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DUSP3 (NM_004090) Human Untagged Clone
CAT＃: SC108794
DUSP3 (untagged)-Human dual specificity phosphatase 3 (DUSP3)
CNY 2,400.00
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | VHR |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108794 sequence for NM_004090 edited (data generated by NextGen Sequencing)
ATGTCGGGCTCGTTCGAGCTCTCGGTGCAGGATCTCAACGACCTGCTCTCGGACGGCAGC GGCTGCTACAGCCTCCCGAGCCAGCCCTGCAACGAGGTCACCCCGCGGATCTACGTGGGC AACGCGTCTGTGGCTCAGGACATCCCCAAGCTGCAGAAACTAGGCATCACCCATGTGCTG AACGCGGCTGAGGGCAGGTCCTTCATGCACGTCAACACCAATGCCAACTTCTACAAGGAC TCCGGCATCACATACCTGGGCATCAAGGCCAACGACACACAGGAGTTCAACCTCAGCGCT TACTTTGAAAGGGCTGCCGACTTCATTGACCAGGCTTTGGCTCAAAAGAATGGCCGGGTG CTCGTCCACTGCCGGGAAGGTTATAGCCGCTCCCCAACGCTAGTTATCGCCTACCTCATG ATGCGGCAGAAGATGGACGTCAAGTCTGCCCTGAGCATCGTGAGGCAGAACCGTGAGATC GGCCCCAACGATGGCTTCCTGGCCCAGCTCTGCCAGCTCAATGACAGACTAGCCAAGGAG GGGAAGTTGAAACCCTAG Clone variation with respect to NM_004090.3 >OriGene 5' read for NM_004090 unedited
CAACAATTTGTAATACGACTCACTATAGGGCGGCCGCGNAATTCGCACGAGGGCCTCGCT TGCTCCTGCCGGGCGTGCAGGGCCCCGCCGCCGCCATGTCGGGCTCGTTCGAGCTCTCGG TGCAGGATCTCAACGACCTGCTCTCGGACGGCAGCGGCTGCTACAGCCTCCCGAGCCAGC CCTGCAACGAGGTCACCCCGCGGATCTACGTGGGCAACGCGTCTGTGGCTCAGGACATCC CCAAGCTGCAGAAACTAGGCATCACCCATGTGCTGAACGCGGCTGAGGGCAGGTCCTTCA TGCACGTCAACACCAATGCCAACTTCTACAAGGACTCCGGCATCACATACCTGGGCATCA AGGCCAACGACACACAGGAGTTCAACCTCAGCGCTTACTTTGAAAGGGCTGCCGACTTCA TTGACCAGGCTTTGGCTCAAAAGAATGGCCGGGTGCTCGTCCACTGCCGGGAAGGTTATA GCCGCTCCCCAACGCTAGTTATCGCCTACCTCATGATGCGGCAGAAGATGGACGTCAAGT CTGCCCTGAGCATCGTGAGGCAGAACCGTGAGATCGGCCCCAACGATGGCTTCCTGGCCC AGCTCTGCCAGCTCAATGACAGACTAGCCAAGGAGGGGAAGTTGAAACCCTAGGGCACCC CCACCGCCTCTGCTCGAGAGGTCCGTGGGGGAGGCCGTGGGCAAAGGTGTCCCGAGCTGC CATGTTTAAGAAACACACTGTACCCTGCTCCCAGCATCACAAAGCACTTGTCTACAAGTG TGTCCCAACACAGTCCTGNGCCACTTTCCCCACCCTGGGGAGCACATAAAGAAAGCTGCC CAGGGGGGCGTNCCTGCTCCCCAGNTGGCCTGGTTCTGTACTCATGAAGNCTTTTCCTGA GAAGGGGCTCANAGGGGGAAGCCTGGGCCTGCAGCTTCCGAGG >OriGene 3' read for NM_004090 unedited
ATACTTTGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTCCTTTA AAACAGTAGCATCTTAACTTGTGGCACAAAAGGCACCAACATTCCCTTTCCAAACCATCC ATCACCATGGGTGGAAGGCAGCGCCACCTGCTGGCCATCATATTATGGCTCACATACCCA TAATTTCCTTGCGGTGCTGAATTCCAAGTGGGGATTATTAGAGACCCCTCAGAGCCAAAA GGGGACCTTAGAGGTCTTCTAGATGAGTCCCCTCATTTGTAGGTGGTGGTTTCTGGATAA CTCAGAGTGGCAGGGACACAGACGAGCCTGTGGAAAGGTATACTGCTTTAAGATTGAGAA GAAAACCATTTGGCGCTCTAATTTTGCCTGGATGGTGCTCTGTCAGCCAAAGAAAGGGAA CAGGTCTGGGGAGGGGGTAAGGGCACCCTGAGTTCCTGTTCCATCACTTCCCAGGCAGTA GAAGGCTGTCCAGGAACAGTTCCCATCCGCAGCTGGGCATGTGTTGGCTCTTACACAAGA GACTCTACTTTTACTTGACGAACTAAGACCCAATCTTCCACAGTAAATACGGCGCCTCAG GGCCGAAGGACTATCACCAAACCTCAGTTATCTATTAAACCTACTCTCCACCGCCAGGGA GTAACTTTCCAAATGCCCATTCTCCCCCATGCCCACCACAACCTCCATACCCCCTCTTTC TTCCCCCCCCACCCTCCCCTTGCCCGTTCACCTGTCTGATTTGCCCCATCCGCTATTAAC TTTCCGTACCTCCTTACGNTACCCCCCACCCTTTTTCCTGTCCTTTACACTAGTTTAGTT TAATCCTTTTATGCCCCCCTCCGCCCCCCCCCTTCTTATCTCCCTTCCCTCCCTGTTCCC CCCCCCTCTCCTTCCTTTTTTTTTCCCCCCCTTCTCTTCCTCCCTTCCCTCTTCCTACTC C |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004090 |
| Insert Size | 3670 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004090.2, NP_004081.1 |
| RefSeq Size | 4116 bp |
| RefSeq ORF | 558 bp |
| Locus ID | 1845 |
| UniProt ID | P51452 |
| Domains | DSPc |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | MAPK signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1. [provided by RefSeq, Jul 2008] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201119 | DUSP3 (Myc-DDK-tagged)-Human dual specificity phosphatase 3 (DUSP3) |
CNY 2,400.00 |
|
| RC201119L1 | Lenti ORF clone of Human dual specificity phosphatase 3 (DUSP3), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201119L2 | Lenti ORF clone of Human dual specificity phosphatase 3 (DUSP3), mGFP tagged |
CNY 5,890.00 |
|
| RC201119L3 | Lenti ORF clone of Human dual specificity phosphatase 3 (DUSP3), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201119L4 | Lenti ORF clone of Human dual specificity phosphatase 3 (DUSP3), mGFP tagged |
CNY 5,890.00 |
|
| RG201119 | DUSP3 (tGFP-tagged) - Human dual specificity phosphatase 3 (DUSP3) |
CNY 4,000.00 |
