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AIF (AIFM1) (NM_145813) Human Untagged Clone
CAT＃: SC100268
AIFM1 (untagged)-Human apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1), transcript variant 3
CNY 2,400.00
CNY 6,270.00
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AIF; CMT2D; CMTX4; COWCK; COXPD6; NADMR; NAMSD; PDCD8 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_145813, the custom clone sequence may differ by one or more nucleotides
ATGTTCCGGTGTGGAGGCCTGGCGGCGGGTGCTTTGAAGCAGAAGCTGGTGCCCTTGGTGCGGACCGTGT GCGTCCGAAGCCCGAGGCAGAGGAACCGGCTCCCAGCTCGAGCCTTGGGCACAGAAGTGATTCAACTCTT CCCCGAGAAAGGAAATATGGGAAAGATCCTCCCCGAATACCTCAGCAACTGGACCATGGAAAAAGTCAGA CGAGAGGGGGTTAAGGTGATGCCCAATGCTATTGTGCAATCCGTTGGAGTCAGCAGTGGCAAGTTACTTA TCAAGCTGAAAGACGGCAGGAAGGTAGAAACTGACCACATAGTGGCAGCTGTGGGCCTGGAGCCCAATGT TGAGTTGGCCAAGACTGGTGGCCTGGAAATAGACTCAGATTTTGGTGGCTTCCGGGTAAATGCAGAGCTA CAAGCACGCTCTAACATCTGGGTGGCAGGAGATGCTGCATGCTTCTACGATATAAAGTTGGGAAGGAGGC GGGTAGAGCACCATGATCACGCTGTTGTGAGTGGAAGATTGGCTGGAGAAAATATGACTGGAGCTGCTAA GCCGTACTGGCATCAGTCAATGTTCTGGAGTGATTTGGGCCCCGATGTTGGCTATGAAGCTATTGGTCTT GTGGACAGTAGTTTGCCCACAGTTGGTGTTTTTGCAAAAGCAACTGCACAAGACAACCCCAAATCTGCCA CAGAGCAGTCAGGAACTGGTATCCGATCAGAGAGTGAGACAGAGTCCGAGGCCTCAGAAATTACTATTCC TCCCAGCACCCCGGCAGTTCCACAGGCTCCCGTCCAGGGGGAGGACTACGGCAAAGGTGTCATCTTCTAC CTCAGGGACAAAGTGGTCGTGGGGATTGTGCTATGGAACATCTTTAACCGAATGCCAATAGCAAGGAAGA TCATTAAGGACGGTGAGCAGCATGAAGATCTCAATGAAGTAGCCAAACTATTCAACATTCATGAAGACTG A >OriGene 5' read for NM_145813 unedited
NGGGGGTTCGAGATTTGTATACGATTCATATAGGGCGGCCGCGAATTCGCACGAGGTCGC CGTTCCCCTTCCCCGGCTCTAGCAGGCCGGCTTCTCTGTCCAATGCCCACCCGGAGCTGG GAGGAGGAGTCTGCGTAATGTGCGTGTGAAGAGACTGGGGGAGCTGGCCGGGGCTCACGG TGTTTGACCCGTCGGTCGTGCGTGAGAGGAAAGGGAAGGAGGAGGTCCCGAATAGCGGTC GCCGAAATGTTCCGGTGTGGAGGCCTGGCGGCGGGTGCTTTGAAGCAGAAGCTGGTGCCC TTGGTGCGGACCGTGTGCGTCCGAAGCCCGAGGCAGAGGAACCGGCTCCCAGGCAACTTG TTCCAGCGATGGCATGTTCCTCTAGAACTCCAGATGACAAGACAAATGGCTAGCTCTGGT GCATCAGGGGGCAAAATCGATAATTCTGTGTTAGTCCTTATTGTGGGCTTATCAACAGTA GGAGCTGGTGCCTATGCCTACAAGACTATGAAAGAGGATGAAAAAAGATACAATGAAAGA ATTTCAGGGTTAGGGCTGACACCAGAACAGAAACAGAAAAAGGCCGCGTTATCTGCTTCA GAAGGAGAGGAAGTTCCTCAAGACAAGGCGCCAAGTCATGTTCCTTTCCTGCTAATTGGT GGAGGCACAGCTGCTTTTGCTGCAGCCAGATCCATCCGGGCTCGGGATCCTGGGGCCAGG GTACTGATTGTATCTGAAGATCCTGAGCTGCCGTACATGCGACCTCCTCTTTCAAAAAAC TGTGGTTTTCAGATGACCCAAATGTCACAAAGACACTGCGATTCAAACAGTGGAATGGNA AAAGAGAAAGCATATATTTCCAGCCACCTTCTTCTATGTCTCTGCTCAGGACTGNCT >OriGene 3' read for NM_145813 unedited
GGCTCCTTTATGNACCGCGGTCCGCAATTCTANATCTCGAGTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAAAAATCAAAATTTATTTCACTATGGGAA CCTTAAAAATTTACCTACCTAGTTGAAAATATTCACAAAGGACTTGATCATTCACACTCA TACCCAGAGAAAGTCTGCTGAATAAAAAAATGCTCCTTTACCCATTCGACCTCCTCTCAA GGGCTGCAGGGGGTTTGCCAATTCCACTGGGGGGCTTCAGTCTTCATGAATGTTGAATAG TTTGGCTACTTCATTGAGATCTTCATGCTACTCACCGGCCTTAATGATCTTCCTTGCTAT TGGCATTCGGTTAAAGATGTTCCATAACACAATCCCCACGACCACTTTGTCCCTGAGGTA AAAAATGACACCTTTGCCGTAGTCCTCCCCCTGGACGGGAGCCTGTGGAACTGCCGGGGT GCTGGGAGGAATAGTAATTTCTGAGGCCTCGGACTCTGTCTCACTCTCTGATCGGATACC AATTCCTGACTGCTCTGTGGCAAATTTGGGGTTGTCTTGTGCAGTTGCTTTTGCAAAAAC ACCAACTGTGGGCAAACTACTGTCCACAAGACCAATAGCTTCATAGCCAACATCGGGGCC CAAATCACTCCAGAACATTGACTGATGCCAGTACGGCTTAACAGCTCCAGTCATATTTTC TCCAGCCAATCNTCCACTCACACAGCGTGATCATGGTGCTCTACCCGCCTTCTTCCCAAT TTATATCGTAAAAGCCTGCAGCATCTCCTGCCACCCAAATGTTAAAGCGTGCTTGTAGCT CTGCCTTTACCCCGGAGCCACCCAAATCTGATCTATTTCCAGCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_145813 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_145813.1, NP_665812.1 |
| RefSeq Size | 1354 bp |
| RefSeq ORF | 981 bp |
| Locus ID | 9131 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Apoptosis |
| Gene Summary | This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015] Transcript Variant: This variant (3) lacks several in-frame exons in the 5' coding region compared to variant 1, resulting in an isoform (3) that is 287 aa shorter than isoform 1. |
Documents
| Product Manuals |
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216357 | AIFM1 (Myc-DDK-tagged)-Human apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1), transcript variant 3 |
CNY 3,990.00 |
|
| RC216357L3 | Lenti-ORF clone of AIFM1 (Myc-DDK-tagged)-Human apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1), transcript variant 3 |
CNY 5,890.00 |
|
| RC216357L4 | Lenti-ORF clone of AIFM1 (mGFP-tagged)-Human apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1), transcript variant 3 |
CNY 5,890.00 |
|
| RG216357 | AIFM1 (tGFP-tagged) - Human apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1), transcript variant 3 |
CNY 4,240.00 |
