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SMPDL3B (NM_014474) Human Untagged Clone
CAT＃: SC108594
SMPDL3B (untagged)-Human sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 1
CNY 3,656.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ASML3B |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108594 sequence for NM_014474 edited (data generated by NextGen Sequencing)
ATGAGGCTGCTCGCCTGGCTGATTTTCCTGGCTAACTGGGGAGGTGCCAGGGCTGAACCA GGTAAGTTCTGGCACATCGCTGACCTGCACCTTGACCCTGACTACAAGGTATCCAAAGAC CCCTTCCAGGTGTGCCCATCAGCTGGATCCCAGCCAGTGCCCGACGCAGGCCCCTGGGGT GACTACCTCTGTGATTCTCCCTGGGCCCTCATCAACTCCTCCATCTATGCCATGAAGGAG ATTGAGCCAGAGCCAGACTTCATTCTCTGGACTGGTGATGACACGCCTCATGTGCCCGAT GAGAAACTGGGAGAGGCAGCTGTACTGGAAATTGTGGAACGCCTGACCAAGCTCATCAGA GAGGTCTTTCCAGATACTAAAGTCTATGCTGCTTTGGGAAATCATGATTTTCACCCCAAA AACCAGTTCCCAGCTGGAAGTAACAACATCTACAATCAGATAGCAGAACTATGGAAACCC TGGCTTAGTAATGAGTCCATCGCTCTCTTCAAAAAAGGTGCCTTCTACTGTGAGAAGCTG CCGGGTCCCAGCGGGGCTGGGCGAATTGTGGTCCTCAACACCAATCTGTACTATACCAGC AATGCGCTGACAGCAGACATGGCGGACCCTGGCCAGCAGTTCCAGTGGCTGGAAGATGTG CTGACCGATGCATCCAAAGCTGGGGACATGGTGTACATTGTCGGCCACGTGCCCCCGGGG TTCTTTGAGAAGACGCAAAACAAGGCATGGTTCCGGGAGGGCTTCAATGAAAAATACCTG AAGGTGGTCCGGAAGCATCATCGCGTCATAGCAGGGCAGTTCTTCGGGCACCACCACACC GACAGCTTTCGGATGCTCTATGATGATGCAGGTGTCCCCATAAGCGCCATGTTCATCACA CCTGGAGTCACCCCATGGAAAACCACATTACCTGGAGTGGTCAATGGGGCCAACAATCCA GCCATCCGGGTGTTCGAATATGACCGAGCCACACTGAGCCTGAAGGACATGGTGACCTAC TTCATGAACCTGAGCCAGGCGAATGCTCAGGGGACGCCGCGCTGGGAGCTCGAGTACCAG CTGACCGAGGCCTATGGGGTGCCGGACGCCAGCGCCCACTCCATGCACACAGTGCTGGAC CGCATCGCTGGCGACCAGAGCACACTGCAGCGCTACTACGTCTATAACTCAGTCAGCTAC TCTGCTGGGGTCTGCGACGAGGCCTGCAGCATGCAGCACGTGTGTGCCATGCGCCAGGTG GACATTGACGCTTACACCACCTGTCTGTATGCCTCTGGCACCACGCCCGTGCCCCAGCTC CCGCTGCTGCTGATGGCCCTGCTGGGCCTGTGCACGCTCGTGCTGTGA Clone variation with respect to NM_014474.2 63 g=>t >OriGene 5' read for NM_014474 unedited
GATTTTGTAATACGACTCACTATAGGGCGGCCCGCGAATTCGCACGAGGACGCCTTGGAG GACTTGGAACACCTGTAACAGGACAAGGAGTCCTGCTCCGGCACGTGGCCACAGAAAACT ACTTAGGAAGCCTGTGGTGAGAACAACAACAGTGCCTGGAGAATCCCACGGCTCTGGGGA AGTGAGCCCCGAGGATGAGGCTGCTCGCCTGGCTGATTTTCCTGGCTAACTGGGGAGGTG CCAGGGCTGAACCAGGTAAGTTCTGGCACATCGCTGACCTGCACCTTGACCCTGACTACA AGGTATCCAAAGACCCCTTCCAGGTGTGCCCATCAGCTGGATCCCAGCCAGTGCCCGACG CAGGCCCCTGGGGTGACTACCTCTGTGATTCTCCCTGGGCCCTCATCAACTCCTCCATCT ATGCCATGAAGGAGATTGAGCCAGAGCCAGACTTCATTCTCTGGACTGGTGATGACACGC CTCATGTGCCCGATGAGAAACTGGGAGAGGCAGCTGTACTGGAAATTGTGGAACGCCTGA CCAAGCTCATCAGAGAGGTCTTTCCAGATACTAAAGTCTATGCTGCTTTGGGAAATCATG ATTTTCACCCCAAAAACCAGTTCCCAGCTGGAAGTAACAACATCTACAATCAGATAGCAG AACTATGGAAACCCTGGCTTAGTAATGAGTCCATCGCTCTCTTCAAAAAGGTGCCTTCTA CTGTGAGAAGCTGCCGGGTCCCAGCGGNGCTGGGCGAATTGTGGTCCTCACACCAATCTG TACTATANCCAGCATGCGCTGACAGCAGACATGGCGGACCCTGGCCAGCAGTTCCAGTGG CTGGAAGATGTGCTGACCGATGCATCCAAGCT >OriGene 3' read for NM_014474 unedited
CGCATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCAAACGCATGATGAGCTTTGTTTTGT GAGTAAAACATAATACGCAAAAGAAGTATGCTTGTAGGGGGGTCTTGGGTCGTCATTTCT TTTCTGTTTCTGGTTTGTTTTTGGAGAGAGTCTGGCTTTGTCGCCCAGGCTGGAGTGCAG TGGCGCGATCACGGATGGCTGCAGCTCCTGGGGCTTCGCTTCCTGATTCGGTTGTCCTAT TTCAGTTCACTCCTCAGGCGCGGAGGAAATGGTGGAAGGCCCAGCTCTGGGTGATCCTGG GCGCTGCCCCCGTTACCCGTTACCAGGAAGAAGGTGAGCCTGGCAGGTCACAGCACGAGC GTGCCACAGGCCCAGCAGGGCCATCAGCAGCAGCGGGAGCTGGGGCACGGTCGTGGTGCC AGAGGCATACAGACAGGTGGTGTAAGCGTCAATGTCCACCTGGCGCATGGCACACACGTG CTGCATGCTGCAGGCCTCGTCGCAGACCCCAGCAGAGTAGCTGACTGAGTTATAGACGTA GTACCGCTGCAGTGTGCTCTGGTCGCCAGCGATGCGGCCCAGCACTGTGTGCATGGAGTG GGCGCTGGCGTTCCGCACCCCATTAGCCTCGTCCAGCTGTCCCTCGAGCTCCCAGCGCGG GCGTCCCCTGAGCATTCCCCTGGCTCAGGCTCATGAAGTAAGTCACCATGCCCTTCAGGC TCAGTGTGGCTCGGTCATATTCGACACCCGGATGGTTGGATTGTGGCCCCATTGCCCCTC CAGNTANTGTGGTTTCCTGGGGTGACTCCAGGGGGATGACATGCGCTTATGGGAACCTGC TTATCTAAACATCCAAAGCTGTGGTGTGTGTGCCCAACACCGCCTTGTTGACCGAGATGC TCCGACCCTTCAGCTTTTTNATTGACCCTCCGGACCTGCTTGTTTGCGTTTTTAAGAACC CGTGTCCCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014474 |
| Insert Size | 1960 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014474.2, NP_055289.2 |
| RefSeq Size | 1890 bp |
| RefSeq ORF | 1368 bp |
| Locus ID | 27293 |
| UniProt ID | Q92485 |
| Domains | Metallophos |
| Protein Families | Secreted Protein |
| Gene Summary | Lipid-modulating phosphodiesterase (PubMed:26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown (PubMed:26095358). Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro) (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
B cell-derived IL-4 acts on podocytes to induce proteinuria and foot process effacement
,Kim, AH;Chung, JJ;Akilesh, S;Koziell, A;Jain, S;Hodgin, JB;Miller, MJ;Stappenbeck, TS;Miner, JH;Shaw, AS;,
JCI Insight
,PubMed ID 29093269
[SMPDL3B]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217688 | SMPDL3B (Myc-DDK-tagged)-Human sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 1 |
CNY 3,656.00 |
|
| RC217688L3 | Lenti ORF clone of Human sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC217688L4 | Lenti ORF clone of Human sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG217688 | SMPDL3B (tGFP-tagged) - Human sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 1 |
CNY 4,370.00 |
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