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ZNRF3 (NM_032173) Human Untagged Clone
CAT＃: SC106136
ZNRF3 (untagged)-Human zinc and ring finger 3 (ZNRF3), transcript variant 2
CNY 1,200.00
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BK747E2.3; RNF203 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>SC106136 representing NM_032173.
Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGTACTTTTGTGGCCTTGGTGTCCGATGGGGCTGGGGGAGAGTGCTCTCCACTGACCCAGCAGCACAC CCATGTGCAGTGCGCCTGCATCTGTGTGGGGGCAGCCACACCCCTTGGCTGCTGCTTCCTTGGGCTGCC TTTCTGGGGGCATGTGACTGGACCTACGAGGTCTGCACTGAGCTCCATTTGAATGATACCTTTCCTATC CCATTTCCCCCACGGAAGCACCGCTTCAGGGTTATTCAGTCCTCTGCCTCATGGCTGAAATTGCTCATC TCGTCTGCAGATGTCTACTATCCTGTCTACCTAATGCACTATTATGTATTGATTCTCCATGAGACAGAG AGAGAGAGAGACTATCAGATAGTTTACACCCAAAGGGTAGGTTTTTGTATATTTTTCCAGCCTTTTTTA TTAAGGGGAAGGGGAGAGTTTAAAAACCCAAACCGTTGTGGTTTTAAGGTGTTTCATTTTTAA >OriGene 5' read for NM_032173 unedited
GGTCACCATTTGTATACGACTCATATGGGCGGCCGCGCAATTCGCACGAGGCTCTGAGGA GCAGTGCAAAACTGCCTCTTTCTTTCTCGTGGCAAATCCCAATGTACACGATTTCAGGTC TCAGACGCCATGCCTCTCCAGCCCACGCCTTTAGGCAGGTGATGGCAGCAGCTAGGAATA GGGTGTACATGATCCACAGCCCTGCGGAGCCAGGTCAAGCCGCTGCTATGAAAGCTCCAG GGTGATGGGGACGATTCTGCCCAGTGTCCTCAGTCTGTCCCCTCAGGTCATGGTCCCAAG TGAAATGACAGAGTTCACAGCCCTGGTCTTGGCTGAGGTCCAGGTCATAGTAAGGGCATG TTCTTGGGGCCCTCGACCTGAACTCTGACCCTCCGGGCAGGGAAGAGGAGGTTGTCCCCT TTGGTTGTCCTGGCTTTGGAGTCCTTTGCAAAAATATTTTGGGCCCCCTGCCACTGGCTG CAGAAATGGCTCGACGGGGTGTGTGGGGACAGACACCCAGAAGGAATGTACTTTTGTGGC CTTGGTGTCCGATGGGGCTGGGGGAGAGTGCTCTCCACTGACCCAGCAGCACACCCATGT GCAGTGCGCCTGCATCTGTGTGGGGGCAGCCACACCCCTTGGCTGCTGCTTCCTTGGGCT GCCTTTCTGGGGGCATGTGACTGGACCTACGAGGTCTGCACTGAGCTCCATTTGCATGAT ACCTTTCCTATCCCATTTCCCCACGGAAGCACCGCTTCAGGGTTTATCAGTCCTCTGCCT CATGCCTGCAATTGCTCATCTCGTCTGCAGATGTCTACTATCCTGTCTACCTAATGCACT ATAATGTATTGATTCTTCCTGAGACCGAGAGAGAGAGAGACTATCCGAAGTTTCACCCCA AGGTAGGGTTTTGATACTTTTCCGCCT >OriGene 3' read for NM_032173 unedited
TTTGGCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGTTTTTTTTTTAA CACATACTTGATAAAATTGTATTTTTTTTTTACAGTCATGTGTACAATTTGTTACAAAAC CATAGAAGACTACAACTTGTTTTAAATCATTTTTGGTCTGCAAATATGTAAAATCTGTGT GCAATTATCATGTATTTACAGGGTCTTGTGTTAGTCATTTTCAATGATTATTCCAACAAT GTCACACTCTCAACATAAGACATGGCTTAAGATAAATATATTAGTAAATAAATATTCTGA GAACATATTTCCATAAATGAAATGTGCTGCTATACATATACAGAATATACATAAGTTGTC TTCTAGCTTTTAAAACATTTTTTAAAAATGGTAATGTTGGAAAAAGAGCCCTTAAACCAT TTTATTACAAAATCTTTACAGCAAGGTCTTTACAAAATCTCTTTTAAGTGCTATGGGAAA AATTAAAAAATTTTAAAATAGTGCCTTGTTAGACCAACACAATAGAAAGAGTTTACCTAA AGAGTAGAAAAAGGCAGTTCTGTTTAAAGAATAATAGTCTCGACTAGTAATTATTTTTTA GACCTCATTTTAAAAGCATTAGTCCTGCACGAACTTCGAGTAGAGACTAGCAGCACATAA GTATGTGAGCAGTGGGACAGAAGGGGCTTTATTTTATAAAAGGGCTTGGATTANGAGGAG ACAGGGAAGGAGCTGAGAGTTAAAGCCAGCTTACTGGGGCTGCATCCATAAAGAGGTACC TTGTTGGTAAACACCCAAACTTCCATTTTTAACTGGTTCTAGAACTCTTCACTGTATATG GCTGCCCTACAACCAGGGCTGGGTCACTTGACCCTGCCCAATGCCACCCCCACTTANAGG GATTGGGGGCAGGGCTCTCAAGGAAATGAAAACTCCTATTTCCATGCTTTNAACCCCCCC ACCTCCAATCCACGAAAGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_032173 |
| Insert Size | 3300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_032173.1 |
| RefSeq Size | 6489 bp |
| RefSeq ORF | 477 bp |
| Locus ID | 84133 |
| UniProt ID | Q9ULT6 |
| Protein Families | Druggable Genome, Transmembrane |
| MW | 18.6 kDa |
| Gene Summary | E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone (PubMed:22575959). Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219546 | ZNRF3 (Myc-DDK-tagged)-Human zinc and ring finger 3 (ZNRF3), transcript variant 2 |
CNY 6,120.00 |
|
| RC219546L1 | Lenti ORF clone of Human zinc and ring finger 3 (ZNRF3), transcript variant 2, Myc-DDK-tagged |
CNY 8,520.00 |
|
| RC219546L2 | Lenti ORF clone of Human zinc and ring finger 3 (ZNRF3), transcript variant 2, mGFP tagged |
CNY 9,030.00 |
|
| RC219546L3 | Lenti ORF clone of Human zinc and ring finger 3 (ZNRF3), transcript variant 2, Myc-DDK-tagged |
CNY 8,520.00 |
|
| RC219546L4 | Lenti ORF clone of Human zinc and ring finger 3 (ZNRF3), transcript variant 2, mGFP tagged |
CNY 8,520.00 |
|
| RG219546 | ZNRF3 (tGFP-tagged) - Human zinc and ring finger 3 (ZNRF3), transcript variant 2 |
CNY 7,720.00 |
|
| SC318318 | ZNRF3 (untagged)-Human zinc and ring finger 3 (ZNRF3), transcript variant 2 |
CNY 16,250.00 |
