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CD10 (MME) (NM_000902) Human Untagged Clone
CAT＃: SC109440
MME (untagged)-Human membrane metallo-endopeptidase (MME), transcript variant 1
CNY 5,504.00
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CALLA; CD10; CMT2T; NEP; SCA43; SFE |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC109440 sequence for NM_000902 edited (data generated by NextGen Sequencing)
ATGGGCAAGTCAGAAAGTCAGATGGATATAACTGATATCAACACTCCAAAGCCAAAGAAG AAACAGCGATGGACTCCACTGGAGATCAGCCTCTCGGTCCTTGTCCTGCTCCTCACCATC ATAGCTGTGACAATGATCGCACTCTATGCAACCTACGATGATGGTATTTGCAAGTCATCA GACTGCATAAAATCAGCTGCTCGACTGATCCAAAACATGGATGCCACCACTGAGCCTTGT ACAGACTTTTTCAAATATGCTTGCGGAGGCTGGTTGAAACGTAATGTCATTCCCGAGACC AGCTCCCGTTACGGCAACTTTGACATTTTAAGAGATGAACTAGAAGTCGTTTTGAAAGAT GTCCTTCAAGAACCCAAAACTGAAGATATAGTAGCAGTGCAGAAAGCAAAAGCATTGTAC AGGTCTTGTATAAATGAATCTGCTATTGATAGCAGAGGTGGAGAACCTCTACTCAAACTG TTACCAGACATATATGGGTGGCCAGTAGCAACAGAAAACTGGGAGCAAAAATATGGTGCT TCTTGGACAGCTGAAAAAGCTATTGCACAACTGAATTCTAAATATGGGAAAAAAGTCCTT ATTAATTTGTTTGTTGGCACTGATGATAAGAATTCTGTGAATCATGTAATTCATATTGAC CAACCTCGACTTGGCCTCCCTTCTAGAGATTACTATGAATGCACTGGAATCTATAAAGAG GCTTGTACAGCATATGTGGATTTTATGATTTCTGTGGCCAGATTGATTCGTCAGGAAGAA AGATTGCCCATCGATGAAAACCAGCTTGCTTTGGAAATGAATAAAGTTATGGAATTGGAA AAAGAAATTGCCAATGCTACGGCTAAACCTGAAGATCGAAATGATCCAATGCTTCTGTAT AACAAGATGACATTGGCCCAGATCCAAAATAACTTTTCACTAGAGATCAATGGGAAGCCA TTCAGCTGGTTGAATTTCACAAATGAAATCATGTCAACTGTGAATATTAGTATTACAAAT GAGGAAGATGTGGTTGTTTATGCTCCAGAATATTTAACCAAACTTAAGCCCATTCTTACC AAATATTCTGCCAGAGATCTTCAAAATTTAATGTCCTGGAGATTCATAATGGATCTTGTA AGCAGCCTCAGCCGAACCTACAAGGAGTCCAGAAATGCTTTCCGCAAGGCCCTTTATGGT ACAACCTCAGAAACAGCAACTTGGAGACGTTGTGCAAACTATGTCAATGGGAATATGGAA AATGCTGTGGGGAGGCTTTATGTGGAAGCAGCATTTGCTGGAGAGAGTAAACATGTGGTC GAGGATTTGATTGCACAGATCCGAGAAGTTTTTATTCAGACTTTAGATGACCTCACTTGG ATGGATGCCGAGACAAAAAAGAGAGCTGAAGAAAAGGCCTTAGCAATTAAAGAAAGGATC GGCTATCCTGATGACATTGTTTCAAATGATAACAAACTGAATAATGAGTACCTCGAGTTG AACTACAAAGAAGATGAATACTTCGAGAACATAATTCAAAATTTGAAATTCAGCCAAAGT AAACAACTGAAGAAGCTCCGAGAAAAGGTGGACAAAGATGAGTGGATAAGTGGAGCAGCT GTAGTCAATGCATTTTACTCTTCAGGAAGAAATCAGATAGTCTTCCCAGCCGGCATTCTG CAGCCCCCCTTCTTTAGTGCCCAGCAGTCCAACTCATTGAACTATGGGGGCATCGGCATG GTCATAGGACACGAAATCACCCATGGCTTCGATGACAATGGCAGAAACTTTAACAAAGAT GGAGACCTCGTTGACTGGTGGACTCAACAGTCTGCAAGTAACTTTAAGGAGCAATCCCAG TGCATGGTGTATCAGTATGGAAACTTTTCCTGGGACCTGGCAGGTGGACAGCACCTTAAT GGAATTAATACACTGGGAGAAAACATTGCTGATAATGGAGGTCTTGGTCAAGCATACAGA GCCTATCAGAATTATATTAAAAAGAATGGCGAAGAAAAATTACTTCCTGGACTTGACCTA AATCACAAACAACTATTTTTCTTGAACTTTGCACAGGTGTGGTGTGGAACCTATAGGCCA GAGTATGCGGTTAACTCCATTAAAACAGATGTGCACAGTCCAGGCAATTTCAGGATTATT GGGACTTTGCAGAACTCTGCAGAGTTTTCAGAAGCCTTTCACTGCCGCAAGAATTCATAC ATGAATCCAGAAAAGAAGTGCCGGGTTTGGTGA Clone variation with respect to NM_000902.3 >OriGene 5' read for NM_000902 unedited
GGTGTTCGAATTTTGTAATACGACTCACTATAGGGCGGCCCGCGAATTCGCACGAGCAGC AGCCTCCAACTTCTCCCGAATCCCACTGATTTTAGGTGATGGGCAAGTCAGAAAGTCAGA TGGATATAACTGATATCAACACTCCAAAGCCAAAGAAGAAACAGCGATGGACTCCACTGG AGATCAGCCTCTCGGTCCTTGTCCTGCTCCTCACCATCATAGCTGTGACAATGATCGCAC TCTATGCAACCTACGATGATGGTATTTGCAAGTCATCAGACTGCATAAAATCAGCTGCTC GACTGATCCAAAACATGGATGCCACCACTGAGCCTTGTACAGACTTTTTCAAATATGCTT GCGGAGGCTGGTTGAAACGTAATGTCATTCCCGAGACCAGCTCCCGTTACGGCAACTTTG ACATTTTAAGAGATGAACTAGAAGTCGTTTTGAAAGATGTCCTTCAAGAACCCAAAACTG AAGATATAGTAGCAGTGCAGAAAGCAAAAGCATTGTACAGGTCTTGTATAAATGAATCTG CTATTGATAGCAGAGGTGGAGAACCTCTACTCAAACTGTTACCAGACATATATGGGTGGC CAGTAGCAACAGAAAACTGGGAGCAAAAATATGGTGCTTCTTGGACAGCTGAAAAAGCTA TTGCACAACTGAATTCTAAATATGGGAAAAAAGTCCTTATTAATTTGTTTGTTGGCACTG ATGATAAGAATTCTGTGAATCATGTAATTCATATTGACCAACCTCGACTTGGCCTCCCTT CTAGAGATACTATGAATGCACTGGAAATCTATAAGAGGCTTGTACAGCATATGTGGATTT TATGAATTCTGTGGCCAGAATGATTCGTCAGGAAGAAAGATTGCCATCGATGAAACCAGC TTGCTTTGGAATGAATAAAGTATGGAA >OriGene 3' read for NM_000902 unedited
CCCCATTTGTTGCCCGCCGGCCGCATTCTACATCGCGTTTTTTTTTTTTTTTTTTACCAT CACCAACGTTTGTTTTTATTTTGCATTTTTGAGACTGGAAACTGATAAACATTTCTGATT AGGAAACTTTGACAATACAGTCTTTCTTCTTTCCAAAATAACAAATGTCTTTTAGTTTGA GAGCTCCAGCTGTGGCAACAAGAATGATAAATGCTTTTGAGAAAATTAGCACGGTTTTGC CCCACTTAAATGGTTAACAGTAACAGTAGTACAGACCCAAACTTGACAAAACTTTGGCAC TTGTTATTTGGACTAAAATTTTGTCTCACTCCATTCACACACGTCCATGGGAGTTTTCAG TTTATCCTGCCCACTGATTCATACCTGGCAGACCGATTCCCTGGGACGGCAGCATTGGAC ACCTACTCCTTCTCTCGCTGACAACCACCAATATACTCTAATTCTCTTTTTCTAGGCGAG AGACGCCCCGGCCCACCGGAAAATTGCACACCCCCCAGGCCCCCCTCGCCCGAGCGCCAC ACCCCGCCCCCAACAGGCACTTTTTCCTTGCCCCGCTGCCCTTCCAATCCTTCCACTTCG CCCCTCCCTCCCACCAACACCGCTCCTCGCAGCTATCTTCCTCCCCACCCCCCCCTGCCC CCCGCCCCTTCTCCCCACCTCTCTCGCCACTTTCCTACCTCTCCAACCATTTTTGTCTAT AAAAATTTATCAATTCCCTCTCTTCCCCCCATACCCTCCTCCCTCTCACCCCTCGTCTCT ACTGCCCGTCACACACCCCAAACGCCCCCCCTGCCCGTCCCAACCCACCACGACGCCGCC CCCCCGCCTCACCCATCACACATAGTCATCCCACCCCATCCCCCCCTCAACTCCCTCCCC ACTCCCTCCCTCTCCGCCTCCTCCCCACCCGCTCCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000902 |
| Insert Size | 5850 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000902.2, NP_000893.1 |
| RefSeq Size | 5595 bp |
| RefSeq ORF | 2253 bp |
| Locus ID | 4311 |
| UniProt ID | P08473 |
| Domains | Peptidase_M13 |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Protein Pathways | Alzheimer's disease, Hematopoietic cell lineage, Renin-angiotensin system |
| Gene Summary | The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017] Transcript Variant: This variant (1) contains an alternate 5' UTR exon compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a). |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223013 | MME (Myc-DDK-tagged)-Human membrane metallo-endopeptidase (MME), transcript variant 1 |
CNY 5,496.00 |
|
| RC223013L1 | Lenti ORF clone of Human membrane metallo-endopeptidase (MME), transcript variant 1, Myc-DDK-tagged |
CNY 7,896.00 |
|
| RC223013L2 | Lenti ORF clone of Human membrane metallo-endopeptidase (MME), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC223013L3 | Lenti ORF clone of Human membrane metallo-endopeptidase (MME), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC223013L4 | Lenti ORF clone of Human membrane metallo-endopeptidase (MME), transcript variant 1, mGFP tagged |
CNY 7,896.00 |
|
| RG223013 | MME (tGFP-tagged) - Human membrane metallo-endopeptidase (MME), transcript variant 1 |
CNY 7,096.00 |
