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EMP2 (NM_001424) Human Untagged Clone
CAT＃: SC108082
EMP2 (untagged)-Human epithelial membrane protein 2 (EMP2)
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | XMP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108082 sequence for NM_001424 edited (data generated by NextGen Sequencing)
ATGTTGGTGCTTCTTGCTTTCATCATCGCCTTCCACATCACCTCTGCAGCCTTGCTGTTC ATTGCCACCGTCGACAATGCCTGGTGGGTAGGAGATGAGTTTTTTGCAGATGTCTGGAGA ATATGTACCAACAACACGAATTGCACAGTCATCAATGACAGCTTTCAAGAGTACTCCACG CTGCAGGCGGTCCAGGCCACCATGATCCTCTCCACCATTCTCTGCTGCATCGCCTTCTTC ATCTTCGTGCTCCAGCTCTTCCGCCTGAAGCAGGGAGAGAGGTTTGTCCTAACCTCCATC ATCCAGCTAATGTCATGTCTGTGTGTCATGATTGCGGCCTCCATTTATACAGACAGGCGT GAAGACATTCACGACAAAAACGCGAAATTCTATCCCGTGACCAGAGAAGGCAGCTACGGC TACTCCTACATCCTGGCGTGGGTGGCCTTCGCCTGCACCTTCATCAGCGGCATGATGTAC CTGATACTGAGGAAGCGCAAATAG Clone variation with respect to NM_001424.4 >OriGene 5' read for NM_001424 unedited
TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGCCTCGACTCGCC CTGCCCTGTGAAAAGTTGGTGCTTCTTGCTTTCATCATCGCCTTCCACATCACCTCTGCA GCCTTGCTGTTCATTGCCACCGTCGACAATGCCTGGTGGGTAGGAGATGAGTTTTTTGCA GATGTCTGGAGAATATGTACCAACAACACGAATTGCACAGTCATCAATGACAGCTTTCAA GAGTACTCCACGCTGCAGGCGGTCCAGGCCACCATGATCCTCTCCACCATTCTCTGCTGC ATCGCCTTCTTCATCTTCGTGCTCCAGCTCTTCCGCCTGAAGCAGGGAGAGAGGTTTGTC CTAACCTCCATCATCCAGCTAATGTCATGTCTGTGTGTCATGATTGCGGCCTCCATTTAT ACAGACAGGCGTGAAGACATTCACGACAAAAACGCGAAATTCTATCCCGTGACCAGAGAA GGCAGCTACGGCTACTCCTACATCCTGGCGTGGGTGGCCTTCGCCTGCACCTTCATCAGC GGCATGATGTACCTGATACTGAGGAAGCGCAAATAGAGTTCCGGAGCTGGGTTGCTTCTG CTGCAGTACAGAATCCACATTCAGATAACCATTTTGTATATAATCATTATTTTTTTGAGG TTNTTCTAGCAAACGTNATTGTTTCCTTTTAAAGCCAAAAAAAAAAAAANAAANNNANNA NAANAAAAAANANAAAAAAAANNAAAANAAAAAAAAAAANNAAAAAAAAAAAAAAANACC CTCATTTTAATTGCCGCCGGTCTATAACTTTTTCTTGACAATCCCCGGGTGGATTCCTGG GACCCTCCCAGGCCTTCTGCCCCGTGGAAGTGCCCTTCACGGCCCCACCTGGCTAAAAAA ATAGTGCTCATTTGCGACAAGGGCTATN >OriGene 3' read for NM_001424 unedited
TTTTTTTTTTNNNNNTTNNNTTTTTATTTATTTTTTTTTGAAATTCTTTAGGATAACATA CGTTTGCTAGNAAAACCTCAAAAATAATGATTTTACAAAAGGTTCATCTGATGTGGATTC TGTACTGCAGCAGAAGCAACCCAGCTCCGGAACTCTATTTGCGCTTCCTCAGTATCAGGT ACATCATGCCGCTGATGAAGGTGCAGGCGAAGGCCACCCACGCCAGGATGTAGGAGTAGC CGTAGCTGCCTTCTCTGGTCACGGGATAGAATTTCGCGTTTTTGTCGTGAATGTCTTCAC GCCTGTCTGTATAAATGGAGGCCGCATTCATGACACACAGACATGACATTACCTGGATGA TGGAGGTTAGGACAAACCTCTCTCCCTGCTTCAGGCGGAAGAGCTGGAGCACGAAGATGA AGAAGGCGATGCAGCAGATAATGGTGGAGAGGATCATGGTGGCCTGGACCGCCTGCAGCG TGGAGTACTCTTGAAAGCTGTCATTGATGACTGTGCAATTCGTGTTGATGGTACATATTC TCCAGACATCTGCAAAAAACTCATCTCCTACCCACCCAGCATTGTCGACGGTGGCAATGA ACAGCAAGGCTTGACAGGTGATGTGGAAGGCGATGATGAAAGCCAGACACCCCAACCTTT TCACAGTGCACGGCCAAGCCAGGCGACTTCGTGCCCGAATTTCCCGGCCGCCCTATAGTG AGCCCGGATTACAAAAATTCTGGCGGGTCCACTAAACGAAGCTCTGGTTTATTAAACCTT CCCACCGTACACGCCCTACCGCCCAATTTGGGTCCACGGGGCCGGGGTATTTACCACATT TTTGGAAAGTTCCCGTTGTTTCTTGGGGGCCCAAACAAAACTCCCCTATGCCCGTTAATT GGGCGTGGCAGACTTTGAACATCCCCGGCGAGTANACACGCTTTTGTCACGCCCCATCTG CCGGACCTCGCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001424 |
| Insert Size | 660 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001424.3, NP_001415.1 |
| RefSeq Size | 1484 bp |
| RefSeq ORF | 504 bp |
| Locus ID | 2013 |
| UniProt ID | P54851 |
| Domains | PMP22_Claudin |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a tetraspan protein of the PMP22/EMP family. The encoded protein regulates cell membrane composition. It has been associated with various functions including endocytosis, cell signaling, cell proliferation, cell migration, cell adhesion, cell death, cholesterol homeostasis, urinary albumin excretion, and embryo implantation. It is known to negatively regulate caveolin-1, a scaffolding protein which is the main component of the caveolae plasma membrane invaginations found in most cell types. Through activation of PTK2 it positively regulates vascular endothelial growth factor A. It also modulates the function of specific integrin isomers in the plasma membrane. Up-regulation of this gene has been linked to cancer progression in multiple different tissues. Mutations in this gene have been associated with nephrotic syndrome type 10 (NPHS10). [provided by RefSeq, Mar 2015] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201995 | EMP2 (Myc-DDK-tagged)-Human epithelial membrane protein 2 (EMP2) |
CNY 2,400.00 |
|
| RC201995L1 | Lenti ORF clone of Human epithelial membrane protein 2 (EMP2), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201995L2 | Lenti ORF clone of Human epithelial membrane protein 2 (EMP2), mGFP tagged |
CNY 5,890.00 |
|
| RC201995L3 | Lenti ORF clone of Human epithelial membrane protein 2 (EMP2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201995L4 | Lenti ORF clone of Human epithelial membrane protein 2 (EMP2), mGFP tagged |
CNY 4,800.00 |
|
| RG201995 | EMP2 (tGFP-tagged) - Human epithelial membrane protein 2 (EMP2) |
CNY 4,000.00 |
