United States
Germany
Japan
United Kingdom
China
TAP2 (NM_000544) Human Untagged Clone
CAT＃: SC109816
TAP2 (untagged)-Human transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (TAP2), transcript variant 1
CNY 13,590.00
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ABC18; ABCB3; APT2; D6S217E; PSF-2; PSF2; RING11 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_000544, the custom clone sequence may differ by one or more nucleotides
ATGCGGCTCCCTGACCTGAGACCCTGGACCTCCCTGCTGCTGGTGGACGCGGCTTTACTGTGGCTGCTTC AGGGCCCTCTGGGGACTTTGCTTCCTCAAGGGCTGCCAGGACTATGGCTGGAGGGGACCCTGCGGCTGGG AGGGCTGTGGGGGCTGCTAAAGCTAAGAGGGCTGCTGGGATTTGTGGGGACACTGCTGCTCCCGCTCTGT CTGGCCACCCCCCTGACTGTCTCCCTGAGAGCCCTGGTCGCGGGGGCCTCACGTGCTCCCCCAGCCAGAG TCGCTTCAGCCCCTTGGAGCTGGCTGCTGGTGGGGTACGGGGCTGCGGGGCTCAGCTGGTCACTGTGGGC TGTTCTGAGCCCTCCTGGAGCCCAGGAGAAGGAGCAGGACCAGGTGAACAACAAAGTCTTGATGTGGAGG CTGCTGAAGCTCTCCAGGCCGGACCTGCCTCTCCTCGTTGCCGCCTTCTTCTTCCTTGTCCTTGCTGTTT TGGGTGAGACATTAATCCCTCACTATTCTGGTCGTGTGATTGACATCCTGGGAGGTGATTTTGACCCCCA TGCCTTTGCCAGTGCCATCTTCTTCATGTGCCTCTTCTCCTTTGGCAGCTCACTGTCTGCAGGCTGCCGA GGAGGCTGCTTCACCTACACCATGTCTCGAATCAACTTGCGGATCCGGGAGCAGCTTTTCTCCTCCCTGC TGCGCCAGGACCTCGGTTTCTTCCAGGAGACTAAGACAGGGGAGCTGAACTCACGGCTGAGCTCGGATAC CACCCTGATGAGTAACTGGCTTCCTTTAAATGCCAATGTGCTCTTGCGAAGCCTGGTGAAAGTGGTGGGG CTGTATGGCTTCATGCTCAGCATATCGCCTCGACTCACCCTCCTTTCTCTGCTGCACATGCCCTTCACAA TAGCAGCGGAGAAGGTGTACAACACCCGCCATCAGGAAGTGCTTCGGGAGATCCAGGATGCAGTGGCCAG GGCGGGGCAGGTGGTGCGGGAAGCCGTTGGAGGGCTGCAGACCGTTCGCAGTTTTGGGGCCGAGGAGCAT GAAGTCTGTCGCTATAAAGAGGCCCTTGAACAATGTCGGCAGCTGTATTGGCGGAGAGACCTGGAACGCG CCTTGTACCTGCTCGTAAGGAGGGTGCTGCACTTGGGGGTGCAGATGCTGATGCTGAGCTGTGGGCTGCA GCAGATGCAGGATGGGGAGCTCACCCAGGGCAGCCTGCTTTCCTTTATGATCTACCAGGAGAGCGTGGGG AGCTATGTGCAGACCCTGGTATACATATATGGGGATATGCTCAGCAACGTGGGAGCTGCAGAGAAGGTTT TCTCCTACATGGACCGACAGCCAAATCTGCCTTCACCTGGCACGCTTGCCCCCACCACTCTGCAGGGGGT TGTGAAATTCCAAGACGTCTCCTTTGCATATCCCAATCGCCCTGACAGGCCTGTGCTCAAGGGGCTGACG TTTACCCTACGTCCTGGTGAGGTGACGGCGCTGGTGGGACCCAATGGGTCTGGGAAGAGCACAGTGGCTG CCCTGCTGCAGAATCTGTACCAGCCCACAGGGGGACAGGTGCTGCTGGATGAAAAGCCCATCTCACAGTA TGAACACTGCTACCTGCACAGCCAGGTGGTTTCAGTTGGGCAGGAGCCTGTGCTGTTCTCCGGTTCTGTG AGGAACAACATTGCTTATGGGCTGCAGAGCTGCGAAGATGATAAGGTGATGGCGGCTGCCCAGGCTGCCC ACGCAGATGACTTCATCCAGGAAATGGAGCATGGAATATACACAGATGTAGGGGAGAAGGGAAGCCAGCT GGCTGCGGGACAGAAACAACGTCTGGCCATTGCCCGGGCCCTTGTACGAGACCCGCGGGTCCTCATCCTG GATGAGGCTACTAGTGCCCTAGATGTGCAGTGCGAGCAGGCCCTGCAGGACTGGAATTCCCGTGGGGATC GCACAGTGCTGGTGATTGCTCACAGGCTGCAGGCAGTTCAGCGCGCCCACCAGATCCTGGTGCTCCAGGA GGGCAAGCTGCAGAAGCTTGCCCAGCTCCAGGAGGGACAGGACCTCTATTCCCGCCTGGTTCAGCAGCGG CTGATGGACTGA >OriGene 5' read for NM_000544 unedited
CACAATTTGTATACGACTCACTATAGGCGGCCCGCGAATTCGCACGAGGCGGTAGCGAGG TTGGGAGAGACGGAGCGGACCTCAGCGCTGAAGCAGAAGCCCCCGGAGCTGCGGTCTCCC CGCCGCGGCTGAGCCATGCGGCTCCCTGACCTGAGACCCTGGACCTCCCTGCTGCTGGTG GACGCGGCTTTACTGTGGCTGCTTCAGGGCCCTCTGGGGACTTTGCTTCCTCAAGGGCTG CCAGGACTATGGCTGGAGGGGACCCTGCGGCTGGGAGGGCTGTGGGGGCTGCTAAAGCTA AGAGGGCTGCTGGGATTTGTGGGGACACTGCTGCTCCCGCTCTGTCTGGCCACCCCCCTG ACTGTCTCCCTGAGAGCCCTGGTCGCGGGGGCCTCACGTGCTCCCCCAGCCAGAGTCGCT TCAGCCCCTTGGAGCTGGCTGCTGGTGGGGTACGGGGCTGCGGGGCTCAGCTGGTCACTG TGGGCTGTTCTGAGCCCTCCTGGAGCCCAGGAGAAGGAGCAGGACCAGGTGAACAACAAA GTCTTGATGTGGAGGCTGCTGAAGCTCTCCAGGCCGGACCTGCCTCTCCTCGTTGCCGCC TTCTTCTTCCTTGTCCTTGCTGTTTTGGGTGAGACATTAATCCCTCACTATTCTGGTCGT GTGATTGACATCCTGNGAGGTGATTTTGACCCCCATGCCTTTGCCAGTGCCATCTTCTTC ATGTGCCCTCTCTCCTTTGGCAGCTCACTGTCTGCANGCTGCCCGAGAGGCTGCTTCACC TACACCATGTCTCGAATCAACTTGCNGATCCGGGAGCAGCTTTTCTCCTCCCTGCTGCGC CCAGACCCCTCGGTTCTTCCCAGNAGACTAAGACAAGGGGAGCTGAACTCACGCCTGACC TCCGATACCAACCTGATGAAGTAACTGGCTTCCTTTA >OriGene 3' read for NM_000544 unedited
ACCGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTATTTTAAAATATATGTA TTATGCCACAAAATACTCCTCATCACCAGGCAAAGCTCTAGTCACCAGGGAATTAAGTTT CCTGGACACAGACAGCCCCCACCCCACCCCACCCCACCTTTCCACCCCACCAAAAGCACA CAGTGTCCAAATCTCCATCATGCCTGCAACTCAGGAACAGCTATCTGGCCGCACAGCTCT AGGGAAACTCAAAGCAGGAACAGCTCTGGGTCCTGGAGACGCCCCTGAGAAGAGGGCCCA GTATCCCTGGGGCCTCAGTCCATCAGCCGCTGCTGCACCAGGCGGGAATAAAGGTCCTGT CCCTCCTAGAGCTGGGCAAGCTTTCTGCAGCTTGCCCTCCTGGAACACCCAGGATCTGGT GGGCGCGCTGAACTGTCTGCAGCCTGTGAGCAATCACCACCACTGTGCGATCCCCACGGG AATTCCATTCCTGCAGGGCCTGCTTTCACTTGCCATTTAGGCACTAGTTCCCCTCTCTCA CTATGATGACCCTTCGGTTTCTCCATGGCCCGCGCCTTGTCCATACTTTGTTTTTGTCCC GGCAATACATTGGCTCCCCTTCTCCCGACCTCTGGGGTATTCCCATGCCCCCATTCCCGC ATGAAAAATCGGCGTGGACATCTGGCCAGCGCCTCACCTTTTATTCCTGTAATCTTCCTA CCCATAACATCGTTTTTTCTACAATAACTCGTTATAATATATGTTTTTGCCAACTTAAAC CCTCGGTTCTGCGCTTCCACGCTATTCCCGTNCATGGCTCTTGCCCCTCTCCCCTCGTCC TCTTTGTCCTCTCATCTCCTCCCACAGCTACCCTTTGTTTTCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000544 |
| Insert Size | 2380 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000544.3, NP_000535.3 |
| RefSeq Size | 5679 bp |
| RefSeq ORF | 2112 bp |
| Locus ID | 6891 |
| UniProt ID | Q03519 |
| Domains | ABC_membrane, ABC_tran, AAA |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ABC transporters, Antigen processing and presentation, Primary immunodeficiency |
| Gene Summary | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014] Transcript Variant: This variant (1, B allele) represents the longer transcript and encodes the longest isoform (1). An allele (variant 1, A allele) exists in which a single nt change creates an internal stop codon, leading to a protein that is 17 aa shorter at the C-terminus. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222611 | TAP2 (Myc-DDK-tagged)-Human transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (TAP2), transcript variant 1 |
CNY 7,030.00 |
|
| RC222611L3 | Lenti-ORF clone of TAP2 (Myc-DDK-tagged)-Human transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (TAP2), transcript variant 1 |
CNY 8,930.00 |
|
| RC222611L4 | Lenti-ORF clone of TAP2 (mGFP-tagged)-Human transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (TAP2), transcript variant 1 |
CNY 8,930.00 |
|
| RG222611 | TAP2 (tGFP-tagged) - Human transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (TAP2), transcript variant 1 |
CNY 7,700.00 |
