United States
Germany
Japan
United Kingdom
China
CAVIN1 (NM_012232) Human Untagged Clone
CAT＃: SC101318
PTRF (untagged)-Human polymerase I and transcript release factor (PTRF)
CNY 3,656.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAVIN; cavin-1; CGL4; FKSG13; PTRF |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC101318 sequence for NM_012232 edited (data generated by NextGen Sequencing)
ATGGAGGACCCCACGCTCTATATTGTCGAGCGGCCGCTTCCCGGGTNNNCCGACGCCGAG GCCCCGGAGCCTTCCTCCGCTGGGGCTCAGGCAGCGGAGGAGCCGTCGGGGGCCGGCTCA GAAGAGCTGATCAAGTCGGACCAGGTGAACGGCGTGCTGGTGCTGAGCCTCCTGGACAAA ATCATCGGGGCCGTAGACCAGATCCAGCTGACTCAAGCACAGCTGGAGGAGCGGCAGGCG GAGATGGAGGGCGCAGTGCAGAGCATCCAGGGCGAGCTGAGCAAGCTGGGCAAGGCGCAC GCCACCACGAGCAATACGGTGAGCAAGCTGCTGGAGAAGGTGCGCAAGGTCAGCGTCAAC GTGAAGACCGTGCGCGGCAGCCTGGAGCGCCAGGCGGGGCAGATCAAGAAGCTGGAGGTC AACGAGGCCGAGCTGCTGCGGCGCCGCAACTTTAAAGTCATGATCTACCAGGATGAAGTG AAGCTGCCGGCCAAACTGAGCATCAGCAAATCGCTGAAAGAGTCGGAGGCGCTGCCAGAG AAGGAGGGCGAGGAGCTGGGCGAGGGCGAGCGGCCCGAGGAGGACGCAGCGGCGCTGGAG CTTTCGTCGGACGAGGCGGTGGAGGTTGAGGAGGTTATTGAGGAGTCCCGCGCAGAGCGT ATCAAGCGCAGCGGCCTGCGGCGCGTGGACGACTTCAAGAAGGCCTTCTCCAAGGAGAAG ATGGAGAAGACCAAGGTGCGTACCCGCGAGAACCTGGAGAAGACGCGCCTCAAGACCAAG GAAAACCTGGAGAAGACGCGGCACACCCTGGAGAAGCGCATGAACAAGCTGGGCACGCGC CTGGTGCCCGCCGAGCGGCGCGAGAAACTGAAGACGTCGCGGGACAAGTTGCGCAAATCC TTCACGCCCGACCACGTGGTGTACGCGCGCTCCAAGACCGCGGTCTACAAGGTGCCACCC TTCACCTTCCACGTCAAGAAGATCCGCGAGGGCCAGGTGGAAGTGCTCAAGGCCACCGAG ATGGTGGAGGTGGGCGCCGACGACGACGAGGGCGGCGCGGAGCGCGGGGAGGCCGGCGAC CTGCGGCGCGGGAGCAGCCCCGACGTGCACGCGCTGCTGGAGATCACCGAGGAGTCGGAC GCCGTGCTGGTGGACAAGAGCGACAGCGACTGA Clone variation with respect to NM_012232.5 47 a=>n;48 c=>n;49 c=>n >OriGene 5' read for NM_012232 unedited
CAATCCCCCGCCCGTTGACGCAATGGGCGGTAGGCGTGTCCGGTGGGAGGTCTATATAAG CAGAGCTCATTTAGGTGACACTATAGGGGACAGGCTACTTGTTCTTTTTGCAGCGGCCGC GAATTCGGCACGAGGGTCCCGGTGCGCACGGACGTGGCTCGAGTTTCCTCTGCTCTCCGC TCTCGCCCGCTAGCTCTCCTCCCTTCCGCTCCTGCTTCTCTCCGGGTCTCCCGCTCCAGC TCCAGGGCGACCCGGCCGGTCCCGCACGGCTCCGGGTAGCCATGGAGGACCCCACGCTCT ATATTGTCGAGCGGCCGCTTCCCGGGTACCCCGACGCCGAGGCCCCGGAGCCTTCCTCCG CTGGGGCTCAGGCAGCGGAGGAGCCGTCGGGGGCCGGCTCAGAAGAGCTGATCAAGTCGG ACCAGGTGAACGGCGTGCTGGTGCTGAGCCTCCTGGACAAAATCATCGGGGCCGTAGACC AGAGCCAGCTGACTCAAGCACAGCTGGAGGAGCGGCAGGCGGAGATGGAGGGCGCAGTGC AGAGCATCCAGGGCGAGCTGAGCAAGCTGGGCAAGGCGCACGCCACCACGAGCAATACGG TGAGCAAGCTGCTGGAGAAGGTGCGCAAGGTCAGCGTCAACGTGAAGACCGTGCGCGGCA GCCTGGAGCGCCAGGCGGNGCAGATCAAGAAGCTGGAGGTCAACGAGGCCGAGCTGCTGC GGCGCCGCAACTTTAAAGTCATGATCTACCAGGATGAAGTGAAGCTGCCTGCCAAACTGA GCATCAGCAAATCGCTGAAAGAGTCTGAGGCGCTGCCANAAACNGAGGCTAGGAGCATGG CTAGGGCTAGCTGCCCTAGGAGACGCACGGCGCTGGAGCTATCTCGACGAGCGGTGGAGG TTAGGAGGTATTGAGGAGTCCTCGCANACGTATCAGCCT >OriGene 3' read for NM_012232 unedited
AAACTTTTGANAGACAGTTTATTGGTCGGGCTGCTCACCAGGACACAGCAACGTGAGCAG TTCCCCAAGCCCCATAAAATGCATCTGCCCACAGCTCAGGCCCCTTCAGGCCATCAGCAC CAAGGGACCTTGTCCCACAATCCCCAACCTCCCTCGGCAGAGGGGTCTTCAGCCATTCAG AGGAGAGAAGAGAACCGAGAAAGGGAAAAGGAAGAAAAAAAAAAAAAAAGCAAAGCTTTG TATTGTATAAAAGGTTTGTGTCCCCAGGCTCCCTCCCCCAATCCCTTAAAACAATGAACT GCAGTTCTAAAAAGCAGGGCAGAGAAGGTAAGGAGCAGGTGGGGGGAAGGAGGAAGCTCT CGGGGCCTCCCTTCAGGCTGTGACTGGGGAGAGGGGCTGTTCTTGCTTCTGACAAACCCC CTTTAATGGGGAGGAACAAGGGGACTCGTGTCTTGAGAACCTGGTCGTGTCTTGAGAACC CAGTCCGAACAGAATCAGGCCTCTGGACTGGGAGCAACACTCCCTTCACCCCCAAAGATT CAGGAAAAGCACCCCAAGGACAAGGAAACCAATGAGGTCTGGGCTAGCTCTGCAGCTTTA GGATACTAGCTCTAGGGAAGGATTTTTTCCTTTTTAAACAGCGTCTCACTCTGTTGCCTA GGATGGAGCACAGAGGCACCCTCATAGCTCACTGCAGCCTCAAACTCCTGGGCTCTGGCG ATCCTCCCGCCTCAGCCTCCCAAGTAGCTGAGACCACAGGCACGTGCCACCATGCTCCTA GGGAAGGAGCTTGAGAATGAACTGCCAGGAGTGAACCAGGGCTGGCTGCTCTGTGATGTT CTCTCCCCACCTCCCCTTCAGCTCTCAACTTGGTGGCAGGGCCGGCACCCTGCTCTNCCT CCTAACTNCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_012232 |
| Insert Size | 4200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_012232.2, NP_036364.2 |
| RefSeq Size | 3580 bp |
| RefSeq ORF | 1173 bp |
| Locus ID | 284119 |
| UniProt ID | Q6NZI2 |
| Protein Families | Transcription Factors |
| Gene Summary | This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. [provided by RefSeq, Nov 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Proteomic identification of a marker signature for MAPKi resistance in melanoma
,null,
The EMBO Journal
,PubMed ID 31267558
[CAVIN1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209277 | PTRF (Myc-DDK-tagged)-Human polymerase I and transcript release factor (PTRF) |
CNY 3,656.00 |
|
| RC209277L3 | Lenti ORF clone of Human polymerase I and transcript release factor (PTRF), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC209277L4 | Lenti ORF clone of Human polymerase I and transcript release factor (PTRF), mGFP tagged |
CNY 5,890.00 |
|
| RG209277 | PTRF (tGFP-tagged) - Human polymerase I and transcript release factor (PTRF) |
CNY 5,256.00 |
