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SMCR7L (MIEF1) (NM_019008) Human Untagged Clone
CAT＃: SC108065
SMCR7L (untagged)-Human Smith-Magenis syndrome chromosome region, candidate 7-like (SMCR7L)
CN¥ 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AltMIEF1; dJ1104E15.3; HSU79252; MID51; MIEF1-MP; SMCR7L |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_019008, the custom clone sequence may differ by one or more nucleotides
ATGGCAGGCGCTGGTGAGCGCAAAGGCAAGAAGGATGACAATGGCATTGGCACGGCCATTGACTTTGTGC TCTCCAATGCCCGGCTGGTGCTGGGGGTGGGTGGAGCGGCCATGCTGGGCATCGCCACGCTGGCAGTTAA GCGGATGTACGATCGGGCGATCAGTGCCCCTACCAGCCCCACCCGCCTGAGCCATTCGGGGAAAAGGAGC TGGGAAGAACCCAACTGGATGGGCTCCCCACGACTGCTGAACAGGGACATGAAGACGGGCCTGAGCCGGT CCTTGCAGACCCTTCCCACAGACTCCTCCACCTTCGACACAGATACATTCTGCCCGCCCCGGCCCAAGCC AGTGGCCAGGAAGGGCCAGGTAGACTTGAAGAAGTCACGACTCCGCATGTCCCTGCAGGAGAAACTTCTT ACTTACTACCGGAACCGGGCAGCCATCCCTGCTGGAGAGCAGGCTCGGGCCAAGCAAGCTGCTGTGGACA TATGTGCCGAGCTCCGGAGCTTCCTGCGGGCCAAGTTGCCTGACATGCCGCTTCGGGACATGTACTTGAG TGGCAGCCTCTACGATGACCTGCAGGTGGTGACAGCTGACCACATCCAACTCATTGTGCCCCTTGTGCTG GAGCAGAACCTGTGGTCATGTATTCCTGGTGAAGACACCATCATGAATGTCCCTGGCTTCTTCCTGGTGC GTCGTGAGAATCCAGAGTACTTTCCTCGTGGGAGCAGTTACTGGGACCGCTGTGTAGTAGGGGGCTACCT CTCTCCAAAGACAGTCGCAGATACATTTGAGAAGGTAGTGGCTGGCTCCATCAATTGGCCAGCCATAGGG TCCCTCTTGGACTATGTGATCCGCCCGGCCCCACCCCCAGAAGCCCTCACACTGGAGGTGCAGTATGAGC GTGACAAACATCTCTTCATTGACTTCCTGCCATCAGTGACCCTCGGTGACACAGTCTTGGTGGCCAAACC ACACCGGCTAGCCCAGTATGACAACCTGTGGCGGCTGAGCCTGCGTCCCGCGGAGACGGCACGCCTGCGG GCTCTGGACCAGGCTGACTCGGGCTGCCGATCTCTGTGCCTCAAGATCCTCAAGGCCATATGCAAGTCCA CCCCGGCTCTGGGCCACCTCACTGCCAGCCAGCTAACCAATGTCATCCTCCACTTGGCCCAGGAGGAGGC TGACTGGTCTCCGGATATGCTGGCCGACCGTTTCCTGCAGGCCTTGAGGGGACTTATCAGCTACTTAGAG GCTGGAGTCCTGCCCAGTGCCCTAAACCCCAAGGTGAACTTATTTGCAGAGCTCACCCCTGAAGAAATAG ACGAATTAGGATACACTCTGTATTGCTCATTGTCTGAGCCAGAGGTGCTGCTGCAGACGTAG >OriGene 5' read for NM_019008 unedited
GGGTTTTCCGACTTAGGTTAACTCNACTCTCCTTTCATGGNNCGGCCGCGCAATTCGGCA CGAGGCTAGAGGACGCTGAGGCCCTTCTCCACGGCAAATTGGGGAGGATCATTTAGGATC CTCCAAGGGGAAAGAGGACAAAGGTGCCTTCTGTAGACACTCCTGCTCTCTTCCATCCCC ATCTTACAGATGTATTAAGAAGCCTCAGATGAGCAATGGCAGGCGCTGGTGAGCGCAAAG GCAAGAAGGATGACAATGGCATTGGCACGGCCATTGACTTTGTGCTCTCCAATGCCCGGC TGGTGCTGGGGGTGGGTGGAGCGGCCATGCTGGGCATCGCCACGCTGGCAGTTAAGCGGA TGTACGATCGGGCGATCAGTGCCCCTACCAGCCCCACCCGCCTGAGCCATTCGGGGAAAA GGAGCTGGGAAGAACCCAACTGGATGGGCTCCCCACGACTGCTGAACAGGGACATGAAGA CGGGCCTGAGCCGGTCCTTGCAGACCCTTCCCACAGACTCCTCCACCTTCGACACAGGAG AAACTTCTTACTTACTACCGGAACCCGGCAGCCCTCCCTGCTGGAGAGCACGCTCGGGCC AAGCAAGCTGCTGTGGACATTTTGTGCCGAGCTCCGGAAGCTTCTGCGGGCCAAGTTGCC CTGACTTGCCGCTTCGGGACATGTACTTGAGTGGCAGCCTCTACCATGACCTGCAAGTGG TGACAGCTGACCACTTCCACTCATTGTGCCCCCTGGGCTGGACCAAACCCCGTGGGCATG TATTCCTGGGGAGACCCCTTCTTGATGTCCCTGGCCTCCTTCTGAACGCGTGGGAAAATA CCAAATACCTTCCCTCGGGGGAACAGTTACCGGGACCCGTGGTGGAACAAGGGGCCTACC CTCTTTCAAAGACAGTGG >OriGene 3' read for NM_019008 unedited
TTACCGCGGCCGCATTCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAACTCTCATTTGATT CTGACCAACAGAACAGGGTAGATGAGCTCTCTCAAGATTCTCAGCTTTATGTTTTTTGTT CCCTCTCAATACCTTTATGCAAATGAAACTGAAACCACCATAAGAAATCCTTGTTAAGGG GAAAAGAGGCAAAAAGACCTCTAAATATAGTCAAGGTTAACCCTAGTTCTCAATTTCCTA ATCTGTGACAAAAGAGGGGCAGGAATCTCTACCCTAAATTGATGTTGAGGTATCGATGCT AAAGAGTCATTTCCTGTTACTATCGTTGGGAAGGAATGAGACAGCTGCAGAGAGCTTCAC CAGAACCTCAATGATGGAGAGGTAGTCATTGAAAAAATAAGACAACTTGACGGAAGGAAA ACAAAATACTGAATGGGCAGATGAGAAACAGAATTATCATCAGAGTCTTGCTACAAACAG GGAAAAACACAAACCAAGATGACACACGGACATGGTAGATTAAACATTCCCTCCCACCTT CAGGATACATTTACATTGCAATAAATACTGCAATCTCAGCACCGGCAAACAAGGAGGAAT GTACGAAATGCCCACCTCCTCCCCTCTGTCTTATCTGTGTGCCTCTTTTCCTTGGGAGCA CCGATCCCCCCAAGCGCTTGGGTGACAAACAGGACAGGTGGCACACGTCCCCAGCTTGCT CACTTTCCCCCTTGGCCCTGTCCGGAACGCCTCACAAACACCGCTTCTTCCTTCCTATGT TAACACCCCCACGACCACGGCTGGCTTTTCGCCCTGTCCTCCCCCCAGGCATTTCCTCAA CAACACGGTTGCCTTGAACTAACCCGGTCCCCTCCCCATCTTGACCGAACTTTCCCCACA CTCCCACAATCCCCCCACCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_019008 |
| Insert Size | 3670 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_019008.4, NP_061881.2 |
| RefSeq Size | 5730 bp |
| RefSeq ORF | 1392 bp |
| Locus ID | 54471 |
| UniProt ID | Q9NQG6 |
| Protein Families | Transmembrane |
| Gene Summary | Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents a predominant transcript, which encodes a 463aa protein (isoform 1). |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203568 | SMCR7L (Myc-DDK-tagged)-Human Smith-Magenis syndrome chromosome region, candidate 7-like (SMCR7L) |
CN¥ 3,656.00 |
|
| RC203568L3 | Lenti ORF clone of Human Smith-Magenis syndrome chromosome region, candidate 7-like (SMCR7L), Myc-DDK-tagged |
CN¥ 5,890.00 |
|
| RC203568L4 | Lenti ORF clone of Human Smith-Magenis syndrome chromosome region, candidate 7-like (SMCR7L), mGFP tagged |
CN¥ 5,890.00 |
|
| RG203568 | SMCR7L (tGFP-tagged) - Human Smith-Magenis syndrome chromosome region, candidate 7-like (SMCR7L) |
CN¥ 5,256.00 |
