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CD10 (MME) (NM_007289) Human Untagged Clone
CAT＃: SC108798
MME (untagged)-Human membrane metallo-endopeptidase (MME), transcript variant 2b
CNY 5,504.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CALLA; CD10; CMT2T; NEP; SCA43; SFE |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_007289, the custom clone sequence may differ by one or more nucleotides
ATGGGCAAGTCAGAAAGTCAGATGGATATAACTGATATCAACACTCCAAAGCCAAAGAAGAAACAGCGAT GGACTCCACTGGAGATCAGCCTCTCGGTCCTTGTCCTGCTCCTCACCATCATAGCTGTGACAATGATCGC ACTCTATGCAACCTACGATGATGGTATTTGCAAGTCATCAGACTGCATAAAATCAGCTGCTCGACTGATC CAAAACATGGATGCCACCACTGAGCCTTGTACAGACTTTTTCAAATATGCTTGCGGAGGCTGGTTGAAAC GTAATGTCATTCCCGAGACCAGCTCCCGTTACGGCAACTTTGACATTTTAAGAGATGAACTAGAAGTCGT TTTGAAAGATGTCCTTCAAGAACCCAAAACTGAAGATATAGTAGCAGTGCAGAAAGCAAAAGCATTGTAC AGGTCTTGTATAAATGAATCTGCTATTGATAGCAGAGGTGGAGAACCTCTACTCAAACTGTTACCAGACA TATATGGGTGGCCAGTAGCAACAGAAAACTGGGAGCAAAAATATGGTGCTTCTTGGACAGCTGAAAAAGC TATTGCACAACTGAATTCTAAATATGGGAAAAAAGTCCTTATTAATTTGTTTGTTGGCACTGATGATAAG AATTCTGTGAATCATGTAATTCATATTGACCAACCTCGACTTGGCCTCCCTTCTAGAGATTACTATGAAT GCACTGGAATCTATAAAGAGGCTTGTACAGCATATGTGGATTTTATGATTTCTGTGGCCAGATTGATTCG TCAGGAAGAAAGATTGCCCATCGATGAAAACCAGCTTGCTTTGGAAATGAATAAAGTTATGGAATTGGAA AAAGAAATTGCCAATGCTACGGCTAAACCTGAAGATCGAAATGATCCAATGCTTCTGTATAACAAGATGA CATTGGCCCAGATCCAAAATAACTTTTCACTAGAGATCAATGGGAAGCCATTCAGCTGGTTGAATTTCAC AAATGAAATCATGTCAACTGTGAATATTAGTATTACAAATGAGGAAGATGTGGTTGTTTATGCTCCAGAA TATTTAACCAAACTTAAGCCCATTCTTACCAAATATTCTGCCAGAGATCTTCAAAATTTAATGTCCTGGA GATTCATAATGGATCTTGTAAGCAGCCTCAGCCGAACCTACAAGGAGTCCAGAAATGCTTTCCGCAAGGC CCTTTATGGTACAACCTCAGAAACAGCAACTTGGAGACGTTGTGCAAACTATGTCAATGGGAATATGGAA AATGCTGTGGGGAGGCTTTATGTGGAAGCAGCATTTGCTGGAGAGAGTAAACATGTGGTCGAGGATTTGA TTGCACAGATCCGAGAAGTTTTTATTCAGACTTTAGATGACCTCACTTGGATGGATGCCGAGACAAAAAA GAGAGCTGAAGAAAAGGCCTTAGCAATTAAAGAAAGGATCGGCTATCCTGATGACATTGTTTCAAATGAT AACAAACTGAATAATGAGTACCTCGAGTTGAACTACAAAGAAGATGAATACTTCGAGAACATAATTCAAA ATTTGAAATTCAGCCAAAGTAAACAACTGAAGAAGCTCCGAGAAAAGGTGGACAAAGATGAGTGGATAAG TGGAGCAGCTGTAGTCAATGCATTTTACTCTTCAGGAAGAAATCAGATAGTCTTCCCAGCCGGCATTCTG CAGCCCCCCTTCTTTAGTGCCCAGCAGTCCAACTCATTGAACTATGGGGGCATCGGCATGGTCATAGGAC ACGAAATCACCCATGGCTTCGATGACAATGGCAGAAACTTTAACAAAGATGGAGACCTCGTTGACTGGTG GACTCAACAGTCTGCAAGTAACTTTAAGGAGCAATCCCAGTGCATGGTGTATCAGTATGGAAACTTTTCC TGGGACCTGGCAGGTGGACAGCACCTTAATGGAATTAATACACTGGGAGAAAACATTGCTGATAATGGAG GTCTTGGTCAAGCATACAGAGCCTATCAGAATTATATTAAAAAGAATGGCGAAGAAAAATTACTTCCTGG ACTTGACCTAAATCACAAACAACTATTTTTCTTGAACTTTGCACAGGTGTGGTGTGGAACCTATAGGCCA GAGTATGCGGTTAACTCCATTAAAACAGATGTGCACAGTCCAGGCAATTTCAGGATTATTGGGACTTTGC AGAACTCTGCAGAGTTTTCAGAAGCCTTTCACTGCCGCAAGAATTCATACATGAATCCAGAAAAGAAGTG CCGGGTTTGGTGA >OriGene 5' read for NM_007289 unedited
NTGTCANATTTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACCAGTGGAGGAGG GCTCTGGAAGTCACGTCAGGTTGGCTCTTCAGGTTCATTTCCATAGTTCCCTGCGGCCTC TGCCTTGGGGAGTTATGTTTTGTTACCGAGATCCGCGCTACCAGATTGCACCGGGGCTGA TTTGGGGGCTGGGAATTTGCCATTCTGCTGTACAGACACTGATTTTTTTTTCTTCTTTTT AAAAAGCAAGATTTTAGGTGATGGGCAAGTCAGAAAGTCAGATGGATATAACTGATATCA ACACTCCAAAGCCAAAGAAGAAACAGCGATGGACTCCACTGGAGATCAGCCTCTCGGTCC TTGTCCTGCTCCTCACCATCATAGCTGTGACAATGATCGCACTCTATGCAACCTACGATG ATGGTATTTGCAAGTCATCAGACTGCATAAAATCAGCTGCTCGACTGATCCAAAACATGG ATGCCACCACTGAGCCTTGTACAGACTTTTTCAAATATGCTTGCGGAGGCTGGTTGAAAC GTAATGTCATTCCCGAGACCAGCTCCCGTTACGGCAACTTTGACATTTTAAGAGATGAAC TAGAAGTCGTTTTGAAAGATGTCCTTCAAGAACCCAAAACTGAAGATATAGTAGCAGTGC AGAAAGCAAAAGCATTGTACAGGTCTTGTATAAATGAATCTGCTATTGATAGCAGAGGTG GAGAACCTCTACTCAAACTGTTACCAGACATATATGGGGTGGCCAGTAGCAACAGAAAAC TGGNGAGCAAAATATGGTGNCTTCTTGGACAGCTGAAAAAGCTTTTGCACAACTGAAATT CTAATATGGGAAANAAAGTCCCTTATNNATTTGNTTGNTGGCACTGATGATAAGAAANCT GTGAATCATGGTATTCATATTGACCAACCTCGACTTGGCCTCCCTTCTAGAGATACTAT >OriGene 3' read for NM_007289 unedited
CCGCGGCCGCATTCTANATCGAGTTTTTTTTTTTTTTTTTTTATTAAAAACGTTTGTTTT TATTTTGTATTTTTGAGACTGGAAACTGATAAAAATTTCTGATTAGGAAACTTTGAGAAT AGAGTCTTTCTTCTTTCCAAAATAACAAATGTCTTTTAGTTTGAGAGCTCCAGCTGTGGC AACAAGAATGATAAATGCTTTTGAGAAAATTACCAAGGTTTTGCCCCACTTAAATGGTTA ACAGTAACAGTAGTACAGACCCAAACTTGATAAAACTTTGGCACTTGCTATCTGGACTAA ACTTTTGTCTCCCTCGACCCACACACTTAAACGGGAGTTCCCAGTCTATCCCCCCCACCG ATTTATACCTGGTAGACCCACCCTGGCAAGGCACCCTTGCCCCATTCTACCTCTCTTGCT GACACCCCCCTTCTTACCCACTCCCCTCTCCTTAGCCGACAGAACCCCACGTCCCCGGAC CCCCGCCCCACTCCTCCCCCCCCCTGCTCTCAACGCTTTTCTCTTCTCCCCCCCACCTCC CCCCTTATGTCCCCTTCCCCCCCCCCCCCCCCCCCTCACCCCTCCCCCCTCTCTTTTCCC TCCCCCCTTTTTTTCCTCCCCTCTTGTTCCCCCCCTTTCTCCCCCCATTTTTTCCCCCCT TCCCTATTCCCCTTCTCTTTTCCCCCCTCTTCACCCCCCCTACCCCTCGCCCCCCCCTCC TTCCCCCTATCCTCCGCCCTTCTCCCACCCCGCCTCCCCCCATATTTCCCCCCACCCCGT CTTTCTCCCCCCCAATTACTCCTCCCCCGTCCCTCCTCTCCACCCTTCCAATCTTCCTCC CCCCCCCCCCGCCCCTCTCTCCTCCCTCCCTTTTTCTTCTCCACCCGCCCCCCTACCCCT CCCCCCCCCTCCCCTCCTTTTCCCCTCCCTCCCTCCTTCCCCGTTCCCCCCCCCCCCCCC CCCTTCTCTCCTCTTCCCCCTATCATCCTCCCATTAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007289 |
| Insert Size | 5850 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007289.1, NP_009220.1 |
| RefSeq Size | 5725 bp |
| RefSeq ORF | 2253 bp |
| Locus ID | 4311 |
| UniProt ID | P08473 |
| Domains | Peptidase_M13 |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Protein Pathways | Alzheimer's disease, Hematopoietic cell lineage, Renin-angiotensin system |
| Gene Summary | The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017] Transcript Variant: This variant (2b) is the longest transcript and includes alternate exon 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Clinicopathologic features and prognostic factors in patients with renal cell carcinoma with sarcomatoid differentiation.
,null,
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
,PubMed ID 32048364
[MME]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223116 | MME (Myc-DDK-tagged)-Human membrane metallo-endopeptidase (MME), transcript variant 2b |
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| RC223116L3 | Lenti ORF clone of Human membrane metallo-endopeptidase (MME), transcript variant 2b, Myc-DDK-tagged |
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| RC223116L4 | Lenti ORF clone of Human membrane metallo-endopeptidase (MME), transcript variant 2b, mGFP tagged |
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| RG223116 | MME (tGFP-tagged) - Human membrane metallo-endopeptidase (MME), transcript variant 2b |
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