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PAK5 (NM_177990) Human Untagged Clone
CAT＃: SC107077
PAK7 (untagged)-Human p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PAK7 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_177990 edited
ATGTTTGGGAAGAAAAAGAAAAAGATTGAAATATCTGGCCCGTCCAACTTTGAACACAGG GTTCATACTGGGTTTGATCCACAAGAGCAGAAGTTTACCGGCCTTCCCCAGCAGTGGCAC AGCCTGTTAGCAGATACGGCCAACAGGCCAAAGCCTATGGTGGACCCTTCATGCATCACA CCCATCCAGCTGGCTCCTATGAAGACAATCGTTAGAGGAAACAAACCCTGCAAGGAAACC TCCATCAACGGCCTGCTAGAGGATTTTGACAACATCTCGGTGACTCGCTCCAACTCCCTA AGGAAAGAAAGCCCACCCACCCCAGATCAGGGAGCCTCCAGCCACGGTCCAGGCCACGCG GAAGAAAATGGCTTCATCACCTTCTCCCAGTATTCCAGCGAATCCGATACTACTGCTGAC TACACGACCGAAAAGTACAGGGAGAAGAGTCTCTATGGAGATGATCTGGATCCGTATTAT AGAGGCAGCCACGCAGCCAAGCAAAATGGGCACGTAATGAAAATGAAGCACGGGGAGGCC TACTATTCTGAGGTGAAGCCTTTGAAATCCGATTTTGCCAGATTTTCTGCCGATTATCAC TCACATTTGGACTCACTGAGCAAACCAAGTGAATACAGTGACCTCAAGTGGGAGTATCAG AGAGCCTCGAGTAGCTCCCCTCTGGATTATTCATTCCAATTCACACCTTCTAGAACTGCA GGGACCAGCGGGTGCTCCAAGGAGAGCCTGGCGTACAGTGAAAGTGAATGGGGACCCAGC CTGGATGACTATGACAGGAGGCCAAAGTCTTCGTACCTGAATCAGACAAGCCCTCAGCCC ACCATGCGGCAGAGGTCCAGGTCAGGCTCGGGACTCCAGGAACCGATGATGCCATTTGGA GCAAGTGCATTTAAAACCCATCCCCAAGGACACTCCTACAACTCCTACACCTACCCTCGC TTGTCCGAGCCCACAATGTGCATTCCAAAGGTGGATTACGATCGAGCACAGATGGTCCTC AGCCCTCCACTGTCAGGGTCTGACACCTACCCCAGGGGCCCTGCCAAACTACCTCAAAGT CAAAGCAAATCGGGCTATTCCTCAAGCAGTCACCAGTACCCGTCTGGGTACCACAAAGCC ACCTTGTACCATCACCCCTCCCTGCAGAGCAGTTCGCAGTACATCTCCACGGCTTCCTAC CTGAGCTCCCTCAGCCTCTCATCCAGCACCTACCCGCCGCCCAGCTGGGGCTCCTCCTCC GACCAGCAGCCCTCCAGGGTGTCCCATGAACAGTTTCGGGCGGCCCTGCAGCTGGTGGTC AGCCCAGGAGACCCCAGGGAATACTTGGCCAACTTTATCAAAATCGGGGAAGGCTCAACC GGCATCGTATGCATCGCCACCGAGAAACACACAGGGAAACAAGTTGCAGTGAAGAAAATG GACCTCCGGAAGCAACAGAGACGAGAATTGCTTTTCAATGAGGTCGTGATCATGCGGGAT TACCACCATGACAATGTGGTTGACATGTACAACAGCTACCTTGTCGGCGATGAGCTCTGG GTGGTCATGGAGTTTCTAGAAGGTGGTGCCTTGACAGACATTGTGACTCACACCAGAATG AATGAAGAACAGATAGCTACTGTCTGCCTGTCAGTTCTGAGAGCTCTCTCCTACCTTCAT AACCAAGGAGTGATTCACAGGGACATAAAAAGTGACTCCATCCTCCTGACAAGCGATGGC CGGATAAAGTTGTCTGATTTTGGTTTCTGTGCTCAAGTTTCCAAAGAGGTGCCGAAGAGG AAATCATTGGTTGGCACTCCCTACTGGATGGCCCCTGAGGTGATTTCTAGGCTACCTTAT GGGACAGAGGTGGACATCTGGTCCCTCGGGATCATGGTGATAGAAATGATTGATGGCGAG CCCCCCTACTTCAATGAGCCTCCCCTCCAGGCGATGCGGAGGATCCGGGACAGTTTACCT CCAAGAGTGAAGGACCTACACAAGGTTTCTTCAGTGCTCCGGGGATTCCTAGACTTGATG TTGGTGAGGGAGCCCTCTCAGAGAGCAACAGCCCAGGAACTCCTCGGACATCCATTCTTA AAACTAGCAGGTCCACCGTCTTGCATCGTCCCCCTCATGAGACAATACAGGCATCACTGA >OriGene 5' read for NM_177990 unedited
AATCCCGCCCGTTGCCGCATTGGGCGGTAGGCGTGTACCGTGGGAGGTCTATATAAGCAG AGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAAT TCGGCACGAGGCCCCCTTGCCCCTACCCAGCCAGTAGTAGTTCCCCAGCGTGCGCCCGGG GAGACCGGGAACATGGCGCTGGGAGCGCTGTAGCATCTGAGAAGGGGCTGAGGCACCGCC GCTTCGCTGACAGCCGGCCACCAGAAATACACTGTGGTGAAATGCTTCCACCTCTTGCTA AAATGAACACTGAGAAAAAATGAAGAAGACTGACAAGCACCAGCGAAAAGTTGCAAAATA CAAATAGCCACACTCCTCTGGAGTCTTTAATTCATCCACAGCCATCATATAAAGGTTTTG GCATCATGTTTGGGAAGAAAAAGAAAAAGATTGAAATATCTGGCCCGTCCAACTTTGAAC ACAGGGTTCATACTGGGTTTGATCCACAAGAGCAGAAGTTTACCGGCCTTCCCCAGCAGT GGCACAGCCTGTTAGCAGATACCGTCAACATGCCAAAGCCTATGGTGGACCCTTCATGCA TCACACCCATCCAGCTGGCTCCTATGAAGACAATCGTTAGAGGAAACAAACCCTGCAAGG AAACCTCCATGAACGGCCTGCTAGAGGATTTTGACAACATCTTAGTGACTCGCTGCAACT CCATAGGTAAGAAAGCCCACCCACCCCACATCAGGGAGCCTCTCGCCACGGTCCAGGCCA CGCCGGAACATATGGGCTTCATACCTTCTCCCAGTATTCCAGCGATCCCATACTACTGGT GACTACACGACCGAATATGCCGGGAGAACATCCTCTTTGAAATGAACTGCATCCGTTTAT AGACGCATCCGCGCAGCCAGGCAATGTGCCCTGTAGT >OriGene 3' read for NM_177990 unedited
ATTAGATTTCTTTCATATANAAAATCTACTGTTACCCTGCATGTGGCTAGGATATATCAT AACGGAGTTTGTACTGAGTCCTTCTGATTTGCTGGATGAAGGGCTGAAAAATATAATAAT GACTTATTAAAGCCGTGCTCCAAGTGACCACACCGGCTGTCAGTGGAGAGATGCCTGTTT AAGACACAAGAAGATGCCCTGGTCTGTTGAACCCTGCCGGTCATCACGCTGTCCCACCAA TTGGCTGGTCTAGAATGCACAGGCCTTTTGCATGTTCTGTGTTTCCTTTTGTTCTCCTGA ATTATTCTCATGTCCTCATCTAGCTTTGCCACCTACACGAATCCTCTGCTCAGTGATGCC TGTATTGTCTCATGAGGGGGACGATGCAAGACGGTGGACCTGCTAGTTTTAAGAATGGAT GTCCGAGGAGTTCCTGGGCTGTTGCTCTCTGAGAGGGCTCCCTCACCAACATCAAGTCTA GGAATCCCCGGAGCACTGAAGAAACCTTGTGTAGGTCCTTCACTCTTGGAGGTAAACTGT CCCGGATCCTCCGCATCGCCTGGAGGGGAGGCTCATTGAAGTAGGGGGGCTCGCCATCAA TCATTTCTATCACCATGATCCCGAGGGACCAGATGTCCACCTCTGTCCCATAAGGTAGCC TAGAAATCACCTCAGGGGCCATCCAGTANGGAGTGCCAACCAATGATTTCCCTCTTCGCA CCTCTTTGGGAACTTGAGCACAGAAACCAAATCAGACACTTTTTCCGGCCATCGCTTGGT CAGGAGATGGAGTCACTTTTTATGTCCCTGTGGATCACTCCCTTGTTATGAAGGTAGGGA GAGAGCTCTTAGAACTGACAGGCAGACAGGAGCTATCTGGTCTTCTTCATTCTGGTGTGA GTCACATGTCTGTCAGGCACCCACTTCTAAAACTCCTGAACCCCAGACTCATGCCGAAAG TAGCTGTGTCCATT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_177990 |
| Insert Size | 4840 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_177990.1, NP_817127.1 |
| RefSeq Size | 4506 bp |
| RefSeq ORF | 2160 bp |
| Locus ID | 57144 |
| UniProt ID | Q9P286 |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Axon guidance, ErbB signaling pathway, Focal adhesion, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an internal 5' UTR exon, as compared to variant 1. Both variants encode the same protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214173 | PAK7 (Myc-DDK-tagged)-Human p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2 |
CNY 5,264.00 |
|
| RC214173L1 | Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2, Myc-DDK-tagged |
CNY 7,664.00 |
|
| RC214173L2 | Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC214173L3 | Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC214173L4 | Lenti ORF clone of Human p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG214173 | PAK7 (tGFP-tagged) - Human p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2 |
CNY 6,864.00 |
|
| SC323605 | PAK7 (untagged)-Kinase deficient mutant (K478M) of Human p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7), transcript variant 2 |
CNY 5,272.00 |
