United States
Germany
Japan
United Kingdom
China
BACE2 (NM_012105) Human Untagged Clone
CAT＃: SC110343
BACE2 (untagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_012105, the custom clone sequence may differ by one or more nucleotides
ATGGGCGCACTGGCCCGGGCGCTGCTGCTGCCTCTGCTGGCCCAGTGGCTCCTGCGCGCCGCCCCGGAGC TGGCCCCCGCGCCCTTCACGCTGCCCCTCCGGGTGGCCGCGGCCACGAACCGCGTAGTTGCGCCCACCCC GGGACCCGGGACCCCTGCCGAGCGCCACGCCGACGGCTTGGCGCTCGCCCTGGAGCCTGCCCTGGCGTCC CCCGCGGGCGCCGCCAACTTCTTGGCCATGGTAGACAACCTGCAGGGGGACTCTGGCCGCGGCTACTACC TGGAGATGCTGATCGGGACCCCCCCGCAGAAGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGC CGTGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCC AAGGGCTTTGACGTCACAGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCA CCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCACTATTTTTGAATCAGAGAATTTCTT TTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCATCAAGTTCT CTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTG GAGCCGGCTTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAG TTTGTATAAAGGAGACATCTGGTATACCCCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAA TTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAAGGCCATCGTGGACA GTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATC TCTGATTCCAGAATTCTCTGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACA CCTTGGTCTTACTTCCCTAAAATCTCCATCTACCTGAGAGACGAGAACTCCAGCAGGTCATTCCGTATCA CAATCCTGCCTCAGCTTTACATTCAGCCCATGATGGGGGCCGGCCTGAATTATGAATGTTACCGATTCGG CATTTCCCCATCCACAAATGCGCTGGTGATCGGTGCCACGGTGATGGAGGGCTTCTACGTCATCTTCGAC AGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATTGCAGGTGCTGCAGTGTCTGAAA TTTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCAT TTTGTGGATTGTGTCCTATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTG CTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATGATGAGTCCTCTCTGGTCA GACATCGCTGGAAATGA >OriGene 5' read for NM_012105 unedited
CCTCGTTTTGTAAACGACTTCATATAGGCGGCCGACGAATTCGCACGAGGTCCTCCCCGC CGCCGCCGGTCCCGGTGCGCGCCCATCCCTGCCCGCAGCCCCGCGCGCCGGCCGAGTCGC TGAGCCGCGGCTGCCGGACGGGACGGGACCGGCTAGGCTGGGCGCGCCCCCCGGGCCCCG CCGTGGGCATGGGCGCACTGGCCCGGGCGCTGCTGCTGCCTCTGCTGGCCCAGTGGCTCC TGCGCGCCGCCCCGGAGCTGGCCCCCGCGCCCTTCACGCTGCCCCTCCGGGTGGCCGCGG CCACGAACCGCGTAGTTGCGCCCACCCCGGGACCCGGGACCCCTGCCGAGCGCCACGCCG ACGGCTTGGCGCTCGCCCTGGAGCCTGCCCTGGCGTCCCCCGCGGGCGCCGCCAACTTCT TGGCCATGGTAGACAACCTGCAGGGGGACTCTGGCCGCGGCTACTACCTGGAGATGCTGA TCGGGACCCCCCCGCAGAAGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCG TGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACAT ACCGCTCCAAGGGCTTTGACGTCACAGTGAAGTACACACAAGGAAGCTGGACGGGCTTCG TTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTG CCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGNANNTACT GCCTAGCTTATGCCACACTTGCCAAGCCATCAAGTTCTCTGGAGAACCTCTTCGACTCCC TGGTGACACAAGCAAACATCCCCCACGTTTCCTCATGCANATGTGTGGAGCCCGCTTGCC CCGTGCTGGATCTGGGACCACCGGAGTAG >OriGene 3' read for NM_012105 unedited
NNNNNNTTTTGGGGGGGTTTTGGAAGCTTGGAAATCAACATCAAAATACAGTGAATCTAG AAGCATCTGGGAGCAGAACAGAGATTGAAGACGGGTGGGCACAGGTAGAAAGCGCCACCA TCGATCCCGGCTGCTGCCCTGGAAATGTGATTTTCTTAATAGCTGAGTTCATGGTTGCTT GAGGTCAGGCCTGGCTATTCATTTCCAGCGATGTCTGACCAGAGAGGACTCATCATTGAC GACCTCAGGGTCACGGGGGCGACGCTGACACCGGAACGGCAGCAGCAGCAGGACGATTAA GACAAGGAGGATGGCTCCACAGACGCTCATGAGCGCATAGGACACAATCCACAAAATGGG CTCGCTCAAAGACTGAGCGGGGACACAGTTGCTGGCTACATCCTCTGTTGAGAAAGGCCC GGAAATTTCAGACACTGCAGCACCTGCAATTTCTGCACAGGGGCTCGCTGCGAAGCCCAC CCTCTTCTGGGCTCTGTCGAAGATGACGTAGAAGCCCTCCATCACCGTGGCACCGATCAC CAGCGCATTTGTGGATGGGGAAATGCCGAATCGGTAACATTCATAATTCAGGCCGGCCCC CATCATGGGCTGAATGTAAAGCTGAGGCAGGATTGTGATACGGAATGACCTGCTGGAGTT CTCGTCTCTCAGGTAGATGGAGATTTTAGGGAAGTAAGACCAAGGTGTTTCCGAATTCGT CCAGCACGCCAGCTGGGACCCAGTCCAGANACCATCAGAGAATTCTGGAATCAGAGATGC GCGGGCCACAGCTTCCACCACCGCATCAAACACCTTCTGGGGCATGCGCAGCAGCGTGGT GCCACTGTACACGATGGCCTTGTCTGCGTTATACTCTCTGCAGTCCAGATAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_012105 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_012105.3, NP_036237.2 |
| RefSeq Size | 2993 bp |
| RefSeq ORF | 1557 bp |
| Locus ID | 25825 |
| UniProt ID | Q9Y5Z0 |
| Domains | asp |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Protein Pathways | Alzheimer's disease |
| Gene Summary | This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (a) represents the longest transcript and encodes the longest isoform (A). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204860 | BACE2 (Myc-DDK-tagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a |
CNY 3,856.00 |
|
| RC204860L1 | Lenti ORF clone of Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, Myc-DDK-tagged |
CNY 6,256.00 |
|
| RC204860L2 | Lenti ORF clone of Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mGFP tagged |
CNY 5,890.00 |
|
| RC204860L3 | Lenti ORF clone of Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204860L4 | Lenti ORF clone of Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mGFP tagged |
CNY 6,256.00 |
|
| RG204860 | BACE2 (tGFP-tagged) - Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a |
CNY 5,456.00 |
|
| SC320428 | BACE2 (untagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a |
CNY 3,864.00 |
