MEK5 (MAP2K5) (NM_145160) Human Untagged Clone
CAT#: SC109631
MAP2K5 (untagged)-Human mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 1
CNY 3,656.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | HsT17454; MAPKK5; MEK5; PRKMK5 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_145160 edited
ATGTGAGCCTCTTTAACCTGTAATGCTGTGGCTAGCCCTTGGCCCCTTTCCTGCCATGGA GAACCAGGTGCTGGTAATTCGCATCAAGATCCCAAATAGTGGGCGCGGTGGACTGGACAG TGCACTCCGGGCCGCAGTTACTCTTCAGGGATGTGCTGGATGTGATAGGCCAGGTTCTGC CTGAAGCAACAACTACAGCATTTGAATATGAAGATGAAGATGGTGATCGAATTACAGTGA GAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAACAGC AAGTAAATGGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTG GGGAACGGAACATACATGGCCTGAAGGTGAATACTCGGGCCGGACCCTCTCAACACAGCA GCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAACTGA AAAAAATACTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTG GTCATGGCAACGGAGGCACAGTCTACAAAGCATATCATGTCCCGAGTGGGAAAATATTAG CTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAAT TGGAAATTCTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTG TAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGGGGATCTTTGGATGTATATA GGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTT ATTTGTGGAGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACA CAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACTCAGCTGGTGAATTCTATAG CCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGT ATGGAATTCATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGA GGTTTCCATATCCTCAGATTCAGAAAAACCAGGGATCTTTAATGCCTCTCCAGCTTCTGC AGTGCATTGTTGATGAGGATTCGCCCGTCCTTCCAGTTGGAGAGTTCTCGGAGCCATTTG TACATTTCATCACTCAGTGTATGCGAAAACAGCCAAAAGAAAGGCCAGCACCTGAAGAAT TGATGGGCCACCCGTTCATCGTGCAGTTCAATGATGGAAATGCCGCCGTGGTGTCCATGT GGGTGTGCCGGGCGCTGGAGGAGAGGCGGAGCCAGCAGGGGCCCCCGTGAGGCTGCCGCA GGGCACTGAAAGCCCAGGACCAGTAACCAAGGAGAACAACCCACCCGTCGCCCTTCTCCG TATGCTGCCTGCGCCAGAAGAGCTTTGCTGGGCCCTGGCTTCCCTGCCCTCGCCTTCACC TCTGTCAGCA >OriGene 5' read for NM_145160 unedited
NCGTCAAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGTCGCCGCC GCCGCAGCCGCCGCCGGTCCGCGCGGCCTCGGGTGGCCGGAGCTCAGCCTGCGCGCGCCG CGCCCTGTGTCTCCGGGTGGGGCAGAAGACTCGCCCCTTGAACCTCCCGCGGGGACTCTC CGTGGTGTGGCGGCCCTGGGGCTCTTTCTTAATAGCCCCGGACTGAGTCCCCTCCAGTCG AGGACCCTCTCCTAGTCCACTGACGAGCGGTGGACACCTGCCGCTGTATCTCCCCCAAAC CGAGTCCTTGCCCTGCTGCCTCCTCATACCCACACGGCGGCAGAGACCTTCACCATAGCG TTCGCTCAACTCCAGAACCTTCCGACCTCCGCTAGTTCCTGCGGGCCTTTGCCCGCTTCC CGGTGCACCCTCCCCGGGAGACACCTCAGACCCCCGACAGCCTGGGCAGGCTCGGTGCCT GCGGGTGCGTTCCTGATCACCCCTCCCCTCTTCCCTCCCCCTCATCCTCCATTCCCTTGT TTTCACCCTCTGTCCTCTGCCCGTCACTCCCCTTGTCACCTCTTGGAGCCCCCTCCTAAC CAGCGGCCAGTGGGTTTCCCATACCCCAGGATGTGAGCCTCTTTAACCTGTAATGCTGTG GCTAGCCCTTGGCCCCTTTCCTGCCATGGAGAACCAGGTGCTGGTAATTCGCATCAAGAT CCCAAATAGTGGGCGCGGTGGACTGGACAGTGCACTCCGGGCCGCAGTTACTCTTCAGGG ATGTGCTGGATGTGATGGGCCAGGTTCTGCCTGAAAGCACACTACAGCATTTGAATATGA AATAGAGATGGTGATCGAATACAGGGAAAGTGATGAGGGAATGAGGCCATGCTGTCTATT ATATTCCCAGTATGGACAGCA >OriGene 3' read for NM_145160 unedited
TTTTTTTTTTTTTTTGTCACAAAGCATTAATACTTTTATTCCCATCAGTGATGCTGACGG GCCTGACCCTTTATAGAGAAAAACATTAGGAAAACAGAAGTGGGCAGGGACCCTGGGAGC CTCCATTCTCAATGCCCCACCCTTTACCTCTCTGCCAGTGTCAGCGCCTTCAAACCAGAA GGTATGGGGATGGCCTGGTGGGGTGGGCCACACATGGGGCTCCCCAGGCAAGGCCACCTG CTGACAGAGGTGAAGGCGAGGGCAGGGAAGCCAGGGCCCAGCAAAGCTCTTCTGGCGCAG GCAGCATACGGAGAAGGGCGACGGGTGGGTTGTTCTCCTTGGTTACTGGTCCTGGGCTTT CAGTGCCCTGCGGCAGCCTCACGGGGGCCCCTGCTGGCTCCGCCTCTCCTCCAGCGCCCG GCACACCCACATGGACACCACGGCGGCATTTCCATCATTGAACTGCACGATGAACGGGTG GCCCATCAATTCTTCAGGTGCTGGCCTTTCTTTTGGCTGTTTTCGCATACACTGAGTGAT GAAATGTACAAATGGCTCCGAGAACTCTCCAACTGGAAGGACGGGCGAATCCTCATCAAC AATGCACTGCAGAAGCTGGAGAGGCATTAAAGATCCCTGGTTTTTCTGAATCTGAGGATA TGGAAACCTN |
Restriction Sites | NotI-NotI |
ACCN | NM_145160 |
Insert Size | 2300 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_145160.1, NP_660143.1 |
RefSeq Size | 2381 bp |
RefSeq ORF | 1347 bp |
Locus ID | 5607 |
UniProt ID | Q13163 |
Domains | PB1, pkinase, TyrKc, S_TKc |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Gap junction, MAPK signaling pathway, Neurotrophin signaling pathway |
Gene Summary | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (A). |
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FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC203171 | MAP2K5 (Myc-DDK-tagged)-Human mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 1 |
CNY 5,488.00 |
|
RC203171L1 | Lenti ORF clone of Human mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC203171L2 | Lenti ORF clone of Human mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RC203171L3 | Lenti ORF clone of Human mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC203171L4 | Lenti ORF clone of Human mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
RG203171 | MAP2K5 (tGFP-tagged) - Human mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 1 |
CNY 7,088.00 |