SMC6L1 (SMC6) (NM_024624) Human Untagged Clone

CAT#: SC108334

SMC6 (untagged)-Human structural maintenance of chromosomes 6 (SMC6), transcript variant 2



  "NM_024624" in other vectors (5)

CNY 10,450.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit Polyclonal Anti-SMC6 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms hSMC6; SMC-6; SMC6L1
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_024624, the custom clone sequence may differ by one or more nucleotides


ATGGCCAAAAGAAAGGAAGAAAATTTTTCCTCTCCTAAAAATGCCAAAAGGCCAAGACAAGAAGAATTGG
AGGATTTTGATAAAGATGGTGACGAAGACGAATGTAAAGGTACTACTTTGACTGCAGCAGAAGTTGGAAT
AATTGAGAGTATTCACCTAAAAAACTTCATGTGTCATTCAATGCTTGGACCTTTTAAGTTTGGTTCTAAT
GTCAACTTTGTTGTTGGCAACAATGGAAGTGGGAAGAGTGCAGTACTCACAGCTCTCATAGTCGGTCTTG
GTGGAAGAGCAGTTGCTACTAATAGAGGATCCTCTTTAAAAGGTTTTGTGAAAGATGGACAGAACTCTGC
AGATATCTCAATAACATTGAGGAACAGAGGAGATGATGCCTTTAAAGCCAGTGTGTATGGTAACTCTATA
CTTATACAGCAACACATCAGCATAGATGGAAGTCGATCTTATAAACTTAAAAGTGCAACAGGCTCCGTGG
TTTCCACGAGGAAAGAAGAGCTGATTGCAATTCTTGATCATTTTAACATCCAGGTGGATAATCCAGTTTC
TGTTTTAACACAAGAAATGAGCAAGCAGTTCTTACAGTCTAAAAATGAAGGAGACAAATACAAATTCTTC
ATGAAAGCAACGCAACTTGAACAGATGAAGGAAGATTATTCATACATTATGGAAACGAAAGAAAGAACAA
AGGAGCAGATACATCAAGGAGAAGAGCGGCTTACTGAACTAAAGCGCCAGTGTGTAGAGAAAGAGGAACG
TTTTCAAAGTATTGCTGGTTTAAGTACAATGAAGACTAATTTAGAGTCCTTGAAACATGAAATGGCTTGG
GCAGTGGTCAATGAAATTGAAAAACAATTGAATGCCATCAGAGATAATATCAAAATTGGAGAAGATCGTG
CTGCTAGACTTGACAGGAAAATGGAAGAACAGCAGGTCAGACTTAATGAGGCAGAACAAAAGTACAAGGA
TATTCAAGACAAACTAGAAAAGATTAGTGAAGAGACAAATGCACGAGCACCAGAATGTATGGCATTGAAA
GCAGATGTTGTTGCTAAGAAAAGGGCCTATAATGAAGCTGAGGTTTTATATAACCGATCCTTAAACGAAT
ATAAAGCATTAAAGAAAGATGATGAGCAGCTTTGTAAACGAATTGAAGAGCTGAAAAAAAGTACTGACCA
ATCTTTGGAACCTGAACGGTTGGAAAGACAAAAAAAAATATCTTGGTTAAAAGAGAGAGTAAAGGCCTTT
CAAAATCAAGAAAATTCAGTCAATCAAGAGATCGAACAGTTTCAGCAAGCCATAGAAAAGGACAAAGAAG
AACATGGCAAAATTAAGAGAGAAGAATTAGATGTGAAGCATGCACTGAGCTACAATCAGAGGCAACTGAA
AGAATTGAAAGATAGTAAAACTGATCGACTCAAAAGATTTGGCCCTAATGTTCCAGCTCTTCTTGAAGCC
ATAGATGATGCTTATAGACAAGGACATTTTACCTATAAACCTGTAGGCCCTTTAGGAGCTTGCATTCATC
TTCGGGACCCAGAACTTGCTTTGGCTATTGAATCTTGCTTAAAAGGGCTTCTGCAGGCCTATTGTTGCCA
TAATCATGCTGATGAAAGGGTCCTTCAGGCACTCATGAAAAGGTTTTATTTACCAGGGACCTCACGGCCA
CCGATAATAGTTTCTGAGTTTCGGAATGAGATATATGATGTAAGACACAGAGCTGCTTATCATCCAGACT
TTCCAACAGTTCTGACAGCTTTAGAAATAGATAATGCGGTTGTGGCAAATAGCCTAATTGACATGAGAGG
CATAGAGACAGTGCTACTAATCAAAAATAATTCTGTAGCTCGTGCAGTAATGCAGTCCCAAAAGCCACCC
AAAAATTGTAGAGAAGCTTTTACTGCTGATGGTGATCAAGTTTTTGCAGGACGTTATTATTCATCTGAAA
ATACAAGACCTAAGTTCCTAAGCAGAGATGTGGATTCTGAAATAAGTGACTTGGAGAATGAGGTTGAAAA
TAAGACGGCCCAGATATTAAATCTTCAGCAACATTTATCTGCCCTTGAAAAAGATATTAAACACAATGAG
GAACTTCTTAAAAGGTGCCAACTACATTATAAAGAACTAAAGATGAAAATAAGAAAAAATATTTCTGAAA
TTCGGGAACTTGAGAACATAGAAGAACACCAGTCTGTAGATATTGCAACTTTGGAAGATGAAGCTCAGGA
AAATAAAAGCAAAATGAAAATGGTTGAGGAACATATGGAGCAACAAAAAGAAAATATGGAGCATCTTAAA
AGTCTGAAAATAGAAGCAGAAAATAAGTATGATGCAATTAAATTCAAAATTAATCAACTATCGGAGCTAG
CAGACCCACTTAAGGATGAATTAAACCTTGCTGATTCTGAAGTGGATAACCAAAAACGAGGGAAACGACA
TTATGAAGAAAAACAAAAAGAACACTTGGATACCTTAAATAAAAAGAAACGAGAACTGGATATGAAAGAG
AAAGAACTAGAGGAGAAAATGTCACAAGCAAGACAAATCTGCCCAGAGCGTATAGAAGTAGAAAAATCTG
CATCAATTCTGGACAAAGAAATTAATCGATTAAGGCAGAAGATACAGGCAGAACATGCTAGTCATGGAGA
TCGAGAGGAAATAATGAGGCAGTACCAAGAAGCAAGAGAGACCTATCTTGATCTGGATAGTAAAGTGAGG
ACTTTAAAAAAGTTTATTAAATTACTGGGAGAAATCATGGAGCACAGATTCAAGACATATCAACAATTTA
GAAGGTGTTTGACTTTACGATGCAAATTATACTTTGACAACTTACTATCTCAGCGGGCCTATTGTGGAAA
AATGAATTTTGACCACAAGAATGAAACTCTAAGTATATCAGTTCAGCCTGGAGAAGGAAATAAAGCTGCT
TTCAATGACATGAGAGCCTTGTCTGGAGGTGAACGTTCTTTCTCCACAGTGTGTTTTATTCTTTCCCTGT
GGTCCATCGCAGAATCTCCTTTCAGATGCCTGGATGAATTTGATGTCTACATGGATATGGTTAATAGGAG
AATTGCCATGGACTTGATACTGAAGATGGCAGATTCCCAGCGTTTTAGACAGTTTATCTTGCTCACACCT
CAAAGCATGAGTTCACTTCCATCCAGTAAACTGATAAGAATTCTCCGAATGTCTGATCCTGAAAGAGGAC
AAACTACATTGCCTTTCAGACCTGTGACTCAAGAAGAAGATGATGACCAAAGGTGA


>OriGene 5' read for NM_024624 unedited
TAGAATTTTGGTAATACGACTCACTATAGGGCGGCCGCGATTCGGCACCAGCTGCGGCCG
GCACGCGGTTCCCAGGGGCCAGCGGCGGTCAGCCGAGGTCGAGACGCCCGCAGGGTGGCC
TTAGCGGCCGGTCGTACCACGGCAGCCCCGCCGATCAGGTTCCTTTGGGAGACTTCGACT
TGTTGGCGACCTGATGGCCAAAAGAAAGGAAGAAAATTTTTCCTCTCCTAAAAATGCCAA
AAGGCCAAGACAAGAAGAATTGGAGGATTTTGATAAAGATGGTGACGAAGACGAATGTAA
AGGTACTACTTTGACTGCAGCAGAAGTTGGAATAATTGAGAGTATTCACCTAAAAAACTT
CATGTGTCATTCAATGCTTGGACCTTTTAAGTTTGGTTCTAATGTCAACTTTGTTGTTGG
CAACAATGGAAGTGGGAAGAGTGCAGTACTCACAGCTCTCATAGTCGGTCTTGGTGGAAG
AGCAGTTGCTACTAATAGAGGATCCTCTTTAAAAGGTTTTGTGAAAGATGGACAGAACTC
TGCAGATATCTCAATAACATTGAGGAACAGAGGAGATGATGCCTTTAAAGCCAGTGTGTA
TGGTAACTCTATACTTATACAGCAACACATCAGCATAGATGGAAGTCGATCTTATAAACT
TAAAAGTGCAACAGGCTCCGTGGTTTCCACGAGGAAAGAAGAGCTGNATTGCATTCTTGA
TCATTTTAACATCCAGGTGGATAATCCAGTTTCTGTTTTAACACANAGAAATGAGCAGCA
GTTCTTACAGTCTANAAATGAAGGGAGACAATACANATTCTTCATGAANAGCACGCAACT
TGNACAGATGAAGGNNAGATATTCATACATTATGGNNAACGAAGAAGACCAAGAGCAGAT
CCTCAAGGGAAGAGCGGCTACTGACTAAGCGCATGTGTANAGAAAG
>OriGene 3' read for NM_024624 unedited
CCGCGGCCGCAATTTAGAGTCGAGTTTTTTTTTTTTTTTTTTTATACTCTACTTCATTTT
TAATTTGGAAAAGCACATGTTAAAAATAATTTTAATACAAAGGCATTATAAGTGTAAATT
TAAAAATCAGACTTTGTATGATCAGTGGGAAATGTTTAAAATATTCAGCACACACTTTCC
TCCTCCTGGAAATTCTGATTAGAAAGCCCAAGTTTTTGAACTTCTCATTTGGCAAACCTC
AATTTAAGACTAAAGTATCTTAAACTTCTTCCTCCACCAAAAACACAAACAAAGTCCAGT
TTTCCTCAATAACTAGAGAACAGTCCCTGCTCTTAATATACTGCCCTTTTTCTGAAAATA
GTTCAATTTCATATTTATTCTAATATTTATTGCTACTAATGTAAGGAATGCTTCTTGATA
TCCAATACATTCTTAAAAAGTTTAGCATGAATCCTAGTATCAAACAAATAATACAGGGAG
CAATAAAATTCATGTTTTCTAAAATAAAAAGTTCATAAATATCATTTTTTACAATAACTA
TATTTGGCCATTCTAAGCAGCACACTTTTTAACACCCCTCATTTAGGATGAGTCTTAGAA
TTGATGTCAGCTCACCATCAACTGCCTGGCCTCAGGCTCCTGGAGCCATGACCTACTCTC
CTGCTACATGAGGATCCCCCCCTCCCTCCCAGTTTTCCCAACCCTTCTACCAACCTGATA
TCCCCCAGCCCTCTAGCCTGTGACTCCTCACTGACGACAATCCTGAACAGCCCTTGGCCT
GCACAACTGAGGCCTTTCCAATCCGCCACCCTTGATGGAGTCAAAGGGAAAAACTGGGTC
TTATTCCGTCCCGAACCTGGTTTTACCTCTTTGCTGGGGGACCGTCAAAGGCGGCCCAAC
AGCCTGGGACTAATTGGTCAANCTTCGTGTCCCTCCACGGGCCGTATTCCCTGCGCCACC
ACCTTGGAATGACAACCCCCTCCCTCAACCTCTCGCGTACTTTACAGCCGATCTTGGAAC
CAAAAT
Restriction Sites NotI-NotI     
ACCN NM_024624
Insert Size 5000 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_024624.3, NP_078900.1
RefSeq Size 5151 bp
RefSeq ORF 3276 bp
Locus ID 79677
UniProt ID Q96SB8
Domains SMC_C
Gene Summary Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome (PubMed:26983541).[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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