SLP76 (LCP2) (NM_005565) Human Untagged Clone

CAT#: SC110940

LCP2 (untagged)-Human lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) (LCP2)



  "NM_005565" in other vectors (7)

CNY 5,960.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


LCP2 mouse monoclonal antibody, clone OTI7E8
    • 100 ul

CNY 1,999.00
CNY 3,600.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms IMD81; SLP-76; SLP76
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC110940 sequence for NM_005565 edited (data generated by NextGen Sequencing)
ATGGCACTGAGGAATGTGCCCTTTCGCTCAGAGGTCCTGGGCTGGGACCCCGACAGCCTT
GCTGACTATTTCAAGAAGCTCAACTATAAGGACTGTGAGAAGGCAGTGAAGAAGTACCAC
ATCGATGGGGCTCGCTTCTTGAACCTGACAGAAAATGACATCCAGAAGTTCCCCAAGCTC
CGGGTGCCGATTCTCAGTAAGTTAAGTCAGGAAATCAACAAGAACGAAGAGAGGAGGAGC
ATCTTCACACGCAAACCCCAAGTCCCGCGGTTTCCTGAAGAGACAGAAAGCCACGAAGAG
GACAATGGGGGCTGGTCGTCCTTTGAAGAAGACGATTATGAAAGTCCCAATGATGACCAG
GATGGGGAGGATGATGGAGACTATGAGTCCCCCAATGAGGAGGAAGAGGCACCCGTGGAA
GATGACGCGGATTATGAGCCGCCACCCTCCAATGACGAGGAAGCTCTGCAGAACTCCATC
CTGCCTGCCAAGCCTTTCCCCAACTCCAACTCCATGTACATCGACCGGCCCCCCTCTGGG
AAAACCCCCCAGCAGCCTCCTGTGCCCCCCCAGAGACCGATGGCCGCCCTCCCGCCCCCA
CCAGCCGGCCGGAATCACTCGCCACTGCCCCCACCCCAGACCAACCACGAAGAACCCAGC
AGAAGCAGAAACCACAAAACGGCAAAGCTCCCTGCTCCTTCAATAGACAGAAGCACGAAA
CCTCCTCTAGATCGTTCATTAGCTCCGTTTGATAGAGAACCCTTCACACTAGGAAAGAAA
CCACCATTTTCTGACAAGCCCTCGATTCCAGCGGGAAGGTCACTCGGGGAGCATTTACCC
AAGATTCAAAAGCCTCCTTTACCACCGACCACGGAAAGACATGAAAGGAGCAGCCCCCTG
CCAGGGAAGAAGCCACCTGTGCCAAAGCATGGATGGGGACCAGACAGAAGAGAGAATGAT
GAAGATGATGTGCATCAGAGACCTTTGCCCCAGCCAGCACTACTTCCTATGAGCTCCAAC
ACTTTCCCTTCAAGATCTACTAAGCCAAGTCCCATGAACCCTCTCCCATCCTCTCACATG
CCTGGAGCATTCTCAGAAAGTAACAGCAGTTTTCCACAGAGTGCCTCCCTGCCACCATAC
TTCTCTCAAGGCCCTAGCAACAGACCACCTATCAGAGCCGAAGGCAGAAACTTCCCCTTG
CCACTTCCAAACAAACCTCGGCCCCCATCCCCCGCGGAGGAAGAGAATTCATTAAATGAA
GAGTGGTACGTTTCTTATATTACCCGACCAGAGGCAGAAGCTGCTCTTAGAAAGATAAAC
CAGGATGGCACATTTCTGGTCAGAGACAGCTCTAAAAAAACAACAACCAATCCATATGTC
CTCATGGTGTTGTACAAAGATAAAGTTTACAACATCCAGATCCGTTATCAGAAGGAAAGT
CAAGTTTACTTGTTGGGAACTGGACTCCGAGGGAAAGAGGACTTTCTGTCTGTGTCAGAT
ATTATTGACTACTTCAGGAAAATGCCACTTCTGCTCATTGATGGGAAAAACCGAGGTTCC
AGATACCAGTGCACATTAACGCATGCTGCAGGGTACCCATAG

Clone variation with respect to NM_005565.3
726 c=>t
>OriGene 5' read for NM_005565 unedited
GGGTGCACATTAGGNATACGATTCCTATAGGCGGCCCGCGAATTCGCACGAGAAAACTCG
GCTCCAACAGGGGTGTTCCACAGGGTAGCTGGGAGTTGGAAGAGCCAAGAACGCCTCCGA
GCTCTGGATTTGAGCTTCTCTGCCCATGGGTGAAGCGCCCATGCTCAGCTTGTGAGCTTC
TTCCCGGGAGAGCAGCCATGGCACTGAGGAATGTGCCCTTTCGCTCAGAGGTCCTGGGCT
GGGACCCCGACAGCCTTGCTGACTATTTCAAGAAGCTCAACTATAAGGACTGTGAGAAGG
CAGTGAAGAAGTACCACATCGATGGGGCTCGCTTCTTGAACCTGACAGAAAATGACATCC
AGAAGTTCCCCAAGCTCCGGGTGCCGATTCTCAGTAAGTTAAGTCAGGAAATCAACAAGA
ACGAAGAGAGGAGGAGCATCTTCACACGCAAACCCCAAGTCCCGCGGTTTCCTGAAGAGA
CAGAAAGCCACGAAGAGGACAATGGGGGCTGGTCGTCCTTTGAAGAAGACGATTATGAAA
GTCCCAATGATGACCAGGATGGGGAGGATGATGGAGACTATGAGTCCCCCAATGAGGAGG
AAGAGGCACCCGTGGAAGATGACGCGGATTATGACCCGCCACCCTCCAATGACCAGGAAG
CTCTGCAGAACTCCATCCTGCCTGCCAAGCCTTTCCCCAACTTCAACTCCATGTCCATTC
GACCGGCCCCCCTCTTGGGAAAACCCCCCAAAAGCCTCTCTGCGCCCCACCCACAGACCC
GAGGGCCCGCCCTCCCCCCCCCCACCATCCGGCCGGAAAACACTCGGCCCTTGCCTCCAC
TCCCATCCACCCACGAACAATCCCCCTCCAACATCAACCCCCCAACGCGTCAGCCCCCCT
CGCCCTTCCACTCCTCACAAATCCCCCCG
>OriGene 3' read for NM_005565 unedited
GCGGCCGCTTTCTAGTATCGAGTTTTTTTTTTTTTTTTTTAAAGCAAAAAACTATTTTAA
TCCCAGAAGTTATCTCAACATGCATTTGTCTTTTCATAAAAAAATTACGTAAAAATCCCC
CCAGGAAAAAATACTAAATAAGAGTGAAATTATATTTTTGAAGCCTCTTAAATTATTGCT
GCTGAGAAAACGAGGTTTAGTGATTTTCAAATTACATGTATAAAACTAATGAATGCCTCT
GACTGACAGAGGTTTGGCTGTAAAAAACAAATCAGTTTTATGTGACACCAATAACTATTA
CTGTTTCAGTGTTTTAAAACTTGCCCCAAATTGTTTCTGTAGCTGTGTAAACTACTGTAT
TTTGAAATGGGCATTAAATAATCTTTTAAAAAATGAATTATTACAGTGCACTACTAGACT
TCAAGTGTGAACATGACTCATGCACTTTACAAACATTGAAGAAGATTAAATAAATTATGG
GATAGTCGACAGTCTTCATTTCAAACACTGTTTTTAAAGGAAAGGATAAAACCCTTGTGT
TCATGGGGAGGGGTTCAGTTCATTCCTAAGTGTTTGTCCATTGACCAAAGCTGATGGATC
TCGTGTCGGCAACAGAGGCAGGAGGACGGTTCATTTGCTCGGCTAAACTTGCTATGGGTA
CCCTGCATCACGCGTCATTGTGCCCTGGTATTCGGGAACCTCGGGTGTTCCCCTTATAGA
TCAAAAGTGGCCTTTTCCTGAATCTGGCATTATTTCTGACCCAGACAAAAACTCTTCTTC
TTTGTATCCACTCGCAATATCTAACCCTGTCTTCCTCTTAAACCGATCTTTATGCTTATT
CCTTATTTTCTCCCTCCCGTAGGCATTGTTCCGTCGCCCTCTCTTACACTCTCCTCCCTA
TATCGCCTCTCTCGACCCTTCTAATATCCACTTCTCTCGACGCCTCTTATGTACATTCCT
TTCC
Restriction Sites NotI-NotI     
ACCN NM_005565
Insert Size 2390 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_005565.3, NP_005556.1
RefSeq Size 2472 bp
RefSeq ORF 1602 bp
Locus ID 3937
UniProt ID Q13094
Domains SH2, SAM
Protein Pathways Fc epsilon RI signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway
Gene Summary This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability. [provided by RefSeq, Nov 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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