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IRAG1 (NM_130385) Human Untagged Clone
CAT＃: SC110146
MRVI1 (untagged)-Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 2
CNY 5,888.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IRAG; JAW1L; MRVI1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_130385, the custom clone sequence may differ by one or more nucleotides
ATGGTAAAAGCTCCCCAGAGTGAAGAGAGGCTGGCCAGAGGAGGAAAGGAGAATAACTCAGTTTTAGCCT GTGGAGCCCAGGCCTCTTGGAGCATCTTTGGGGCTGACGCAGCGGAGGTTCCGGGCACACGTGGCCACTC CCAGCAGGAGGCTGCCATGCCCCACATTCCCGAGGACGAGGAGCCCCCCGGAGAGCCACAGGCAGCCCAG AGCCCTGCCGGCCAAGGTCCTCCTGCCGCAGGAGTATCTTGCAGTCCAACTCCCACGATTGTCCTGACTG GGGATGCCACTTCACCAGAAGGAGAAACCGACAAAAACCTGGCCAACAGAGTTCACAGTCCCCACAAGAG GCTTTCTCACCGACACTTGAAGGTGTCCACTGCCTCCCTGACATCTGTGGACCCCGCGGGGCACATCATT GACCTGGTGAATGACCAGCTGCCAGACATCAGCATCTCAGAGGAGGACAAGAAGAAAAACCTGGCGCTGC TGGAAGAAGCCAAGTTGGTGAGTGAGCGATTCCTGACCCGCCGTGGGAGGAAGTCCAGGAGCAGCCCCGG AGACTCCCCATCAGCTGTTTCCCCGAACCTCAGCCCCAGCGCTTCTCCTACATCCTCTCGGAGCAACTCA CTTACAGTCCCCACCCCGCCAGGTTTGGATGTGTGCAGTGGCCCGCCATCCCCTCTGCCTGGAGCACCAC CACAGAAGGGGGATGAGGCCGACGTCTCTTCACCTCACCCTGGCGAGCCTAACGTCCCCAAAGGGCTAGC TGACAGGAAGCAGAATGACCAGAGGAAAGTGTCTCAGGGCAGGCTGGCTCCTCGTCCTCCTCCAGTTGAG AAGTCCAAAGAGATTGCAATAGAACAAAAGGAAAACTTCGATCCCCTCCAGTACCCCGAGACCACACCCA AAGGCCTAGCTCCTGTTACAAACAGCAGTGGGAAAATGGCCCTGAACAGCCCTCAGCCTGGCCCCGTGGA GAGCGAGCTGGGGAAGCAGCTCTTGAAAACGGGCTGGGAGGGCAGCCCTCTGCCGAGAAGTCCAACCCAG GATGCGGCAGGAGTGGGTCCCCCAGCCTCCCAGGGGAGAGGCCCAGCTGGAGAGCCGATGGGGCCCGAGG CTGGCTCCAAAGCTGAGCTTCCACCCACTGTGTCCCGGCCCCCGCTGCTGCGAGGGCTCTCCTGGGACAG TGGCCCTGAAGAACCTGGCCCCCGGCTGCAGAAAGTGCTTGCCAAGCTGCCACTGGCAGAGGAAGAAAAG CGTTTTGCAGGCAAGGCCGGCGGCAAGCTGGCCAAGGCCCCTGGTCTCAAAGACTTTCAGATACAAGTGC AGCCCGTGCGGATGCAGAAACTGACCAAGCTCCGAGAGGAGCACATCCTGATGAGAAATCAGAACTTAGT GGGGCTCAAGCTTCCAGACCTTAGTGAAGCAGCTGAGCAGGAAAAAGGGCTTCCTTCTGAACTCTCCCCA GCTATTGAGGAAGAAGAGTCAAAGAGTGGCTTAGATGTCATGCCTAATATTTCTGATGTGCTGCTGCGCA AACTGCGGGTCCACAGGAGTCTCCCTGGAAGTGCCCCTCCACTCACTGAAAAGGAAGTTGAGAACGTGTT TGTGCAACTGTCCTTGGCCTTTAGAAATGACAGCTACACTCTGGAATCTAGAATTAACCAGGCTGAAAGG GAACGCAACCTGACAGAGGAGAACACTGAGAAAGAACTGGAAAACTTCAAAGCTTCCATTACGTCCTCAG CTTCACTCTGGCACCACTGTGAGCACCGGGAAACCTACCAGAAGTTGCTGGAGGACATCGCTGTCCTGCA CCGCCTGGCTGCCCGCCTCTCCAGCCGAGCTGAGGTGGTAGGCGCCGTCCGCCAGGAAAAGCGCATGTCG AAAGCAACGGAAGTGATGATGCAGTATGTGGAGAATCTAAAGAGGACGTATGAGAAGGACCATGCGGAGC TCATGGAGTTTAAAAAGCTTGCAAATCAGAATTCAAGCCGCAGCTGTGGCCCCTCTGAAGATGGGGTCCC TCGCACGGCACGGTCCATGTCCCTCACGCTGGGAAAGAATATGCCTCGCCGGAGGGTCAGCGTTGCTGTG GTTCCTAAGTTTAATGCCCTGAATCTGCCTGGCCAAACTCCCAGCTCATCATCCATTCCCTCCTTACCAG CCTTGTCGGAATCACCCAATGGGAAAGGCAGCCTACCTGTCACTTCAGCACTGCCTGCACTTTTGGAAAA TGGAAAGACAAATGGGGACCCAGATTGTGAAGCCTCTGCTCCTGCGCTGACCCTGAGCTGCCTGGAGGAG CTTAGTCAGGAGACCAAGGCCAGGATGGAGGAAGAAGCCTACAGCAAGGGATTCCAAGAAGGTCTAAAGA AGACCAAAGAACTTCAAGACCTGAAGGAGGAGGAGGAAGAACAGAAGAGTGAGAGTCCTGAGGAACCTGA AGAGGTAGAAGAAACTGAGGAAGAGGAAAAGGGCCCAAGAAGCAGCAAACTTGAAGAATTGGTCCATTTC TTACAAGTCATGTATCCCAAACTGTGTCAGCACTGGCAAGTGATCTGGATGATGGCTGCAGTGATGCTGG TCTTGACTGTTGTGCTGGGGCTCTACAATTCCTATAACTCTTGTGCAGAGCAGGCTGATGGGCCCCTTGG AAGATCCACTTGCTCGGCAGCCCAGAGGGACTCCTGGTGGAGCTCAGGACTCCAGCATGAGCAGCCTACA GAGCAGTAG >OriGene 5' read for NM_130385 unedited
CCCACCTCCCGGGTTCAAGCAATTCTCATGCCTCAGCCTCCCAAGTAGCTGGGATTACAG GGTCCTCCTACCGCAGGAGTATCTTGCAGTCCAACTCCCACGATTGTCCTGACTGGGGAT GCCACTTCACCAGAAGGAGAAACCGACAAAAACCTGGCCAACAGAGTTCACAGTCCCCAC AAGAGGCTTTCTCACCGACACTTGAAGGTGTCCACTGCCTCCCTGACATCTGTGGACCCC GCGGGGCACATCATTGACCTGGTGAATGACCAGCTGCCAGACATCAGCATCTCAGAGGAG GACAAGAAGAAAAACCTGGCGCTGCTGGAAGAAGCCAAGTTGGTGAGTGAGCGATTCCTG ACCCGCCGTGGGAGGAAGTCCAGGAGCAGCCCCGGAGACTCCCCATCAGCTGTTTCCCCG AACCTCAGCCCCAGCGCTTCTCCTACATCCTCTCGGAGCAACTCACTTACAGTCCCCACC CCGCCAGGTTTGGATGTGTGCAGTGGCCCGCCATCCCCTCTGCCTGGAGCACCACCACAG AAGGGGGATGAGGCCGACGTCTCTTCACCTCACCCTGGCGAGCCTAACGTCCCCAAAGGG CTAGCTGACAGGAAGCAGAATGACCAGAGGAAAGTGTCTCAGGGCAGGCTGGGCTCTCGT CCTCCTCCATTGAGAAGTCCNAGAGATGGCATAGAACAAAGGAAAACTCGATCCCTTCAG TACCCGAGACACCCCAAAGGCTAACTCTGTTCAAACACAGTGGAAAATGCCCTGAACACC TCAACTGGCCCGGGAGAGCAA >OriGene 3' read for NM_130385 unedited
NTACGTATAGCTATGNACCGCGCCGCAATCTATGATCGGTTTTTTTTTTTTTTTTTTGAG AAGCCTTTCCTACTTCTGTAAAAAGAAACTCTCATTCCAAAGGAAAGAATGGGAGGCTGA AGTTATTGAAAATGAGATGGGAAATGGGAAGATAGTCACTTTGCAACTCCAAATTCCAGG TCTGATGCTTAAGGTGTTAGTCATTAAGCAAATTCTTCCTGATAACCAATTACAGAGAGG AAAAAAGAGAGTAAGTTTTTTACTGCCCCCTACCTCCTCCTCCCCCGTGCCCCGCTCCTT ACCCCCAACCACCAGTGAAGGTGTTTTAGTTCTCCCCAGCCACCTGAGCTAGGGGCAGGA GACCTTCCCTTCCAATAGAGTTCCTTGGTGAAGGTGACTTCTTCATCCACTGGATGCTTT CCCAGGGCAGTTTTGTTGATCCTCCAAGAACATCAAGTCACTGTGTATGAATAGCTCCCA CAGAAGTGCCGAGTGTTAAAAGAACCCTTCCTCATGACCTGATGGGATGGGCGGCAGTGT GTCCACACTTGGGCCTGACGTTATACTTGGGGAAAGGGTGGTAGTCTGAGTGTCTCANAG CAAGGCACTGGCTAGGTGTGAGGTTTCCTACTGCTCTGTAAGCTGCTCATGCTGGAGTCC TGAGCTCCACCAGGAGTCCCTCTGGGCTGCCGAGCAAGTGGATCTTCCAAGGGGCCCATC AGCCTGCTCTGCACAAGAGGTATAGGAATTGTAGAGCCCCAGCACAACAGTCAAGACCAG CATCACTGCAGCCATCATCCAGATCACTTGCCAGTGCTGACACAGTTTGGGATACATGAC TTGTAAGAAATGGACCAATTCTTN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_130385 |
| Insert Size | 3750 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_130385.1, NP_569056.2 |
| RefSeq Size | 6376 bp |
| RefSeq ORF | 2412 bp |
| Locus ID | 10335 |
| UniProt ID | Q9Y6F6 |
| Protein Families | Transmembrane |
| Protein Pathways | Vascular smooth muscle contraction |
| Gene Summary | This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used. [provided by RefSeq, May 2011] Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (d) has a distinct N-terminus and is longer than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215536 | MRVI1 (Myc-DDK-tagged)-Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 2 |
CNY 7,130.00 |
|
| RC215536L3 | Lenti-ORF clone of MRVI1 (Myc-DDK-tagged)-Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 2 |
CNY 9,030.00 |
|
| RC215536L4 | Lenti-ORF clone of MRVI1 (mGFP-tagged)-Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 2 |
CNY 9,030.00 |
|
| RG215536 | MRVI1 (tGFP-tagged) - Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 2 |
CNY 7,890.00 |
|
| SC318300 | MRVI1 (untagged)-Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 2 |
CNY 7,220.00 |
