OTUB1 (NM_017670) Human Untagged Clone
CAT#: SC108722
OTUB1 (untagged)-Human OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1
CNY 2,400.00
CNY 2,950.00
Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | HSPC263; OTB1; OTU1 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_017670 edited
GAATTCGGCACGAGGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCA GCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGA TGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCT GGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACAT CTATCAACAGAAGATCAAGGACCTCCACAAAAAGTACTCGTACATCCGCAAGACCAGGCC TGACGGCAACTGTTTCTATCGGGCTTTCGGATTCTCCCACTTGGAGGCACTGCTGGATGA CAGCAAGGAGTTGCAGCGGTTCAAGGCTGTGTCTGCCAAGAGCAAGGAAGACCTGGTGTC CCAGGGCTTCACTGAATTCACAATTGAGGATTTCCACAACACGTTCATGGACCTGATTGA GCAGGTGGAGAAGCAGACCTCTGTCGCCGACCTGCTGGCCTCCTTCAATGACCAGAGCAC CTCCGACTACCTTGTGGTCTACCTGCGGCTGCTCACCTCGGGCTACCTGCAGCGCGAGAG CAAGTTCTTCGAGCACTTCATCGAGGGTGGACGGACTGTCAAGGAGTTCTGCCAGCAGGA GGTGGAGCCCATGTGCAAGGAGAGCGACCACATCCACATCATTGCGCTGGCCCAGGCCCT CAGCGTGTCCATCCAGGTGGAGTACATGGACCGCGGCGAGGGCGGCACCACCAATCCGCA CATCTTCCCTGAGGGCTCCGAGCCCAAGGTCTACCTTCTCTACCGGCCTGGACACTACGA TATCCTCTACAAATAGGGCTGGCTCCAGCCCGCTGCTGCCCTGCTGCCCCCCTCTGCCAG GCGCTAGACATGTACAGAGGTTTTTCTGTGGTTGTAAATGGTCCTATTTCACCCCCTTCT TCCTGTCACATGACCCCCCCCCATGTTTTATTAAAGGGGGTGCTGGTGGTGAAAAAAAAA AAAAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_017670 unedited
GGGGGTCAAATTTGTATACGACTCCTATAGGCGGCCCGCGAATTCGCACGAGGGTCGGTA GTGCGGCGCTGTTTAAAGAGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGG GCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGG ACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCT CGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGACC TCCACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTGACGGCAACTGTTTCTATCGGG CTTTCGGATTCTCCCACTTGGAGGCACTGCTGGATGACAGCAAGGAGTTGCAGCGGTTCA AGGCTGTGTCTGCCAAGAGCAAGGAAGACCTGGTGTCCCAGGGCTTCACTGAATTCACAA TTGAGGATTTCCACAACACGTTCATGGACCTGATTGAGCAGGTGGAGAAGCAGACCTCTG TCGCCGACCTGCTGGCCTCCTTCAATGACCAGAGCACCTCCGACTACCTTGTGGTCTACC TGCGGCTGCTCACCTCGGGCTACCTGCAGCGCGAGAGCAAGTTCTTCGAGCACTTCATCG AGGGTGGACGGACTGTCAAGGAGTTCTGCCAGCAGGAGGTGGAGCCCATGTGCAAGGAGA GCGACCACATCCACATCATTGCGCTGGCCCAGGCCCTCAGCGTGTCCATCCCAGTGGAGT ACATGGACCGCGGCGAGGGCGGCACCACCAATCCGCACATCTTCCCCTGAGGCTCCGAGC CCCAGGTCTACCTTCTCTACCGGCCTGGACACTACGATATCCTCTACAAATAGGGCTGGC TTCAN >OriGene 3' read for NM_017670 unedited
TATGGATCGCGGGCCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TCACCACCAGCACCCCCTTTAATAAAACATGNGGGGGGGGTCATGTGACAGGAAAAAGGG GGTGAAATAGGACCATTTACAACCACAAAAAAACCTTTGTACATGTCTACCGCCTGGCAA AGGGGGGCAGCAGGGCAGCAGCGGGCTGGAGCCAGCCCTATTTGTAAAGGATATCGTAGT GTCCAGGCCGGTAAAAAAGGTAAACCTTGGGCTCGGAGCCCTCAGGGAAAATGTGCGGAT TGGTGGTGCCGCCCTCGCCGCGGCCCATGTACTCCACCTGGATGGACACGCTGAGGGCCT GGGCCAGCGCAATGATGTGGATGTGGCCGCTCTCCTTGCACATGGGCTCCACCTCCTGCT GGCAAAACTCCTTGACAGTCCGTCCACCCTCGATGAAGTGCTCGAAAAACTTGCTCTCGC GCTGAAGGTATCCCGAGGTGAACACCCCCAAGTAAACCACATGGTATTCGCAGGCGCTCT GGTCATTGAAGGAGGCCAGAAGGTCGGCAACAGAGGTCTGCTTTTTCACCTGTTCAATCA GGTCCATGAACCGGTTGCGCAAACTCCTAATTGTCAACTCAGTGAATCCCTGGGACACCT GTCCTTTCTTGCTTTTGCCAAACACACCCTTGAACCGTTGCCCTCCTTTCCTGAATTCCA ACAGCGCCCCCAATGGGGAAAATTCCCATACCCCTTAACAAAACAATCCCCTCCACGCCT GTCCCTTGCGTATTGACAACTCTTTTTGTAGGAAGTCCCTTCACCTCCCCGTCCAAAAAG CCCGCCCCTTTTCACACTATCTTCCTTCTATGCACACAAGATCCCCCCACCTTATG |
Restriction Sites | NotI-NotI |
ACCN | NM_017670 |
Insert Size | 1090 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_017670.1, NP_060140.1 |
RefSeq Size | 1747 bp |
RefSeq ORF | 816 bp |
Locus ID | 55611 |
UniProt ID | Q96FW1 |
Protein Families | Protease |
Gene Summary | The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the predominant transcript. |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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OTU Domain-containing Ubiquitin Aldehyde-binding Protein 1 (OTUB1) Deubiquitinates Estrogen Receptor (ER) and Affects ER Transcriptional Activity
,Vladimir Stanisic, Anna Malovannaya, Jun Qin, David M. Lonard, and Bert W. O'Malley,
J. Biol. Chem., Jun 2009; 284: 16135 - 16145.
[OTUB1]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC210648 | OTUB1 (Myc-DDK-tagged)-Human OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1 |
CNY 3,990.00 |
|
RC210648L1 | Lenti ORF clone of Human OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
RC210648L2 | Lenti ORF clone of Human OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RC210648L3 | Lenti ORF clone of Human OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC210648L4 | Lenti ORF clone of Human OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RG210648 | OTUB1 (tGFP-tagged) - Human OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1 |
CNY 4,000.00 |