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Ubiquilin (UBQLN1) (NM_013438) Human Untagged Clone
CAT＃: SC110414
UBQLN1 (untagged)-Human ubiquilin 1 (UBQLN1), transcript variant 1
CNY 2,950.00
| Cited in 1 publication. |
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DA41; DSK2; PLIC-1; UBQN; XDRP1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC110414 sequence for NM_013438 edited (data generated by NextGen Sequencing)
ATGGCCGAGAGTGGTGAAAGCGGCGGTCCTCCGGGCTCCCAGGATAGCGCCGCCGGAGCC GAAGGTGCTGGCGCCCCCGCGGCCGCTGCCTCCGCGGAGCCCAAAATCATGAAAGTCACC GTGAAGACCCCGAAGGAAAAGGAGGAATTCGCCGTGCCCGAGAATAGCTCCGTCCAGCAG TTTAAGGAAGAAATCTCTAAACGTTTTAAATCACATACTGACCAACTTGTGTTGATATTT GCTGGAAAAATTTTGAAAGATCAAGATACCTTGAGTCAGCATGGAATTCATGATGGACTT ACTGTTCACCTTGTCATTAAAACACAAAACAGGCCTCAGGATCATTCAGCTCAGCAAACA AATACAGCTGGAAGCAATGTTACTACATCATCAACTCCTAATAGTAACTCTACATCTGGT TCTGCTACTAGCAACCCTTTTGGTTTAGGTGGCCTTGGGGGACTTGCAGGTCTGAGTAGC TTGGGTTTGAATACTACCAACTTCTCTGAACTACAGAGTCAGATGCAGCGACAACTTTTG TCTAACCCTGAAATGATGGTCCAGATCATGGAAAATCCCTTTGTTCAGAGCATGCTCTCA AATCCTGACCTGATGAGACAGTTAATTATGGCCAATCCACAAATGCAGCAGTTGATACAG AGAAATCCAGAAATTAGTCATATGTTGAATAATCCAGATATAATGAGACAAACGTTGGAA CTTGTCAGGAATCCAGCAATGATGCAGGAGATGATGAGGAACCAGGACCGAGCTTTGAGC AACCTAGAAAGCATCCCAGGGGGATATAATGCTTTAAGGCGCATGTACACAGATATTCAG GAACCAATGCTGAGTGCTGCACAAGAGCAGTTTGGTGGTAATCCATTTGCTTCCTTGGTG AGCAATACATCCTCTGGTGAAGGTAGTCAACCTTCCCGTACAGAAAATAGAGATCCACTA CCCAATCCATGGGCTCCACAGACTTCCCAGAGTTCATCAGCTTCCAGCGGCACTGCCAGC ACTGTGGGTGGCACTACTGGTAGTACTGCCAGTGGCACTTCTGGGCAGAGTACTACTGCG CCAAATTTGGTGCCTGGAGTAGGAGCTAGTATGTTCAACACACCAGGAATGCAGAGCTTG TTGCAACAAATAACTGAAAACCCACAACTTATGCAAAACATGTTGTCTGCCCCCTACATG AGAAGCATGATGCAGTCACTAAGCCAGAATCCTGACCTTGCTGCACAGATGATGCTGAAT AATCCCCTATTTGCTGGAAATCCTCAGCTTCAAGAACAAATGAGACAACAGCTCCCAACT TTCCTCCAACAAATGCAGAATCCTGATACACTATCAGCAATGTCAAACCCTAGAGCAATG CAGGCCTTGTTACAGATTCAGCAGGGTTTACAGACATTAGCAACGGAAGCCCCGGGCCTC ATCCCAGGGTTTACTCCTGGCTTGGGGGCATTAGGAAGCACTGGAGGCTCTTCGGGAACT AATGGATCTAACGCCACACCTAGTGAAAACACAAGTCCCACAGCAGGAACCACTGAACCT GGACATCAGCAGTTTATTCAGCAGATGCTTCAGGCTCTTGCTGGAGTAAATCCTCAGCTA CAGAATCCAGAAGTCAGATTTCAGCAACAACTGGAACAACTCAGTGCAATGGGATTTTTG AACCGTGAAGCAAACTTGCAAGCTCTAATAGCAACAGGAGGTGATATCAATGCAGCTATT GAAAGGTTACTGGGCTCCCAGCCATCATAG Clone variation with respect to NM_013438.4 725 c=>t;1170 g=>t;1590 g=>t >OriGene 5' read for NM_013438 unedited
AAACCAATTCCCACGAGGCCTCGTGCCGTATTCGGCACGAGGGTCGGTGTGAGCGAGCGG CGCCTGAACACACGGCGGCTGCCGAGCGCCTGACCCGGGCCTGCGCCAGAGCCTGCACCG AGCTCCGGGGCCCCACACCCGCTACCGTGGCCCTGCGCCCGTTGCTACTGAGGCTTCNGT CNCTGCATTCTTCGCTGTCCAGGCCTGCCGGCTCTGGTGTCTGCTGGCTCCTCCTTGCTC GCCTGCTCCCTCCTGCTTGCCTGATTCACCGCCGCCGCCGCCGCCACAGCCATGGCCGAG AGTGGTGAAAGCGGCGGTCCTCCGGGCTCCCAGGATAGCGCCGCCGGAGCCGAAGGTGCT GGCGCCCCCGCGGCCGCTGCCTCCGCGGAGCCCAAAATCATGAAAGTCACCGTGAAGACC CCGAAGGAAAAGGAGGAATTCGCCGTGCCCGAGAATAGCTCCGTCCAGCAGTTTAAGGAA GAAATCTCTAAACGTTTTAAATCACATACTGACCAACTTGTGTTGATATTTGCTGGAAAA ATTTTGAAAGATCAAGATACCTTGAGTCAGCATGGAATTCATGATGGACTTACTGTTCAC CTTGTCATTAAAACACAAAACAGGCCTCAGGATCATTCAGCTCAGCAAACAAATACAGCT GGAAGCAATGTTACTACATTCATCACTCCCTATAGTAACTCTACATCTGGTTCTGCTACT AACAACCCTTTTGGGTTAAGTGGCCCTGGGGGGACTTGCAGGTCTGAATAACCTTGGGGT TGAATACTACCCACTTCTTTGAACTACCGAATCAGATGCCGCGACACCTTTTGCCTAACC TGAAAGATGGTCCCATCATGGAAAACCCTTTTGTTCAAACATGCCCTCAAA >OriGene 3' read for NM_013438 unedited
GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAACATTTCAATTAC AAATTTTAATGCCTGTTAAACTACCTATGGGAGAAGCTGAGAAGTCCTAGGCAAATGCAC TTTGGGGTATACTACAGTGTTCCTTCAGTCTGCACAAAGATTAAGGTAATTTACAGTCAA TCTGTGAATGAATGTTGAGACAATGTTACATTATGTGTCTGTACAATTAATTGTCCTTAA AGAGATAACCAGAATCAGCTTTTCTACTGTATTTTCAACAAACCTGACTAACCGGCACTT TTGCTGGGAGATGTTTGTCAAAGATGCTGTAAGATTCTATACAATTAGGAAATACTCAGC TTTAAGAGTATTTTCTTATCTTCACTTTTTTAGTTACAGGTGTTTTGCTCAGAGAGCCTA TTGCAGTATGTTTCCAGAAATGCAGTCCCAAATGTGCATACTCTATATTGTATACAAATA AAACAAAATTATCAGTAGTATAAATCTTACAGCATTGTTTGCAAAAATGCATGCCAAAGT CACAATAAGCAATACTGTACCACAAATTATAGAGTGCAAATGATTTGCTTCTTTTTAATG CTTTTATTCTACATAAATTACTACCATAGGCTAATGTTTAAAAAGCAAATAAACTGGACA GATGCAGGACAAAATCTGGTCACCCAACTATAAAAGGTGATGTTTTTAAAAAATTACAAT AAATGCAGAAGTGATGCATGCAGTAGCCTTAATTCCCACTNGTCCAGAAAAGAAAATACA GAAAAACCACACATCTTACTGTACTNCACCTTTAAATGCATCATATNNTGGTTTGTTATT ACAGCACAGAATTCCCAGAGTCAAAATGAAATANAGCAGGTATTTTAAAGTTNAANGACC NNGTATCAAAATAAATTACATNTTTTCAAGATACAGAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_013438 |
| Insert Size | 2840 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_013438.3, NP_038466.2 |
| RefSeq Size | 3952 bp |
| RefSeq ORF | 1770 bp |
| Locus ID | 29979 |
| UniProt ID | Q9UMX0 |
| Domains | UBA, UBQ, STI1 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The TREX1 C-terminal Region Controls Cellular Localization through Ubiquitination *
,null,
The Journal of Biological Chemistry
,PubMed ID 23979357
[UBQLN1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206897 | UBQLN1 (Myc-DDK-tagged)-Human ubiquilin 1 (UBQLN1), transcript variant 1 |
CNY 3,990.00 |
|
| RC206897L1 | Lenti ORF clone of Human ubiquilin 1 (UBQLN1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206897L2 | Lenti ORF clone of Human ubiquilin 1 (UBQLN1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC206897L3 | Lenti ORF clone of Human ubiquilin 1 (UBQLN1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206897L4 | Lenti ORF clone of Human ubiquilin 1 (UBQLN1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG206897 | UBQLN1 (tGFP-tagged) - Human ubiquilin 1 (UBQLN1), transcript variant 1 |
CNY 4,370.00 |
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