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Apolipoprotein L 1 (APOL1) (NM_003661) Human Untagged Clone
CAT＃: SC109941
APOL1 (untagged)-Human apolipoprotein L, 1 (APOL1), transcript variant 1
CNY 3,656.00
CNY 7,220.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APO-L; APOL; APOL-I; FSGS4 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC109941 sequence for NM_003661 edited (data generated by NextGen Sequencing)
ATGGAGGGAGCTGCTTTGCTGAGAGTCTCTGTCCTCTGCATCTGGATGAGTGCACTTTTC CTTGGTGTGGGAGTGAGGGCAGAGGAAGCTGGAGCGAGGGTGCAACAAAACGTTCCAAGT GGGACAGATACTGGAGATCCTCAAAGTAAGCCCCTCGGTGACTGGGCTGCTGGCACCATG GACCCAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAGTGAGC ACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCT GCTGAACTGCCCAGGAATGAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGA CAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACTGGTTT CTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCC CTTGCAGATGGGGTTCAGAAGGTCCACAAAGGCACCACCATCGCCAATGTGGTGTCTGGC TCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCTTCACA GAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTG ACCGGGATTACCAGCAGTACCATGGACTACGGAAAGAAGTGGTGGACACAAGCCCAAGCC CACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAAGGAGTTTTTGGGTGAG AACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGG AAGGACATCCGTGCCCTCAGACGAGCCAGAGCCAATCTTCAGTCAGTACCGCATGCCTCA GCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTGGAGAGA GTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCT GTAAGCTTCTTTCTTGTGCTGGATGTAGTCTACCTCGTGTACGAATCAAAGCACTTACAT GAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAGGTGGCTCAGGAGCTGGAGGAG AAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGA Clone variation with respect to NM_003661.3 764 g=>a;960 g=>a >OriGene 5' read for NM_003661 unedited
TACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTCAGAACAGCTGGATCTTGC TCAGTCTCTGCCAGGGGAAGATTCCTTGGAGGAGGCCCTGCAGCGACATGGAGGGAGCTG CTTTGCTGAGAGTCTCTGTCCTCTGCATCTGGATGAGTGCACTTTTCCTTGGTGTGGGAG TGAGGGCAGAGGAAGCTGGAGCGAGGGTGCAACAAAACGTTCCAAGTGGGACAGATACTG GAGATCCTCAAAGTAAGCCCCTCGGTGACTGGGCTGCTGGCACCATGGACCCAGAGAGCA GTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAGTGAGCACACAGAATCTGC TACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCCA GGAATGAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGA AAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACTGGTTTCTGAAAGAGTTTC CTCGGTTGAAAAGTAAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGATGGGG TTCAGAAGGTCCACAAAGGCACCACCATCGCCAATGTGGNTGTCTGGCTCTCTCAGCATT TCCTCTGGCATCCTGACCCTCGTCGGCATGGGTTTGGCACCCTTCACAGAGGGAGGCAGC CTTGTACTCTTGGAACCTGNGNNATGGAGTGGNAATCACAGCAGCTTTGACCGGGGATAC CAGCAGTACATAGACTACGNAANGAAGTGGTGGGACACAGCCCAAGCCCACGACTGGTCA TCANAAGCTTGACANNATGANGAGTGAANGGGAGTTTTGGGTGAGACATTATCACTTTCT TTNCTAGCTGGCATACTTACACTACACGAGCATGGGAGGGACTNCTGCCTAGACAGCAAG CATTTTATCATACGATGCTAGCTACCCCCGGTC >OriGene 3' read for NM_003661 unedited
CTATGGCACGCGGCACGCAATCTAGAATCGAGTTTTTTTTTTTTTTTTTTGAGAGGAGTC TCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGATATCTCGGCTCACTGCAAGCTCCACC TCCCAGGCTCACGCCATTCTCCTGCCTCAGCCGCCCAGTCAGCCGGAACCACAGGCGCCC GCCACCATGCCCGGCCAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGCTAGC CAGGATGGCCTCGATCTCCTGACCTCGTGATCCGCCCGCCTTGGCCTCCCAAAGTGCCCG GACCACAGGCATGAGCCACTGCGCCCGGACCCCCAATATATTCTTTAGTCTAAAGCAAAC TGCTTCTTCCCATTCCCCACACTCTGCAGTTCCCATTTTTCCCTTATTGCAGGCTCAAAT GTTCCTGCCTTATACTTGCTGCACTGCCATCTGCATTAACCCCTCCCCTGCTGTGCTCAC CTATGGAAATGCCAAAGCCCCTAACACTCAGTTCCATAAACTTTACCTGACCCTCTTTAT CCCCCTAATAAAATGTTTGCATTTGGGCCAAAACCGATGGCTCACGCCTGTAATCCCACT ACTTTGGGAGGCCAAGGTGGGCATATCAACAGGCCAGGAGATCGACACCATCCTGGCGCA CACGGCCGAAACCCCATCTCTATTAAAAATTCCCAAATTACCTGGGCAGGCNGGCAACCG CCTGTTTACTCAACTACTTGGGCAGGCCAAGGCAGGAGAATCCGCTTGACATGGGAAGAC ACCCCTGTCTGGACCCAGATCGCCCCACTGCACTCCACTTTGCGAACAGACAAGACTTTG GCTCAAACAAAAAAAAATAGTTTGCTTTTGGCCTGCGCCCCGCCAGCTTATCTTTCTGGG GGTGGACTGCCCGGAGCCCACATCCGCCCCCCCTCTCAATATTTAACCCCCCATAATCTC CCCTCCATT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003661 |
| Insert Size | 2140 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003661.2, NP_003652.2 |
| RefSeq Size | 2856 bp |
| RefSeq ORF | 1197 bp |
| Locus ID | 8542 |
| UniProt ID | O14791 |
| Protein Families | Secreted Protein, Transmembrane |
| Gene Summary | This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] Transcript Variant: This variant (1) encodes the predominant protein (isoform a). Variants 1 and 3 encode the same protein (isoform a). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Domain-Specific Antibodies Reveal Differences in the Membrane Topologies of Apolipoprotein L1 in Serum and Podocytes
,Gupta, N;Wang, X;Wen, X;Moran, P;Paluch, M;Hass, PE;Heidersbach, A;Haley, B;Kirchhofer, D;Brezski, RJ;Peterson, AS;Scales, SJ;,
J. Am. Soc. Nephrol.
,PubMed ID 32764138
[APOL1]
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Blocking the 5' splice site of exon 4 by a morpholino oligomer triggers APOL1 protein isoform switch
,Cheatham, AM;Davis, SE;Khatua, AK;Popik, W;,
Sci Rep
,PubMed ID 29880816
[APOL1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211114 | APOL1 (Myc-DDK-tagged)-Human apolipoprotein L, 1 (APOL1), transcript variant 1 |
CNY 5,488.00 |
|
| RC211114L1 | Lenti ORF clone of Human apolipoprotein L, 1 (APOL1), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC211114L2 | Lenti ORF clone of Human apolipoprotein L, 1 (APOL1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC211114L3 | Lenti ORF clone of Human apolipoprotein L, 1 (APOL1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC211114L4 | Lenti ORF clone of Human apolipoprotein L, 1 (APOL1), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RG211114 | APOL1 (tGFP-tagged) - Human apolipoprotein L, 1 (APOL1), transcript variant 1 |
CNY 7,088.00 |
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