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CLEC14A (NM_175060) Human Untagged Clone
CAT＃: SC101279
CLEC14A (untagged)-Human C-type lectin domain family 14, member A (CLEC14A)
CN¥ 3,656.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C14orf27; CEG1; EGFR-5 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC101279 sequence for NM_175060 edited (data generated by NextGen Sequencing)
ATGAGGCCGGCGTTCGCCCTGTGCCTCCTCTGGCAGGCGCTCTGGCCCGGGCCGGGCGGC GGCGAACACCCCACTGCCGACCGTGCTGGCTGCTCGGCCTCGGGGGCCTGCTACAGCCTG CACCACGCTACCATGAAGCGGCAGGCGGCCGAGGAGGCCTGCATCCTGCGAGGTGGGGCG CTCAGCACCGTGCGTGCGGGCGCCGAGCTGCGCGCTGTGCTCGCGCTCCTGCGGGCAGGC CCAGGGCCCGGAGGGGGCTCCAAAGACCTGCTGTTCTGGGTCGCACTGGAGCGCAGGCGT TCCCACTGCACCCTGGAGAACGAGCCTTTGCGGGGTTTCTCCTGGCTGTCCTCCGACCCC GGCGGTCTCGAAAGCGACACGCTGCAGTGGGTGGAGGAGCCCCAACGCTCCTGCACCGCG CGGAGATGCGCGGTACTCCAGGCCACCGGTGGGGTCGAGCCCGCAGGCTGGAAGGAGATG CGATGCCACCTGCGCGCCAACGGCTACCTGTGCAAGTACCAGTTTGAGGTCTTGTGTCCT GCGCCGCGCCCCGGGGCCGCCTCTAACTTGAGCTATCGCGCGCCCTTCCAGCTGCACAGC GCCGCTCTGGACTTCAGTCCACCTGGGACCGAGGTGAGTGCGCTCTGCCGGGGACAGCTC CCGATCTCAGTTACTTGCATCGCGGACGAAATCGGCGCTCGCTGGGACAAACTCTCGGGC GATGTGTTGTGTCCCTGCCCCGGGAGGTACCTCCGTGCTGGCAAATGCGCAGAGCTCCCT AACTGCCTAGACGACTTGGGAGGCTTTGCCTGCGAATGTGCTACGGGCTTCGAGCTGGGG AAGGACGGCCGCTCTTGTGTGACCAGTGGGGAAGGACAGCCGACCCTTGGGGGGACCGGG GTGCCCACCAGGCGCCCGCCGGCCACTGCAACCAGCCCCGTGCCGCAGAGAACATGGCCA ATCAGGGTCGACGAGAAGCTGGGAGAGACACCACTTGTCCCTGAACAAGACAATTCAGTA ACATCTATTCCTGAGATTCCTCGATGGGGATCACAGAGCACGATGTCTACCCTTCAAATG TCCCTTCAAGCCGAGTCAAAGGCCACTATCACCCCATCAGGGAGCGTGATTTCCAAGTTT AATTCTACGACTTCCTCTGCCACTCCTCAGGCTTTCGACTCCTCCTCTGCCGTGGTCTTC ATATTTGTGAGCACAGCAGTAGTAGTGTTGGTGATCTTGACCATGACAGTACTGGGGCTT GTCAAGCTCTGCTTTCACGAAAGCCCCTCTTCCCAGCCAAGGAAGGAGTCTATGGGCCCG CCGGGCCTGGAGAGTGATCCTGAGCCCGCTGCTTTGGGCTCCAGTTCTGCACATTGCACA AACAATGGGGTGAAAGTCGGGGACTGTGATCTGCGGGACAGAGCAGAGGGTGCCTTGCTG GCGGAGTCCCCTCTTGGCTCTAGTGATGCATAG Clone variation with respect to NM_175060.1 >OriGene 5' read for NM_175060 unedited
CCCATTCACCCGCCCGTTGACGCAATGGGCGGTAGGCGTGTCCGGTGGGAGGTCTATATA AGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCC GCGAATTCGGCACGAGGGTCCTCGAGCGGGACAGATCTAAGTTGGGAGCAGCTCTGCGTG CGGGGCCTCAGAGAATGAGGCCGGCGTTCGCCCTGTGCCTCCTCTGGCAGGCGCTCTGGC CCGGGCCGGGCGGCGGCGAACACCCCACTGCCGACCGTGCTGGCTGCTCGGCCTCGGGGG CCTGCTACAGCCTGCACCACGCTACCATGAAGCGGCAGGCGGCCGAGGAGGCCTGCATCC TGCGAGGTGGGGCGCTCAGCACCGTGCGTGCGGGCGCCGAGCTGCGCGCTGTGCTCGCGC TCCTGCGGGCAGGCCCAGGGCCCGGAGGGGGCTCCAAAGACCTGCTGTTCTGGGTCGCAC TGGAGCGCAGGCGTTCCCACTGCACCCTGGAGAACGAGCCTTTGCGGGGTTTCTCCTGGC TGTCCTCCGACCCCGGCGGTCTCGAAAGCGACACGCTGCAGTGGGTGGAGGAGCCCCAAC GCTCCTGCACCGCGCGGAGATGCGCGGTACTCCAGGCCACCGGTGGGGTCGAGCCCGCAG GCTGNGAGGAGATGCGATGCCACCTGCGCGCCAACGGCTACCTGTGCTAGTACCAGTTTG AGGTCTTGTGTCCTGCGCCGCGCCCCGGGGCCGCCTCTAACTTGAGCTATCGCGCGCTCT TCCAGCTGCACAGCGCCGCTCTGGACTACAGTCCACCTGGGACCGAGGTGAGTGCGCTCT GCCGGGGACAGCTNCCGATCTCAGATACTTGCATCGCGGACGAAATCGCGCTCGCTGGGA CAACTCTCGGCCGAAGNGATGGGTCCCTGCCCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_175060 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_175060.1, NP_778230.1 |
| RefSeq Size | 2256 bp |
| RefSeq ORF | 1473 bp |
| Locus ID | 161198 |
| UniProt ID | Q86T13 |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Sprouting angiogenesis is regulated by shedding of the C-type lectin family 14, member A (CLEC14A) ectodomain, catalyzed by rhomboid-like 2 protein (RHBDL2)
,Noy, PJ;Swain, RK;Khan, K;Lodhia, P;Bicknell, R;,
FASEB J.
,PubMed ID 26939791
[CLEC14A]
|
|
Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth
,Noy, PJ;Lodhia, P;Khan, K;Zhuang, X;Ward, DG;Verissimo, AR;Bacon, A;Bicknell, R;,
Oncogene
,PubMed ID 25745997
[CLEC14A]
|
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206655 | CLEC14A (Myc-DDK-tagged)-Human C-type lectin domain family 14, member A (CLEC14A) |
CN¥ 3,656.00 |
|
| RC206655L3 | Lenti ORF clone of Human C-type lectin domain family 14, member A (CLEC14A), Myc-DDK-tagged |
CN¥ 5,890.00 |
|
| RC206655L4 | Lenti ORF clone of Human C-type lectin domain family 14, member A (CLEC14A), mGFP tagged |
CN¥ 6,056.00 |
|
| RG206655 | CLEC14A (tGFP-tagged) - Human C-type lectin domain family 14, member A (CLEC14A) |
CN¥ 5,256.00 |
|
| SC324279 | CLEC14A (untagged)-Human C-type lectin domain family 14, member A (CLEC14A) |
CN¥ 3,656.00 |
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