCCTGCCGCTCAGTCCAGGTTCTCTTGCATTACTTTGTGGGTGCCAATTACTTATGGCTGCTGGTT GAAGGCCTCTACCTCCACACGCTGCTGGAGCCCACAGTGCTTCCTGAGAGGCGGCTGTGGCCCAGATACC TGCTGTTGGGTTGGGCCTTCCCTGTGCTATTTGTTGTACCCTGGGGTTTCGCCCGTGCACACCTGGAGAA CACAGGGTGCTGGACAACAAATGGGAATAAGAAAATCTGGTGGATCATCCGAGGACCCATGATGCTCTGT GTAACAGTCAATTTCTTCATCTTCCTGAAAATTCTCAAGCTTCTCATTTCTAAGCTCAAAGCTCATCAAA TGTGCTTCAGAGATTATAAATACAGATTGGCAAAATCAACACTGGTCCTCATTCCTTTATTGGGCGTTCA TGAGATCCTCTTCTCTTTCATCACTGATGATCAAGTTGAAGGATTTGCAAAACTTATACGACTTTTCATT CAGTTGACACTGAGCTCCTTTCATGGGTTCCTGGTGGCCTTGCAGTATGGTTTTGCCAATGGAGAAGTGA AGGCTGAGCTGCGGAAATACTGGGTCCGCTTCTTGCTAGCCCGCCACTCAGGCTGCAGAGCCTGTGTCCT GGGGAAGGACTTCCGGTTCCTAGGAAAATGTCCCAAGAAGCTCTCGGAAGGAGATGGCGCTGAGAAGCTT CGGAAGCTGCAGCCCTCACTTAACAGTGGGCGGCTCCTACATCTAGCCATGCGAGGTCTTGGGGAGCTGG GCGCCCAGCCCCAACAGGACCATGCACGCTGGCCCCGGGGCAGCAGCCTGTCCGAGTGCAGTGAGGGGGA TGTCACCATGGCCAACACCATGGAGGAGATTCTGGAAGAGAGTGAGATCTAG >OriGene 5' read for NM_004246 unedited
GATTTTGTATACGACTCACTATAGGGCGGCCCGCGATTCGGCACGAGCTCAGACACTCTC GGCGCAGCGTGGAGAGGATTTGTGCAAACATTTCCTCTGTGGACCAAGAGGAATGCAAGA GGAGGCTGCCTGCGGTGCATCTTGGACGGCTAGAGAGATGTACCCCTACTTGTGAAGGTG CACGAGGAAGATGAAGCTGGGATCGAGCAGGGCAGGGCCTGGGAGAGGAAGCGCGGGACT CCTGCCTGGCGTCCACGAGCTGCCCATGGGCATCCCTGCCCCCTGGGGGACCAGTCCTCT CTCCTTCCACAGGAAGTGCTCTCTCTGGGCCCCTGGGAGGCCCTTCCTCACTCTGGTCCT GCTGGTTTCCATCAAGCAAGTTACAGGATCCCTCCTTGAGGAAACGACTCGGAAGTGGGC TCAGTACAAACAGGCATGTCTGAGAGACTTACTCAAGGAACCTTCTGGCATATTTTGTAA CGGGACATTTGATCAGTACGTGTGTTGGCCTCATTCTTCTCCTGGAAATGTCTCTGTACC CTGCCCTTCATACTTACCTTGGTGGAGTGAAGAGAGCTCAGGAAGGGCCTACAGACACTG CTTGGCTCAGGGGACTTGGCAGACGATAGAGAACGCCACGGATATTTGGCAGGATGACTC CGAGTGCTCCGAGAACCACAGCTTCAAGCAAAACGTGGATCGTTATGCCTTGCTGTCAAC CTTGCAGCTGATGTACACCGTGGGATACTCCTTCTCTCTTATCTCCCTCTTCCTGGCTCT CACCCTCCTCTTGNTTCTTCGAAAACTCCACTGCACGCGCAACTACATCCACATGAACTT GNTTGCTTCTTTCATNCTGAGAACCCTGNCTGTACTGGTGAAGGACGTCGTCTTCTACAA CTCTACTNCAGAGGCCTGACATGAGATGGNTGGATGTCCTACTGTCAGAGAGTCCACTCC TGCGCTCAGTCAGNTCTCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004246 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004246.1, NP_004237.1 |
| RefSeq Size | 1662 bp |
| RefSeq ORF | 1662 bp |
| Locus ID | 9340 |
| UniProt ID | O95838 |
| Domains | 7tm_2, HormR |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice.
,null,
British journal of pharmacology
,PubMed ID 36683195
[GLP2R]
|
|
N‐terminal alterations turn the gut hormone GLP‐2 into an antagonist with gradual loss of GLP‐2 receptor selectivity towards more GLP‐1 receptor interaction
,null,
British Journal of Pharmacology
,PubMed ID 35523760
[GLP2R]
|
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Other Versions
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|---|---|---|---|
| RC220745 | GLP2R (Myc-DDK-tagged)-Human glucagon-like peptide 2 receptor (GLP2R) |
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| RC220745L1 | Lenti ORF clone of Human glucagon-like peptide 2 receptor (GLP2R), Myc-DDK-tagged |
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| RC220745L2 | Lenti ORF clone of Human glucagon-like peptide 2 receptor (GLP2R), mGFP tagged |
CN¥ 6,460.00 |
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| RC220745L3 | Lenti ORF clone of Human glucagon-like peptide 2 receptor (GLP2R), Myc-DDK-tagged |
CN¥ 6,460.00 |
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| RC220745L4 | Lenti ORF clone of Human glucagon-like peptide 2 receptor (GLP2R), mGFP tagged |
CN¥ 6,460.00 |
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| RG220745 | GLP2R (tGFP-tagged) - Human glucagon-like peptide 2 receptor (GLP2R) |
CN¥ 5,720.00 |
