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PDE4 (PDE4B) (NM_002600) Human Untagged Clone
CAT＃: SC106296
PDE4B (untagged)-Human phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a
CNY 5,400.00
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DPDE4; PDEIVB |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC106296 sequence for NM_002600 edited (data generated by NextGen Sequencing)
ATGAAGAAAAGCAGGAGTGTGATGACGGTGATGGCTGATGATAATGTTAAAGATTATTTT GAATGTAGCTTGAGTAAATCCTACAGTTCTTCCAGTAACACACTTGGGATCGACCTCTGG AGAGGGAGAAGGTGTTGCTCAGGAAACTTACAGTTACCACCACTGTCTCAAAGACAGAGT GAAAGGGCAAGGACTCCTGAGGGAGATGGTATTTCCAGGCCGACCACACTGCCTTTGACA ACGCTTCCAAGCATTGCTATTACAACTGTAAGCCAGGAGTGCTTTGATGTGGAAAATGGC CCTTCCCCAGGTCGGAGTCCACTGGATCCCCAGGCCAGCTCTTCCGCTGGGCTGGTACTT CACGCCACCTTTCCTGGGCACAGCCAGCGCAGAGAGTCATTTCTCTACAGATCAGACAGC GACTATGACTTGTCACCAAAGGCGATGTCGAGAAACTCTTCTCTTCCAAGCGAGCAACAC GGCGATGACTTGATTGTAACTCCTTTTGCCCAGGTCCTTGCCAGCTTGCGAAGTGTGAGA AACAACTTCACTATACTGACAAACCTTCATGGTACATCTAACAAGAGGTCCCCAGCTGCT AGTCAGCCTCCTGTCTCCAGAGTCAACCCACAAGAAGAATCTTATCAAAAATTAGCAATG GAAACGCTGGAGGAATTAGACTGGTGTTTAGACCAGCTAGAGACCATACAGACCTACCGG TCTGTCAGTGAGATGGCTTCTAACAAGTTCAAAAGAATGCTGAACCGGGAGCTGACACAC CTCTCAGAGATGAGCCGATCAGGGAACCAGGTGTCTGAATACATTTCAAATACTTTCTTA GACAAGCAGAATGATGTGGAGATCCCATCTCCTACCCAGAAAGACAGGGAGAAAAAGAAA AAGCAGCAGCTCATGACCCAGATAAGTGGAGTGAAGAAATTAATGCATAGTTCAAGCCTA AACAATACAAGCATCTCACGCTTTGGAGTCAACACTGAAAATGAAGATCACCTGGCCAAG GAGCTGGAAGACCTGAACAAATGGGGTCTTAACATCTTTAATGTGGCTGGATATTCTCAC AATAGACCCCTAACATGCATCATGTATGCTATATTCCAGGAAAGAGACCTCCTAAAGACA TTCAGAATCTCATCTGACACATTTATAACCTACATGATGACTTTAGAAGACCATTACCAT TCTGACGTGGCATATCACAACAGCCTGCACGCTGCTGATGTAGCCCAGTCGACCCATGTT CTCCTTTCTACACCAGCATTAGACGCTGTCTTCACAGATTTGGAGATCCTGGCTGCCATT TTTGCAGCTGCCATCCATGACGTTGATCATCCTGGAGTCTCCAATCAGTTTCTCATCAAC ACAAATTCAGAACTTGCTTTGATGTATAATGATGAATCTGTGTTGGAAAATCATCACCTT GCTGTGGGTTTCAAACTGCTGCAAGAAGAACACTGTGACATCTTCATGAATCTCACCAAG AAGCAGCGTCAGACACTCAGGAAGATGGTTATTGACATGGTGTTAGCAACTGATATGTCT AAACATATGAGCCTGCTGGCAGACCTGAAGACAATGGTAGAAACGAAGAAAGTTACAAGT TCAGGCGTTCTTCTCCTAGACAACTATACCGATCGCATTCAGGTCCTTCGCAACATGGTA CACTGTGCAGACCTGAGCAACCCCACCAAGTCCTTGGAATTGTATCGGCAATGGACAGAC CGCATCATGGAGGAATTTTTCCAGCAGGGAGACAAAGAGCGGGAGAGGGGAATGGAAATT AGCCCAATGTGTGATAAACACACAGCTTCTGTGGAAAAATCCCAGGTTGGTTTCATCGAC TACATTGTCCATCCATTGTGGGAGACATGGGCAGATTTGGTACAGCCTGATGCTCAGGAC ATTCTCGATACCTTAGAAGATAACAGGAACTGGTATCAGAGCATGATACCTCAAAGTCCC TCACCACCACTGGACGAGCAGAACAGGGACTGCCAGGGTCTGATGGAGAAGTTTCAGTTT GAACTGACTCTCGATGAGGAAGATTCTGAAGGACCTGAGAAGGAGGGAGAGGGACACAGC TATTTCAGCAGCACAAAGACGCTTTGTGTGATTGATCCAGAAAACAGAGATTCCCTGGGA GAGACTGACATAGACATTGCAACAGAAGACAAGTCCCCCGTGGATACATAA Clone variation with respect to NM_002600.3 >OriGene 5' read for NM_002600 unedited
TCAGCAATTTGTAATACGACCTCACTATAGGGCGGCCGCGAATTCGCACGAGGAAAAATG TCAGCAAACTGCATTGAATAACAGACATCCTAAGAGGGGATATTTTCCACCTCTATAATG AAGAAAAGCAGGAGTGTGATGACGGTGATGGCTGATGATAATGTTAAAGATTATTTTGAA TGTAGCTTGAGTAAATCCTACAGTTCTTCCAGTAACACACTTGGGATCGACCTCTGGAGA GGGAGAAGGTGTTGCTCAGGAAACTTACAGTTACCACCACTGTCTCAAAGACAGAGTGAA AGGGCAAGGACTCCTGAGGGAGATGGTATTTCCAGGCCGACCACACTGCCTTTGACAACG CTTCCAAGCATTGCTATTACAACTGTAAGCCAGGAGTGCTTTGATGTGGAAAATGGCCCT TCCCCAGGTCGGAGTCCACTGGATCCCCAGGCCAGCTCTTCCGCTGGGCTGGTACTTCAC GCCACCTTTCCTGGGCACAGCCAGCGCAGAGAGTCATTTCTCTACAGATCAGACAGCGAC TATGACTTGTCACCAAAGGCGATGTCGAGAAACTCTTCTCTTCCAAGCGAGCAACACGGC GATGACTTGATTGTAACTCCTTTTGCCCAGGTCCTTGCCAGCTTGCGAAGTGTGAGAAAC AACTTCACTATACTGACAAACCTTCATGGTACATCTAACAAGAGGTCCCCAGCTGCTAGT CAGCCTCCTGTCTCCAGAGTCAACCCACAAGAAAATCTTATCAAAAATTAGCAATGGAAA CGCTGGAGGAATTAGACTGGGTGTTAGACCAGCTAGAGACCATACAGACCTACCCGTCTG TCAGTGAGATGGCTTCTAAACAGNTCAAAGAATGCTGAACCGGNAGCTGACACCCTCTCA AAGAGAGCCGATCAGGNAACCAGTGTCTGATACT >OriGene 3' genomic read for NM_002600 unedited
NNNNCCCTACTGTGNNACCGCGGCCTTATNCNANGATCGNATTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAACATGCTTTTCTTTATTCACCTCATAAAA AAGTCTCTTTAGAATGCATTTGAACACAATATATAATAATAATACTATAACATACATTGG GAGAAACATTTGAAAATGATAAAATGTCCACCTGAAACAATGCAGTGTTCATAAACATAC ATTGGTCATGCACATTTGTGCCATTTTCTGTAATTACTGAGTCACAATGCTGAACTGAAA GCATGAAACATATTTTACAAACTGAAACTGACATCAGTAAAAGGCCTAACAAGTGTTATC AAAAAAGGCTTCACATTTGCGTAATTTGCTACATCAGTTCACATTTTATTATAAAAATTC ACATTGGTTTATTGGTTTCTTTTGGAAAGAACTGGAACATGACATTCCTGCTTAATGGCA GGCAGGAGGCTACCTCTTCAAAGTCAGTAGTTCGGGAGCATTCAAAAAAATCATCTGTGA GCAAATGTAGTGTTTCCTTTTGAACCAAAGCCACAATGATAGTAGGATCCAGTTATAACC CAACTCATGCCCACATAAATTTGGATAGAACCTGGGTAAAAACTACATCCCATTGCCCCC TGCCCCTATCAAGCTTTACAAAAGTAAAAGCTCAGTATAAACCATTTAGTATCTAAGGTG AGAATATTGTTTCCAAAACTGGTTCATAAAGGGGGTGGGCAAAAATAGCAACTCAGGCAC GGAAAGGGCAGACCCTTTGAACAAAGCCCCCCCTGTTCTTTCTGGCAAGGGGGGCCTATG TCCTTTCCTAAGGACGTTGGGGTTAATAAAAN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002600 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002600.3, NP_002591.2 |
| RefSeq Size | 4264 bp |
| RefSeq ORF | 2211 bp |
| Locus ID | 5142 |
| UniProt ID | Q07343 |
| Domains | PDEase |
| Protein Families | Druggable Genome |
| Protein Pathways | Progesterone-mediated oocyte maturation, Purine metabolism |
| Gene Summary | This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] Transcript Variant: This variant (a) encodes the longest isoform (1, also referred to as PDE4B1 or Tm72). Both variants a and d encode the same isoform. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211956 | PDE4B (Myc-DDK-tagged)-Human phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a |
CNY 5,392.00 |
|
| RC211956L1 | Lenti ORF clone of Human phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a, Myc-DDK-tagged |
CNY 7,792.00 |
|
| RC211956L2 | Lenti ORF clone of Human phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a, mGFP tagged |
CNY 5,890.00 |
|
| RC211956L3 | Lenti ORF clone of Human phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC211956L4 | Lenti ORF clone of Human phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a, mGFP tagged |
CNY 5,890.00 |
|
| RG211956 | PDE4B (tGFP-tagged) - Human phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a |
CNY 6,992.00 |
