UNC5B (AK094595) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	p53RDL1; UNC5H2
Vector	pCMV6-XL6
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for AK094595 edited GAATTCGGCACGAGGCCACCATCTGCCCAGTCGATGGGGCGTGGACGGAGTGGAGCAAGT GGTCAGCCTGCAGCACTGAGTGTGCCCACTGGCGTAGCCGCGAGTGCATGGCGCCCCCAC CCCAGAACGGAGGCCGTGACTGCAGCGGGACGCTGCTCGACTCTAAGAACTGCACAGATG GGCTGTGCATGCAAAATAAGAAAACTCTAAGCGACCCCAACAGCCACCTGCTGGAGGCCT CAGGGGATGCGGCGCTGTATGCGGGGCTCGTGGTGGCCATCTTCGTGGTCGTGGCAATCC TCATGGCGGTGGGGGTGGTGGTGTACCGCCGCAACTGCCGTGACTTCGACACAGACATCA CTGACTCATCTGCTGCCCTGACTGGTGGTTTCCACCCCGTCAACTTTAAGACGGCAAGGC CCAGCAACCCGCAGCTCCTACACCCCTCTGTGCCTCCTGACCTGACAGCCAGCGCCGGCA TCTACCGCGGACCCGTGTATGCCCTGCAGGACTCCACCGACAAAATCCCCATGACCAACT CTCCTCTGCTGGACCCCTTACCCAGCCTTAAGGTCAAGGTCTACAGCTCCAGCACCACGG GCTCTGGGCCAGGCCTGGCAGATGGGGCTGACCTGCTGGGGGTCTTGCCGCCTGGCACAT ACCCTAGCGATTTCGCCCGGGACACCCACTTCCTGCACCTGCGCAGCGCCAGCCTCGGTT CCCAGCAGCTCTTGGGCCTGCCCCGAGACCCAGGGAGCAGCGTCAGCGGCACCTTTGGCT GCCTGGGTGGGAGGCTCAGCATCCCCGGCACAGGGGTCAGCTTGCTGGTGCCCAATGGAG CCATTCCCCAGGGCAAGTTCTACGAGATGTATCTACTCATCAACAAGGCAGAAAGTACCC TCCCGCTTTCAGAAGGGACCCAGACAGTATTGAGCCCCTCGGTGACCTGTGGACCCACAG GCCTCCTGCTGTGCCGCCCCGTCATCCTCACCATGCCCCACTGTGCCGAAGTCAGTGCCC GTGACTGGATCTTTCAGCTCAAGACCCAGGCCCACCAGGGCCACTGGGAGGAGGTGGTGA CCCTGGATGAGGAGACCCTGAACACACCCTGCTACTGCCAGCTGGAGCCCAGGGCCTGTC ACATCCTGCTGGACCAGCTGGGCACCTACGTGTTCACGGGCGAGTCCTATTCCCGCTCAG CAGTCAAGCGGCTCCAGCTGGCCGTCTTCGCCCCCGCCCTCTGCACCTCCCTGGAGTACA GCCTCCGGGTCTACTGCCTGGAGGACACGCCTGTAGCACTGAAGGAGGTGCTGGAGCTGG AGCGGACTCTGGGCGGATACTTGGTGGAGGAGCCGAAACCGCTAATGTTCAAGGACAGTT ACCACAACCTGCGCCTCTCCCTCCATGACCTCCCCCATGCCCATTGGAGGAGCAAGCTGC TGGCCAAATACCAGGAGATCCCCTTCTATCACATTTGGAGTGGCAGCCAGAAGGCCCTCC ACTGCACTTTCACCCTGGAGAGGCACAGCTTGGCCTCCACAGAGCTCACCTGCAAGATCT GCGTGCGGCAAGTGGAAGGGGAGGGCCAGATATTCCAGCTGCATACCACTCTGGCAGAGA CACCTGCTGGCTCCCTGGACACTCTCTGCTCTGCCCCTGGCAGCACTGTCACCACCCAGC TGGGACCTTATGCCTTCAAGATCCCACTGTCCATCCGCCAGAAGATATGCAACAGCCTAG ATGCCCCCAACTCACGGGGCAATGACTGGCGGATGTTAGCACAGAAGCTCTCTATGGACC GGTACCTGAATTACTTTGCCACCAAAGCGAGCCCCACGGGTGTGATCCTGGACCTCTGGG AAGCTCTGCAGCAGGACGATGGGGACCTCAACAGCCTGGCGAGTGCCTTGGAGGAGATGG GCAAGAGTGAGATGCTGGTGGCTGTGGCCACCGACGGGGACTGCTGAGCCTCCTGGGACA GCGGGCTGGCAGGGACTGGCAGGAGGCAGGTGCAGGGAGGCCTGGGGCAGCCTCCTGATG GGGATGTTTGGCCTCTGCTTCCTCCCAGTTCACAGCCAGAGTTGCCTCTCCTCCTCCTCT TCCCCAACCCCCAGACCATGACCAGCCTTAGAAAATCCATGTACTCTGTTGTTAGAGGGC CCAGAGTTCCTTCTCCACCCCCGCTCTCTCTCTCTTGGCCTGAGATCTCTGTGCAGGAAC CAAGATGGGGCTGAAGCCTCTGGAGGCAGTTGGTTGGGGGCGGGCAGGCAGGAGGCCCTC CCTCCACCCCCCCACCCTCAGCCCGGCAACTTCTGGGTTCCATGGGTTTTAGTTCCGTTC TTCGTTTTCTTCCTCCGTTATTGATTTCTCCTTTCTCCCTAAGCCCCCTTCTGCTTCCAC GCCCTTTTCCTCTTTGAAGAGTCAAGTACAATTCAGACAAACTGCTTTCTCCTGTCCAAA AGCAAAAAGGCAAAGGAAAGAAAGAAAGCTTCAGACCGCTAGTAAGGCTCAAAGAAGAAG AAAAACACCAAAACCACAAGGGAAAAGAAAAACCCAGTTTCTTAGGAAACGCAAACGATT TATTATCCAGATTATTTGGATAAGTCCTTTTTAAGAAAAAAAAAAAAAAAAAACTCGAC 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for AK094595 unedited NCTTATTACCCCCGCCCGTTCCCGCTTTGGGCGGTAGGCGTGTACGGTGGNGAGTCTATA TAAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGG CCGCGAATTCGGCACGAGGCCACCATCTGCCCAGTCGATGGGGCGTGGACGGAGTGGAGC AAGTGGTCAGCCTGCAGCACTGAGTGTGCCCACTGGCGTAGCCGCGAGTGCATGGCGCCC CCACCCCAGAACGGAGGCCGTGACTGCAGCGGGACGCTGCTCGACTCTAAGAACTGCACA GATGGGCTGTGCATGCAAAATAAGAAAACTCTAAGCGACCCCAACAGCCACCTGCTGGAG GCCTCAGGGGATGCGGCGCTGTATGCGGGGCTCGTGGTGGCCATCTTCGTGGTCGTGGCA ATCCTCATGGCGGTGGGGGTGGTGGTGTACCGCCGCAACTGCCGTGACTTCGACACAGAC ATCACTGACTCATCTGCTGCCCTGACTGGTGGTTTCCACCCCGTCAACTTTAAGACGGCA AGGCCCAGCAACCCGCAGCTCCTACACCCCTCTGTGCCTCCTGACCTGACAGCCAGCGCC GGCATCTACCGCGGACCCGTGTATGCCCTGCAGGACTCCACCGACAAAATCCCCATGACC AACTCTCCTCTGCTGGACCCCTTACCCAGCCTTAAGGTCAAGGTCTACAGCTCCAGCACC ACGGGCTCTGGGCCAGGCCTGGCAGATGGGGCTGACCTGCTGGGGGTCTTGCCGCCTGGC ACATACCCTAGCGATTTCGCCCGGGACACCCACTTCCTGCACCTGCGCAGCGCCAGCCCT CGGTTCCCAGCAGCTCCTTGGGCCTGNCCCGAGACCCAGGNAGCAGCGTCAGCGGCACCT TTGGCTGCCTG 3' Read Nucleotide Sequence (showhide) >OriGene 3' read for AK094595 unedited TCTTGGTATACTATGNACCGCGCCGCTATCTANGATCGATTTTTTTTTTTTTTTTTTCTT AAAAGGACTTATCCAAATAATCTGGATAATAAATCGTTTGCGTTTCCTAAGAAACTGGGT TTTTCTTTTCCCTTGTGGTTTTGGTGTTTTTCTTCTTCTTTGAGCCTTACTAGCGGTCTG AAGCTTTCTTTCTTTCCTTAGCCTTTTTGCTTTTGGACAGGAGAAAGCAGTTTGTCTGAA TTGTACTTGACTCTTCAAAGAGGAAAAGGGCGTGGAAGCAGAAGGGGGCTTAGGGAGAAA GGAGAAATCAATAACGGAGGAAGAAAACGAAGAACGGAACTAAAACCCATGGAACCCAGA AGTTGCCGGGCTGAGGGTGGGGGGGTGGAGGGAGGNNCCNCCNNCCNNCCCCCCCCCCAA CCACACCCCCCCCAACCCACAACCCCCGCCCCCNCCCCCCCCCCACCACCAGACCTCACA AAAACCACACCACCCACACACCAACACACGCCACTGAGCAACAACAAACCACCCAACACA AACGCCCACCCCCCCCCCACACACCCAACCACCACTAACCACCAGCATTTTNNNNNNNNA AANANNAGGACGCGGCCACAACANCCCCAAACCAACACAACCACACCACCCCCACACCCA AAGACCCCCCACCCCACCCCACCCCCACCACGGGCCGGGCGGAGGGAAACCACATACCGN NGGNGGNNANNGANGNNACCGCAGCCCCAAGAAAAGGAACAGCGCCAAAAACAACGCACC GCCAAAAGCATACCCACACCCGCNTCGCCGCAGAGGGGAATAAGAAGTCTCTTACTTTTA TACATATCCCACTCACACCAACCAACAGAGTATGTGGGGGGGGGGGATG
Restriction Sites	NotI-NotI
ACCN	AK094595
Insert Size	2750 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	AK094595.1, BAC04382.1
RefSeq Size	2406 bp
RefSeq ORF	2406 bp
Locus ID	219699
Domains	DEATH, ZU5
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Axon guidance
Gene Summary	This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]

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