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spindlin 1 (SPIN1) (NM_006717) Human Untagged Clone
CAT＃: SC108548
SPIN1 (untagged)-Human spindlin 1 (SPIN1)
CNY 2,400.00
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SPIN; TDRD24 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108548 sequence for NM_006717 edited (data generated by NextGen Sequencing)
ATGAAGACCCCATTCGGAAAGACACCTGGCCAGCGGTCCAGAGCTGATGCAGGCCATGCT GGAGTATCTGCCAACATGATGAAGAAGAGGACATCCCACAAAAAACATCGGAGCAGTGTG GGTCCGAGCAAACCTGTTTCCCAGCCCCGGCGGAACATCGTAGGCTGCAGGATTCAGCAT GGGTGGAAAGAGGGGAATGGCCCTGTTACCCAGTGGAAAGGAACCGTTCTGGACCAGGTG CCTGTAAATCCTTCTTTGTATCTTATAAAATACGATGGATTTGACTGTGTTTATGGACTA GAACTTAATAAAGATGAAAGAGTTTCTGCGCTTGAAGTCCTCCCTGATAGAGTTGCGACA TCTCGAATCAGCGATGCACACTTGGCAGACACAATGATTGGCAAAGCAGTGGAACATATG TTTGAGACAGAGGATGGTTCTAAAGATGAGTGGAGGGGAATGGTCTTAGCACGTGCACCT GTCATGAACACATGGTTTTACATTACCTATGAGAAAGACCCTGTCTTGTACATGTACCAA CTCTTAGATGATTACAAAGAAGGCGACCTTCGCATTATGCCTGATTCCAATGATTCACCT CCAGCAGAAAGGGAACCAGGAGAAGTTGTGGACAGCCTGGTAGGCAAACAAGTGGAATAT GCCAAAGAAGATGGCTCGAAAAGGACTGGCATGGTCATTCATCAAGTAGAAGCCAAGCCC TCCGTCTATTTCATCAAGTTTGATGATGATTTCCATATTTATGTCTACGATTTGGTGAAA ACATCCTAG Clone variation with respect to NM_006717.2 >OriGene 5' read for NM_006717 unedited
GAGCCTCGTGCCGAATTCGGCACGAGGATTTTTGCTGAACTCGTAAAAGAGACACTTGGA TGGTGGATTAACCAGAACACTAACATTCTGTGAAAAGTTTCAAATTGGAGAATATTGAAT TTTCACCCTAGTCCAGCAGCTCCGCTGCTCACTTAAATACAGATGAATGAAGACCCCATT CGGAAAGACACCTGGCCAGCGGTCCAGAGCTGATGCAGGCCATGCTGGAGTATCTGCCAA CATGATGAAGAAGAGGACATCCCACAAAAAACATCGGAGCAGTGTGGGTCCGAGCAAACC TGTTTCCCAGCCCCGGCGGAACATCGTAGGCTGCAGGATTCAGCATGGGTGGAAAGAGGG GAATGGCCCTGTTACCCAGTGGAAAGGAACCGTTCTGGACCAGGTGCCTGTAAATCCTTC TTTGTATCTTATAAAATACGATGGATTTGACTGTGTTTATGGACTAGAACTTAATAAAGA TGAAAGAGTTTCTGCGCTTGAAGTCCTCCCTGATAGAGTTGCGACATCTCGAATCAGCGA TGCACACTTGGCAGACACAATGATTGGCAAAGCAGTGGAACATATGTTTGAGACAGANGA TGGTTCTAAAGATGAGTGGAGGGGAATGGTCTTANCACGTGCACCTGTCATGAACACATG GTTTTACATTACCTATGANAAAGACCCTGTCTTGTACATGTACCCAACTCTTANATGATT ACAAAGAAGGCGANCTTCGCATTATGCCTGATTCCATGGATTCACCTNCAGCAGAAAGGG AACCAGGAAAAGTTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006717 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006717.1, NP_006708.1 |
| RefSeq Size | 1506 bp |
| RefSeq ORF | 744 bp |
| Locus ID | 10927 |
| UniProt ID | Q9Y657 |
| Domains | Spin-Ssty |
| Gene Summary | Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway downstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201938 | SPIN1 (Myc-DDK-tagged)-Human spindlin 1 (SPIN1) |
CNY 2,400.00 |
|
| RC201938L1 | Lenti ORF clone of Human spindlin 1 (SPIN1), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201938L2 | Lenti ORF clone of Human spindlin 1 (SPIN1), mGFP tagged |
CNY 5,890.00 |
|
| RC201938L3 | Lenti ORF clone of Human spindlin 1 (SPIN1), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201938L4 | Lenti ORF clone of Human spindlin 1 (SPIN1), mGFP tagged |
CNY 4,800.00 |
|
| RG201938 | SPIN1 (tGFP-tagged) - Human spindlin 1 (SPIN1) |
CNY 4,000.00 |
|
| SC322356 | SPIN1 (untagged)-Human spindlin 1 (SPIN1) |
CNY 2,400.00 |
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