Scramblase 1 (PLSCR1) (BC017901) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	MMTRA1B; phospholipid scramblase 1
Vector	pCMV6-XL4
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for BC017901, the custom clone sequence may differ by one or more nucleotides ATGGACAAACAAAACTCACAGATGAATGCTTCTCACCCGGAAACAAACTTGCCAGTTGGGTATCCTCCTC AGTATCCACCGACAGCATTCCAAGGACCTCCAGGATATAGTGGCTACCCTGGGCCCCAGGTCAGCTACCC ACCCCCACCAGCCGGCCATTCAGGTCCTGGCCCAGCTGGCTTTCCTGTCCCAAATCAGCCAGTGTATAAT CAGCCAGTATATAATCAGCCAGTTGGAGCTGCAGGGGTACCATGGATGCCAGCGCCACAGCCTCCATTAA ACTGTCCACCTGGATTAGAATATTTAAGTCAGGTAATTTCAAAGACACAAAATACTCATAAAAAACAGAA CTGTGCTTCCAGCTTGCTTAACCAGATTAGCAAATGA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC017901 unedited GTCATCATTTGTATACGACTCATATAGGGCGGCCGCGATTCGGCACGAGGCGCAGCAGCT GTGCCCGGCAGTCTAGAGGCGCAGAAGAGGAAGCCATCGCCTGGCCCCGGCTCTCTGGAC CTTGTCTCGCTCGGGAGCGGAAACAGCGGCAGCCAGAGAACTGTTTTAATCATGGACAAA CAAAACTCACAGATGAATGCTTCTCACCCGGAAACAAACTTGCCAGTTGGGTATCCTCCT CAGTATCCACCGACAGCATTCCAAGGACCTCCAGGATATAGTGGCTACCCTGGGCCCCAG GTCAGCTACCCACCCCCACCAGCCGGCCATTCAGGTCCTGGCCCAGCTGGCTTTCCTGTC CCAAATCAGCCAGTGTATAATCAGCCAGTATATAATCAGCCAGTTGGAGCTGCAGGGGTA CCATGGATGCCAGCGCCACAGCCTCCATTAAACTGTCCACCTGGATTAGAATATTTAAGT CAGATAGATCAGATACTGATTCATCAGCAAATTGAACTTCTGGAAGTTTTAACAGGTTTT GAAACTAATAACAAATATGAAATTAAGAACAGCTTTGGACAGAGGGTTTACTTTGCAGCG GAAGATACTGATTGCTGTACCCGAAATTGCTGTGGGCCATCTAGACCTTTTACCTTGAGG ATTATTGATAATATGGGTCAAGAAGTCATAACTCTGGAGAGACCACTAAGATGTAGCAGC TGTTGTTGTCCCTGCTGCCTTCNAGAGGTCTGTGATCAATTACCAGAGCACTNTGTAAAA TAGTTCAGCAAGAATTTCTGCCCTGTCATTGAACCTTTCATCGAACCTAGGCATTATGAT TATTACATTTACATATATTANTTTGCCTTTGTAGATAGAAATCCAGCTCCTNCTGGNTGT ACCATAGNTATGTTATTCAGACTTGGCACCATGTCTACCAAGNTTNACATNANATGA
Restriction Sites	NotI-NotI
ACCN	BC017901
Insert Size	2100 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC017901.1, AAH17901.1
RefSeq Size	1143 bp
RefSeq ORF	1143 bp
Locus ID	5359
Protein Families	Druggable Genome, Stem cell - Pluripotency
Gene Summary	May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.[UniProtKB/Swiss-Prot Function]

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