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PTP epsilon (PTPRE) (NM_130435) Human Untagged Clone
CAT＃: SC109677
PTPRE (untagged)-Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 2
CNY 4,784.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HPTPE; PTPE; R-PTP-EPSILON |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC109677 sequence for NM_130435 edited (data generated by NextGen Sequencing)
ATGAGCAACAGGAGTAGCTTTTCCCGGCTCACCTGGTTCAGGAAGCAGAGGAAAGCTGTG GTCAGCACCAGCGACAAGAAGATGCCCAACGGAATCTTGGAGGAGCAAGAGCAGCAAAGG GTGATGCTGCTCAGCAGGTCACCCTCAGGGCCCAAGAAGTATTTTCCCATCCCCGTGGAG CACCTGGAGGAGGAGATCCGTATCAGATCCGCCGACGACTGCAAGCAGTTTCGGGAGGAG TTCAACTCATTGCCATCTGGACACATACAAGGAACTTTTGAACTGGCAAATAAAGAAGAA AACAGAGAAAAAAACAGATATCCCAACATCCTTCCCAATGACCATTCTAGGGTGATTCTG AGCCAACTGGATGGAATTCCCTGTTCAGACTACATCAATGCTTCCTACATAGATGGTTAC AAAGAGAAGAATAAATTCATAGCAGCTCAAGGTCCCAAACAGGAAACGGTTAACGACTTC TGGAGAATGGTCTGGGAGCAAAAGTCTGCGACCATCGTCATGTTAACAAACTTGAAAGAA AGGAAAGAGGAAAAGTGCCATCAGTACTGGCCCGACCAAGGCTGCTGGACCTATGGAAAC ATCCGGGTGTGCGTGGAGGACTGCGTGGTTTTGGTCGACTACACCATCCGGAAGTTCTGC ATACAGCCACAGCTCCCCGACGGCTGCAAAGCCCCCAGGCTGGTCTCACAGCTGCACTTC ACCAGCTGGCCCGACTTCGGAGTGCCTTTTACCCCCATTGGGATGCTGAAGTTCCTCAAG AAAGTAAAGACGCTCAACCCCGTGCACGCTGGGCCCATCGTGGTCCACTGTAGCGCGGGC GTGGGCCGGACGGGCACCTTCATTGTGATCGATGCCATGATGGCCATGATGCACGCGGAG CAGAAGGTGGATGTGTTTGAATTTGTGTCTCGAATCCGTAATCAGCGCCCTCAGATGGTT CAAACGGATATGCAGTACACGTTCATCTACCAAGCCTTACTCGAGTACTACCTCTACGGG GACACAGAGCTGGACGTGTCCTCCCTGGAGAAGCACCTGCAGACCATGCACGGCACCACC ACCCACTTCGACAAGATCGGGCTGGAGGAGGAGTTCAGGAAATTGACAAATGTCCGGATC ATGAAGGAGAACATGAGGACGGGCAACTTGCCGGCAAACATGAAGAAGGCCAGGGTCATC CAGATCATCCCGTATGACTTCAACCGAGTGATCCTTTCCATGAAAAGGGGTCAAGAATAC ACAGACTACATCAACGCATCCTTCATAGACGGCTACCGACAGAAGGACTATTTCATCGCC ACCCAGGGGCCACTGGCACACACGGTTGAGGACTTCTGGAGGATGATCTGGGAATGGAAA TCCCACACTATCGTGATGCTGACGGAGGTGCAGGAGAGAGAGCAGGATAAATGCTACCAG TATTGGCCAACCGAGGGCTCAGTTACTCATGGAGAAATAACGATTGAGATAAAGAATGAT ACCCTTTCAGAAGCCATCAGTATACGAGACTTTCTGGTCACTCTCAATCAGCCCCAGGCC CGCCAGGAGGAGCAGGTCCGAGTAGTGCGCCAGTTTCACTTCCACGGCTGGCCTGAGATC GGGATTCCCGCCGAGGGCAAAGGCATGATTGACCTCATCGCAGCCGTGCAGAAGCAGCAG CAGCAGACAGGCAACCACCCCATCACCGTGCACTGCAGTGCCGGAGCTGGGCGAACAGGT ACATTCATAGCCCTCAGCAACATTTTGGAGCGAGTAAAAGCCGAGGGACTTTTAGATGTA TTTCAAGCTGTGAAGAGTTTACGACTTCAGAGACCACATATGGTGCAAACCCTGGAACAG TATGAATTCTGCTACAAAGTGGTACAAGATTTTATTGATATATTTTCTGATTATGCTAAT TTCAAATGA Clone variation with respect to NM_130435.3 >OriGene 5' read for NM_130435 unedited
CGTTCACATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACCAGGTGGCTCAGC CATGAGCAACAGGAGTAGCTTTTCCCGGCTCACCTGGTTCAGGAAGCAGAGGAAAGCTGT GGTCAGCACCAGCGACAAGAAGATGCCCAACGGAATCTTGGAGGAGCAAGAGCAGCAAAG GGTGATGCTGCTCAGCAGGTCACCCTCAGGGCCCAAGAAGTATTTTCCCATCCCCGTGGA GCACCTGGAGGAGGAGATCCGTATCAGATCCGCCGACGACTGCAAGCAGTTTCGGGAGGA GTTCAACTCATTGCCATCTGGACACATACAAGGAACTTTTGAACTGGCAAATAAAGAAGA AAACAGAGAAAAAAACAGATATCCCAACATCCTTCCCAATGACCATTCTAGGGTGATTCT GAGCCAACTGGATGGAATTCCCTGTTCAGACTACATCAATGCTTCCTACATAGATGGTTA CAAAGAGAAGAATAAATTCATAGCAGCTCAAGGTCCCAAACAGGAAACGGTTAACGACTT CTGGAGAATGGTCTGGGAGCAAAAGTCTGCGACCATCGTCATGTTAACAAACTTGAAAGA AAGGAAAGAGGAAAAGTGCCATCAGTACTGGCCCGACCAAGGCTGCTGGACCTATGGAAA CATCCGGGTGTGCGTGGAGGACTGCGTGGTTNTGGTCGACTACACCATCCGGAAGTTCTG CATACAGCCACAGCTCCCCGACGGCTGCANAGCCCCCAGGCTGGTCTCACAGCTGCACTT CACCAGCTGGCCCGACTTCGNAGTGCCTTTTACCCCCATTGGGATGCTGAAGTTCCCTCA GAAAGTAAGACGCTCAACCCGTGCACGCTGGGCCCATCGTGGTCCACTGNTACGCGGGCG TGGGCCGGNACGGCACCTCCATGTGATCGATCCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_130435 |
| Insert Size | 2200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_130435.2, NP_569119.1 |
| RefSeq Size | 5002 bp |
| RefSeq ORF | 1929 bp |
| Locus ID | 5791 |
| UniProt ID | P23469 |
| Domains | Y_phosphatase, PTPc_motif |
| Protein Families | Druggable Genome, Phosphatase, Transmembrane |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq, Oct 2015] Transcript Variant: This variant (2) contains an alternate exon in place of the first 5 exons compared to variant 3. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 3. The encoded protein is a cytoplasmic isoform of this PTP. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217899 | PTPRE (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 2 |
CNY 4,784.00 |
|
| RC217899L3 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC217899L4 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG217899 | PTPRE (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 2 |
CNY 6,384.00 |
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