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DPP8 (NM_197961) Human Untagged Clone
CAT＃: SC110497
DPP8 (untagged)-Human dipeptidyl-peptidase 8 (DPP8), transcript variant 4
CNY 6,208.00
| Cited in 1 publication. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DP8; DPRP-1; DPRP1; MST097; MSTP097; MSTP135; MSTP141 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC110497 sequence for NM_197961 edited (data generated by NextGen Sequencing)
ATGTGGAAGAGATCTGAGCAGATGAAAATAAAATCAGGAAAATGCAACATGGCAGCAGCA ATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATATT GAATCACAGGATCGGCCTAAATTGGAGCCTTTTTATGTTGAGCGGTATTCCTGGAGTCAG CTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGCTACATGATGGCTAAGGCACCA CATGATTTCATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTAT TACCTTGCCATGTCTGGTGAGAACAGAGAAAATACACTGTTTTATTCTGAAATTCCCAAA ACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAGCCTCTTTTGGATCTTTTTCAG GCAACACTGGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGAGAAAGAAAACGC ATTGGAACAGTCGGAATTGCTTCTTACGATTATCACCAAGGAAGTGGAACATTTCTGTTT CAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGGCCACAAGGATTTACGCAACAA CCTTTAAGGCCCAATCTAGTGGAAACTAGTTGTCCCAACATACGGATGGATCCAAAATTA TGCCCTGCTGATCCAGACTGGATTGCTTTTATACATAGCAACGATATTTGGATATCTAAC ATCGTAACCAGAGAAGAAAGGAGACTCACTTATGTGCACAATGAGCTAGCCAACATGGAA GAAGATGCCAGATCAGCTGGAGTCGCTACCTTTGTTCTCCAAGAAGAATTTGATAGATAT TCTGGCTATTGGTGGTGTCCAAAAGCTGAAACAACTCCCAGTGGTGGTAAAATTCTTAGA ATTCTATATGAAGAAAATGATGAATCTGAGGTGGAAATTATTCATGTTACATCCCCTATG TTGGAAACAAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAA GTCACTTTTAAGATGTCAGAAATAATGATTGATGCTGAAGGAAGGATCATAGATGTCATA GATAAGGAACTAATTCAACCTTTTGAGATTCTATTTGAAGGAGTTGAATATATTGCCAGA GCTGGATGGACTCCTGAGGGAAAATATGCTTGGTCCATCCTACTAGATCGCTCCCAGACT CGCCTACAGATAGTGTTGATCTCACCTGAATTATTTATCCCAGTAGAAGATGATGTTATG GAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTGACGCCACTAATTATCTATGAA GAAACAACAGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTCAC GAAGAGGAAATTGAGTTTATTTTTGCCTCTGAATGCAAAACAGGTTTCCGTCATTTATAC AAAATTACATCTATTTTAAAGGAAAGCAAATATAAACGATCCAGTGGTGGGCTGCCTGCT CCAAGTGATTTCAAGTGTCCTATCAAAGAGGAGATAGCAATTACCAGTGGTGAATGGGAA GTTCTTGGCCGGCATGGATCTAATATCCAAGTTGATGAAGTCAGAAGGCTGGTATATTTT GAAGGCACCAAAGACTCCCCTTTAGAGCATCACCTGTACGTAGTCAGTTACGTAAATCCT GGAGAGGTGACAAGGCTGACTGACCGTGGCTACTCACATTCTTGCTGCATCAGTCAGCAC TGTGACTTCTTTATAAGTAAGTATAGTAACCAGAAGAATCCACACTGTGTGTCCCTTTAC AAGCTATCAAGTCCTGAAGATGACCCAACTTGCAAAACAAAGGAATTTTGGGCCACCATT TTGGATTCAGCAGGTCCTCTTCCTGACTATACTCCTCCAGAAATTTTCTCTTTTGAAAGT ACTACTGGATTTACATTGTATGGGATGCTCTACAAGCCTCATGATCTACAGCCTGGAAAG AAATATCCTACTGTGCTGTTCATATATGGTGGTCCTCAGGTGCAGTTGGTGAATAATCGG TTTAAAGGAGTCAAGTATTTCCGCTTGAATACCCTAGCCTCTCTAGGTTATGTGGTTGTA GTGATAGACAACAGGGGATCCTGTCACCGAGGGCTTAAATTTGAAGGCGCCTTTAAATAT AAAATGGTTGCTATTGCTGGGGCCCCAGTCACTCTGTGGATCTTCTATGATACAGGATAC ACGGAACGTTATATGGGTCACCCTGACCAGAATGAACAGGGCTATTACTTAGGATCTGTG GCCATGCAAGCAGAAAAGTTCCCCTCTGAACCAAATCGTTTACTGCTCTTACATGGTTTC CTGGATGAGAATGTCCATTTTGCACATACCAGTATATTACTGAGTTTTTTAGTGAGGGCT GGAAAGCCATATGATTTACAGATCTATCCTCAGGAGAGACACAGCATAAGAGTTCCTGAA TCGGGAGAACATTATGAACTGCATCTTTTGCACTACCTTCAAGAAAACCTTGGATCACGT ATTGCTGCTCTAAAAGTGATATAA Clone variation with respect to NM_197961.2 >OriGene 5' read for NM_197961 unedited
TAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCCGCTGCTACTGCCGCC GCTGCTTCTTAGTGCCGCGTTCGCCGCCTGGGTTGTCACCGGCGCCGCCGCCGAGGAAGC CACTGCAACCAGGACCGGAGTGGAGGCGGCGCAGCATGAAGCGGCGCAGGCCCGCTCCAT AGCGCACGTCGGGACGGTCCGGGCGGGGCCGGGGGGAAGGCTTTGATGGTGAGGAAAGGA AAGATTCCTGTGAGAAGAGCAGGATGAGCAGAGGGATTCTATGCTTGAAGTCGAGTCACT TGAAAAAGATCTCTTTGAATGTGGAAGAGATCTGAGCAGATGAAAATAAAATCAGGAAAA TGCAACATGGCAGCAGCAATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCG GACTGTGAGGAGAATATTGAATCACAGGATCGGCCTAAATTGGAGCCTTTTTATGTTGAG CGGTATTCCTGGAGTCAGCTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGCTAC ATGATGGCTAAGGCACCACATGATTTCATGTTTGTGAAGAGGAATGATCCAGATGGACCT CATTCAGACAGAATCTATTACCTTGCCATGGGTCTGGTGAGAACAGAGAAAATACACTGG TTTTATTCTGGAATTCCCAAAACTATAATAGAANCAGCAGTCTTAATGCTCTCTGGAAGC CTCTTTTTGGTATCTTTTCAGGCACACTGGCTATGGGAATGGATTCTCGAGAAGAAGACT ATTAAGAGAAAGAAACGCATGGGACAGTCGGAATTGCTTTTACATATCCCCNGGGAGTGG ACCTTTTCTGTCAGACCCGGGTGGGGATTTATACGAAAAAGGGGGGGCCCAGGTTACCAC CCCCTTAGGCATCTAGAGCAACNTTGCATCCGGGGGGGCCAATTGCC >OriGene 3' read for NM_197961 unedited
GNANGAGCACTGGGGNAGGGTCACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTA TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAGTAATTCTTATGGT ATTGCTGGGTCTCTCAGGAATATGTATCATTTGATTTTGAGCATGTGGGGTTAAGGTATT AGATTACTACCACAAACCGTAGACCCCTGCATGGCACCACATTTATTTTCAGGAGTAGAT GTTACATGGCAGGTATCAAAATGTGATGATCAATTCTGTGTTTTCTGTTGATTAAACCTC CTCATTTGGTTAAATAGCCAGTGTATACCAGAGAGTTCTACACAGGTCAAAATTATATCA CTTTTAGAGCAGCAATACGTGATCCAAGGTTTTCTTGAAGGTAGTGCAAAAGATGCAGTT CATAATGTTCTCCCGATTCAGGAACTCTTATGCTGTGTCTCTCCTGAGGATAGATCTGTA AATCATATGGCTTTCCAGCCCTCACTAAAAAACTCAATAATATACTGGTATGTGCAAAAT GGACATTCTCATCCNGGAAACCATGTNAAAACACTAAACGATTTGGTTCAAAGGGGAACT TTTCTGCTTGCATGGCCACAAATCCTTAATAATAACCCCTGTTATTTCTGGTCAGGGTAA CCCATAAAACATTCCATGTAACCTGTATCAAANAAAATCCACATATTGATTGGGGCCCCC GCATAAAACCCTTAAAATATCGACACTCGCATTATGCCCCCAAGAAAGGTATACTTCTTA CACCACCCTGTATCCCCCCCCCTCCACTTCATTGAATCATTACCGCAACCTATTATTGGA CTCCCCCCCCAATATTCATTGTTTGTGGCGCGGGTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_197961 |
| Insert Size | 3300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_197961.1, NP_932065.1 |
| RefSeq Size | 3129 bp |
| RefSeq ORF | 2544 bp |
| Locus ID | 54878 |
| UniProt ID | Q6V1X1 |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Gene Summary | This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (4) contains an alternate exon in the 5' UTR and 5' coding region and lacks an exon in the 3' coding region compared to variant 1. These diferences result in the use of an alternate start codon compared to variant 1. The encoded isoform (4) is shorter and has a distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Selective Inhibition of Fibroblast Activation Protein Protease Based on Dipeptide Substrate Specificity
,Conrad Yap Edosada, Clifford Quan, Christian Wiesmann, Thuy Tran, Dan Sutherlin, Mark Reynolds, J. Michael Elliott, Helga Raab, Wayne Fairbrother, and Beni B. Wolf,
J. Biol. Chem., Vol. 281, Issue 11, 7437-7444, March 17, 2006
[DPP8]
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| RC205236L1 | Lenti ORF clone of Human dipeptidyl-peptidase 8 (DPP8), transcript variant 4, Myc-DDK-tagged |
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| RC205236L2 | Lenti ORF clone of Human dipeptidyl-peptidase 8 (DPP8), transcript variant 4, mGFP tagged |
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| RC205236L3 | Lenti ORF clone of Human dipeptidyl-peptidase 8 (DPP8), transcript variant 4, Myc-DDK-tagged |
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| RC205236L4 | Lenti ORF clone of Human dipeptidyl-peptidase 8 (DPP8), transcript variant 4, mGFP tagged |
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| RG205236 | DPP8 (tGFP-tagged) - Human dipeptidyl-peptidase 8 (DPP8), transcript variant 4 |
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